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7153526 |
Treatment of gastrointestinal infections
A method for combating bacterial infections affecting the gastrointestinal system of humans and animals is provided. The method is achieved by diagnosing a bacterial infection affecting the...
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7135197 |
Stable pharmaceutical composition useful for treating gastrointestinal disorders
The present invention provides a pharmaceutical composition comprising at least one pharmaceutically acceptable bismuth-containing compound, at least one pharmaceutically acceptable...
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7118761 |
Method for producing a silver-containing wound care device
Wound care devices having a topically applied silver-based antimicrobial finish are provided. The finish comprises at least one silver ion-containing compound and at least one binder compound. The...
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7115586 |
Non-inclusion cyclodextrin complexes
The invention provides a number of methods for enhancing the aqueous solubility of an active ingredient which is insoluble or sparingly soluble in water. In one preferred embodiment, solubilization...
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7084132 |
Artemisinins with improved stability and bioavailability for therapeutic drug development and application
A stable form of artemisinin wherein an artelinic acid or artesunic acid is complexed with cyclodextrin analogs, preferably, β-cyclodextrin. The complexed cyclodextrin artemisinin formulation...
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6974594 |
Method of preparing biological materials and preparations produced using same
Methods for preparing products containing moisture-sensitive materials, including biological materials such as proteins, peptides or live cells, comprising at least the steps: (i) providing a...
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6930119 |
Liquid pharmaceutical composition
This invention relates to new pharmaceutical compositions and methods for their preparation, and in particular it relates to taste-masked liquid compositions comprising a solution of a histamine H...
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6828334 |
Fenofibrate-cyclodextrin inclusion complexes and their pharmaceutical composition
The present invention relates to pharmaceutical compositions containing fenofibrate in the form of an inclusion complex with cyclodextrin, having high dissolution profile and in vivo enhanced...
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6824792 |
Bioadhesive composition
This invention relates to a method of producing a bioadhesive composition comprising the steps of preparing a solution of a solvent and a polymer mixture wherein the polymer mixture comprises at...
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6814978 |
Process for preparing a soft tablet
The invention relates to a process for preparing a soft tablet capable of being chewed or disintegrated in the oral cavity. The tablet is prepared by forming a tablet having a friability of less...
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6790453 |
Encapsulation compositions and process for preparing the same
Encapsulation compositions in which an encapsulate (A) is encapsulated in a matrix (B) may be prepared by: (i) mixing matrix (B) with a liquid plasticizer and encapsulate (A) in an extruder, to...
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6761903 |
Clear oil-containing pharmaceutical compositions containing a therapeutic agent
The present invention relates to pharmaceutical compositions and methods for improved solubilization of triglycerides and improved delivery of therapeutic agents. Compositions of the present...
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6747015 |
Low molecular weight polymannuronate
Disclosed is a polymannuronate composition including polymannuronate having molecular weight from about 4,000 to about 500,000 in a high purity. The composition can be used in producing nutritional...
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6660300 |
Method of use of a biphasic controlled release delivery system for high solubility pharmaceuticals and method
A biphasic controlled release delivery system for pharmaceuticals which have high water solubility, such as the antidiabetic metformin HCl salt, is provided which provides a dosage form that has...
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6656974 |
Foam materials
An absorbent foam material which comprises a solid, cross-linked form of an anionic polymer (e.g. an alginate) and fibers or other cation contributing polymeric particulates which have donated...
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6656508 |
Sustained-release alginate gels
The present invention relates to sustained-release formulations using alginate gel beads and methods thereof.
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6649191 |
Orally administrable compositions comprising cation cross-linked polysaccharide and a polymer digestible in the lower gastrointestinal tract
Orally administrable compositions comprising cation cross-linked polysaccharides are provided. The compositions have the ability to mask the taste and delay the release of an active material...
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6620432 |
Phenytoin sodium pharmaceutical compositions
A pharmaceutical composition is provided containing an admixture of phenytoin sodium and an erodible matrix which extends the release of the phenytoin sodium over about a two hour period. The...
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6610673 |
Solid dose forms containing bismuth
A swallowable, solid dose form composition for treating upper gastrointestinal tract distress containing bismuth subsalicylate, carbonate or bicarbonate salt, disintegrating agent, anionic or...
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6610667 |
Compositions for treatment of disorders of the oesophagus
Pharmaceutical compositions having improved bioadhesive properties are produced by combining an alginate, xanthan gum and/or a carageenan gum and a glucomannan and/or a galactomannan. The...
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6602592 |
Moisture-retentive cooling gel, moisture-retentive cooling gel laminate, and moisture-retentive cooling plaster
The present invention provides a moisture-retentive cooling gel, a laminate thereof, and a moisture-retentive cooling plaster, which offer moisture-retaining and cooling effects for a controlled...
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6569463 |
Solid carriers for improved delivery of hydrophobic active ingredients in pharmaceutical compositions
The present invention provides solid pharmaceutical compositions for improved delivery of a wide variety of pharmaceutical active ingredients contained therein or separately administered. In one...
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RE38112 |
Process for improving glucose metabolism, satiety, and nutrient absorption in companion animals
A process for feeding an animal a diet which alters the function and morphology of the gastrointestinal tract (GIT), a large lymphoid organ in the animal and which improves glucose metabolism,...
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6500459 |
Controlled onset and sustained release dosage forms and the preparation thereof
A pharmaceutical composition for controlled onset and sustained release of an active ingredient, said composition comprising: (i) a core comprising: (a) an active ingredient; (b) a hydrophilic...
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6495163 |
Moisture barrier film coating composition, method and coated form
A dry moisture barrier film coating composition for forming a moisture barrier film coating for pharmaceutical tablets and the like comprises polyvinyl alcohol, soya lecithin, and optionally a flow...
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6475521 |
Biphasic controlled release delivery system for high solubility pharmaceuticals and method
A biphasic controlled release delivery system for pharmaceuticals which have high water solubility, such as the antidiabetic metformin HCl salt, is provided which provides a dosage form that has...
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6475510 |
Process for manufacturing bite-dispersion tablets
This invention relates to a method for the manufacture of Bite-dispersion tablets which disperse easily and quickly in the oral cavity, after a gentle bite, without the aid of water, and if...
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6458763 |
Bone sialoprotein-based compositions for enhancing connective tissue repair
The present invention is directed to bioactive compositions that induce the repair of damaged or diseased connective tissues upon contact of the damaged or diseased tissues with the composition in...
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6447811 |
Pesticide against plant-pathogenic microorganisms
A formulation comprising lactoperoxidase, thiocyanate and/or iodide and a hydrogen peroxide donor system, in particular glucose oxidase and glucose, is useful for controlling plant-pathogenic...
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6432449 |
Biodegradable sustained-release alginate gels
The present invention relates to sustained-release formulations using biodegradable alginate delayed gels or particles and methods thereof.
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6419956 |
Odor-masking coating for a pharmaceutical preparation
A coating for masking or reducing the detectable presence of certain characteristic odor or odors, taste or tastes of pharmaceutical preparations, particularly Valerian extracts, is described. The...
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6395307 |
Pourable alginate compositions
An aqueous pourable liquid composition comprising a high concentration of sodium alginate and an alkali metal bicarbonate, wherein the sodium alginate has an average mannuronic acid residue to...
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6375985 |
System and method for producing drug-loaded microparticles
Method and system of producing microparticles loaded with biologically active drugs, including proteins such as ICAM-1, for controlled release of the drugs in a nasal passageway. The method...
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6375981 |
Modified starch as a replacement for gelatin in soft gel films and capsules
Film-forming compositions are disclosed that can comprise, on a dry solids basis, 25 to 75 percent by weight of certain starch derivatives having a DE less than about 1, 25 to 75% plasticizer, and...
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6372255 |
Tablet for instant and prolonged release of one or more active substances
A multi-layer tablet for the instant and prolonged release of active substances comprises at least two layers where the first outer layer comprises a mixture of excipients and an active substance,...
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6358525 |
Sustained release polymer blend for pharmaceutical applications
A pharmaceutical composition has a blend of at least first and second components and a medicament in a sufficient amount to be therapeutic where the first component is hydroxypropylcellulose (HPC)...
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6352720 |
Pharmaceutical formulations comprised of compacted amoxicillin granulates
The present invention discloses tablet formulations, produced by dry roller compaction comprising compacted granulates of a mixture of a medicament and an intra-granular disintegrant. The...
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6346268 |
Sustained release formulation containing three different types of polymers and tablet formed therefrom
Depot drug formulations include the pharmaceutical itself and a three component release rate controlling matrix composition. The three components of the matrix composition are (1) a pH dependent...
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6326028 |
Alginate and gellan gum as tablet coating
This invention relates to coatings employed to coat medicinal tablets. Such tablets include but are not limited to small pellet(s) of medication to be taken orally. In particular this invention...
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6267986 |
Process for the preparation of a controlled drug delivery system containing pseudoephedrine and a long acting antihistamine
This invention relates to a process for the preparation of a controlled release pharmaceutical composition comprising two discrete zones wherein the first discrete zone comprises therapeutically...
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6267985 |
Clear oil-containing pharmaceutical compositions
The present invention relates to pharmaceutical compositions and methods for improved solubilization of triglycerides and improved delivery of therapeutic agents. Compositions of the present...
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6261598 |
Carotenoid formulations, comprising a mixture of B-carotens, lycopene and lutein
Carotenoid formulations comprising a mixture of β-carotene, lycopene and lutein, and the use thereof in human and animal foods, cosmetics and pharmaceuticals.
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6224905 |
Biconvex rapidly disintegrating dosage forms
A method for preparing solid rapidly disintegrating dosage forms shaped as biconvex tablets having symmetrical top and bottom surfaces and dosage forms obtainable thereby.
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6217903 |
Sustained release polymer blend for pharmaceutical applications
A pharmaceutical composition has a blend of at least first and second components and a medicament in a sufficient amount to be therapeutic where the first component is ethylcellulose (EC) and the...
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6194001 |
Tablet dosage form of clavulanic acid and amoxycillin comprising a trehalose excipient
Provided are tablet formulations in one embodiment comprising clavulanic acid or salt thereof, amoxycillin, and trehalose. The trehalose is, for example, amorphous anhydrous trehalose. The...
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6149940 |
Tablet with controlled release of alfuzosine chlorhydrate
Pharmaceutical tablet which consists of: a) a first layer having the property of swelling considerably and quickly on contact with aqueous biological fluids, the first layer being produced by...
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6136334 |
Medical uses of in situ formed gels
Balanced pH, hyperosmotic, hypoosmotic, or isoosmotic gels are ideal vehicles for drug delivery. They are especially suited for topical body cavity or injection application of drugs or diagnostic...
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6110497 |
Pharmaceutical formulations
Tablet formulations having a structure comprising compacted granulates of a mixture of a medicament and an intra-granular disintegrant, the granulates being compacted together into a tablet with an...
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6103269 |
Solid bodies containing active substances and a structure consisting of hydrophilic macromolecules, plus a method of producing such bodies
The invention relates to accurately meterable shaped articles, for example granules or pellets, containing hydrophilic macromolecules, active compounds and optionally further pharmaceutically...
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6083531 |
Fast disintegrating oral dosage form
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