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9040481 Methods for treating steatotic disease  
Methods for treating fatty liver disease, e.g., hepatic steatosis, using peptide fragments of the C-terminal end of glucagon-like peptide-1 (GLP-1), e.g., GLP-1(28-36).
9034824 Antioxidant, anti-inflammatory, anti-radiation, metal chelating compounds and uses thereof  
Potent compounds having combined antioxidant, anti-inflammatory, anti-radiation and metal chelating properties are described. Short peptides having these properties, and methods and uses of such...
9023800 Peptides for the treatment of oxidative stress related disorders  
Isolated DJ-1 related peptides are disclosed and pharmaceutical compositions comprising same for treating oxidative stress-related disorder.
9023987 Cell-permeable peptide  
The present invention relates to a novel human-derived cell permeable peptide-bioactive peptide conjugate and the use thereof. According to the present invention, cationic cell permeable peptides...
9018173 Materials and methods for suppressing inflammatory and neuropathic pain  
N-type voltage-gated calcium channels (CaV2.2) are critical mediators of neurotransmitter release and are thought to be involved with transmission of nociception. The use of conventional CaV2.2...
9017656 Small cationic antimicrobial peptides  
The present invention relates generally to peptides and more specifically to antimicrobial and immunomodulatory host defense peptides.
9018350 Phoenixin peptides  
Human phoenixin peptides, analogs and mimetics useful in production of anti-phoenixin antibodies, diagnostic screening and assays, and in modulating cellular concentration of cAMP, and treatment...
9018351 Peptide aptamers against tenascin C  
The present invention relates to an anti-tenascin C peptide aptamer having a specific amino acid sequence and a diagnosis kit comprising it. The anti-tenascin C peptide aptamer of the instant...
9017957 Prostasin partial peptide and anti-prostasin antibody  
An object of the present invention is to provide an antibody that can be stably supplied and can react with prostasin under non-denaturation and denaturation conditions, and an antigen peptide for...
9012603 Peptides that block the binding of IgG to FcRn  
The invention relates to peptides which bind to human FcRn and inhibit binding of the Fc portion of an IgG to an FcRn, thereby modulating serum IgG levels. The disclosed compositions and methods...
9012403 Peptides as active agents to stabilize biological barriers  
The present invention relates to compounds, in particular peptides which are capable of stabilizing barrier functions of epithelium and endothelium. The peptides and other compounds of the present...
9005627 Contiguous overlapping peptides for treatment of ragweed pollen allergy  
Contiguous overlapping peptides (COPs) for the treatment of allergic patients by Specific Immunotherapy (SIT) are provided from the sequence of the major allergen of ragweed pollen Amb a 1. Such...
9006393 Molecular constructs and uses thereof in ribosomal translational events  
Stalled ribosome:nascent molecule of interest complexes and methods of using same are provided. Plasmids, particularly DNA plasmids, comprising a stall segment are also disclosed. The methods...
9006394 Peptide-presenting surfaces for long-term culture of pluripotent cells  
The present invention relates to methods of growing and maintaining pluripotent cells on an insoluble substrate that presents a peptide that binds to glycosaminoglycans, such as heparin....
9006390 MEK ligands and polynucleotides encoding MEK ligands  
The invention relates to kinase ligands and polyligands. In particular, the invention relates to ligands, homopolyligands, and heteropolyligands that modulate MEK activity. The ligands and...
8999925 Arenavirus inhibiting peptides and uses therefor  
The present invention describes peptides which inhibit fusion of an arenavirus (e.g., Pichinde virus; PICV) with a host cell membrane. The arenavirus inhibiting (AVI) peptides described herein...
8999349 HMGB1-derived peptides enhance immune response to antigens  
The invention provides an immunostimulatory peptide containing the amino acid sequence SAFFLFCSE and uses thereof. The invention also provides an immunostimulatory peptide containing the amino...
8999919 Compositions and methods for inhibiting the interaction between CFTR and CAL  
The present invention features compositions and methods for increasing the cell surface expression of degradation-prone CFTR proteins and preventing or treating cystic fibrosis. The invention...
8999937 Glucocorticoid induced leucine zipper mimetics as therapeutic agents in multiple sclerosis  
Polypeptide compositions that mimic the activity of glucocorticoid induced leucine zipper (GILZ) on the immune system are described. Also described is a method of treating multiple sclerosis using...
8999346 Immunogenic control of tumours and tumour cells  
The present invention relates to the use of immunogenic peptides comprising a T-cell epitope derived from a tumour-associated antigen and a redox motif such as C-(X)2-[CST] or [CST]-(X)2-C in the...
9000124 Peptides that specifically bind HGF receptor (cMet) and uses thereof  
A polypeptide or multimeric polypeptide construct having the ability to bind to cMet or a complex comprising cMet and HGF, and methods for use are disclosed.
8999939 Hair treatment agents having low-dose oligopeptides  
A hair treatment agent having advantageous properties is provided. The hair treatment agent contains, based on weight of the agent, 0.00001 to ≦0.05% by weight of at least one oligopeptide having...
8993720 Methods for the treatment of X-linked hypophosphatemia and related disorders  
The disclosure provides methods of treating X-linked hypophosphatemia, related bone demineralization and renal phosphate wasting disorders in a mammalian subject. The methods comprise...
8987377 Poly(amide) polymers for the delivery of oligonucleotides  
The present invention provides poly(amide) polymers, polyconjugates, compositions and methods for the delivery of oligonucleotides for therapeutic purposes.
8986700 Immunogenic lipopeptides comprising T-helper and cytotoxic T-lymphocyte (CTL) epitopes  
The present invention provides synthetic immunogenic lipopeptide molecules comprising co-linear T-helper and CTL epitopes, and methods for their production and use in the generation of primary and...
8987211 Therapeutic peptides and use thereof against huntington's disease  
Fusion proteins that contain the fusion of (i) a peptide of less than 100 amino acids comprising a first amino acid sequence comprising AASSG (SEQ ID NO: 1) and a second amino acid sequence...
8986655 Compositions, devices, and methods related to prostate-specific membrane antigen  
PSMA ligands, compositions, and methods therefore are disclosed where the ligand is a peptide having the sequence X1X2CVEVX3QNSCX4X5 where X1-X5 are independently a natural or non-natural amino...
8986712 Peptides derived from HIV-1 gp41 transmembrane domain for t-immunomodulation  
The present invention relates to peptides, derivatives and analogs comprising an amino acid sequence derived from the transmembrane domain of HIV gp41 protein, pharmaceutical compositions...
8981052 JNK inhibitor molecules  
JNK inhibitor molecules are described. In addition, methods for raising antibodies against such JNK inhibitor molecules are disclosed. These antibodies and cells producing these antibodies are...
8981046 Synthetic cell platforms and methods of use thereof  
The present invention provides synthetic cell platforms. The synthetic cell platforms can be used for culturing cells in vitro. The synthetic cell platforms can also be implanted together with...
8980843 Leptin agonist and methods of use  
Peptides are provided having leptin receptor agonist activity. The peptides are useful for treating obesity, type II diabetes, appetite control after bariatric surgery, insulin resistance,...
8975384 Tag peptide and use thereof  
The present invention provides a tag peptide comprising an amino acid sequence represented by the following formula (I): X1-Tyr-X2-Gly-Gln-X3 (I) (wherein X1, X2 and X3 are the same or different...
8975370 Inhibitor proteins of a protease and use thereof  
The present invention relates to a chimeric inhibitor protein of a protease comprising an inhibiting polypeptidic sequence and at least one polypeptidic sequence of a substrate-enzyme interaction...
8975371 Melanoma antigen peptide and uses thereof  
The present invention relates to novel melanoma antigen peptides and specific T lymphocytes directed to said peptides and the use thereof for treating melanoma.
8969252 Peptide mediated synthesis of metallic and magnetic materials  
The present invention includes methods for producing magnetic nanocrystals by using a biological molecule that has been modified to possess an amino acid oligomer that is capable of specific...
8969296 TGFP-CAP peptide and its uses  
The present invention relates to a GFP-CAP peptide having an amino acid sequence derived from TGF-β1 (transforming growth factor-β1) and a cell adhesion sequence, wherein the amino acid sequence...
8961928 Ligand and metal complex having the same  
A ligand and a metal complex having the ligand are provided. The ligand and a paramagnetic metal ion form a metal complex with high stability, high relaxivity and high biocompatibility. The metal...
8961989 Methods for producing an immune response to tuberculosis  
Methods for producing an immune response to Mycobacterium tuberculosis (Mtb) are disclosed herein. In several examples, the immune response is a protective immune response. In additional...
8962565 Peptides involved in the SCF c-Kit signaling pathway and compositions comprising same  
Peptide compounds of general formula (I) R1-(AA)n-X1—X2—X3-Asp-Leu-Lys-Lys-X4—X5-(AA)p-R2, cosmetic or pharmaceutical compositions comprising at least one peptide compound of general formula (I)...
8957030 Methods for preventing or treating mitochondrial permeability transition  
The invention provides a method of reducing or preventing mitochondrial permeability transitioning. The method comprises administering an effective amount of an aromatic-cationic peptide having at...
8956869 Peptide inhibiting differentiation of hematopoietic stem cells or hematopoietic precursor cells and use of same  
The present invention provides a novel peptide that can be effectively used to produce or grow tissue-specific stem cells or tissue-specific progenitor cells in vitro. The peptide of the invention...
8957185 MUC-1 cytoplasmic domain peptides as inhibitors of cancer  
Peptides from the MUC1 cytoplasmic domain and methods of use therefor are described. These peptides can inhibit MUC1 oligomerization, thereby preventing tumor cell growth, inducing tumor cell...
8957022 Multimeric tie 2 agonists and uses thereof in stimulating angiogenesis  
The present invention provides a multimeric form of a Tie 2 binding peptide monomer, wherein the multimeric form has Tie 2 agonist activity. The multimeric form, preferably a tetramer, stimulates...
8951974 Self-assembling peptide and peptide gel with high strength  
Provide are a peptide gel with practically sufficient mechanical strength and a self-assembling peptide capable of forming the peptide gel. The self-assembling peptide is formed of the following...
8952129 Method of treating degenerative diseases  
Agonists of a non-proteolytically activated receptor can be used in methods for treating a disease or disorder in a subject. The methods comprise administering to the subject a therapeutically...
8951963 Active cores of peptide triazole HIV-1 entry inhibitors  
The invention provides a peptide triazole conjugate and derivatives thereof, and methods of its use. The invention also provides an antibody to the peptide triazole conjugate. The invention...
8951975 ECT2 peptides and vaccines including the same  
Isolated peptides derived from SEQ ID NO: 42 and fragments thereof that bind to an HLA antigen and induce cytotoxic T lymphocytes (CTL) and thus are suitable for use in the context of cancer...
8952127 Peptoids useful for catalyzing the mineralization of calcium carbonate  
The present invention provides for a bio-mimetic polymer capable of catalyzing CO2 into a carbonate.
8946150 Polypeptides that bound to IL-23 receptor and inhibit binding of IL-23 and cell signaling thereof  
The present invention relates to novel polypeptides that bind to IL-23 receptor and inhibit the binding of IL-23 to its corresponding receptor and cell signaling thereof. The novel polypeptides of...
8946383 Obtaining cocoa extracts rich in bioactive peptides with ACE and PEP enzyme inhibitory activity  
The present invention relates to obtaining bioactive peptides from plant raw materials, specifically cocoa extracts, by means of enzyme treatment. Said biopeptides have angiotensin converting...