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7615593 |
Bifunctional-modified hydrogels
Disclosed are hydrogels wherein a polymer matrix is modified to contain a bifunctional poly(alkylene glycol) molecule covalently bonded to the polymer matrix. The hydrogels can be cross-linked...
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7612115 |
Aqueous pharmaceutical compositions
The present invention has an object to provide an antibacterial aqueous pharmaceutical composition and an aqueous pharmaceutical composition which have a sufficiently low gelation temperature even...
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7597897 |
Medicinal compositions and method for the preparation thereof
Methods for the manufacture of medicinal compositions are described. A method for the manufacture of a medicinal composition according to the invention comprises: (a) Providing a biocompatible...
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7592341 |
Peptide-enhanced corneal drug delivery
Improved methods and preparations are provided for ocular administration of therapeutic drugs. The preparations include respective quantities of a drug and a peptide which enhances transport of the...
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7589238 |
Treatment of hyperphosphatemia using crosslinked small molecule amine polymers
Anion-binding polymers are described. The anion-binding polymers in some cases are low swelling anion-binding polymers. In some cases, the anion-binding polymers have a pore volume distribution...
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7569643 |
Reverse thermal gellation polymer of chain-extended optional polyester-terminated PEO-PPO-PEO
The present invention relates to novel polymeric compositions based upon A n (BCB)A n polyester/polyether multi-blocks. Compositions according to the present invention exhibit unexpectedly...
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7566763 |
Stable dispersion concentrates
The invention provides dispersion concentrates comprising at least one polymer obtainable by free-radical copolymerization of
A) acryloyldimethyltauric acid and/or acryloyldimethyltaurates, B)...
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7563824 |
Clathrate complexes formed by hyaluronic acid derivatives and use thereof as pharmaceuticals
A clathrate formed by: a hyaluronic acid derivative (a), a hyaluronic acid derivative (b 1 ) different from (a), and being able to form a clathrate with (a) and/or a component (b 2 ) not containing...
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7560493 |
Cosmetic and/or dermatological composition containing at least one oxidation-sensitive hydrophilic active principle and at least one N-vinylimidazole polymer or copolymer
The invention relates to a composition for topical use containing, in a physiologically acceptable medium having an aqueous phase, at least one oxidation-sensitive hydrophilic active principle and...
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7560492 |
Polysulfone block copolymers as drug-eluting coating material
A polymeric composition comprising a polysulfone polymer and an elastomeric polymer for use as a coating composition for coating an implantable device, such as a DES, and methods of making and...
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7550512 |
Medical polymers and uses thereof
The present invention provides a polyethylene glycol derivative having sugar residue-containing side chains and carboxyl group-containing side chains, and a method of preparing the same. The...
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7550444 |
Composition and method for preparing biocompatible surfaces
The invention provides methods and compositions for providing biocompatible surfaces to medical articles. In particular the invention provides biocompatible coatings with heparin activity. In some...
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7547752 |
Scalp treatment
A composition for topical application to the scalp comprises (i) an anti-dandruff agent; (ii) conjugated linoleic acid; and (iii) a cosmetically acceptable diluent or carrier.
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7544348 |
Liquid formulations for the prevention and treatment of mucosal diseases and disorders
Stable, viscous, mucoadhesive aqueous compositions which are useful for the prevention and treatment of ulcerative, inflammatory, and/or erosive disorders of mucous membranes, especially mucositis.
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7540906 |
Metal salts of hydrolyzed olefin/maleic anhydride copolymers and their use as wood preservatives
Complexes of copper and/or zinc with hydrolyzed olefin/maleic anhydride copolymers were solubilized in ammoniacal solution providing preservative solutions that fully penetrate wood. With loss of...
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7534819 |
Compositions and methods for intracellular delivery of biotinylated cargo
The invention provides compositions for intracellular delivery of biotinylated cargo. The compositions comprise a complex formed between (a) a fusion protein comprising a protein transduction...
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7528176 |
Carbonyl-functionalized thiophene compounds and related device structures
Carbonyl-functionalized oligo/polythiophene compounds, and related semiconductor components and related device structures.
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7517914 |
Controlled degradation materials for therapeutic agent delivery
According to an aspect of the present invention, polymeric release regions are provided, which contain one or more partially biodegradable progenitor polymers and which control the release of one...
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7514095 |
Fabrication of drug loaded biodegradable polymer fibers
The invention provides tissue engineering compositions and methods wherein three-dimensional matrices for growing cells are prepared for in vitro and in vivo use. The matrices comprise...
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7507421 |
Hydroxycitric acid salt composition and method of making
Disclosed is a hydroxycitric acid salt composition comprising calcium and potassium salts of hydroxycitric acid, preferably in a defined proportion which yields a very pure, stabilized preparation...
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7501455 |
Pharmaceutical compositions containing plasma protein
The invention is related to water-soluble products and pharmaceutical formulations in solid or liquid form mainly for parenteral use. They consist of or comprise a therapeutically active substance...
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7491749 |
At least one polyamide polymer in a cosmetic composition comprising at least one solid substance having a melting point of 45 degrees C. or greater
Cosmetic compositions comprising at least one structuring polymer chosen from polymers of following formula (I):
in which n denotes a number of amide units, such that the number of ester groups...
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7485670 |
Systems and methods for controlling and forming polymer gels
In preferred embodiments, the present invention provides methods of controllably making a vinyl polymer hydrogel having desired physical properties without chemical cross links or radiation. The...
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7485617 |
Osteoinductive materials
The present invention concerns improved osteoinductive materials comprising matrix materials and morphogenetic roteins, wherein depending on the subject matter the proteins may be dimeric or...
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7482381 |
Artificial muscle hydrogel blends reversibly electroactuated near neutral pH, implantable actuating devices, and methods using the same
A novel artificial muscle material and miniature valves and micropumps made therefrom are provided. The artificial muscle material bends reversibly when electroactuated by applying low voltage, in...
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7479490 |
Pellet for a presurrized pipeline
A system of equipment allowing addition of solid materials to a pressurized pipeline wherein said solid material is conveyed in such a way as to be readily dissolved by the liquid in said pipeline....
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7470657 |
Cleansing composition containing an amphiphilic polymer
The present patent application relates to a cleansing composition comprising in an aqueous medium at least one surfactant selected from alkylpolyglycosides, maltose esters, glycerolated fatty...
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7465440 |
Process for preparing water-soluble or water-dispersible polyether-containing polymers and the use thereof as coating agents, binders and/or film-forming excipients in pharmaceutical dosage forms or packaging materials or as additives in cosmetic, dermatological or hygienic preparations
A process for preparing graft copolymers of polyvinyl esters by polymerization of
a) at least one vinyl ester of aliphatic C 1 -C 24 -carboxylic acids in the presence of b) polyethers which are...
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7449605 |
Crosslinked amine polymers
The present invention provides methods and compositions for the treatment of ion imbalances. In particular, the invention provides polymeric and pharmaceutical compositions comprising crosslinked...
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7442721 |
Durable biocompatible controlled drug release polymeric coatings for medical devices
Disclosed herein are biocompatible durable controlled drug releasing polymeric coatings for medical devices. The drug release rates of the polymers are controlled by adjusting monomer ratios and...
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7435790 |
Dihydroxypropyl cysteine peptide and agent containing this peptide
The invention relates to a S-(2,3-dihydroxypropyl)-cysteine peptide which has two long-chain fatty acids bonded in the form of esters at the dihydroxypropyl group, and which has the following...
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7429619 |
Polyacrylic film forming compositions
Water soluble, gelatin-free dip coatings for substrates comprising an acrylic film former; a paraben plasticizer; and a secondary plasticizer such as polyvinylpyrrolidone, polyethylene glycol 300,...
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7425581 |
Temperature sensitive polymers
The present invention relates to compositions comprising polymers whose solubility characteristics can be changed by incubation and particularly poly (N-(2-hydroxypropyl)methacrylamide...
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7423028 |
Injectable pharmaceutical compositions comprising sodium diclofenac and β-cyclodextrin
Injectable pharmaceutical compositions are described comprising sodium diclofenac, a β-cyclodextrin and a polysorbate, suitable for subcutaneous and intramuscular administration.
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7419687 |
Delivery vehicle for silver ions
A delivery vehicle for a silver ion source such as silver nitrate and the like, suitable for use in the treatment of menorrhagia, comprises a plurality of physiologically inert beads bearing a...
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7419685 |
Process for producing solid dosage forms
Solid dosage forms containing at least one polymer binder, at least one active ingredient and, where appropriate, conventional additives, wherein a physiologically tolerated, water-swellable graft...
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7407671 |
Temperature controlled solute delivery system
A system for delivering solute to a target location within a mammalian body, the system including a medical device, a thermosensitive cellulose gel structure over the medical device, and a...
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7405042 |
Method of extracting nucleic acid or protein using dendrimers and dendrimer-compositional substances
The present invention relates to a method of extracting nucleic acid or protein, in which multi-layer dendrimers are formed on the surface of fine particles, amino radicals for capturing nucleic...
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7402318 |
Medical devices having antimicrobial coatings thereon
The present invention provides a medical device, preferably a contact lens, which comprises an antimicrobial coating including at least one layer of polyquat of formula (I) or (II). The...
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7393840 |
Formulation based on heparin, glycosaminoglycan or heparinoid, use of the formulation and the formulation base
The present invention relates to formulations based on at least one heparin, glycosaminoglycan or heparinoid and on a formulation base with a lipid component and a polymer component. The use of...
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7388032 |
Sustained release compositions, process for producing the same and utilization thereof
A sustained-release composition containing a hydroxynaphthoic acid salt of a biologically active substance and a biodegradable polymer, a method of its production, and a pharmaceutical composition...
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7384984 |
Reactive hydrophilic oligomers
Hydrophilic compositions are described, which are prepared from a first component oligomer containing pendent hydrophilic groups and pendent reactive functional groups capable of reaction at...
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7381751 |
Antimicrobial composition for medical articles
An antimicrobial composition is formed from about 5 to about 25 wt % of an antimicrobial formulation and about 75 to about 95 wt % of a silicone resin. The antimicrobial formulation is formed from...
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7381426 |
Targeted delivery of bioactive factors to the systemic skeleton
The invention provides methods and compositions for the delivery of bioactive factors to the systemic skeleton. The methods of the invention allow targeted delivery of bioactive factors to bone...
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7381424 |
Hydrostatic delivery system for controlled delivery of agent
The present invention provides a hydrostatic delivery system comprising a hydrostatic couple and an agent of interest. The hydrostatic couple comprises, at least one hydrodynamic fluid-imbibing...
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7381422 |
Method for producing sterile polynucleotide based medicaments
The present invention relates to a novel method for producing formulations comprising a polynucleotide, block copolymer and cationic surfactant. The formulations produced by the current method are...
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7374778 |
Enhanced transport using membrane disruptive agents
Compositions and methods for transport or release of therapeutic and diagnostic agents or metabolites or other analytes from cells, compartments within cells, or through cell layers or barriers are...
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7371781 |
Tumor environment-induced ligand-expressing nanocarrier system
Drug delivery compositions for specific delivery of a drug to a tumor are described. These compositions include a core for sequestering the drug and a shell to which a ligand is attached for...
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7364752 |
Solid dispersion pharamaceutical formulations
A pharmaceutical composition is disclosed which comprises a solid dispersion of an HIV protease inhibitor in a water soluble carrier, such as PEG, having enhanced bioavailability and improved...
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7357949 |
Encapsulated inorganic antimicrobial additive for controlled release
The invention relates to a microcapsule comprising an inorganic antimicrobial agent coated with a hydrophilic polymer. The hydrophilic polymer is able to absorb sufficient water as to enable the...
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