Matches 351 - 400 out of 652 < 1 2 3 4 5 6 7 8 9 10 11 12 13 14 >
Match Document Document Title
3995041 Derivatives of 2-substituted-hydroxyanilino-hexahydro-2H-benzo[α]quinolizines  
2-Substituted-hydroxyanilino-hexahydro-2H-benzo[α]quinolizi nes of the structural formula, ##SPC1## In which R 1 is a hydrogen atom or an alkanoyl group of 2 to 4 carbon atoms and each of...
3994891 Tetrahydroisoquinoline compounds  
Tetrahydroisoquinoline compounds represented by the formula: ##SPC1## In which X is a hydroxy group, Y is a hydroxy group or Y taken with X is --O--CH 2 --O--, Z is hydrogen or a...
3991057 C-Piperazino-pyridine sulfonamides  
This invention relates to compounds of the formula: ##SPC1## Wherein R 1 in the 3- or 5-position is preferably a substituted sulfonamido or a carboxamido group whereas R 2 in the 2-, 4- or...
3989749 11,12-Secoprostaglandins  
This invention relates to 8,10-diaza-9-oxo(and thioxo)-11,12-secoprostaglandins and processes for their manufacture. These compounds have prostaglandin-like biological activity and are particularly...
3987176 Composition and use of 3,4-dihydropyridones as vasodilators and antihypertensive agents  
3,4-Dihydropyridones of the formula ##SPC1## Wherein R 1 is hydrogen, straight or branched chain alkyl, or --COOR' is a straight, branched or cyclic, saturated or unsaturated hydrocarbon or said...
3985896 Benzophenalenofurans  
The compounds are benzophenalenofurans having pharmacological activity, in particular, coronary vasodilator activity.
3985886 2-Amino-4,5-dihydropyridine derivatives and process for their preparation  
2-Amino-4,5-dihydropyridines-3,5-dicarboxylates substituted by lower alkoxy or lower alkylthio in the 6-position and optionally substituted in the 4-position by lower alkyl, phenyl, substituted...
3985758 1,4-Dihydropyridine derivatives  
There are provided novel 1,4-dihydropyridine derivatives, particularly 2,6-dimethyl-4-(3'-nitrophenyl)-1,4-dihydropyridine-3,5-dica rboxylic acid 3-β-(N-benzyl-N-methylamino)ethyl ester and...
3984558 1,3,5-Trisubstituted-1,2,4-triazole compounds used as bronchodilators  
Compounds useful in the treatment of asthma, the symptoms of allergy and in some instances in gout and hyperuricemia are described. The novel compounds are 1-substituted-1,2,4-triazoles being...
3984413 Phenoxyalkanecarboxylic acid esters of hydroxyalkyltheophyllines and method for their manufacture  
Phenoxyalkanecarboxylic acids are esterified with 7-(2-hydroxyethyl) theophylline or 7-(2,3-dihydroxypropyl) theophylline. The resulting esters have excellent antilipemic and anticholesterolemic...
3981882 Process for preparing 4-aryl of hetero-6-amino-3,4-dihydropyrid-2-one-3,5-dicarboxylic acid ester  
3,4-Dihydropyridones of the formula ##SPC1## Wherein R 1 is hydrogen, straight or branched chain alkyl, or --COOR' wherein R' is a straight, branched or cyclic, saturated or unsaturated...
3979456 Phenoxyalkylamines, process for their preparation and applications thereof  
This invention relates to phenoxyalkylamines having the formula: ##SPC1## In which n is zero or 1, R is hydrogen or a hydroxy group, R 2 is hydrogen, a hydroxy group or an alkyl group, R 2 being...
3978055 Arylamino pyrimidinic derivatives  
Compounds of the formula ##SPC1## Wherein Ar is phenyl or phenyl substituted by one or more halogens, by a trifluoromethyl or a methylenedioxy, by one or more methoxy, by an alkyl having one to 4...
3975391 5-[1-Hydroxy-2-(substituted-amino)]ethyl-8-hydroxy-3,4-dih ydrocarbostyril derivatives  
5-[1-HYDROXY-2-SUBSTITUTED-AMINO)]ETHYL-8-HYDROXY-3,4-DIHYDR OCARBOSTYRIL DERIVATIVES REPRESENTED BY THE FORMULA (I) ##SPC1## wherein R 1 and R 2 , which may be the same or different, each...
3974275 1,4-Dihydropyridine carboxylic acid esters useful as coronary vessel dilators and anti-hypertensives  
Certain 1,4-dihydropyridine carboxylic acid esters or their pharmaceutically acceptable non toxic salts are useful as coronary vessel dilators and antihypertensives.
3974213 13,14-Dihydro-15-substituted-ω-pentanorprostaglandins  
The 15 aryl substituted-ω-pentanorprostaglandins and various intermediates employed in their preparation. The novel prostaglandins of this invention have been found to have activity profiles...
3971826 15-Substituted-ω-pentanorprostaglandins  
The 15-substituted-ω-pentanorprostaglandins and various intermediates employed in their preparation. The novel prostaglandins of this invention have been found to have activity profiles comparable...
3971796 1,4-Dihydropyridine esters  
A new class of 1,4-dihydropyridines which are characterized by the presence of ester substitutes at positions 3 and 5 of the nucleus and by the presence of an alkoxyalkyl at position 2. The...
3971793 Certain 6-(dialkylamino, pyrrolidino and piperidino)ethoxy-4,7-dimethoxy-5-(3-phenyl-1-hydroxypropyl)2,3-dihydrob enzofurans  
A compound of the formula ##SPC1## In which R is hydrogen, hydroxy, halogen or alkoxy containing up to 3 carbon atoms, and ##EQU1## is dialkylamino in which the alkyls contain up to 3 carbon atoms,...
3968102 S-substituted-2-thioadenosines  
S-Substituted-2-thioadenosines represented by the formula (I): ##SPC1## wherein R is as defined hereinafter, useful as a platelet aggregation inhibitor and a coronary vasodilator.
3966948 Spasmolytic, vaso-dilating and anti-hypertensive compositions and methods  
1,4-Dihydropyridines of the formula: ##SPC1## Wherein R is hydrogen, straight, branched or cyclic lower alkyl, lower alkenyl, or lower alkinyl, unsubstituted or substituted by hydroxyl or alkoxy of...
3966814 1-Phenyl-2-(Naphthylalkyl-amino)-ethanols and salts thereof  
Compounds of the formula ##SPC1## Wherein A is alkylene of 2 to 6 carbon atoms, R 1 is hydrogen, lower alkyl, lower alkoxy, hydroxyl, or lower alkanoyloxy, R 2 is hydrogen, lower alkyl...
3966767 2-Amino-4 H-pyrane  
2-Amino-4 H-pyrane derivatives of the formula ##SPC1## Wherein R 1 and R 2 are the same or different and each is hydrogen or straight- or branched-chain alkyl; R 3 is straight- or...
3966764 Ligand determination of spin labeled compounds by receptor displacement-amphetamine analogs  
Compounds are provided for use in assays of organic compounds, where organic compounds of biological interest are determined at extremely low concentrations by combining in a medium, the...
3966724 1-(α-Aminomethylbenzyl)isoquinoline compounds  
Compounds having the structure: ##SPC1## In which R 1 and R 2 are alkoxy groups of one to four carbon atoms, R 3 and R 4 each is hydrogen or an alkoxy group of one to four carbon atoms, and R 5...
3962256 2-Aminomethyl benzimidazole derivatives  
Compounds having the formula ##EQU1## WHEREIN Ar is phenyl optionally substituted by one or more halogens, alkyl having 1 to 4 carbons or alkoxy containing up to 4 carbons, and R 1 and R 2 each...
3959474 2,6-Diamino-1,4-dihydropyridine-3,5-dicarboxylic acid esters used as coronary vessel dilators and anti-hypertensive agents  
2,6-Diamino-1,4-dihydropyridines bearing carbonyl functions in the 3- and 5-positions and being substituted in the 4-position by lower alkyl, phenyl, substituted phenyl or a heterocyclic group are...
3959369 Alkanolamine derivatives  
Novel 1-amidoaryloxy-3-amidoalkylamino-2-propanol derivatives, processes for their manufacture, pharmaceutical compositions containing them and methods of using them in the treatment of heart...
3959359 Phenoxyalkylamines, process for their preparation and therapeutical composition containing same  
This invention relates to phenoxyalkylamines having the formula: ##SPC1## Wherein R is a radical selected from the group consisting of hydrogen and hydroxy, R 2 is a radical selected from the...
3959296 1,4-Dihydropyridines  
Derivatives of 4-substituted phenyl 1,4-dihydropyridine 3,5-dicarboxylic acids substituted by lower alkyl groups in the 2- and 6-positions, are cardiovascular agents. The compounds, of which...
3959292 2-Amino-4,5-dihydropyridine derivatives  
4,5-Dihydropyridines bearing an N,N-disubstituted amino group in the 2-position, carbonyl functions in the 3- and 5-positions and being optionally substituted in the 6-position by lower alkyl or...
3959281 Piperazino substituted coumarin derivatives  
The present invention relates to new coumarin compounds useful as coronary dilators and having the formula ##SPC1## Or the hydrochloric acid addition salts thereof, and to methods of preparing same...
3957998 Use of 2,6-diamino-4-substituted-1,4-dihydropyridine-3,5-dicarboxylic acid esters for effecting coronary vessel dilation and treating hypertension  
2,6-Diamino-1,4-dihydropyridines bearing carbonyl functions in the 3- and 5-positions and being substituted in the 4-position by lower alkyl, phenyl, substituted phenyl or a heterocyclic group are...
3957995 Pharmaceutical composition comprising vincamine and theophylline  
The herein disclosed invention is directed to pharmaceutical compositions of vincamine and theophylline having cerebral vasodilator activity.
3957845 Trifluoromethyl-substituted phenyl acetonitriles  
Basically substituted phenylacetonitriles having also a trifluoromethyl substituent. The compounds are useful as coronary dilators.
3957809 Certain 2-alkyl-5-oxymethylthiazoles  
Novel thiazole derivatives of the formula ##EQU1## wherein R is alkyl of 2 to 12 carbon atoms and R 1 is selected from the group consisting of hydrogen, alkyl of 1 to 8 carbon atoms and acyl of an...
3954871 1-(4-Alkylthiopheny)-2-substituted amino-alcohols and their salts  
The new amino-alcohols according to the invention are represented by the formula ##SPC1## Wherein: R 1 represents a RS, RSO or RSO 2 group in which R is a linear or branched alkyl group (C 1 -C...
3954780 Propionic acid derivatives  
β-[Benzo(b)thienyl-3]propionic acid derivatives in the form of their amino esters (and salts thereof) are prepared. These compounds have spasmolytic, vasodilatatric, antiserotanic and local...
3953448 Piperazino-anilido compounds  
Novel 1,4-disubstituted piperazine compounds and pharmaceutical compositions incorporating such compounds in conjunction with orally, parenterally or rectally administrable pharmaceutically...
3952004 Stabilized E-series prostaglandins  
A lyophilized pharmaceutical composition comprising a prostaglandin of the E-series and an excipient selected from the group consisting of sodium chloride, cyclodextrin, succinic acid and...
3951994 Tetrahydroindolizine derivatives  
1,4-Dihydropyridines bearing carbonyl functions in the 3- and 5-positions, being optionally substituted by lower alkyl in the 6-position, being substituted in the 4-position by lower alkyl, phenyl,...
3951991 4-Aryl-6-amino-3,4-dihydropyrid-2-one-3,5-dicarboxylic acid ester  
3,4-Dihydropyridones of the formula ##SPC1## Wherein R 1 is hydrogen, straight or branched chain alkyl, or --COOR' wherein R' is a straight, branched or cyclic, saturated or unsaturated...
3951990 4-Aryl or hetero-6-amino-3,4-dihydropyrid-2-one-3,5-dicarboxylic acid ester  
3,4-Dihydropyridones of the formula ##SPC1## Wherein R 1 is hydrogen, straight or branched chain alkyl, or --COOR' wherein R' is a straight, branched or cyclic, saturated or unsaturated...
3951988 1,2-Pentamethylene-1,4-dihydropyridine derivatives  
1,4-Dihydropyridines bearing carbonyl functions in the 3- and 5-positions, being optionally substituted by lower alkyl in the 6-position, being substituted in the 4-position by lower alkyl, phenyl,...
3950336 2,6-Diamino-1,4-dihydropyridine derivatives  
2,6-Diamino-1,4-dihydropyridines bearing carbonyl functions in the 3- and 5-positions and being substituted in the 4-position by lower alkyl, phenyl, substituted phenyl or a heterocyclic group are...
3948923 Pentahydroqunolizine derivatives  
1,4-Dihydropyridines bearing carbonyl functions in the 3- and 5-positions, being optionally substituted by lower alkyl in the 6-position, being substituted in the 4-position by lower alkyl, phenyl,...
3947470 Substituted benzofurans and benzothiophenes  
The compounds of this invention are substituted benzofurans and benzothiophenes having pharmacological activity. In particular, these compounds have coronary vasodilator activity and are useful in...
3944551 N-Coumaranyl and chromanyl -methyl-or sulfur analogs thereof-N'- thiazolyl piperazines  
Disubstituted piperazines of the formula: ##SPC1## Wherein: n is 1 or 2; X is oxygen or sulfur; R is hydrogen or lower alkyl; Het is pyridyl, pyrimidinyl, pyridazinyl, pyrazinyl,...
3944549 Amino derivatives of 1,4-benzodioxan  
1-[2-(1,4-benzodioxanyl)methyl]-4-(2-hydroxyethyl)-piperazin e hemifumarate and the related compounds of formula: ##SPC1## In which R is hydrogen or alkyl; and A is --Z--OR 1 , --CH 2 CHOR" 1 CH...
3943140 2,3,5,6-Tetracarboxy-1,4-dihydropyridine derivatives  
1,4-Dihydropyridines bearing carboxy functions in the 3-, 5- and 6- or 2-, 3-, 5- and 6-positions and being substituted in the 4-position by phenyl, substituted phenyl, naphthyl, phenylalkyl or a...
Matches 351 - 400 out of 652 < 1 2 3 4 5 6 7 8 9 10 11 12 13 14 >