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9023898 Flushing solution  
A flushing solution is described which is suitable for use in surgical, in particular ophthalmological, operations and which contains a non-Newtonian fluid. The use of such a flushing solution is...
9018202 Methods for treating diseases of the retina  
Disclosed herein is a method of treating disorders of the retina comprising administering to a patient in need of such treatment a compound selected from the group consisting of olanzapine,...
9017725 Topical drug delivery systems for ophthalmic use  
Topical drug delivery systems for ophthalmic use including mixed nanomicellar formulations of water-insoluble drugs and methods of treating diseases affecting the posterior ocular segments are...
9006214 Composition for a topical ophthalmic clear colloidal liquid which undergoes a liquid-gel phase transition in the eye  
The present invention is directed to a topical ophthalmic composition for a liquid comprised of clear colloidal polar nanolipids delivered in submicron sized particles, aqueous colloidal...
8980957 Methods for the preparation of biocompatible polymers, the polymers and their uses  
The subject invention relates to a method of preparing a biocompatible polymer comprising epsilon-linked L-lysine having free alpha-amino and carboxy functions. The invention further encompasses...
8969385 Ocular formulations of norketotifen  
Ophthalmic compositions containing norketotifen and methods of making the same and the use thereof are disclosed. The methods also comprise administering to the eyes of a mammal in need thereof...
8962691 Retinoid replacements and opsin agonists and methods for the use thereof  
Compositions of and methods for using synthetic retinoids as retinoid replacements and opsin agonists are provided.
8961993 Method of treating retinitis pigmentosa  
Provided is a method for improving day photopic vision and/or cone-derived visual field and visual function in a subject suffering from a retinal disease or trauma including administering to the...
8946281 Ketorolac tromethamine compositions for treating or preventing ocular pain  
Compositions comprising ketorolac tromethamine at a therapeutically effective concentration of less than 0.5% are disclosed herein. Methods of treating or preventing ocular pain using said...
8940318 Hydrogel contact lens for sustained drug release and drug release method using hydrogel contact lens for sustained drug release  
Disclosed is a sustainedly drug-releasing hydrogel contact lens which can sustainedly release an anionic medicament such as an allergy-treating agent in a mildly irritating and effective manner...
8912236 Pharmaceutical composition for delivery of receptor tyrosine kinase inhibiting (RTKi) compounds to the eye  
The present invention relates to development of efficacious pharmaceutical implant compositions comprising an active agent in a therapeutically effective amount and a polyethylene glycol having a...
8906950 Ketorolac tromethamine compositions for treating or preventing ocular pain  
Compositions comprising ketorolac tromethamine at a therapeutically effective concentration of less than 0.5% are disclosed herein. Methods of treating or preventing ocular pain using said...
8889735 Method for treating asthenopia  
The present invention relates to a method for treating asthenopia, accommodative dysfunction or ocular pain comprising an administration of a specific prostaglandin compound to a mammalian...
8865776 Use of low molecular weight amino alcohols in ophthalmic compositions  
The use of low molecular weight amino alcohols in ophthalmic compositions is described. These compounds have been found to enhance the efficacy of anti-microbial preservatives.
8853251 Ester pro-drugs of [3-(1-(1H-imidazol-4-YL)ethyl)-2-methylphenyl] methanol for treating retinal diseases  
The present invention relates to method of treating retinal diseases in a subject in need of such treatment, which comprises administering a therapeutically effective amount of a composition...
8853268 Ophthalmic solution  
The present invention relates to an ophthalmic solution comprising a prostaglandin compound and viscosity-increasing compound. The ophthalmic solution of the invention is excellent in stability...
8829037 Optical correction  
The present disclosure describes compositions which improve visual acuity and to methods for their use.
8815946 Inhibition of proliferation and fibrotic response of activated corneal stromal cells  
Provided herein are methods of preventing a fibrotic response and/or scarring in a wound, comprising administering to a subject a composition comprising an amount of an amide or ester of an...
8791158 Methods of treating meibomian gland dysfunction  
The present invention includes methods for treating Meibomian gland dysfunctions. The invention also includes methods for improving tear lipid composition, for treating abnormal Meibomian gland...
8771715 Compositions and methods for treatment  
The present invention provides compounds and methods for the treatment of LFA-1 mediated diseases. In particular, LFA-1 antagonists are described herein and these antagonists are used in the...
8765758 Compositions and methods for eye whitening  
The invention provides compositions and methods for whitening of eyes. The provided compositions and methods utilize low concentrations of selective α-2 adrenergic receptor agonists. The...
8765787 Methods of treatment of xerophthalmia with self-preserving ocular formulations of norketotifen  
Self-preserving ophthalmic formulations containing norketotifen and methods of making the same and the use thereof in patients suffering from xerophthalmia are disclosed. The methods also comprise...
8758776 Compositions and methods for treatment  
The present invention provides compounds and methods for the treatment of LFA-1 mediated diseases. In particular, LFA-1 antagonists are described herein and these antagonists are used in the...
8754029 Ophthalmic composition  
The present invention provides an ophthalmic composition which stabilizes the tear film during wearing contact lens, prevents eye dryness, imparts a favorable sensation in using, is highly...
8741930 Treating xerophthalmia with norketotifen  
Methods of using a cycloheptathiophene compound for the treatment of xerophthalmia are described, as are formulations and compositions for such treatment.
8729128 Lipoxin A4 protection for cornea endothelial cells  
Lipoxin A4 and its analogs have been discovered to promote the cell proliferation of cornea endothelial cells, and thus promote the proper functioning of the labile tissue layer of cornea...
8722666 Sedative for use during eye surgery  
A drug for sedating a patient, and especially a smoker, during eye surgery. The drug includes a sedative such as midazolam in a mix with nicotine. The mixture is injected into the patient prior to...
8722728 Composition and method for treating dry eye syndrome  
The present invention provides for compositions, medicaments, and methods for treating or alleviating the symptoms of dry eye syndrome or chronic dry eye. More specifically, the present...
8709515 Nutritional supplement method  
The method comprises steps of: providing a nutraceutical including, in combination, 1.13 to 3 mg lutein and 18.8 to 51.2 mg omega fatty acids and 1.9 to 5.2 mg grape seed extract and 1.9 to 5.2 mg...
8710102 Use of beta-adrenoceptor antagonists for the manufacture of a medicament of the treatment of disorders of the outer retina  
Compositions and methods for treating disorders of the outer retina with β-adrenoceptor antagonists are disclosed.
8691874 Treatment of ophthalmic disorders using urea  
Methods for treating disorders of the eye and/or disorders of a nerve in a human or veterinary patient by delivering to the patient a therapeutically effective amount of a compound selected from...
8691289 Methods of treating outer eye disorders using high ORP acid water and compositions thereof  
The present invention relates to a method of treating an outer eye disorder selected from a cataract, neovascularization, keratitis, epithelium deficiency, or chronic opacity, by administering to...
8691876 Ophthalmic and contact lens solutions using choline  
The present invention relates to a lens care solution having 0.001 to about 5 weight percent of a low molecular weight amine of the general formula: where R1, R2, R3 and R4 are —H or low molecular...
8680078 Stable ophthalmic formulations  
Disclosed herein are stable formulations suitable for the treatment of glaucoma and ocular hypertension.
8679511 In-situ gel ophthalmic drug delivery system of estradiol or other estrogen for prevention of cataracts  
An in-situ gel ophthalmic drug delivery system for estrogen containing an estrogen, a solubilizing and complexing agent, a humectant, a sorbic acid or sorbic acid based stabilizer, an optional...
8673280 Pharmaceutical composition for intracellar acidification with cis-urocanic acid  
A pharmaceutically acceptable agent able to acidify the cell cytoplasm for the manufacture of a pharmaceutical composition useful for causing immunosuppression in a person or animal, where an...
8673937 Eye-drop preparation and use thereof  
Disclosed is a technique for preventing the decomposition of latanoprost (a thermally unstable substance) contained in an eye-drop solution to stabilize the eye-drop solution. Specifically...
8668920 Method, device, and system for delivery of therapeutic agents to the eye  
A method, device, and system for easier, consistent, and comfortable delivery of therapeutic agents to the front of the eye.
8669241 Ophthalmic composition  
The ophthalmic composition of the invention comprises (A) lecithin and (B) at least one refrigerant selected from the group consisting of camphor, borneol, eucalyptus oil, and bergamot oil. In the...
8664180 Ophthalmic compositions containing diglycine  
Ophthalmic composition that includes 0.05% w/v to 2% w/v diglycine or a salt thereof; 0.01 ppm to 3 ppm poly(hexamethylene biguanide); 1 ppm to 10 ppm α-[4-tris(2-hydroxyethyl)ammonium...
8658633 Methods and compositions for treating conditions of the eye  
Provided are methods and compositions for treating ocular conditions characterized by the presence of unwanted choroidal neovasculature, for example, neovascular age-related macular degeneration....
8658624 Pharmaceutical compositions for preventing and treating eye pathologies  
The present invention relates to pharmacology, medicine, opthalmology, and, in particular, concerns a class of chemical compounds of structure (I) and also their solvates, isomers or prodrugs...
8648107 Ketorolac tromethamine compositions for treating or preventing ocular pain  
Compositions comprising ketorolac tromethamine at a therapeutically effective concentration of less than 0.5% are disclosed herein. Methods of treating or preventing ocular pain using said...
8637070 Rapamycin formulations and methods of their use  
Described herein are liquid rapamycin formulations. Described herein are methods of treating or preventing diseases or conditions, such as choroidal neovascularization, wet AMD and dry AMD, and...
8637544 Neurite formation promoter  
The invention provides an agent for promoting ocular tissue neuritogenesis, containing N-(1-acetylpiperidin-4-yl)-4-fluorobenzamide or a pharmaceutically acceptable salt thereof, and an agent for...
8633181 Treatment of cutaneous hemangioma  
This invention concerns a method of treating hemangiomas with a beta blocker by applying the beta blocker onto the hemangiomas directly. The invention also concerns a combination therapy by using...
8618088 Methods of inhibiting choroidal neovascularization  
The present invention relates to compositions and methods for inhibiting unwanted angiogenesis, particularly those of ocular tissues. The treatment, inhibition, and/or prevention of choroidal...
8614235 CAI-based systems and methods for the localized treatment of ocular and other diseases  
The subject invention provides CAI compounds and formulations thereof, and methods for their use in the localized treatment of non-life threatening diseases. Formulations of CAI compounds of the...
8592450 Compositions and methods for treatment of eye disorders  
The present invention provides compounds and methods for the treatment of LFA-1 mediated diseases. In particular, LFA-1 antagonists are described herein and these antagonists are used in the...
8585938 UV-absorbers for ophthalmic lens materials  
UV absorbing compounds that are effective in blocking UV and short-wavelength blue light are disclosed. The UV absorbing compounds are particularly suitable for use in intraocular lens materials.