Patents in Class 530/328

Matches 1 - 50 out of 1748

Match	Document	Document Title
1	7619059	Bimolecular optical probes Compositions, methods, and kits for detecting and monitoring post-translational modification activities, including kinase or phosphatase activities, are described. The compositions typically...
2	7618636	Antigenic meningococcal peptides WO99/36544 discloses a large number of proteins from Neisseria Meningitidis . The present invention relates to fragments of those proteins which comprise at least one antigenic determinant....
3	7618634	Neurotoxic oligomers This invention relates to methods and compositions for the treatment or alleviation of Alzheimer's disease and of other conditions related to abnormal protein aggregation. In particular, the...
4	7612168	Modified HIV peptides, antigens, compositions, immunoassay kit and a method of detecting antibodies induced by HIV The present invention comprises novel and modified peptides capable of inducing a HIV-1 specific immune response without antagonizing the cytotoxic T-cell activity in order to achieve an effective...
5	7612162	Peptide analogs capable of enhancing stimulation of a glioma-specific CTL response The invention provides a peptide derived from the interleukin-13 receptor α2, which serves as a HLA-A2-restricted cytotoxic T lymphocyte (CTL) epitope. The invention can be used as a vaccine for...
6	7611713	Inducing cellular immune responses to hepatitis B virus using peptide compositions This invention uses our knowledge of the mechanisms by which antigen is recognized by T cells to develop epitope-based vaccines directed towards HBV. More specifically, this application...
7	7611711	VEGFR-3 inhibitor materials and methods The present invention relates to the diagnosis, evaluation, and therapeutic intervention of disorders mediated by the activity of cell surface receptor VEGFR-3, which activity often is stimulated...
8	7605150	Drug therapy for Celiac Sprue Administering an effective dose of a tTGase inhibitor to a Celiac or dermatitis herpetiformis patient reduces the toxic effects of toxic gluten oligopeptides, thereby attenuating or eliminating the...
9	7605120	Antagonists of the brandykinin B1 receptor The present invention relates to certain biologically active peptides and conjugated peptides which can be used as therapeutics or prophylactics against diseases or conditions linked to B1 as the...
10	7604955	Immunoglobulin E vaccines and methods of use thereof The present invention concerns the prophylaxis or therapy of immunoglobulin E-mediated disease conditions. The present invention discloses methods for identifying peptides that induce a cytotoxic...
11	7604811	Oral-intestinal vaccines against diseases caused by enteropathic organisms using antigens encapsulated within biodegradable-biocompatible microspheres This invention is directed to oral-intestinal vaccines and their use against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres.
12	7601801	HLA-A24 binding cancer antigen peptide derived from livin The present invention provides a partial peptide consisting of 8-11 contiguous amino acids in the amino acid sequence of livin set forth in SEQ ID NO: 1, which binds to HLA-A24 antigen and is...
13	7598223	Methods for producing target cell reactive lymphocytes Methods and compositions for producing target cell reactive lymphocytes, e.g., cytolytic T-lymphocytes, in a subject are provided. In practicing the subject methods, a lymphocyte population is...
14	7598221	Synthetic HLA binding WT-1 peptide analogues and uses thereof The present invention is directed to a synthetic peptide comprising a sequence of amino acids containing at least a segment that is an analogue of a native peptide that specifically binds to HLA...
15	7595297	Method of reducing injury to mammalian cells A method of inhibiting the binding between N-methyl-D-aspartate receptors and neuronal proteins in a neuron the method comprising administering to the neuron an effective inhibiting amount of a...
16	7589063	Molecules which promote hematopoiesis Peptides, methods for the preparation thereof, medicaments containing the peptides, and their use in selected indications, such as the treatment of various forms of anemia and stroke.
17	7589058	Ghrelin analogs The invention comprises peptidyl analogs that possess agonist or antagonist ghrelin activity, along with therapeutic and non-therapeutic uses thereof.
18	7585844	Myosin light chain kinase inhibitors and methods of use Disclosed are inhibitors of myosin light chain kinase, pharmaceutical compositions and kits comprising the inhibitors and methods of use.
19	7582603	Method for treating or inhibiting intestinal inflammation Peptide antagonists of zonulin are disclosed, as well as methods for the use of the same. The peptide antagonists bind to the zonula occludens receptor, yet do not physiologically modulate the...
20	7579436	Peptide compound for measuring sulfur compound and ammonia A peptide compound for measuring sulfur compound and ammonia and measurement method and device using the compound. The method comprises contacting an analyte with a sensory device coated with the...
21	7579435	Somatostatin-dopamine chimeric analogs Disclosed is a series of somatostatin-dopamine chimeric analogs which retain both somatostatin and dopamine activity in vivo. An example is:...
22	7579320	IAP BIR domain binding compounds Disclosed is an isomer, enantiomer, diastereoisomer or tautomer of a compound represented by Formula I or II or a salt thereof, in which R 1 , R 2 , R 3 , R 100 , R 200 , R 300 , A, A 1 , BG, Q...
23	7579165	Methods for derivatizing protein or peptide with sulfonic acid groups The present invention provides a method for effectively introducing sulfonic acid groups into the N-terminus of a protein or a peptide. The method comprises a modification step to react a...
24	7576176	Neisseria meningitidis antigens and compositions The invention provides proteins from Neisseria meningitidis , including the amino acid sequences and the corresponding nucleotide sequences. The proteins are predicted to be useful antigens for...
25	7576175	Alpha-4 beta-1 integrin ligands for imaging and therapy The present invention provides α 4 β 1 integrin ligands that display high binding affinity, specificity, and stability. The ligands comprise a peptide having n independently selected amino...
26	7572883	Somatostatin-dopamine chimeric analogs Disclosed is a series of somatostatin-dopamine chimeric analogs which retain both somatostatin and dopamine activity in vivo. An example is: ...
27	7569547	Inhibiting furin with polybasic peptides Small, polybasic peptides are disclosed that are effective as furin inhibitors, e.g. hexa- to nona-peptides having L-Arg or L-Lys in most positions. Removing the peptide terminating groups can...
28	7569231	Method for stabilizing oil-based thickening gel composition The present invention relates to (1) a stabilized oil-based thickening gel composition comprising (a) an anionic surfactant having a lipopeptide structure, (b) water and/or a polyhydric alcohol...
29	7569225	Immunogenic lipopeptides comprising T-helper and B-cell epitopes The present invention provides synthetic immunogenic lipopeptide molecules comprising co-linear T-helper and B cell epitopes, and methods for their production and use in the generation of primary...
30	7566695	Multimeric apoprotein agonists The present invention provides multimeric apoprotein agonists. Pharmaceutical compositions which include a multimeric apoprotein agonist and a pharmaceutically acceptable carrier, excipient or...
31	7563864	Prolyl endopeptidase mediated destruction of T cell epitopes in whole gluten Celiac Sprue and/or dermatitis herpetiformis are treated by interfering with HLA binding of immunogenic gluten peptides. The antigenicity of gluten oligopeptides and the ill effects caused by an...
32	7560429	Orodispersible dosage forms of desmopressin acetate Good bioavailability of desmopressin can be obtained by means of an orodispersible pharmaceutical dosage form. Preferred dosage forms comprise desmopressin and an open matrix network which is an...
33	7556809	Active antiangiogenic therapy Application of oligonucleotide and polypeptide sequences of molecules of the family of the vascular permeability factor (VPF), their receptors, and co-receptors, as well as their modifications, in...
34	7553928	Use of des-Aspartate-angiotensin I as an agent for the treatment and prevention of glomerulosclerosis and renal failure The present invention relates generally to a method for the treatment and/or prophylaxis of renal-related disorders. More particularly, the present invention contemplates a method for the treatment...
35	7550558	Antimicrobial peptides and methods for identifying and using such peptides This invention relates to a method for identifying peptides having antimicrobial activity and to the antimicrobial peptides identified thereby and methods for their use.
36	7550438	Methods for production of growth-promoting proteins and peptides for kidney epithelial cells Novel growth peptides derived from protein factors having molecular weights of about 22 and 45 kDa stimulate mitogenic activity of epithelial, but not fibroblastic cells, in particular, kidney...
37	7550425	Diuretic peptide conjugates Disclosed are a variety of peptide conjugates represented by the following general formula: R 1 -Z-X-Z′-R 2
38	7547759	Induction of tumor immunity by variants of folate binding protein The present invention is directed to variants of antigens comprising folate binding protein epitopes as a composition associated with providing immunity against a tumor in an individual. The...
39	7547676	Antagonist peptides to the C5A chemotactic function of vitamin D binding protein It has been demonstrated that one of Vitamin D Binding Protein (DBP) biological functions is to enhance the chemotactic activity of C5 a and C5 a des Arg. The present invention has found that...
40	7547517	MAGE-C2 antigenic peptides and uses thereof This invention relates to isolated peptides derived from MAGE-C2, nucleic acid molecules that encode MAGE-C2 and the isolated peptides derived from MAGE-C2, expression vectors comprising the...
41	7547440	T-cell epitope peptides The T-cell epitope site on a Japanese cypress (hinoki) pollen allergen molecule has been identified by stimulating a T-cell line established from a patient suffering from Japanese cypress pollen...
42	7544774	Mimotopes and anti-mimotopes of human platelet glycoprotein Ib/IX The present invention is directed to an isolated peptide that functionally mimics a binding site for a monoclonal antibody, the monoclonal antibody recognizing an epitope within the human platelet...
43	7544772	Methods for regulating inflammatory mediators and peptides useful therein The present invention includes methods of modulating cellular secretory processes. More specifically the present invention relates to modulating or reducing the release of inflammatory mediators...
44	7544666	NAP derivatives An oligopeptide comprises formulae (I) or (II) the oligopeptide derivative thereof, and a pharmaceutical composition comprising the same are provided.
45	7541430	Peptides for use in treating obesity Novel cyclic and linear peptides of the formula R 1 —X—X 1 —X 2 —X 3 —X 4 —X 5 —X 6 —X 7 —X 8 —X 9 —X 10 —X 11 —R 2 are useful in the treatment of obesity are provided.
46	7541429	Comparative ligand mapping from MHC positive cells The present invention relates generally to a methodology for the isolation, purification and identification of peptide ligands presented by MHC positive cells. In particular, the methodology of the...
47	7534441	Immunogenic LHRH compositions and methods relating thereto The present invention relates generally to an immunogenic LHRH composition and more particularly to an immunogenic LHRH composition comprising a LHRH C-terminal fragment of at least five amino...
48	7531516	Peptidic compounds selectively binding to P-selectin The present invention relates to compounds which bind selectively to the adhesion molecule human P-selectin, and particularly to such compounds comprising a peptide with an amino acid sequence XA x...
49	7531515	Peptides selectively lethal to malignant and transformed mammalian cells The present invention provides peptides corresponding to all or a portion of amino acid residues 12-26 of human p53 protein, which peptides are lethal to malignant or transformed cells when fused...
50	7531512	Method of use of peptide antagonists of zonulin to prevent or delay the onset of diabetes A method for preventing or delaying the onset of autoimmune diseases is disclosed.

Matches 1 - 50 out of 1748

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