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7951401 |
Stabilised solid drug dispersions in an organic carrier and a process for preparing the same
New solid drug dispersions are described in which a drug is present in amorphous form and dispersed within the particles of an organic carrier selected from cross-linked polymers and/or complexing...
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7919562 |
Preparation of supramolecular polymers containing sequence-selective hydrogen bonding subunits in their backbone which form double helices
The present invention relates to supramolecular polymers containing sequence-selective hydrogen bonding subunits in their backbone which form double helices. The invention allows for tuning of the...
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7897224 |
Bioabsorbable polymeric composition for a medical device
A biodegradable and biocompatible nontoxic polymeric composition is provided which includes a base material such as a crystallizable polymer, copolymer, or terpolymer, and a copolymer or terpolymer...
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7897698 |
Method of modifying a macromolecular system
The present application discloses a method of modifying a macromolecule, the method comprising the steps of (i) providing the macromolecule; (ii) providing a compound of the general formula (I):...
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7863388 |
Preparation of functionalized cationic polymers and their application in personal care
Water-soluble functionalized cationic copolymers obtainable by a process which comprises reacting a cationic base polymer which contains amino groups with at least one functional compound reactive...
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7846361 |
Bioabsorbable polymeric composition for a medical device
A biodegradable and biocompatible nontoxic polymeric composition is provided which includes a base material such as a crystallizable polymer, copolymer, or terpolymer, and a copolymer or terpolymer...
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7700659 |
Implantable devices formed of non-fouling methacrylate or acrylate polymers
Implantable devices formed of or coated with a material that includes a polymer having a non-fouling acrylate or methacrylate polymer are provided. The implantable device can be used for treating...
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7655735 |
Biodegradable multi-block polymeric composition capable of sol-gel transition and pharmaceutical composition comprising the same
The present invention relates to an ionic multi-block copolymer composition comprising tri-block copolymers having a polypropyleneoxide or polybutyleneoxide block positioned between two...
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7569643 |
Reverse thermal gellation polymer of chain-extended optional polyester-terminated PEO-PPO-PEO
The present invention relates to novel polymeric compositions based upon An(BCB)An polyester/polyether multi-blocks. Compositions according to the present invention exhibit unexpectedly exceptional...
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7560493 |
Cosmetic and/or dermatological composition containing at least one oxidation-sensitive hydrophilic active principle and at least one N-vinylimidazole polymer or copolymer
The invention relates to a composition for topical use containing, in a physiologically acceptable medium having an aqueous phase, at least one oxidation-sensitive hydrophilic active principle and...
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7550512 |
Medical polymers and uses thereof
The present invention provides a polyethylene glycol derivative having sugar residue-containing side chains and carboxyl group-containing side chains, and a method of preparing the same. The...
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7544348 |
Liquid formulations for the prevention and treatment of mucosal diseases and disorders
Stable, viscous, mucoadhesive aqueous compositions which are useful for the prevention and treatment of ulcerative, inflammatory, and/or erosive disorders of mucous membranes, especially mucositis.
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7189413 |
Drug delivery of proteins from polymeric blends
Degradable blend of polycaprolactone and crystallization modifier especially suitable for use in the controlled release of biologically active proteins
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7163694 |
Bioerodible poly(ortho esters) from dioxane-based di(ketene acetals), and block copolymers containing them
Bioerodible poly(ortho esters) useful as orthopedic implants or vehicles for the sustained delivery of pharmaceutical, cosmetic and agricultural agents from dioxane-based di(ketene acetals). Block...
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7101928 |
Polymeric thickeners for oil-containing compositions
Novel thickeners for oil-containing compositions are crystalline polymers, preferably side chain crystalline polymers, which (a) have a crystalline melting point, Tp, and an onset of melting...
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6870012 |
Chain-extended peo/ppo/peo block copolymer, optionally with polyester blocks, combined with cellular or bioactive material
A composition exhibiting reverse thermal gellation properties comprises a block polymer having the structure: {[An(BCB)An]}m wherein A is a polyester unit, B is a poly(ethylene oxide) unit, C is a...
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6852825 |
Polyester urethanes
The present invention relates to polyester urethanes comprising polypentadecalactone segments. These polyester urethanes do show good properties which may be adjusted in a controlled manner. In...
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6641800 |
Pressurized aerosol compositions comprising powdered medicament dispersed in hydrofluoroalkane
Pressurized aerosol composition for administration by inhalation comprising a liquefied hydrofluoroalkane, a powdered medicament dispersed therein, and a suspending agent comprising a polymer...
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6627600 |
Compressed microparticles for dry injection
The invention relates to a pharmaceutical implant for controllably releasing a drug in a subject and methods for manufacturing and administering the implant. The implant is made of associated...
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6613315 |
Cosmetic composition comprising at least one nonionic amphiphilic associative polyurethane and at least one nonionic polymer with fatty chains
The invention concerns cosmetic compositions containing, in a cosmetically acceptable medium, as thickening system: (A) at least a non-ionic associative polyurethane and (B) at least a non-ionic...
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6583178 |
Antibacterial liquid dish cleaning compositions having improved viscosity
An antibacterial liquid dish cleaning composition with desirable cleansing properties comprising a C8-18 ethoxylated alkyl ether sulfate, two anionic surfactant, a betaine surfactant, a hydroxy...
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6582683 |
Dermal barrier composition
Disclosed is a dermal barrier composition which contains a hydrophilic polymer emulsion and a hydrophobic polymer emulsion. The dermal barrier composition is moisture activated, and remains inert...
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6488965 |
Synergistic antimicrobial preparations containing chlorite and hydrogen peroxide
Antimicrobial/pharmaceutical preparations (e.g., solutions, gels, ointments, creams, sustained release preparations, etc.) which comprise chlorite (e.g., a metal salt of a chlorite) in combination...
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6436425 |
Method and non-gelling composition for inhibiting post-surgical adhesions
Non-gelling polyoxyalkylene compositions, and methods of their use for inhibiting surgical adhesion formation/reformation in mammals are disclosed. The useful non-gelling compositions preferably...
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6395284 |
Immobilization of vitamin A acid by cationic polyelectrolytes
Mesomorphic complexes of vitamin A acid and cationic polyelectrolytes, their preparation and use. The cationic polyelectrolyte, for example PDADMAC, PM4VP, poly (ionene-6,3), polyethyleneimine or a...
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6391326 |
Stable emulsions, preparation methods and applications
The invention concerns stable emulsions, a method for preparing said emulsions and the elastomer films containing them. Said stable emulsions of at least one chemical substance x in an elastomer...
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6387391 |
Bioresorbable polymeric clayey and sticky substance
This invention provides a claycy and sticky substance as a new biomaterial that cannot be found in the current medical field, which is bioresorbable, shows tackiness, plasticity and shape holding...
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6379702 |
Gels formed by the interaction of polyvinylpyrrolidone with chitosan derivatives
A dermatologically-compatible composition comprising a hydrophilic gel which comprises a blend of a chitosan and a hydrophilic poly(N-vinyl lactam) having a K value of less than 60.
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6353030 |
Relating to organic compounds
A polylactide in a purified state, which meets the requirements of the color strengths of reference solutions B2-B9 of the brown color test of the European Pharmacopoeia, 2nd Edition (1980) part I,...
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6340464 |
Adjuvants for vaccines
Vaccine adjuvants comprising a liquid medium contain polymers with anionic constitutive repeating units and hydrophobic constitutive repeating units. Advantageously, the adjuvants are aqueous...
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6261544 |
Poly(hydroxy acid)/polymer conjugates for skin applications
A method for alleviating the symptoms of a cosmetic or dermatologic skin condition is described. An effective amount of a poly(hydroxy acid)/polymer conjugate in a pharmaceutically or cosmetically...
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6262127 |
Polymeric matrices and their uses in pharmaceutical compositions
This invention provides pharmaceutical compositions comprising polymeric matrices, especially those comprising IL-6 as an active ingredient. Specific novel poly(ethylene carbomate) polymers are...
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6251416 |
Water-based microemulsion of a pyrethroid
A clear, one-phase, efficacious aqueous microemulsion of an agriculturally active pyrethroid insecticide for delivery at a high loading of active is provided herein which is free of nonylphenol...
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6214366 |
Clearance and inhibition of conformationally altered proteins
The present invention provides a method of arresting, preventing and/or reversing the impairment of central and peripheral nervous system function comprising reducing insoluble protein deposit...
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6136334 |
Medical uses of in situ formed gels
Balanced pH, hyperosmotic, hypoosmotic, or isoosmotic gels are ideal vehicles for drug delivery. They are especially suited for topical body cavity or injection application of drugs or diagnostic...
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6107344 |
Aqueous germicidal film forming composition for applying to teats of dairy cows
Aqueous film forming compositions are disclosed that are to be applied to the teats of dairy animals to form a protective film on the teats. The protective film may be applied as a dip or spray....
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6042820 |
Biodegradable copolymer containing α-hydroxy acid and α-amino acid units
Copolymers designed for use as particulate carriers containing functionalizable amino subunits for coupling with targeting ligand are described. The copolymers are polyesters composed of α-hydroxy ...
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5955509 |
pH dependent polymer micelles
The present invention relates to the use of poly(vinyl N-heterocycle)-block-poly(alkylene oxide) copolymers in micelle containing pharmaceutical formulations. The copolymers advantageously respond...
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5879688 |
Hydroxy-acid cosmetics
A method for alleviating the symptoms of a cosmetic or dermatologic skin condition is described. An effective amount of a poly(hydroxy acid)/polymer conjugate in a pharmaceutically or cosmetically...
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5840319 |
Biological agent compositions
Novel pharmaceutical compositions comprising a chemotherapeutic agent and a polyether block copolymer, and methods of treatment using the compositions.
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5711958 |
Methods for reducing or eliminating post-surgical adhesion formation
The present invention relates to a method for reducing adhesions associated with post-operative surgery. The present method comprises administering or affixing a polymeric composition comprising...
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5607686 |
Polymeric composition
A polymeric composition for use in medicine includes a hydrophobic bioabsorbable polymer admixed with a hydrophilic liquid polymer wherein the polymeric composition undergoes macroscopic phase...
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5565209 |
Adjuvant mixture
According to the present invention oil-free vaccines are provided which contain polyoxypropylene-polyoxyethylene polyols as well as an acrylic acid polymer as adjuvating constituents. These...
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5527524 |
Dense star polymer conjugates
Dense star polymer conjugates which are composed of at least one dendrimer in association with at least one unit of a carried agricultural, pharmaceutical, or other material have been prepared....
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5417981 |
Thermoplastic polymer composition and medical devices made of the same
A thermoplastic polymer composition containing a protease inhibiting substance and medical devices entirely or partly made of the thermoplastic polymer composition.Various medical devices having a...
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5405877 |
Cyclic imide thione activated polyalkylene oxides
Water-soluble cyclic imide thione activated polyalkylene oxides having improved hydrolytic stability are disclosed. Methods of forming and conjugating the activated polyalkylene oxides with...
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5360615 |
Solvent system enhancing the solubility of pharmaceuticals for encapsulation
This invention relates to a solvent system for enhancing the solubility of an acidic, basic, or amphoteric pharmaceutical agent to produce a highly concentrated solution suitable for softgel...
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5340591 |
Method of producing a solid dispersion of the sparingly water-soluble drug, nilvadipine
A solid dispersion and a method of producing a solid dispersion of a sparingly water-soluble drug characterized by mixing the sparingly water-soluble drug and a water-soluble polymer at a...
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5266581 |
Solid composition containing dihydropyridine, PVP and PVPP
A solid, rapidly absorbable composition by weight consisting of 1 part by weight of nimodipine, 0.01 to 1.5 parts of polyvinylpyrrolidone with an average molecular weight of 15,000 to 50,000 and 1...
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5174995 |
Topical drug release system
A topical composition containing a dissolved drug or the like (e.g. hydrocortisone acetate) preferably in saturated solution, and a solubilizer (e.g. propylene glycol), and preferably water and an...
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