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7070774 |
Antibodies that bind testis-specific insulin homolog polypeptides
The present invention provides testis-specific insulin homolog polypeptides and polynucleotides encoding the polypeptides, as well as related compositions and methods are disclosed. The...
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7067636 |
Anti-pro 1017 antibodies
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid...
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7067637 |
Antibody or antibody fragments specific for a protein of the TGF-β family
The invention provides antibody and antibody fragments which specifically bind to novel members of the TGF-β family of proteins. The TFG-β family comprises proteins which function as growth...
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7067314 |
Monoclonal antibody, its immunoreactive fragment and hybridoma
It is an object to utilize a novel HSCA-3 antigen occurring in immature hemopoietic stem cells and a monoclonal antibody recognizing said antigen in 1) the immunoassay or flow cytometry involving...
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7067635 |
Nucleotide and deduced amino acid sequences of tumor gene Int6
The present invention discloses the isolation of the human and murine wild-type Int6 gene and the cDNAs sorresponding to these genes. The invention further describes the use of reagents derived...
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7063842 |
Compounds and methods for inhibiting the interaction between α-catenin and β-catenin
Modulating agents for inhibiting an interaction between α-catenin and β-catenin are provided. The modulating agents comprise one or more of: (a) a β-catenin HAV motif; (b) a peptide analogue or...
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7060796 |
Antibody directed against purified β 1,2-xylosyltransferase
The present invention provides a purified, homogeneous plant enzyme that adds a β-1,2-linked xylose to the β-linked mannose on the N-linked oligosaccharides of storage glycoproteins. This...
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7060800 |
Antibodies binding the TNF related protein, TNF-X
Nucleic acids encoding mammalian, e.g., primate or rodent, genes, purified proteins and fragments thereof. Antibodies, both polyclonal and monoclonal, are also provided. Methods of using the...
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7060801 |
Antibodies to human growth factor huXAG-3 and methods of use
The present invention relates to huXAG-1, huXAG-2 and huXAG-3 proteins which are novel human growth factors. In particular, isolated nucleic acid molecules are provided encoding the huXAG-1,...
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7057022 |
Antibodies which specifically bind to TNF-R
Tumor necrosis factor receptor proteins, DNAs and expression vectors encoding TNF receptors, and processes for producing TNF receptors as products of recombinant cell culture, are disclosed.
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7056681 |
Interleukin-19 antibodies
The present invention concerns a novel human cytokine. In particular, isolated nucleic acid molecules are provided encoding interleukin-19 (IL-19). IL-19 polypeptides are also provided, as are...
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7056680 |
Antibodies to claudin-50 polypeptide
The sequence of a cDNA encoding Claudin-50 and sequence of Claudin-50 protein are disclosed. The cDNA can be used to express the protein or portions thereof or to obtain antibodies capable of...
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7053182 |
Genes regulating circadian clock functional and photoperiodism
Nucleic acid molecules that encode plant proteins involved in photoperiodism and circadian rhythms are disclosed. These molecules may be introduced into plants in order to alter the photoperiodic...
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7053189 |
Human dopamine receptor and its uses
The present invention is directed toward antibodies, particularly monoclonal antibodies, which bind specifically to a novel human D4 dopamine receptor in sensitive and specific immunological assays...
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7049408 |
Antibody reactive with a protein having pre-B cell growth-supporting ability
A gene encoding a novel membrane protein polypeptide having pre-B cell growth-supporting ability and a membrane protein polypeptide consisting of 180 amino acid residues having pre-B cell...
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7049407 |
Heparanase specific antibodies and their use in research and medical applications
A variety of heparanase specific antibodies which can be used for research and medical applications including diagnosis and therapy. Specific applications include the use of a heparanase specific...
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7045604 |
Family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof
An isolated polynucleotide at least 60% homologous to SEQ ID NO: 1, 3, 5 or 18 encoding a SARP polypeptide; vectors comprising a polynucleotide sequence encoding at least 11 consecutive amino acids...
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7045333 |
Human protease molecules
The invention provides human protease molecules (HUPM) and polynucleotides which identify and encode HUPM. The invention also provides expression vectors, host cells, antibodies, agonists, and...
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7045128 |
Antibodies against flt3-ligand
Ligands for flt3 receptors capable of transducing self-renewal signals to regulate the growth, proliferation or differentiation of progenitor cells and stem cells are disclosed. The invention is...
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7045602 |
Specific antibody directed to active hepatocyte growth factor activator and method for using the same
An antibody which recognizes an active hepatocyte growth factor activator (HGFA) and does not substantially recognize inactive HGFA is provided. Also disclosed is a monoclonal antibody thereof, and...
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7041804 |
Antibodies to PRO1387 polypeptides
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising these nucleic acid...
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7041460 |
Antibodies to monocyte-colony inhibitory factor (M-CIF)
There are disclosed therapeutic compositions and methods using isolated nucleic acid molecules encoding a human myeloid progenitor inhibitory factor-1 (MPIF-1) polypeptide (previously termed MIP-3...
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7041806 |
Netrin receptors
The invention provides methods and compositions relating to vertebrate UNC-5 proteins which function as receptor proteins for netrins, a family of cell guidance proteins. The proteins may be...
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7041801 |
Antibodies binding to polypeptides encoded by developmentally-regulated endothelial cell locus-1
The present invention relates to a member of a novel gene family referred to as developmentally-regulated endothelial cell locus-1 (del-1). In particularly, the invention related to del-1...
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7038019 |
Antibodies to PRO1410
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid...
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7034121 |
Antibodies against CTLA4
The invention provides an antibody-toxic moiety conjugates comprising an antibody that specifically recognizes a molecule expressed on the surface of a T cell which is expressed only on T cells and...
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7034123 |
Anti-PRO1347 antibodies
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid...
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7034122 |
Antibodies to PRO1159 polypeptides
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid...
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7029862 |
Method for identifying ligands, inhibitors or promoters of CXC chemokine receptor 3
The invention relates to methods of identifying ligands, and inhibitors (e.g., antagonists) or promoters (e.g., agonists) of receptor function, including methods in which host cells comprising a...
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7029864 |
Antibody against cleavage product of vimentin
The present invention provides the antibody that react with the cleavage product of vimentin, but not with intact vimentin.
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7029866 |
Cancer diagnosis by the measurement of Nup88 in body samples
The invention is directed to a method of diagnosis of the existence and/or the pathological developmental stage and/or the grade of malignancy of carcinomas and/or sarcomas in mammals characterized...
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7030227 |
Cell regulatory genes, encoded products, and uses related thereto
This application describes the cloning of p63, a gene at chromosome 3q27-29, that bears homology to the tumor suppressor p53. The p63 gene encodes at least six different isotypes. p63 was detected...
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7026283 |
Calcium-independent negative regulation by CD81 of receptor signalling
Calcium independent CD81 inhibition of IgE-mediated degranulation in mast cells, particularly through the FcγRIII and FcεRI receptors, is described, as well as methods of inhibiting allergic...
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7026457 |
Purified hepatitis C virus envelope proteins for diagnostic and therapeutic use
The present invention relates to a method for purifying recombinant HCV single or specific oligomeric envelope proteins selected from the group consisting of E1 and/or E1/E2 characterized in that...
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7026129 |
IG lambda biopolymer markers predictive of Alzheimers disease
The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers...
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7026455 |
Anti-pro 1343 antibodies
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid...
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7022821 |
Antibody kit for the detection of TADG-15 protein
The present invention provides DNA encoding a TADG-15 protein as well as a TADG-15 protein. Also provided is a vector capable of expressing the DNA of the present invention adapted for expression...
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7014853 |
Family of immunoregulators designated leukocyte immunoglobulin-like receptors (LIR)
A new family of immunoreceptor molecules of the immunoglobulin superfamily, (LIR) polypeptides is described. Disclosed are sequences encoding LIR family members and their deduced amino acid...
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7015311 |
Neurturin antibody
A novel growth factor, neurturin, is disclosed and the human and mouse amino acid sequences are identified. Human and mouse neurturin genomic DNA sequences have been cloned and sequenced and the...
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7015004 |
Inter-alpha trypsin inhibitor biopolymer marker indicative of insulin resistance
The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers...
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7012134 |
Dendritic enriched secreted lymphocyte activation molecule
The present invention relates to a novel human protein called Dendritic Enriched Secreted Lymphocyte Activation Molecule, and isolated polynucleotides encoding this protein. Also provided are...
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7008622 |
Methods and compositions for impairing multiplication of HIV-1
A composition which elicits antibodies to greater than 95%, and even greater than 99%, of the known variants of HIV-1 Tat protein contains at least one peptide or polypeptide of the formula of...
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7001992 |
Antibodies to secreted protein HEMCM42
The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells,...
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6995005 |
Enzyme which cleaves ester groups and which is derived from Thermononospora fusca
The invention relates to an ester-group-cleaving enzyme obtainable by culturing the microorganism Thermomonospora fusca in a suitable nutrient medium, optionally in the presence of an inducer.
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6995243 |
Antibodies that recognize and bind phosphorylated human glucocorticoid receptor and methods of using same
A molecule containing the antigen binding portion of an antibody specific for human glucocorticoid receptor phosphorylated at residue Ser211, Ser226 or Ser203 is obtained and a method of...
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6989145 |
Recombinant antibody and antibody fragment
A recombinant antibody or the antibody fragment thereof which specifically reacts with an extracellular domain of human CCR4; a DNA which encodes the recombinant antibody or the antibody fragment...
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6984720 |
Human CTLA-4 antibodies
The present invention provides human sequence antibodies against CTLA-4 and methods of treating human diseases, infections and other conditions using these antibodies.
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6982156 |
Compositions and methods modulating variola and vaccinia virus
Antibodies directed to SPICE and VCP which may be used for detection, prevention, and treatment of variola virus or vaccinia virus are provided. Recombinant SPICE and VCP proteins are also provided...
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6982317 |
C21 polypeptide that modulates the stability of transcriptional regulatory complexes regulating nuclear hormone receptor activity
A gene in humans and mice, designated C21, encodes a family of proteins that play a role in transcriptional regulation. Two isoforms (α and β) produced by alternative splicing has been identified...
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RE38916 |
APC Antibodies
A human gene termed APC is disclosed. Methods and kits are provided for assessing mutations of the APC gene in human tissues and body samples. APC mutations are found in familial adenomatous...
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