Patents in Class 514/9

Matches 51 - 100 out of 578

Match	Document	Document Title
51	7414023	Peptide ligands for prostate specific antigen The present invention relates to novel peptide ligands for prostate specific antigen (PSA) binding specifically with it and enhancing its enzyme activity, to a process for preparation of these...
52	7410945	Treatment of inflammatory bowel disease This invention relates to methods of treatment of inflammatory bowel disease, and especially to treatment of this condition with cyclic peptidic and peptidomimetic compounds which have the ability...
53	7405200	Use of oxytocin for the preparation of a pharmaceutical composition against cancer in situ and cervicitis A method of treating cancer in situ and cervicitis is disclosed. A pharmaceutical composition comprising at least one substance with oxytocin activity against cancer in situ and cervicitis and...
54	7390784	Administering bifunctional molecules containing a drug moiety and presenter protein ligand for therapy Bifunctional molecules and methods for their use in the production of binary complexes in a host are provided. The bifunctional molecule is a conjugate of a drug moiety and a presenter protein...
55	7378391	Cyclosporin alkyne analogues and their pharmaceutical uses The compounds of the present invention are represented by the chemical structure found in Formula I: or a pharmaceutically acceptable salt thereof, with X, R 0 , R 1 , and R 2 defined herein.
56	7375081	Therapeutic combination of a pneumocandin derivative and an antifungal agent There is described antifungal combination use of known antifungal agents such as the azoles or polyenes in combination with a lipopeptide compound antifungal agent. More particularly, the invention...
57	7371364	Cyclic peptide and imaging compound compositions and uses for targeted imaging and therapy The present invention relates to novel cyclic peptides that may be conjugated with imaging agents, including novel imaging agents. Specifically, it includes c(KRGDf; SEQ ID NO. 3) NIR imaging...
58	7371724	KAPREKY peptidomimetics and analogues thereof Analogues of the amino acid sequence KAPREKY and their use in screening for compounds which interacts with FcεRIα.
59	7368423	Composition and method for treating chronic allograft rejection The invention provides a composition and a method for preventing or ameliorating the causes of chronic allograft rejection of a donor organ by a transplant recipient. The method includes...
60	7368422	Semi-synthetic rearranged vancomycin/desmethyl-vancomycin-based glycopeptides with antibiotic activity Semi-synthetic glycopeptides that have antibacterial activity are based on modifications of a rearranged vancomycin or desmethyl-vancomycin scaffold, in particular, alkylation or acylation of the...
61	7368424	Acylated nonadepsipeptides The invention relates to nonadepsipeptides and process for their preparation, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular bacterial...
62	7365054	Methods for treatment of tumors and metastases using a combination of anti-angiogenic and immuno therapies The invention provides methods for treating tumors and tumor metastases in a mammal comprising administering, to a mammal in need of treatment, a therapeutic amount of an antagonist sufficient to...
63	7364754	Ceramic based nanoparticles for entrapping therapeutic agents for photodynamic therapy and method of using same The present invention provides methods and compositions for photodynamic therapy. The composition comprises ceramic nanoparticles in which a photosensitive drug/dye is entrapped. The ceramic...
64	7364747	Process and product for inhibiting or preventing bacterial infections The combination of a polymyxin composition and a hop composition produces unexpected and synergistic activity against gram positive bacteria.
65	7348311	Derivatives of dehydrodidemnin B Dehydrodidemnin B with useful biological activity has formula (1). It can be isolated from natural sources or synthesized, and it forms active derivatives
66	7329644	Preparation and use of cyclic and branched peptides and their labelled derivatives as therapeutic agents, cholecystokinin agonists or antagonists, and diagnostic agents to identify and locate tumours This patent application describes the preparation of cyclic and branched peptides of general formula (I) and their conjugated derivatives labelled with a paramagnetic or radioactive metal. The...
67	7326682	Conotoxin peptides The invention relates to an isolated, synthetic or recombinant χ-conotoxin peptide having the ability to inhibit a neuronal amine transporter, nucleic acid molecules encoding all or part of such...
68	7326683	Treatment of membrane-associated diseases and disorders using lantibiotic containing compositions Compositions useful for treating membrane-associated diseases, conditions, and disorders, including inflammatory diseases, dry mouth, primary ciliary dyskinesia and platelet aggregating disorders,...
69	7323444	Use of kahalalide compounds for the manufacture of a medicament for the treatment of psoriasis Kahalalide compounds, in particular kahalalide F, are of use in a method to treat a mammal suffering from skin disease with avoiding toxicity and leading to clinical improvement.
70	7314858	Retrocyclins: antiviral and antimicrobial peptides Retrocyclin peptides are small antimicrobial agents with potent activity against bacteria and viruses. The peptides are nonhemolytic, and exhibit minimal in vitro cytotoxicity. A pharmaceutical...
71	7314861	Melanin-concentrating hormone analogs The present invention features truncated MCH analogs active at the melanin concentrating hormone type 2 receptor (MCH-2R) and uses of such analogs. Truncated MCH analogs described herein include...
72	7314863	Cyclic peptidomimetic urokinase receptor antagonists The present invention relates to cyclic peptides as inhibitors of urokinase binding to the urokinase receptor. Said cyclic peptides are suitable as pharmaceutical active substances for disorders...
73	7314862	Antitumor agent The present invention relates to an antitumor agent containing a histone deacetylase inhibitor and a topoisomerase II inhibitor in combination. This combination has been found to exhibit a...
74	7312195	Cyclised conotoxin peptides This invention relates to cyclised conotoxin peptides, processes for their preparation and their pharmaceutical use.
75	7288520	Cyclosporin compositions A composition is disclosed herein comprising from about 0.001% to about 0.4% cyclosporin A, castor oil, and a surfactant selected from the group consisting of alcohol ethoxylates, alcohols, alkyl...
76	7288519	Fas peptide mimetics and uses thereof Exocyclic peptide mimetics that disable Fas were developed. A three dimensional model of the Fas receptor-ligand complex was constructed and structurally predicted regions of the receptor that were...
77	7285534	Corticotropin-releasing hormone analogs and their uses This invention provides members of the corticiotropin-releasing hormone superfamily and peptide analogs thereof wherein the 38 th amino acid from the N-terminus is D-Nle, i.e. [D-Nle 38 ]-CRH...
78	7276228	Methods for treating hematological disorders through inhibition of DNA methylation and histone deacetylase Methods are provided for treating hematological disorders by inhibition of DNA hypomethylation and histone deacetylase. Such disorders include, for example, acute promyelocytic leukemia, acute...
79	7273846	Selective melanin-concentrating hormone type-1 receptor agonists The present invention features truncated hMCH analogs selectively active at MCH-1R over MCH-2R. Using amino acid numbering provided in hMCH, the featured analogs contain an X 6 which is either a...
80	7271147	Antibiotics, tripropeptins and process for producing the same By culturing Lysobacter sp. BMK333-48F3 (deposit number of FERM BP-7477), an antibiotic, tripropeptin Z, tripropeptin A, tripropeptin B, tripropeptin C or tripropeptin D represented by the...
81	7256174	Somatostatin and somatostatin agonists for treating insulin insensitivity and Syndrome X The present invention relates to a method of treating insulin resistance or Syndrome X by administering a therapeutically effective amount of a somatostatin agonist or a pharmaceutical composition...
82	7253146	Template-fixed peptidomimetics with antimicrobial activity Template-fixed β-hairpin peptidomimetics of the general formulae (I) and (II) wherein Z, Z1 and Z2 are template-fixed chains of 8 to 16 α-amino acid residues which, depending on their positions...
83	7250397	Antiarrhythmic peptides Disclosed are novel peptides including antiarrhythmic peptides that have improved stability. Further disclosed are compositions that include such peptides and methods of using the compositions...
84	7232798	Neuroprotection and neuroegenisis by administering cyclic prolyl glycine The invention relates to the use of cyclic Prolyl Glycine (“cyclic PG” or “cPG”) and analogs and mimetics thereof, as neuroprotective agents for the treatment and or prevention of...
85	7232802	Compositions and methods for promoting myocardial and peripheral angiogenesis Methods, compositions and devices are disclosed for use in growing new blood vessels to restore or improve blood flow to ischemic tissues and organs of the body. Compositions comprising IGD...
86	7232799	Streptogramin derivatives and compositions thereof The present invention discloses and claims pharmaceutical compositions comprising Group A streptogramin derivatives of formula (I) and salts thereof in combination with at least one natural group B...
87	7226905	Process for the preparation of cyclosporin derivatives The invention concerns a novel method for preparing an intermediate polyanion for preparing cyclosporin derivatives by treating a cyclosporin with a hexamethyldisilazane metal salt, optionally in...
88	7217690	Compositions of sunflower trypsin inhibitors The present invention provides methods of using small cyclic peptides that can inhibit or prevent skin irritation caused by proteolytic activity.
89	7205278	Stabilized proteins with engineered disulfide bonds The present invention relates to methods of introducing one or more cysteine residues into a polypeptide which permit the stabilization of the polypeptide by formation of at least one bond,...
90	7205279	Pharmaceutical compositions This invention provides a microemulsion pre-concentrate comprising a difficultly soluble active agent and a carrier medium comprising 1) a hydrophilic phase which comprises dimethylisosorbide...
91	7199100	Cyclic peptides, method for preparing and use as angiogenesis inhibitors or activator The invention relates to cyclopeptides, the method of their preparation and their utilization as inhibitors or activators of angiogenesis. These cyclopeptides comprise the following peptide...
92	7199101	Gelling agent for oil A gelling agent for an oil, which contains at least one compound (A) and at least one compound (B), and a gel composition containing the gelling agent and an oil: wherein R 1 is a straight...
93	7192920	Derivatives of echinocandine, their preparation process and their use as antifungals A subject of the invention, in all possible isomer forms as well as their mixtures, is the compounds of formula (I): in which either R 1 : H or CH 3 and R 2 : cyclohexyl substituted by...
94	RE39496	Kahalalide F and compositions and uses thereof Kalahide Kahalalide F, of formula I below, may be isolated from a sacoglossan. The compound may be used in the manufacture of pharmaceutical compositions or in the treatment of tumors or viral...
95	7169756	Streptogramin antibiotics Disclosed is a cyclic peptide antibiotic in which an enzyme-sensitive bond is replaced by an enzyme-resistant bond.
96	7166594	Streptogramin derivatives, their preparation and compositions containing them Group A streptogramin derivatives of general formula (I) in which: R 1 represents a halogen atom or an azido or thiocyanato radical, R 2 represents a hydrogen atom or a methyl or ethyl...
97	7166572	Cyclohexapeptide compounds, processes for their production and their use as a pharmaceutical A cyclohexapeptide compound of general formula (I), wherein R 1 is C 1 –C 20 alkyl; C 9 –C 20 alkenyl; C 9 –C 20 alkoxyphenyl; an aryl group selected from: phenyl, biphenyl, terphenyl and...
98	7157423	Fumaric acid amides Fumaric acid amides of the general formula (I) wherein R 1 represents OR 3 or a D- or L-amino acid radical —NH—CHR 4 —COOH bonded via an amide bond, wherein R 3 is hydrogen, a...
99	7157424	Pharmaceutical compositions for hepatitis C viral protease inhibitors Disclosed are pharmaceutical compositions of hepatitis C viral protease inhibitors, and methods of using these compositions for inhibiting the replication of the hepatitis C virus (HCV) and for the...
100	7157419	Growth factor binding molecules Growth factor binding molecules having a plurality of peptide loops attached to a non-peptide organic scaffold, preferably having pseudo-six amino acid peptide loops with four amino acid...

Matches 51 - 100 out of 578

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