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7361133 |
Methods of detection utilizing modified bacteriophage
Viruses expressing ligands on their surfaces are used as a detection means for the related polypeptide which binds the ligand. Multiple copies of the ligand can be expressed on the viral surface....
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7361637 |
Hypotensors
There are provided a method for selection of a substance which is capable of controlling activation of prorenin where an adjusting ability of the activation of prorenin by protein-protein...
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7361730 |
Surface localized colligin/Hsp47 in carcinoma cells
This invention relates, e.g., to colligin/Hsp47 molecules which are expressed on the surface of carcinoma cells and to the use of such expressed molecules as targets for, e.g., therapeutic agents...
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7361642 |
Canine specific growth hormone releasing hormone
A composition and a method of increasing growth hormone (“GH”) values in a canine or dog, and more specifically, a canine- or dog-specific growth hormone releasing hormone (“dGHRH”), or...
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7361638 |
Pharmaceutical combination for the treatment of tissue damage owing to an arterial irrigation defect
This invention relates to a medicine for humans, and particularly to a pharmaceutical combination comprising Epidermal Growth Factor (EGF) and Growth Hormone secretagogue hexapeptide (GHRP) for use...
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7361733 |
Compositions and methods for the therapy and diagnosis of inflammatory bowel disease
Compositions and methods for the therapy and diagnosis of Inflammatory Bowel Disease (IBD), including Crohn's Disease and Ulcerative Colitis, are disclosed. Illustrative compositions comprise one...
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7358340 |
PRO19563 antibodies
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid...
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7358329 |
Antagonists to chaperonin 10
Antibodies raised against recombinant or synthetic cpn10 are disclosed. The cpn10 has the sequence GSMAGQAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQ...
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7358330 |
Immunoregulatory compositions
The invention relates to compounds exhibiting immunoregulatory activity as determined by measuring the compound's ability to modulate production of NO by a cell. Preferred compounds include or...
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7358041 |
Antibodies to magmas and uses thereof
The present invention relates to isolated and purified Magmas protein, isolated and purified nucleic acids encoding Magmas protein, and antibodies to Magmas protein, which interacts with...
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7357932 |
Surface protein of Neisseria bacteria
Present invention provides a monoclonal antibody binding to Neisseria bacteria and its target antigen Ag473, which include the sequences of its polynucleotide and its amino acid, wherein the ...
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7358228 |
Methods of treating pain using neurotrophic factors
The invention relates to neublastin neurotrophic factor polypeptides, nucleic acids encoding neublastin polypeptides, and antibodies that bind specifically to neublastin polypeptides, as well as...
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7358096 |
Immobilisation of proteins
The immobilization of proteins at solid surfaces facilitated by incorporation of a polypeptide segment which is capable of adopting a folded structure is described. Materials comprising proteins so...
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7358076 |
Sublancin lantibiotic produced by Bacillus subtilis 168
An antimicrobial peptide produced by Bacillus subtilis 168 was isolated and characterized and named sublancin 168. The invention includes DNA encoding for the sublancin 168 peptides and peptides...
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7354903 |
Cosmetic compositions containing short bioactive peptides
Short bioactive peptides containing phenylalanine, leucine, alanine, and lysine residues are disclosed. The peptides can be used in antibacterial, antifungal, anticancer, and other biological...
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7354992 |
Isolated nucleic acid molecules encoding cancer associated antigens, the antigens per se, and uses thereof
The invention relates to newly identified cancer associated antigens. It has been discovered that each of these molecules provokes antibodies when expressed by a subject. The ramifications of this...
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7354999 |
PRO1481 polypeptides
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid...
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7355016 |
Methods for detection of mycobacteria
Nucleic acid encoding four novel immunodeterminant protein antigens of M. bovis BCG, which is a vaccine strain for tuberculosis, have been isolated. These genes were isolated as immunoreactive...
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7354993 |
Insecticidal polypeptides and methods of use thereof
The invention relates to isolated insecticidal polypeptides expressed in the venom gland of spiders of the genera Atrax and Hadronyche have been described. Methods of treating insects, insect...
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7354908 |
Materials and methods for prevention and treatment of RNA viral diseases
The subject invention concerns a method of inhibiting an RNA virus infection within a patient by increasing the amount of 2-5 oligoadenylate synthetase (2-5 AS) activity within the patient....
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7354995 |
Magnetic substance-biosubstance complex structure, peptide fragment capable of linking to magnetic substance and gene therefor, and process for producing the complex structure
A magnetic substance-biosubstance complex structure comprises a magnetic substance-containing carrier and a bio-substance immobilized on the carrier, the biosubstance being immobilized through a...
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7355005 |
Lymphocyte surface receptor that binds CAML and methods of use thereof
A novel lymphocyte receptor protein, its DNA sequence, and its role in the calcium activation pathway is described. The protein, or genetically engineered constructs encoding it, is shown to...
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7354735 |
Nucleic acid encoding fluorescent protein constructs and methods for detecting apoptosis
Isolated nucleic acids encoding a fluorescent protein construct that detect apoptosis are disclosed. The isolated nucleic acids contain a donor-acceptor pair of green fluorescent proteins and a...
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7354898 |
Identification of novel factors that block programmed cell death or apoptosis by targeting JNK
Methods and compositions for modulating apoptosis by acting on the c-Jun-N-terminal kinase (JNK) pathway and assays for the isolation of agents capable of modulating apoptosis, including modulators...
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7354991 |
Peptides for the diagnosis of schizophrenia
Short peptides are provided, which bind to a body fluid sample obtained from a schizophrenic patient at a substantively higher level than to a body fluid sample obtained from a non-schizophrenic...
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7354722 |
Modulators of Smurf and BMP/TGFβ signaling pathways
This invention provides unique members of the Hect family of ubiquitin ligases that specifically target BMP and TGFβ/activin pathway-specific Smads. The novel ligases have been named Smurf1 and...
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7351789 |
PRO19624 polypeptides
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid...
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7351690 |
Knockout identification of target-specific sites in peptides
The invention provides methods for identification and determination of target-specific sites in peptides and proteins, including a method for determining the primary sequence of a secondary...
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7351794 |
PRO1754 polypeptides
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid...
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7351797 |
Labeled peptides, and processes and intermediates useful for their preparation
The invention provides intermediates and methods that allow for site-specific modification of peptides after synthesis. Accordingly, functional molecules can be selectively linked to a peptide to...
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7348010 |
Vaccine against cancer diseases that are associated with the her-2/neu oncogene
The present invention relates to peptides of the extracellular domain of a HER-2/neu protein, conjugates comprising said peptides linked to an immunogenic carrier, compositions thereof, nucleic...
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7348136 |
Method and device for detecting feline immunodeficiency virus
A method and device for determining a feline immunodeficiency virus infection or vaccination in an animal. The method includes contacting a biological sample from a felid with various FIV...
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7348007 |
Mage C2 antigenic peptides and uses thereof
This invention relates to isolated peptides derived from MAGE-C2, nucleic acid molecules that encode MAGE-C2 and the isolated peptides derived from MAGE-C2, expression vectors comprising the...
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7348306 |
Composition for promoting lacrimal secretion
A composition for promoting lacrimal secretion which can be used safely and effectively in the lacrimal secretion promoting therapy, not in the conventional supplemental therapy of lacrimal fluid...
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7348402 |
Antimicrobial peptide, its analogs and antimicrobial composition comprising them
Disclosed is a novel antimicrobial peptide having excellent antimicrobial activities, its analogs and an antimicrobial composition comprising them. The antimicrobial peptide alternatively comprises...
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7348399 |
Nanofabricated polypeptide multilayer films, coatings, and microcapsules
Disclosed herein are films, coatings and microcapsules comprising polypeptides. A thin film, for example, comprises a plurality of layers of polypeptides, the layers comprising alternating...
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7348405 |
PRO10274 polypeptides
The present invention is directed to PRO10013 polypeptides.
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7345142 |
Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of cardiac disease
Novel markers for cardiac disease that are both sensitive and accurate. These markers are differentially and/or specifically expressed in cardiac tissue, as opposed to other types of tissues,...
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7345146 |
PRO1271 Polypeptides
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid...
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7344870 |
3-phosphoinositide-dependent protein kinase
The present invention provides for a substantially pure human or rabbit 3-phosphoinositide-dependent protein kinase.
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7343721 |
PRO4406 polypeptide
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid...
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7345022 |
Anti-fibril peptides
Novel peptides are disclosed that may be used as inhibitors of amyloidogenesis, as suppressors of amyloid toxicity, and as therapeutic agents for amyloid-associated diseases such as Alzheimer's...
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7344724 |
UspA1 and UspA2 antigens of Moraxella catarrhalis
The present invention discloses the existence of two novel proteins UspA1 and UspA2, and their respective genes uspA1 and uspA2. Each protein encompasses a region that is conserved between the two...
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7345018 |
Method of treating side effects induced by therapeutic agents
The invention relates to agents for the prevention of organ damage, in particular of the kidneys and the inner ear, induced by the administration of aminoglycosides. Agents according to the...
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7344842 |
Prion test
The invention is related to diagnostic methods for detecting transmissible spongiform encephalopathies (TSEs) such as BSE and scrapie and related disease in humans. The invention provides use of...
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7342108 |
De novo DNA cytosine methyltransferase genes, polypeptides and uses thereof
De novo DNA cytosine methyltransferase polynucleotides and polypeptides and methods for producing said polypeptides are disclosed. Also disclosed are methods for utilizing de novo DNA cytosine...
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7342109 |
Human kinase interacting protein 2 (KIP2)-related gene variant associated with cancers
Nucleic acid and polypeptide sequences of one novel human KIP2-related gene variant (KIP2V), and the processes for producing the same are provided. Use of the nucleic acid and polypeptide sequences...
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7341995 |
Use of SARP-1 for the treatment and/or prevention of scleroderma
The invention relates to the use of SARP-1 for the preparation of a medicament for the treatment and/or prevention of scleroderma, in particular of systemic sclerosis.
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7342089 |
Cyclic peptides for treatment for cachexia
A highly selective melanocortin-4 receptor antagonist cyclic peptide of the formula
where R 1 , R 2 , R 3 , R 4a , R 4b , R 5 , R 6 , R 7 , x, y and z are as defined in the specification, and a...
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7342096 |
PRO1879 polypeptide
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid...
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