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8158720 |
Crosslinkable polymer compositions and associated methods
Crosslinkable polymer compositions are provided that may be useful for, among other things, reducing, stopping, or diverting the flow of fluids in subterranean formations. The crosslinkable polymer...
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8153725 |
Supports for oligomer synthesis
Universal linkers, their facile processes of manufacture and methods of using the same are provided.
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8137688 |
Hydroxyphenyl cross-linked macromolecular network and applications thereof
A synthetic nucleus pulposus is provided that is useful in treatment of degenerative disc disease, augmentation of a degenerate disc, and alleviation of back pain. In an embodiment the synthetic...
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8138265 |
Hydroxyphenyl cross-linked macromolecular network and applications thereof
A dihydroxyphenyl cross-linked macromolecular network is provided that is useful in artificial tissue and tissue engineering applications, particularly to provide a synthetic macromolecular network...
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8129449 |
Crosslinking systems for hydroxyl polymers
Crosslinking systems suitable for use in a polymer melt composition wherein the polymer melt composition comprises a hydroxyl polymer; polymeric structures made from such polymer melt compositions;...
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8124128 |
Amphiphilic block copolymers and nano particles comprising the same
An amphiphilic block copolymer. The amphiphilic block copolymer includes one or more hydrophilic polymers, one or more hydrophobic polymer, and one or more zwitterions. The invention also provides...
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8105391 |
Merhods of treatment with devices having a coating containing pegylated hyaluronic acid and a pegylated non-hyaluronic acid polymer
Provided herein are a method, which comprises implanting in a patient an implantable device comprising a coating that includes a PEGylated hyaluronic acid and a PEGylated non-hyaluronic acid...
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8088843 |
Crosslinking systems for hydroxyl polymers
Crosslinking systems suitable for use in a polymer melt composition wherein the polymer melt composition comprises a hydroxyl polymer; polymeric structures made from such polymer melt compositions;...
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8080260 |
Molecular enhancement of extracellular matrix and methods of use
A composition comprising a human- or animal-derived extracellular matrix and a macromolecular network which is prepared ex vivo is provided that is useful in the repair of a tissue injury,...
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8076412 |
Water-soluble polymer alkanals
The present invention is directed to alkanal derivatives of water-soluble polymers such as poly(ethylene glycol), their corresponding hydrates and acetals, and to methods for preparing and using...
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8071678 |
Thioester-terminated water soluble polymers and method of modifying the N-terminus of a polypeptide therewith
The invention provides reagents and methods for conjugating a polymer specifically to the α-amine of a polypeptide. The invention provides monofunctional, bifunctional, and multifunctional PEGs ...
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8058344 |
Glycodendrimers having biological activity
The present invention relates to new anionic glycodendrimers having new biological activity, processes for preparing them and their use in medicine including veterinary medicine.
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8052990 |
Biocompatible crosslinked gel
The invention relates to a method for producing a biocompatible crosslinked gel consisting in crosslinking a determined quantity of at least one type of liquid biocompatible polymer by adding a...
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8021350 |
Hydroxyphenyl cross-linked macromolecular network and applications thereof
A dihydroxyphenyl cross-linked macromolecular network is provided that is useful in artificial tissue and tissue engineering applications, particularly to provide a synthetic macromolecular network...
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8008005 |
Method for the synthesis of DNA sequences
A method is disclosed for the direct synthesis of double stranded DNA molecules of a variety of sizes and with any desired sequence. The DNA molecule to be synthesis is logically broken up into...
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8007911 |
Material for room temperature curable solvent-borne overcoating material,coating material using same and coating film
To provide a coating material for a room temperature curable solvent-borne overcoating material having chipping resistance and not allowing occurrence of cracks, and a room temperature curable...
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8003089 |
Y shape branched hydrophilic polymer derivatives, their preparation methods, conjugates of the derivatives and drug molecules, and pharmaceutical compositions comprising the conjugates
The present invention relates to Y-shape branched PEG derivatives of formulae (I) to (IV). The present invention also relates to conjugates of these Y-shape derivatives and drug molecules,...
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7985874 |
Polymer particle
A support comprising functional groups supported therein that specifically react with an aldehyde group of a sugar chain, and a polymer particle and a glycochip to which the support is applied, and...
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7981943 |
Material comprising polyrotaxane and polymer and process for producing the same
A material which comprises a polyrotaxane and a polymer and is crosslinked by irradiation with light. In the material, which comprises a first polyrotaxane and a polymer, the first polyrotaxane...
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7977427 |
Method involving 1-benzotriazolyl carbonate esters of polymers
The invention provides a method comprising the steps of (i) reacting a water-soluble and non-peptidic polymer having two or more terminal hydroxyl groups with di(1-benzotriazolyl)carbonate to form...
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H002257 |
Microtags for detection and identification of materials
A customized microtag identifier has a custom synthesized polynucleic acid having a known sequence of bases, a recovery compound, and a protective coat; effective to identify said custom...
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7897684 |
Conjugated polymers suitable for strand-specific polynucleotide detection in homogeneous and solid state assays
The invention further relates to polycationic multichromophores, which may be conjugated polymers, and methods, articles and compositions employing them as described herein. In some aspects, the...
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7872072 |
Branched polymers and their conjugates
The present invention is directed to branched reactive water-soluble polymers comprising at least two polymer arms, such as poly(ethylene glycol), attached to a central aliphatic hydrocarbon core...
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7863406 |
Unsaturated poly(ester-amide) biomaterials
Biodegradable poly(ester-amides) are synthesized from amino acids, diols and dicarboxylic acids where one or both of the diols and dicarboxylic acids contain unsaturation; e.g., from...
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7858108 |
Elutable surface coating
Elutable coatings comprising protein resistant components and bioactive agent on medical devices are disclosed. The elutable coatings comprise labile linkers that can be cleaved under controlled...
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7838595 |
Water-soluble polymer alkanals
The present invention is directed to alkanal derivatives of water-soluble polymers such as poly(ethylene glycol), their corresponding hydrates and acetals, and to methods for preparing and using...
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7838592 |
Starch-based coating composition
There is provided a starch-based coating composition with excellent storage stability as a one-pack type paint, which can form coating films with excellent drying property, finished appearances,...
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7834088 |
Thioester-terminated water soluble polymers and method of modifying the N-terminus of a polypeptide therewith
The invention provides reagents and methods for conjugating a polymer specifically to the α-amine of a polypeptide. The invention provides monofunctional, bifunctional, and multifunctional PEGs ...
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7740883 |
Nanoparticles from chitosan
Methods are disclosed for preparing crosslinked core and core-shell nanoparticle polymers from chitosan. The final products of the present invention may be used as detergents and as additives for...
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7741311 |
Composition and method for treating occlusive vascular diseases, nerve regeneration, and wound healing
A composition and a method of treating a subject with respect to a pathological condition comprised by the subject. The composition comprises a sulfated saccharide conjugated to a polymer. The...
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7737240 |
Hydrogel functionalized with a polymerizable moiety and their uses as biosensors or bioreactors
The present invention relates to a new hydrogel functionalized with a polymerizable moiety, the polymerized hydrogels, films and gels comprising the same and their use for cells, proteins, DNA or...
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7723432 |
Method for the preparation of 1-benzotriazolyl carbonate esters of poly(ethylene glycol)
The invention provides a method for preparing a 1-benzotriazolylcarbonate ester of a water-soluble and non-peptidic polymer by reacting a terminal hydroxyl group of a water-soluble and non-peptidic...
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7713637 |
Coating containing PEGylated hyaluronic acid and a PEGylated non-hyaluronic acid polymer
Provided herein are a coating or a device (e.g., absorbable stent) that includes a PEGylated hyaluronic acid and a PEGylated non-hyaluronic acid biocompatible polymer and the methods of use thereof.
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7625961 |
Biopolymer and methods of making it
The present invention relates to a composition, which can be referred to as a biopolymer, including fermentation solid and thermoactive material. The present invention also includes methods of...
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7625552 |
Bioactive polymers for imparting bioactive character to hydrophobic medical article surfaces
According to an aspect of the present invention, bioactive polymers are provided which have (a) a hydrophilic bioactive portion and (b) at least one hydrophobic polymer group that is linked to the...
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7605232 |
Hydrogels for protein concentration
A method of concentrating proteins from whole blood comprising exposing whole blood to covalently crosslinked hydrogel to remove water from the blood into the hydrogel to thereby concentrate the...
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7517937 |
Biodegradable resin composition and biodegradable resin molded article
The present invention relates a biodegradable resin composition comprising an L-lactic acid unit-containing resin (1) and a D-lactic acid unit-containing resin (2). Also disclosed is a...
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7511095 |
Thioester-terminated water soluble polymers and method of modifying the N-terminus of a polypeptide therewith
The invention provides reagents and methods for conjugating a polymer specifically to the α-amine of a polypeptide. The invention provides monofunctional, bifunctional, and multifunctional PEGs ...
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7507474 |
Thermoplastic polymer composition comprising a hyperbranched polymer and articles made using said composition
The invention relates to thermoplastic compositions comprising a polymer matrix and an additive which modifies the rheological behavior of the matrix in the molten state. The purpose of the...
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7473733 |
Cationic graft-copolymer for non-viral gene delivery vector
A cationic graft-copolymer for a non-viral gene delivery vector comprising a unit derived from a cationic derivative of a water-soluble linear polymers having a hydroxyl groups, namely, a cationic...
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7416845 |
pH dependent ion exchange material, solid substrate having the material immobilized on its surface, and method of isolating a nucleic acid using the material or the solid substrate
Provided are a pH dependent ion exchange material having a carboxyl group, an amino group, and a polyethylene oxide moiety, which is used for isolating a nucleic acid, a solid substrate having the...
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7393503 |
Emissive polymers and devices incorporating these polymers
The present invention relates to a class of luminescent and conductive polymer compositions having chromophores, and particularly solid films of these compositions exhibiting increased luminescent...
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7390497 |
Poly(ester amide) filler blends for modulation of coating properties
Provided herein is a PEA polymer blend and coatings or implantable devices formed therefrom. The PEA polymer blend is formed of a PEA polymer and a material capable of hydrogen bonding with the...
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7385004 |
Enhanced lubrication in polyolefin closure with polyolefin grafted cyclodextrin
Thermoplastic polymer compositions in a closure can comprise a polymer, a modified vinyl polymer and a slip agent or polymer lubricant said modified polymer having a moiety comprising a...
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7368502 |
Hydroxyphenyl cross-linked macromolecular network and applications thereof
A dihydroxyphenyl cross-linked macromolecular network is provided that is useful in artificial tissue and tissue engineering applications, such as artificial or synthetic cartilage. The network is...
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7365123 |
Grafted cyclodextrin
Thermoplastic polymer compositions, films, continues, closures, laminates can comprise a modified vinyl polymer said modified polymer having a moiety comprising a cyclodextrin compound. The...
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7361726 |
Poly(hydroxyalkanoate-co-ester amides) and agents for use with medical articles
Polymers containing poly(hydroxyalkanoate-co-ester amides) and agents for use with medical articles are disclosed along with methods of fabricating medical articles comprising these polymers. The...
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7332566 |
Biocompatible crosslinked polymers with visualization agents
Biocompatible crosslinked polymers, and methods for their preparation and use, are disclosed in which the biocompatible crosslinked polymers are formed from water soluble precursors having...
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7270808 |
Cyclodextrin-based polymers for therapeutics delivery
The present invention relates to novel compositions of therapeutic cyclodextrin containing polymeric compounds designed as a carrier for small molecule therapeutics delivery and pharmaceutical...
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7238364 |
Compliant tissue sealants
An improved barrier or drug delivery system which is highly adherent to the surface to which it is applied is disclosed, along with methods for making the barrier. In the preferred embodiment, the...
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