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7390497 |
Poly(ester amide) filler blends for modulation of coating properties
Provided herein is a PEA polymer blend and coatings or implantable devices formed therefrom. The PEA polymer blend is formed of a PEA polymer and a material capable of hydrogen bonding with the...
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7385004 |
Enhanced lubrication in polyolefin closure with polyolefin grafted cyclodextrin
Thermoplastic polymer compositions in a closure can comprise a polymer, a modified vinyl polymer and a slip agent or polymer lubricant said modified polymer having a moiety comprising a...
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7368502 |
Hydroxyphenyl cross-linked macromolecular network and applications thereof
A dihydroxyphenyl cross-linked macromolecular network is provided that is useful in artificial tissue and tissue engineering applications, such as artificial or synthetic cartilage. The network is...
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7365123 |
Grafted cyclodextrin
Thermoplastic polymer compositions, films, continues, closures, laminates can comprise a modified vinyl polymer said modified polymer having a moiety comprising a cyclodextrin compound. The...
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7361726 |
Poly(hydroxyalkanoate-co-ester amides) and agents for use with medical articles
Polymers containing poly(hydroxyalkanoate-co-ester amides) and agents for use with medical articles are disclosed along with methods of fabricating medical articles comprising these polymers. The...
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7348391 |
Polymeric beads for oligomer synthesis
The present invention provides solid support media for use in oligomer synthesis, methods of producing the media, and methods of using the media. In some embodiments, the processes of the invention...
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7332566 |
Biocompatible crosslinked polymers with visualization agents
Biocompatible crosslinked polymers, and methods for their preparation and use, are disclosed in which the biocompatible crosslinked polymers are formed from water soluble precursors having...
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7270808 |
Cyclodextrin-based polymers for therapeutics delivery
The present invention relates to novel compositions of therapeutic cyclodextrin containing polymeric compounds designed as a carrier for small molecule therapeutics delivery and pharmaceutical...
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7238364 |
Compliant tissue sealants
An improved barrier or drug delivery system which is highly adherent to the surface to which it is applied is disclosed, along with methods for making the barrier. In the preferred embodiment, the...
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RE39713 |
Polymerizable biodegradable polymers including carbonate or dioxanone linkages
Water-soluble macromers including at least one hydrolysable linkage formed from carbonate or dioxanone groups, at least one water-soluble polymeric block, and at least one polymerizable group, and...
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7232861 |
Enzyme-mimicking polymers
The present invention provides synthetic polymers having novel catalytic functions which mimic enzymatic reactions. The invention also provides a method for measuring glycated proteins such as...
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7163677 |
Cationic polymers having degradable crosslinks
A synthetic polymer comprises a cationic recurring unit and a crosslinking unit, wherein the crosslinking unit comprises at least a first degradable unit (preferably acid-labile) and at least a...
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7157546 |
Water-soluble polymer alkanals
The present invention is directed to alkanal derivatives of water-soluble polymers such as poly(ethylene glycol), their corresponding hydrates and acetals, and to methods for preparing and using...
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7144950 |
Conformationally flexible cationic conjugated polymers
Methods, compositions and articles of manufacture involving cationic conjugated conformationally flexible polymers are provided. A method for the synthesis of cationic water-soluble polymers with...
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7144852 |
Process for preparation of particles
The present invention is directed to a process for the preparation of polysaccharide-grafted polymer particles wherein the polysaccharide is preferably a β-1,4 linked polysaccharide, comprising...
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7101932 |
Method for the preparation of 1-benzotriazolyl carbonate esters of poly (ethylene glycol)
The invention provides a method for preparing a 1-benzotriazolylcarbonate ester of a water-soluble and non-peptidic polymer by reacting a terminal hydroxyl group of a water-soluble and non-peptidic...
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7087247 |
Polyesters, method for producing same, and depot medicaments produced from these polyesters
The invention relates to novel absorbable polyesters, produced by ring-opening polymerisation of hydroxycarboxylic acids in the presence of a polyol containing an electrolyte, in an extruder. In...
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7081139 |
Antimicrobial polyester-containing articles and process for their preparation
This invention relates to antimicrobial polyester-containing articles and methodology for the preparation of antimicrobial polyester-containing articles utilizing chitosan and chitosan-metal...
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7057019 |
Crosslinked albumin hydrogels
Materials, methods, and compositions for making crosslinked albumin hydrogels are included in the application. Embodiments include a biocompatible material of albumin crosslinked with an...
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7053150 |
Segmented polymers and their conjugates
Segmented water soluble polymers, containing a higher molecular weight segment linked to a lower molecular weight segment, are described. In one embodiment, the polymer segments are poly(ethylene...
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7041855 |
Monofunctional polyethylene glycol aldehydes
The present invention provides novel monofunctional polyethylene glycol aldehydes for the pegylation of therapeutically active proteins. The pegylated protein conjugates that are produced, retain a...
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7041730 |
Polymers and their synthesis
The invention relates to polysaccharide graft polymers useful for incorporation as benefit agents in laundry detergent and fabric treatment compositions, and their preparation. The invention also...
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7034127 |
Hydrophilic biopolymer-drug conjugates, their preparation and use
Disclosed are methods of conjugating biologically active substances, particularly, alpha-interferon, with a hyaluronan or a mixture of a hyaluronan with at least one other hydrophilic polymer...
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7030187 |
Cellulose copolymers that modify fibers and surfaces and methods of making same
Cellulosic polymers, copolymers and grafts, are disclosed that adhere to fibers and surfaces during an aqueous treatment process. The cellulosic polymers having grafts and/or co-blocks are prepared...
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7026379 |
Copolymer resin composition and production process thereof
A copolymer resin composition provided by the process of the present invention is of considerable strength and moldability and is produced by polymerization of a monosaccharide or a polysaccharide...
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7026277 |
Fabric care composition
The present invention is directed to a process for the preparation of polysaccharide grafted latex particles wherein the polysaccharide has β-1,4 linkages, wherein the process comprises core/shell...
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7019073 |
Method for preparing cyclodextrin-polyolefin blends and products made therefrom
The present invention discloses a method of dispersing cyclodextrins into a base polymer. The method of the invention comprises reacting grafted microfine polymer powder with a cyclodextrin to form...
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7009034 |
Biocompatible crosslinked polymers
Biocompatible crosslinked polymers, and methods for their preparation and use, are disclosed in which the biocompatible crosslinked polymers are formed from water soluble precursors having...
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7008476 |
Modified alginic acid of alginic acid derivatives and thermosetting anti-reflective compositions thereof
Modified alginic acid or alginic acid derivatives and anti-reflective coatings based on thereon are described.
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6979464 |
Reversible geling co-polymer and method of making
The present invention is a thereapeutic agent carrier having a thermally reversible gel or geling copolymer that is a linear random copolymer of an [meth-]acrylamide derivative and a hydrophilic...
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6974856 |
Block copolymers having polymer segment derived from oxazoline
Disclosed are block copolymers represented by the following general formula (I)
wherein AI represents a hydroxyl group or an organic residue derived from an anionic polymerization initiator, R...
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6958429 |
Water-absorbing polymers with supramolecular hollow molecules, method for producing them and use of the same
The invention relates to absorbent polymers based on optionally partially neutralised, monoethylenically unsaturated, acid group-carrying monomers. The surfaces of said polymers are...
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6953850 |
Protecting groups for carbohydrate synthesis
The invention provides collections of orthogonally-protected monosaccharides as universal building blocks for the synthesis of glycoconjugates of non-carbohydrate molecules, neo-glycoconjugates and...
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6908963 |
Thioester polymer derivatives and method of modifying the N-terminus of a polypeptide therewith
The invention provides reagents and methods for conjugating polymers specifically to the α-amine of polypeptides in high yield. The invention provides monofunctional, bifunctional, and...
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6908955 |
Oligomeric dispersant
A composition that is a reaction product of two or three moieties. The first moiety (A) is a nonpolymeric, multi-functional moiety or combination of mono- or multifunctional moieties that adsorbs...
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6887974 |
Crosslinking agents and methods of use
Polymeric crosslinking agents are disclosed that have an inert water soluble polymeric component, biodegradable components, functional components reactive with chemical groups on a protein, for...
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6884842 |
Molecular compounds having complementary surfaces to targets
Synthetic polymer complements (SPCs) are provided, as well as methods for their synthesis and use. The SPCs may have surfaces that include functional groups that are complementary to surface sites...
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6828412 |
Degradable polymers
A polymer comprising: a polymeric backbone comprising at least one unit having the structure (I), wherein R-R 4 comprise groups selected from the group consisting of H, C 1 -C 12 alkyl, C 6 -C 18...
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6825341 |
Process for preparing functionalized polyalkyleneimines, compositions containing them and uses thereof
The present invention relates to a process for preparing functionalized polyalkyleneimines which are useful for formulating nucleic acids intended to be transfected into cells. This process...
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6824766 |
Biodegradable high molecular weight polymeric linkers and their conjugates
The present invention includes polymeric transport systems corresponding to the formula: wherein: R 31 is a linear or branched polymer residue; Y 10 and Y 11 are independently O, S, or NR 40...
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6774180 |
Synthesis of high molecular weight non-peptidic polymer derivatives
High molecular weight derivatives of activated poly(ethylene glycol) and the like polymers are prepared in high purity by conjugating a large PEG molecule to a small PEG molecule. Most of the...
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6764992 |
Soil release polymers and laundry detergent compositions containing them
Anionic, hydrophobic polysaccharides useful as soil release agents in detergent compositions are graft copolymers of a polysaccharide having anionic substituents with an ethylenically unsaturated...
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6762281 |
Process for preparing peptide derivatized oligomeric compounds
Methods of preparing peptide linked oligomeric compounds are provided. The method is useful for preparing larger scale amounts of peptide linked oligomeric compounds. More particularly, the...
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6740635 |
Antiviral linear polymers
An antiviral compound comprises a linear non-carbohydrate polymer having a plurality of side chain groups, wherein at least one of the side chain groups has an anionic- or cationic-containing...
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6730735 |
Conjugate of polyethylene glycol and chitosan
PEG-chitosan conjugates comprising chitosan and polyethylene glycol moieties or derivatives thereof which are bonded together and their use in medicine is described. In one embodiment, the...
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6723843 |
Oligosaccharide synthesis
The invention provides a system for solid-phase synthesis of oligosaccharides, based on the discovery that a 2-substituted-1,3-dioxocycloalkyl linker group of general formula (I) can be used to...
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6723831 |
Neoglycoproteins
Polyamide conjugates comprising either (a) a xenoantigenic group; or (b) a biologically active group and a macromolecular, macro- or microscopic entity; bound to a polyamide backbone, processes for...
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6703444 |
Process for cross-linking hyaluronic acid to polymers
The present invention relates to a process for the production of hyaluronic acid (HA) derivatives. In particular, the process relates to multiple cross-linked hyaluronic acid derivatives, to navel...
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6667366 |
Chemical modification of the surface of natural fibers
The present invention relates to polymer-grafted natural fiber used for the preparation of composite materials. The invention relates in particular to a process for making such polymer-grafted...
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6660804 |
Cyclodextrin polymers and/or cyclodextrin derivatives with complexing properties and ion-exchange properties and method for the production thereof
The present invention concerns a process for preparing copolymers of cyclodextrin(s) and/or cyclodextrin derivative(s), characterized by the following operations: (a) preparing a solid state...
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