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9023991 Albumin-amyloid peptide conjugates and uses thereof  
The invention provides conjugates comprising albumin and a peptide derived from the C-terminal region of amyloid beta peptide, as well as uses thereof for the treatment of diseases characterized...
9023990 Method for isolating and purifying recombinant human serum albumin from transgenic rice grain  
A method for separating and purifying recombinant human serum albumin (rHSA) from transgenic rice grain, sequentially comprising the steps of: 1) subjecting crude extract of rHSA to cation...
9012519 Compositions and methods of delivery of pharmacological agents  
The present invention relates to a pharmaceutical composition comprising a pharmaceutical agent and a pharmaceutically acceptable carrier, which carrier comprises a protein, for example, human...
9012518 Compositions and methods of delivery of pharmacological agents  
The present invention relates to a pharmaceutical composition comprising a pharmaceutical agent and a pharmaceutically acceptable carrier, which carrier comprises a protein, for example, human...
8980826 Method of treating chronic obstructive pulmonary disease  
The present invention relates to a method of promoting bronchodilation by administration of streptolysin O to a subject in need thereof.
8901017 Formaldehyde-free proteinaceous binder compositions  
Binder compositions are described, where the compositions include a protein, a first crosslinking compound that includes a carbohydrate, and a second crosslinking compound that includes two or...
8883735 Low density lipoprotein-related protein 6 (LRP6)-half life extender constructs  
The present invention relates to LRP6 constructs that bind to LRP6 receptor. The LRP6 constructs comprise at least one LRP6 binding moiety and a half-life extender molecule such that the LRP6...
8877711 Octanoate-reduced human albumin  
A method is described that improves the transport properties of albumin produced on an industrial scale, wherein the albumin is mixed, during the production process, with substances that saturate...
8865647 Pharmaceutical solution of non covalently bound albumin and acylated insulin  
If albumin is added to a pharmaceutical formulation containing acylated insulin described in WO 2009/022005 and WO 2009/022013, the acylated insulin can be kept in solution after subcutaneous...
8858917 Methods for limiting spread of pulmonary infections  
Formulations have been developed for pulmonary delivery to treat or reduce the infectivity of diseases such as vital infections, especially tuberculosis, SARS, influenza and respiratory synticial...
8846771 Compositions and methods of delivery of pharmacological agents  
The present invention relates to a pharmaceutical composition comprising a pharmaceutical agent and a pharmaceutically acceptable carrier, which carrier comprises a protein, for example, human...
8765915 Modified coagulation factor VIIa with extended half-life  
The present invention relates to the fields of Factor VII (FVII) and Factor VIIa (FVIIa) albumin linked polypeptides. More specifically, the invention relates to cDNA sequences coding for human...
8754194 Modified coagulation factors with prolonged in vivo half-life  
The present invention relates to nucleic acid sequences coding for modified coagulation factors, preferably coagulation factor VIII, and their derivatives; recombinant expression vectors...
8748380 Albumin variants  
The present invention relates to variants of a parent albumin having altered plasma half-life compared with the parent albumin. The present invention also relates to fusion polypeptides and...
8741832 Pegylated albumin and uses thereof  
The present invention provides PEGylated hemoglobins and PEGylated albumins comprising polyethylene glycol (PEG) conjugated to hemoglobin or to albumin, wherein the PEG is a maleimide PEG, an...
8741662 Albumin-bound protein/peptide complex as a biomarker for disease  
Methods and kits for diagnosis and prognosis using biomarkers comprising albumin-bound protein/peptide complex (ABPPC).
8715718 Extracellular matrix production from nanoscale substrate  
Compositions, methods, and kits for repair and production of extracellular matrix are provided. In the broad aspect, the composition comprises a ligand of α5β1 integrin attached to a surface of a...
8685923 Fibrillar albumin for use in inhibiting cancer growth  
A method for inhibiting survival of cancer cells in a subject is disclosed. The method comprises administering to a subject in need thereof a therapeutically effective amount of fibrillar albumin....
8686225 Monocot seed product comprising a human blood protein  
The invention is directed to blood proteins produced in monocot seeds and isolated therefrom for use in therapeutic compositions, as well as to methods of making these isolated blood proteins and...
8680315 Prodrugs and drug-macromolecule conjugates having controlled drug release rates  
The present invention provides methods and compositions that permit controlled and prolonged drug release in vivo. The compounds are either prodrugs with tunable rates of release, or conjugates of...
8575104 Factor VIII, von willebrand factor or complexes thereof with prolonged in vivo half-life  
The present invention relates to modified nucleic acid sequences coding for coagulation factor VIII (FVIII) and for von Willebrand factor (VWF) as well as complexes thereof and their derivatives,...
8574587 Selective heated extraction of albumin proteins from intact freshwater algal cells  
Methods for selective extraction and fractionation of algal proteins from an algal biomass or algal culture are disclosed. A method of selective removal of products from an algal biomass provides...
8551953 Treatment of T-cell mediated diseases  
The invention provides a method of treating T-cell mediated diseases and a method of inhibiting the activation of T-cells using certain diketopiperazines. The invention also provides methods of...
8551948 Albumin fibers and fabrics and methods of generating and using same  
Provided are method of generating a fiber from a globular protein such as albumin. Also provided are albumin fibers and fabrics and methods of using same for bonding a damaged tissue or for ex...
8546333 Albumin fibers and fabrics and methods of generating and using same  
Provided are method of generating a fiber from a globular protein such as albumin. Also provided are albumin fibers and fabrics and methods of using same for bonding a damaged tissue or for ex...
8524864 Method for producing conjugate of thyroxine and albumin  
It is an object of the present invention to provide a method for producing a conjugate of thyroxine and albumin with higher purity. The present invention provides a method for producing a...
8518869 Pharmaceutical combined preparation containing a therapeutic protein  
A pharmaceutically combined preparation can contain a therapeutic protein having SH-groups which are nitrosated and a compound containing thiol groups and having an average molecular weight of at...
8513189 Albumin fusion proteins  
The present invention encompasses albumin fusion proteins. Nucleic acid molecules encoding the albumin fusion proteins of the invention are also encompassed by the invention, as are vectors...
8486716 Method for detection of basic peptide and reagent for detection of basic peptide  
The present invention provides a method for detection of a basic peptide by mixing a sample suspected to contain the basic peptide and a reagent containing denatured albumin and detecting...
8455449 Compositions and methods for modulating γ-c-cytokine activity  
The γc-family cytokines, Interleukin-2 (IL-2), Interleukin-4 (IL-4), Interleukin-7 (IL-7), Interleukin-9 (IL-9), Interleukin-15 (IL-15), and Interleukin-21 (IL-21), are associated with important...
8431532 FZD8 extracellular domains and FZD8 extracellular domain fusion molecules and treatments using same  
Methods of treatment using Fzd8 extracellular domains (ECDs), Fzd8 ECD fusion molecules, and/or antibodies that bind Fzd8 are provided. Such methods include, but are not limited to, methods of...
8314156 Compositions and methods of delivery of pharmacological agents  
The present invention relates to a pharmaceutical composition comprising a pharmaceutical agent and a pharmaceutically acceptable carrier, which carrier comprises a protein, for example, human...
8309520 Fully synthetic albumin analog  
The present invention relates to a fully synthetic albumin analog, to a hemocompatible coating for medical devices containing the fully synthetic albumin analog, as well as to medical devices...
8252747 Tissue adhesive sealant  
A tissue adhesive sealant includes a cross-linkable protein in a solution that when combined with a cross-linking agent solution including an aldehyde and amino acid containing species reactive...
8236927 Stabilizer molecule-depleted albumin solution  
The invention concerns a method for producing an aqueous albumin solution from a starting albumin solution which contains stabilizer molecules which are capable of occupying binding sites of the...
8227207 Bioactive peptides derived from the proteins of egg white by means of enzymatic hydrolysis  
The invention relates to the production of ovoproducts containing bioactive peptides from the egg white subjected to enzymatic treatment. Said peptides have an inhibiting activity of the...
8211439 Albumin fusion proteins comprising insulin polypeptides  
The present invention encompasses albumin fusion proteins. Nucleic acid molecules encoding the albumin fusion proteins of the invention are also encompassed by the invention, as are vectors...
8183209 Treatment of T-cell mediated diseases  
The invention provides a method of treating T-cell mediated diseases and a method of inhibiting the activation of T-cells using certain diketopiperazines. The invention also provides methods of...
8168429 Method of amplifying hematopoietic stem cell and hematopoietic progenitor cell  
The present invention provides useful means in an expansion culture system for a hematopoietic cell (hematopoietic stem cell, hematopoietic progenitor cell). Specifically, the present invention...
8138229 Compositions and methods of delivery of pharmacological agents  
The present invention relates to a pharmaceutical composition comprising a pharmaceutical agent and a pharmaceutically acceptable carrier, which carrier comprises a protein, for example, human...
8129506 Modulation of the interaction of MUC1 with MUC1 ligands  
The present invention provides for chimeric proteins comprising a MUC1 extracellular (MUC1-EC) polypeptide and a carrier polypeptide that function as traps for MUC1 ligands.
8084580 Therapeutic human albumin solutions with low prekallikrein activator (PKA) activity and process for obtaining them  
The invention discloses a purified albumin solution of human origin with low prekallicrein activator (PKA) activity and stability over time characterized in that it has an antithrombin content...
8071546 Uses of pegylated albumin  
The present invention is directed to uses of PEGylated albumins which include methods of treating reduced functional capillary density, reduced blood volume, septic shock and cardiac arrhythmia in...
7993877 Process for the purification of recombinant albumin  
A process is provided for the preparation of a highly pure recombinant albumin solution having a nickel ion content of less than 100 ng per gram of albumin. The process comprises subjecting a...
7939632 Proteolytically cleavable fusion proteins with high molar specific activity  
The invention relates to therapeutic fusion proteins in which a coagulation factor is fused to a half-life enhancing polypeptide, and in which both are connected by a linker peptide that is...
7837878 Method and system for colloid exchange therapy  
The present invention relates to a method and system for using a hemofilter to treat IMRD, hepatic failure, exogenous intoxication and other conditions associated with toxins in a patient's blood....
7833521 Methods of treating using hormone-albumin fusion proteins  
Biologically active polypeptides comprising a therapeutically active polypeptide fused to human serum albumin or a variant of human serum albumin, methods for preparation, nucleotide sequences...
7803791 Method for producing albumin conjugates containing gyrase inhibitors  
The present invention is directed to a Gyrase inhibitor-protein conjugate; in particular a Gyrase inhibitor-albumin conjugate. The present invention further provides methods of the treatment of...
7799759 Albumin fusion proteins  
The present invention encompasses albumin fusion proteins. Nucleic acid molecules encoding the albumin fusion proteins of the invention are also encompassed by the invention, as are vectors...
7700732 Prekallikrein depleted plasma derived albumin fraction  
An albumin containing fraction having a reduced prekallikrein activator (PKA) content and a method of manufacturing same comprising the steps of: (a) reconstitution of paste V (Cohn...

Matches 1 - 50 out of 274 1 2 3 4 5 6 >