|
Match
|
Document |
Document Title |
|
|
7544368 |
Structure for modulating intraocular pressure
Embodiments of the present invention are directed to three-dimensional porous structures for modulating intraocular pressure. The structures can include a mixture of copolymers, for example,...
|
|
|
7531631 |
Method for preparing human serum albumin through heat-treatment in the presence of divalent cation
The present invention herein discloses a method for purifying human serum albumin, which is characterized in that it comprises the steps of heat-treating a human serum albumin-containing solution...
|
|
|
7423124 |
Method for albumin purification
The present invention is a method of purifying recombinant human serum albumin (rHSA) from a solution, which method comprises to subject a cell culture supernatant (CCS) comprising rHSA cation...
|
|
|
7351801 |
Method, use and kit for separating albumin from contaminants in a liquid
The present invention is a method of separating recombinant human serum albumin (rHSA) from low molecular weight contaminants in a liquid, which method comprises the steps of: (a) providing a...
|
|
|
7332577 |
Therapeutic human albumin solutions with low prekallikrein activator (PKA) activity and process for obtaining them
The invention discloses a purified albumin solution of human origin with low prekallicrein activator (PKA) activity and stability over time characterised in that it has an antithrombin content...
|
|
|
7307148 |
Method for purification of albumin conjugates
The present invention relates to a method for separating albumin conjugate from unconjugated albumin in a solution comprising albumin conjugate and unconjugated albumin by loading the solution onto...
|
|
|
7087719 |
Method for the crystallization of human serum albumin
The present invention relates to the purification and production of human albumin from various sources through crystallization and repeated crystallization. Basic features of the invented process...
|
|
|
7041798 |
Method for the chromatographic fractionation of plasma or serum, preparations, so obtained, and their use
The invention relates to the fractionation of plasma or serum into at least one albumin fraction and one immunoglobulin fraction by hydrophobic interaction chromatography. The fractionation is...
|
|
|
6951644 |
Adsorbent for peptidoglycan and method and apparatus for adsorptively removing peptidoglycan
An adsorbent for peptidoglycan which comprises an water-insoluble porous material having an amino group and having a molecular weight of exclusion limit of at least 50,000, and a method for...
|
|
|
6906183 |
Process for the separation of glycosylated and nonglycosylated proteins
A process for the partial or complete separation of glycosylated and nonglycosylated proteins is described, in which: a) a triazine dye immobilized on a matrix is incubated with a mixture of...
|
|
|
6867193 |
Amino acid-containing albumin preparation
An albumin preparation that prevents onset of hepatic encephalopathy caused by conventional amino acid preparations and enhances an effect of improving the symptoms is provided. The albumin...
|
|
|
6693173 |
Method to remove citrate and aluminum from proteins
A method is provided for removing citrate, aluminum, and other multivalent ions and contaminants from proteins by adjusting the pH of a solution containing the protein to a pH from about 7 to about...
|
|
|
6617133 |
Process for purifying recombinant human serum albumin
The invention provides a process for purifying recombinant human serum albumin (rHSA) by heating a-culture medium containing rHSA and the rHSA-producing host cells, feeding said heated solution...
|
|
|
6613884 |
Method for the removal/purification of serum albumins and means for use in the method
A method for removing a serum albumin from a mixture of other compounds by contacting said mixture with a ligand a) having affinity for and enabling selective binding of the serum albumin and b)...
|
|
|
6528622 |
Method of separating and recovering proteins from a protein solution
A preparative method of isolating a preselected whey protein or group of whey proteins from a solution is provided. The method comprises the following steps: (a) contacting a whey protein solution...
|
|
|
6500918 |
Conjugate comprising an antinociceptive agent covalently bonded to a blood component
Conjugates are prepared from antinociceptive agents, particularly opioids or opioid analogs, more particularly dynorphins, endorphins, deltorphins, enkephalins or analogs thereof, by combining said...
|
|
|
6489443 |
Process for the preparation of a protein solution
A process for the preparation of a protein solution is described which is not prone to flock or particle formation even on heat treatment, the heat treatment being carried out in a glass vessel...
|
|
|
6485935 |
Structure of the ankyrin binding domain of a α-Na, K-ATPase
The present invention provides a polypeptide of 26 amino acid residues that comprises the minimal ankyrin binding (MAB) domain. The MAB domain is responsible for the interactions between a...
|
|
|
6429259 |
Water soluble polymeric complex comprising a conducting polymer and a biopolymer
A molecular complex which comprises a biopolymer having a plurality of ionic functional groups and a conductive polymer having charges therein. The charges bind to the ionic functional groups to...
|
|
|
6372510 |
Method for removing unconventional transmissible agents from a protein solution
The present invention is drawn to method for removing unconventional transmissible agents (UCTA) from aqueous protein solution. This method involves treating the aqueous protein solution with...
|
|
|
RE37286 |
Method of cleansing a protein from multivalent metal ions bound thereto
A method is provided for cleansing a protein from multivalent metal ions bound thereto, these ions being released from the protein by exchanging the ions with monovalent metal ions, whereafter the...
|
|
|
6183121 |
Hepatitis C virus helicase crystals and coordinates that define helicase binding pockets
The invention relates to the X-ray crystal structure of the hepatitis C virus helicase domain. More specifically, the invention relates to crystallized complexes of HCV helicase and an...
|
|
|
6034221 |
High purity albumin
A process is provided for the preparation of albumin which has extremely low levels of or is essentially free of colorants, metal ions, human proteins, fragments of albumin, polymers or aggregates...
|
|
|
6022954 |
Process for the preparation of purified albumin solutions
The invention relates to a process for preparing purified albumin from a human or animal physiological solution, such as a plasma or a plasma fraction. The process includes a process of...
|
|
|
6022722 |
Renaturation of proteins
The invention relates to a method for the renaturation of denatured proteins in which they are treated with a renaturant which has on vicinal carbon atoms a hydroxyl group and at least one fluorine...
|
|
|
6001974 |
Method of separating albumin from serum by ion-exchange chromatography with membrane adsorbers
A method of separating albumin from serum by ion exchange chromatography with membrane adsorbers characterized by high productivity and yields of high purity albumin. The separation of the albumin...
|
|
|
5994507 |
Method for binding albumin and means to be used in the method
A method for binding albumin by contacting an aqueous liquid containing an albumin with an albumin-binding compound is selected from albumin-binding compounds containing the scaffold...
|
|
|
5986062 |
Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
Human serum albumin obtained by gene manipulation techniques can be purified by a combination of specified steps in which a culture supernatant obtained from a human serum albumin-producing host is...
|
|
|
RE36259 |
Preparing essentially monomeric normal human serum albumin
A composition is disclosed which comprises a solution of human serum albumin essentially free of chemicals used in processing. The preparation is also essentially free of metals such as aluminum....
|
|
|
5919907 |
Preparation and utilization of a novel sterile albumin
A method of preparing a novel, sterile, receptor rich-albumin molecule which utilizes the disinfecting properties of iodine by reacting an iodine donating material or solution with a pure...
|
|
|
5912328 |
Method for the removal of viruses from protein solutions
In order to separate viruses from protein solutions, particles of a solid phase are suspended in said protein solution. The solid phase is an adsorbent chosen from the group kieselguhr, silicic...
|
|
|
5905143 |
Purification of proteins
When proteins are purified using a protein-binding dye immobilized on a chromatographic matrix, the dye or a portion/derivative may leak into the eluant. An ion-exchange resin (e.g. Dowex-1) and a...
|
|
|
5846930 |
Therapeutic human albumin having a low aluminium binding capacity
There is described a therapeutic human albumin having a very low capacity for the absorption of aluminium, during storage in a glass receptacle, wherein the final composition of the albumin...
|
|
|
5817765 |
Purification of plasma proteins
Virus inactivating chemicals and/or detergents in an aqueous composition containing a water-soluble plasma protein are reduced by selecting a suitable combination of temperature and concentration...
|
|
|
5783423 |
Yeast strains
Reduction (preferably elimination) of the HSP150 protein in a yeast used to produce desired foreign proteins, especially human albumin, facilitates purification of the protein.
|
|
|
5763748 |
Production of heterologous protein in plants and plant cells
This invention provides for a method to produce excreted and correctly processed heterologous protein-material in a plant host. The method comprises the step of transforming a plant host using a...
|
|
|
5756680 |
Sequential separation of whey proteins and formulations thereof
A method is disclosed for the sequential separation of whey proteins using radial-flow chromatography. Different buffer systems adjusted to suitable pH and ionic strength are utilized in the...
|
|
|
5756468 |
Pharmaceutical compositions of botulinum toxin or botulinum neurotoxin and methods of preparation
Lyophilized pharmaceutical compositions containing botulinum toxin or botulinum neurotoxin and effective amounts of trehalose and methionine have a shelf life of up to 4 months or more at room...
|
|
|
5733885 |
Method of producing a virus-safe biological preparation
In a method of producing a virus-safe biological preparation by heating while preserving a least 50% of its biologic activity, a biologially compatible tenside is added to the preparation before...
|
|
|
5728553 |
High purity albumin and method of producing
A process for the preparation of albumin which has extremely low levels of or is essentially free of colorants, metal ions, human proteins, fragments of albumin, polymers or aggregates of albumin,...
|
|
|
5710253 |
Method for decoloring human serum albumin
A method for decoloring a recombinant human serum albumin by treating the albumin with a reducing agent is disclosed. Also, a method for decoloring a recombinant human serum albumin by treating the...
|
|
|
5691451 |
Method for sterilizing recombinant human serum albumin pharmaceutical preparation
A recombinant human serum albumin (rHSA) pharmaceutical preparation is sterilized by subjecting a pharmaceutical preparation of rHSA obtained by gene manipulation techniques packed in a container...
|
|
|
5677424 |
Method for purifying an aqueous solution of raw albumin
Method for purifying an aqueous solution of raw albumin wherein contaminant proteins are bound by chromatography to a stationary solid phase, preferably a particulate phase, the purified albumin...
|
|
|
5658725 |
Acylated protein aggregates and their use in suppressing interference in immunoassays
Subject matter of the invention are protein-containing interference-reducing agents for immunoassays consisting of protein aggregates that are acylated with --CO--R groups, wherein R is a branched...
|
|
|
5656729 |
Method for highly purifying human serum albumin
A method for highly purifying human serum albumin (HSA), which comprises bringing a fraction containing HSA produced by genetic engineering into contact with a chelating chromatography carrier...
|
|
|
5633349 |
Method of inactivating prions (slow viruses) conventional viruses and other infections agents in biological material
A method for the inactivation of prions, viruses and other infectious agents, which might be present in a biological raw material (e.g. plasma for the preparation of albumin), leaving the desired...
|
|
|
5616691 |
Process for producing albumin preparation
The process for producing the albumin preparation of the present invention comprises treating an aqueous albumin solution with an anion exchanger and a cation exchanger and subjecting the solution...
|
|
|
5612197 |
Process for producing recombinant human serum albumin
A process for producing recombinant human serum albumin is disclosed, which comprises culturing a human serum albumin-producing host, prepared by gene manipulation techniques in a medium that...
|
|
|
5612196 |
Human serun albumin, preparation and use
The present invention relates to a preparation of serum-human albumin having a colorimetry index lower than 0.2 resulting from the expression, in a eukaryotic or prokaryotic host, of an exogenous...
|
|
|
5585466 |
Crystals of serum albumin for use in genetic engineering and rational drug design
Serum albumin crystal forms have been produced which exhibit superior x-ray diffraction quality. The crystals are produced from both recombinant and wild-type human serum albumin, canine, and...
|