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7605231 |
Gelatin derivatives and high-molecular micelle comprising the derivatives
The present invention relates to a gelatin derivative having an organic compound as a graft chain and a high-molecular weight micelle containing the gelatin derivative. As the organic compound, a...
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7485323 |
Process for making a low molecular weight gelatine hydrolysate and gelatine hydrolysate compositions
The present invention provides a process to make a gelatine hydrolysate, a gelatine hydrolysate and gelatine compositions comprising gelatine hydrolysates. More specifically, the invention provides...
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7393928 |
Recombinant gelatins
The present invention relates to recombinant gelatins and compositions thereof, and methods of producing and using the same.
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7320962 |
Hemoactive compositions and methods for their manufacture and use
Dried hemoactive materials comprise both a cross-linked biologically compatible polymer and a non-cross-linked biologically compatible polymer. The cross-linked polymer is selected to form a...
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7238657 |
Cartilage/Bone inducing materials for preparation
A cartilage and bone morphogenetic repairing composition which contains a bone morphogenetic protein and a polyoxyethylene-polyoxypropylene glycol is disclosed. It is preferable that the molecular...
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7138373 |
Polysaccharide-based polymers and methods of making the same
Gels and polymers comprising a polypeptide bound to a polysaccharide are disclosed. Specific polypeptides include, but are not limited to, polypeptides that comprise glutamine or tyrosine residues....
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7129210 |
Tissue adhesive sealant
A tissue adhesive sealant includes a cross-linkable protein in a solution that when combined with a cross-linking agent solution including an aldehyde and amino acid containing species reactive...
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7098315 |
Method of preparing a collagen sponge, a device for extracting a part of a collagen foam, and an elongated collagen sponge
A method of preparing a collagen sponge comprises mixing air into a collagen gel, so as to obtain a collagen foam which is dried. From the dried product thereby obtained, collagen sponge is...
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7094580 |
Methods for producing pure perlecan and other heparan sulfate proteoglycans
A method of perlecan isolation (from the EHS tumor) which produces “clean” (i.e. substantially “pure”) perlecan is disclosed. Clean perlecan is thus produced in sufficient quantities for...
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6995242 |
Process for producing insoluble and soluble collagen protein products from poultry skins and use thereof
A method of extracting and fractionating collagen-rich proteinaceous materials and derivatives from poultry skin tissue and the development of the proteinaceous materials to collagen-based protein...
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6987001 |
Methods and compositions using stearoyl-CoA desaturase to identify triglyceride reducing therapeutic agents
The use of screening assays based on the role of human stearoyl-CoA desaturase-1 (“hSCD1”) in human diseases, disorders or conditions relating to serum levels of triglyceride, VLDL, HDL, LDL,...
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6986984 |
Use of defibrinated blood for manufacture of a hemoglobin-based oxygen carrier
Red blood cells are purified by defibrinating whole blood and then filtering the defibrinated whole blood, whereby at least a portion of a plasma component is separated from the red blood cells to...
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6911071 |
Photographic element containing acid processed gelatin
The present invention relates to an imaging member comprising poultry gelatin. In one embodiment, the poultry gelatin is located preferably in at least one layer in the upper half of said imaging...
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6903071 |
Cartilage/bone inducing materials for reparation
A cartrilage and bone morphogenetic repairing composition comprising a collagen-free aqueous solution of a polyoxyethylene-polyoxypropylene and an effective amount of a bone morphogenetic protein,...
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6831058 |
Crosslinked gelatin gel preparation containing basic fibroblast growth factor
The present invention relates to a crosslinked gelatin gel preparation containing a basic fibroblast growth factor hereinafter referred to as bFGF wherein a crosslinked gelatin gel is used as a...
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6709864 |
Adipogenic differentiation of human mesenchymal stem cells
A composition which comprises human mesenchymal stem cells which have the potential to differentiate into cells of more than one connective tissue type and a composition which induces cells from...
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6706467 |
Coating fluid for imaging element comprising solubilized collagen gelatin colloidal dispersion
An aqueous coating fluid is described comprising gelatin at a concentration of at least 1 wt % and a colloidal particle dispersed material phase at a volume fraction of at least 0.01, wherein at...
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6689870 |
Protein macromolecular dyes
Protein macromolecular dyes, A(B) b are disclosed, wherein A are protein macromolecules including natural protein macromolecules and modified natural protein macromolecules such as casein, gelatin...
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6689755 |
Method of stabilizing biologically active substances
The present invention relates to a rapid and readily reproducible process for stabilizing biologically active substances by combining the biologically active substance witha a stabilizingmixture...
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6624144 |
Matrix metalloproteinase inhibitors and down-regulators
The present invention relates to novel matrix metalloproteinase (MMP) inhibitors and down-regulators, to a process for the preparation of these inhibitors, to pharmaceutical compositions comprising...
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6503553 |
Processed dairy products
A range of products and methods are based on a creamy base of cream, artificial cream, thickened cream, cream cheese, mixtures thereof and mixtures with compatible incidental ingredients, the...
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6428978 |
Methods for the production of gelatin and full-length triple helical collagen in recombinant cells
Methods are disclosed for simplified recombinant production of fibrillar collagens. DNAs encoding fibrillar collagen monomers lacking the N propeptide, the C propeptide, or both propeptides are...
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6413742 |
Recombinant gelatin and full-length triple helical collagen
Methods are disclosed for simplified recombinant production of fibrillar collagens. DNAs encoding fibrillar collagen monomers lacking the N propeptide, the C propeptide, or both propeptides are...
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6344437 |
Medicine drink food and feed having an action of strengthening bone
The present invention is to provide a novel medicine, drink, food or feed having an action of strengthening bone. More specifically, the present invention is to provide a medicine, drink, food or...
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6284459 |
Solid support matrices with memories and combinatorial libraries therefrom
Combinations, called matrices with memories, of matrix materials that are encoded with an optically readable code are provided. The matrix materials are those that are used in as supports in solid...
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6277394 |
Collagen-polymer matrices with differential biodegradability
The current invention is a biomedical implant comprising a biomedical matrix material and a biodegradable porosifying agent. As the porosifying agent degrades in situ, an implant with an...
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6183741 |
Method for reducing insolubles in a gelatin solution
The present invention is a process for reducing gelatin insolubles which includes providing a gelatin solution and adding to the gelatin solution amylase in an amount to provide a concentration of...
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6179872 |
Biopolymer matt for use in tissue repair and reconstruction
Biopolymer matt, biopolymer matt composites, biopolymer matt compositions, and methods of preparing the matt and composite matts are described. Also described are biocompatible constructs which...
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6090915 |
Collagen or gelatin crumble composition and uses
An animal collagen or gelatin based crumble, and processes for the preparation of the particulate crumble, are useful in the preparation of collagen or gelatin based compositions. The crumble is...
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6037451 |
Method of degreasing bone for gelatin manufacture
The present invention is a process for degreasing bone for the manufacture of gelatin. A lipase solution at a concentration of greater than 0.1 ppm is added to a collagen containing material and...
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6004943 |
Protein-coated medical substrates for local delivery of genes and method of forming coatings on the substrates
This invention is directed to an article, such as a medical device, for local delivery of genes. The article comprises a substrate coated with a cross-linked protein. The invention is also directed...
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5955578 |
Polypeptide-polymer conjugates active in wound healing
A conjugate of a synthetic polypeptide containing RGD or (dR) GD and a biodegradable polymer, such as hyaluronic acid or chondroitin sulfate is disclosed. Methods of making the conjugate and using...
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5919906 |
Protease produced gelatin
The present invention describes a gelatin having a high molecular weight fraction (>250,000 Daltons) of from 0 to 25 wt %, a beta fraction (150,000-250,000 Daltons) of from 0 to 20 wt % and an...
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5908921 |
Method of manufacturing gelatin
The present invention is a process for the manufacture of gelatin which includes providing a collagen containing material and demineralizing the collagen containing material to produce ossein. The...
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5877287 |
Method for producing gelatin
In a method for producing gelatin from collagen-containing raw material, the raw material is ground and mixed with water to form a slurry; the slurry is treated with an acid and heated in order to...
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5869277 |
Method for measuring type IV collagenase
The present invention relates to the development of a modified substrate capture immunoassay useful in the detection of a neutral metalloproteinase enzyme, type IV collagenase. Capture and...
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5834232 |
Cross-linked gelatin gels and methods of making them
Enzymatically cross-linked protein gels and methods for preparing them are disclosed. The methods comprise adding a transglutaminase, such as factor XIII, to a composition of a...
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5800977 |
Hardening a hydrophilic colloid composition
A hydrophilic colloid is hardened with a vinyl-sulfone hardener in the presence of a borate compound in an amount sufficient to accelerate the rate of hardening. The borate compound is preferably a...
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5595865 |
Method of chilling a photographic emulsion
Photographic emulsions are quickly chilled to a homogeneous, particulate gel by injection of carbon dioxide coolant, while the emulsion is agitated. This process is carried out in a housing having...
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5550216 |
Gelatinase A inhibitor, and analytical reagent thereof for the determination of gelatinase A
The present invention relates to a gelatinase A inhibitor comprising as an active ingredient a peptide analogue consisting of an active minimum unit of gelatinase A inhibition obtained from APP...
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5536817 |
Type of modified gelatin and its use in a DTR material
A modified gelatin is disclosed wherein part of the free carboxyl groups is replaced by modifiers having more acid end-standing groups chosen from --SO 3 M, --OSO 3 M, --SSO 3 M, ---OPO(OH) 2 ,...
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5500415 |
Process for the preparation of spherules of active principles and emulsions containing the spherules
A process for the preparation of spherules and emulsions containing such spherules. A primary oil-in-water emulsion is formed containing particles comprising one or more active principles in oily...
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5487895 |
Method for forming controlled release polymeric substrate
A method for forming a controlled release polymeric substrate is provided by contacting a polymeric substrate with a liquid mixture containing a cross-linking agent at least partially soluble...
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5484888 |
Gelatin production
Gelatin, having high Bloom or gel strength in excess of 300, is extracted from fish, with high yield, by pre-treating collagen rich fish skins with a limewater (Ca(OH) 2 ) solution suspension with...
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5459241 |
Continuous process for the preparation of gelatin from powdered bone, and gelatin obtained
A process for the preparation of gelatin from powdered bone, which consists in subjecting the powdered bone to a first treatment with an acid solution at a temperature below ambient temperature in...
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5434249 |
Method for modulating specific activity of inteferon alpha
A method for modulating the specific activitiy of a target protein which is being purified. A controller protein is added to the target protein prior to conducting a final purification step in a...
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5412075 |
Control of methionine content in photographic grade gelatin
The method for preparing high grade gelatin with a specific methionine content and with reduced methionine variability from batch to batch and within a single extraction includes controlling the...
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5411856 |
Carbamyl-substituted bis(vinylsulfonyl) methane hardeners
Novel compounds represented by formula (I) ##STR1## wherein R 1 and R 2 represent hydrogen or alkyl, R 3 represents hydrogen, alkyl, substituted alkyl or CONR 1 R 2 , and n is 0 to 6, can be...
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5395748 |
Ballasted optical brighteners
An inexpensive, ballasted optical brightener for use in photographic elements is prepared by reacting an optical brightener of the formula ##STR1## where M is a cation; X is a group capable of...
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5391477 |
In situ modification of gelatin carboxyl groups
A photographic element comprising a modified gelatin whereby the modification results in carbamoyl groups by forming peptide bonds using fast-acting hardener. The derivatization involves initial...
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