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7189413 |
Drug delivery of proteins from polymeric blends
Degradable blend of polycaprolactone and crystallization modifier especially suitable for use in the controlled release of biologically active proteins
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7163694 |
Bioerodible poly(ortho esters) from dioxane-based di(ketene acetals), and block copolymers containing them
Bioerodible poly(ortho esters) useful as orthopedic implants or vehicles for the sustained delivery of pharmaceutical, cosmetic and agricultural agents from dioxane-based di(ketene acetals). Block...
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7101928 |
Polymeric thickeners for oil-containing compositions
Novel thickeners for oil-containing compositions are crystalline polymers, preferably side chain crystalline polymers, which (a) have a crystalline melting point, T p , and an onset of melting...
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7060734 |
Pharmaceutical coating composition and method of use
A composition is disclosed comprising a polymer and a surfactant in a solvent exhibiting a common solubility for the polymer and the surfactant. The composition provides a dosage form for...
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6870012 |
Chain-extended peo/ppo/peo block copolymer, optionally with polyester blocks, combined with cellular or bioactive material
A composition exhibiting reverse thermal gellation properties comprises a block polymer having the structure:
{[A n (BCB)A n ]} m...
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6852825 |
Polyester urethanes
The present invention relates to polyester urethanes comprising polypentadecalactone segments. These polyester urethanes do show good properties which may be adjusted in a controlled manner. In...
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6641800 |
Pressurized aerosol compositions comprising powdered medicament dispersed in hydrofluoroalkane
Pressurized aerosol composition for administration by inhalation comprising a liquefied hydrofluoroalkane, a powdered medicament dispersed therein, and a suspending agent comprising a polymer...
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6627600 |
Compressed microparticles for dry injection
The invention relates to a pharmaceutical implant for controllably releasing a drug in a subject and methods for manufacturing and administering the implant. The implant is made of associated...
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6613315 |
Cosmetic composition comprising at least one nonionic amphiphilic associative polyurethane and at least one nonionic polymer with fatty chains
The invention concerns cosmetic compositions containing, in a cosmetically acceptable medium, as thickening system: (A) at least a non-ionic associative polyurethane and (B) at least a non-ionic...
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6583178 |
Antibacterial liquid dish cleaning compositions having improved viscosity
An antibacterial liquid dish cleaning composition with desirable cleansing properties comprising a C 8-18 ethoxylated alkyl ether sulfate, two anionic surfactant, a betaine surfactant, a hydroxy...
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6582683 |
Dermal barrier composition
Disclosed is a dermal barrier composition which contains a hydrophilic polymer emulsion and a hydrophobic polymer emulsion. The dermal barrier composition is moisture activated, and remains inert...
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6488965 |
Synergistic antimicrobial preparations containing chlorite and hydrogen peroxide
Antimicrobial/pharmaceutical preparations (e.g., solutions, gels, ointments, creams, sustained release preparations, etc.) which comprise chlorite (e.g., a metal salt of a chlorite) in combination...
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6436425 |
Method and non-gelling composition for inhibiting post-surgical adhesions
Non-gelling polyoxyalkylene compositions, and methods of their use for inhibiting surgical adhesion formation/reformation in mammals are disclosed. The useful non-gelling compositions preferably...
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6395284 |
Immobilization of vitamin A acid by cationic polyelectrolytes
Mesomorphic complexes of vitamin A acid and cationic polyelectrolytes, their preparation and use. The cationic polyelectrolyte, for example PDADMAC, PM4VP, poly (ionene-6,3), polyethyleneimine or a...
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6391326 |
Stable emulsions, preparation methods and applications
The invention concerns stable emulsions, a method for preparing said emulsions and the elastomer films containing them. Said stable emulsions of at least one chemical substance x in an elastomer...
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6387391 |
Bioresorbable polymeric clayey and sticky substance
This invention provides a claycy and sticky substance as a new biomaterial that cannot be found in the current medical field, which is bioresorbable, shows tackiness, plasticity and shape holding...
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6379702 |
Gels formed by the interaction of polyvinylpyrrolidone with chitosan derivatives
A dermatologically-compatible composition comprising a hydrophilic gel which comprises a blend of a chitosan and a hydrophilic poly(N-vinyl lactam) having a K value of less than 60.
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6353030 |
Relating to organic compounds
A polylactide in a purified state, which meets the requirements of the color strengths of reference solutions B 2 -B 9 of the brown color test of the European Pharmacopoeia, 2nd Edition (1980)...
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6340464 |
Adjuvants for vaccines
Vaccine adjuvants comprising a liquid medium contain polymers with anionic constitutive repeating units and hydrophobic constitutive repeating units. Advantageously, the adjuvants are aqueous...
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6262127 |
Polymeric matrices and their uses in pharmaceutical compositions
This invention provides pharmaceutical compositions comprising polymeric matrices, especially those comprising IL-6 as an active ingredient. Specific novel poly(ethylene carbomate) polymers are...
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6261544 |
Poly(hydroxy acid)/polymer conjugates for skin applications
A method for alleviating the symptoms of a cosmetic or dermatologic skin condition is described. An effective amount of a poly(hydroxy acid)/polymer conjugate in a pharmaceutically or cosmetically...
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6251416 |
Water-based microemulsion of a pyrethroid
A clear, one-phase, efficacious aqueous microemulsion of an agriculturally active pyrethroid insecticide for delivery at a high loading of active is provided herein which is free of nonylphenol...
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6214366 |
Clearance and inhibition of conformationally altered proteins
The present invention provides a method of arresting, preventing and/or reversing the impairment of central and peripheral nervous system function comprising reducing insoluble protein deposit...
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6136334 |
Medical uses of in situ formed gels
Balanced pH, hyperosmotic, hypoosmotic, or isoosmotic gels are ideal vehicles for drug delivery. They are especially suited for topical body cavity or injection application of drugs or diagnostic...
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6107344 |
Aqueous germicidal film forming composition for applying to teats of dairy cows
Aqueous film forming compositions are disclosed that are to be applied to the teats of dairy animals to form a protective film on the teats. The protective film may be applied as a dip or spray....
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6042820 |
Biodegradable copolymer containing α-hydroxy acid and α-amino acid units
Copolymers designed for use as particulate carriers containing functionalizable amino subunits for coupling with targeting ligand are described. The copolymers are polyesters composed of α-hydroxy...
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5955509 |
pH dependent polymer micelles
The present invention relates to the use of poly(vinyl N-heterocycle)-block-poly(alkylene oxide) copolymers in micelle containing pharmaceutical formulations. The copolymers advantageously respond...
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5879688 |
Hydroxy-acid cosmetics
A method for alleviating the symptoms of a cosmetic or dermatologic skin condition is described. An effective amount of a poly(hydroxy acid)/polymer conjugate in a pharmaceutically or cosmetically...
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5840319 |
Biological agent compositions
Novel pharmaceutical compositions comprising a chemotherapeutic agent and a polyether block copolymer, and methods of treatment using the compositions.
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5711958 |
Methods for reducing or eliminating post-surgical adhesion formation
The present invention relates to a method for reducing adhesions associated with post-operative surgery. The present method comprises administering or affixing a polymeric composition comprising...
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5607686 |
Polymeric composition
A polymeric composition for use in medicine includes a hydrophobic bioabsorbable polymer admixed with a hydrophilic liquid polymer wherein the polymeric composition undergoes macroscopic phase...
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5565209 |
Adjuvant mixture
According to the present invention oil-free vaccines are provided which contain polyoxypropylene-polyoxyethylene polyols as well as an acrylic acid polymer as adjuvating constituents. These...
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5527524 |
Dense star polymer conjugates
Dense star polymer conjugates which are composed of at least one dendrimer in association with at least one unit of a carried agricultural, pharmaceutical, or other material have been prepared....
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5417981 |
Thermoplastic polymer composition and medical devices made of the same
A thermoplastic polymer composition containing a protease inhibiting substance and medical devices entirely or partly made of the thermoplastic polymer composition. Various medical devices having a...
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5405877 |
Cyclic imide thione activated polyalkylene oxides
Water-soluble cyclic imide thione activated polyalkylene oxides having improved hydrolytic stability are disclosed. Methods of forming and conjugating the activated polyalkylene oxides with...
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5360615 |
Solvent system enhancing the solubility of pharmaceuticals for encapsulation
This invention relates to a solvent system for enhancing the solubility of an acidic, basic, or amphoteric pharmaceutical agent to produce a highly concentrated solution suitable for softgel...
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5340591 |
Method of producing a solid dispersion of the sparingly water-soluble drug, nilvadipine
A solid dispersion and a method of producing a solid dispersion of a sparingly water-soluble drug characterized by mixing the sparingly water-soluble drug and a water-soluble polymer at a...
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5266581 |
Solid composition containing dihydropyridine, PVP and PVPP
A solid, rapidly absorbable composition by weight consisting of 1 part by weight of nimodipine, 0.01 to 1.5 parts of polyvinylpyrrolidone with an average molecular weight of 15,000 to 50,000 and 1...
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5174995 |
Topical drug release system
A topical composition containing a dissolved drug or the like (e.g. hydrocortisone acetate) preferably in saturated solution, and a solubilizer (e.g. propylene glycol), and preferably water and an...
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5169623 |
Conditioning hair care compositions
What is provided herein are conditioning hair care compositions comprising (a) a stabilized silicone product obtained by in situ polymerization of a water-soluble vinyl monomer, preferably...
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5169622 |
Hair and skin care compositions containing discrete microdroplets of an oil in water stabilized by in situ copolymerization of a water-soluble vinyl monomer and a water-soluble acryl comonomer
What is provided herein are hair and skin care compositions containing discrete microdroplets of an oil in water stabilized by in situ polymerization of a water-soluble vinyl monomer and a...
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5154926 |
Acetaminophen or phenobarbital syrup composition
The present invention relates to a syrup composition characterized in that the composition contains phenobarbital or acetaminophen, a polyhydric alcohol and/or a polymer of a polyhydric alcohol,...
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5130140 |
Method of making direct dry compressible acetaminophen composition
This invention relates to an analgesic composition and more particularly, to a directly dry compressible composition comprising at least about 70% by dry weight of the composition of acetaminophen...
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5130121 |
Skin care compositions containing discrete microdroplets of an oil in water stabilized by in situ polymerization of water-soluble vinyl monomer
What is provided herein are skin care compositions containing discrete microdroplets of an oil in water stabilized by in situ polymerization of a water-soluble vinyl monomer. The discrete...
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5124151 |
Drug delivery by injection with thermo-irreversible gels
Balanced pH, thermo-irreversible gels are ideal vehicles for drug injection into the body of a mammal.
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5112604 |
Oral suspension formulation
An aqueous suspension for oral administration of a drug, which suspension is storage stable for a prolonged period and maintains the drug in suspension during such period.
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5071644 |
Topical drug delivery with thermo-irreversible gels
Balanced pH, thermo-irreversible gels are ideal vehicles for drug delivery to the skin of a mammal.
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5035884 |
Methylene pyrrolidone copolymers for contact lens and pharmaceutical preparations
A new series of copolymers which are useful as coatings for solid dosage forms, for transdermal devices, for wound dressing materials, and for contact lenses. Also disclosed are methods for...
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5030448 |
Method of delivering drugs to damaged or diseased tissue
In accordance with the present invention, a method is provided for efficiently delivering drugs to damaged tissue. The method comprises administering an admixture of an effective concentration of a...
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4946931 |
Polymers containing carboxy-ortho ester and ortho ester linkages
Polymers are provided that are useful for making biodegradable sustained release agent dispensers and which contain at least one of the following mer units (I) and (II) ##STR1## wherein X is a...
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