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7629388 |
Synthesis and characterization of biodegradable cationic poly(propylene fumarate-co-ethylene glycol) copolymer hydrogels modified with agmatine for enhanced cell adhesion
A cross-linkable monomer comprises a fumaric acid functional group having a first end and a second end, a first spacer group affixed to said first end and comprising at least repeating unit, a...
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7544348 |
Liquid formulations for the prevention and treatment of mucosal diseases and disorders
Stable, viscous, mucoadhesive aqueous compositions which are useful for the prevention and treatment of ulcerative, inflammatory, and/or erosive disorders of mucous membranes, especially mucositis.
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7517914 |
Controlled degradation materials for therapeutic agent delivery
According to an aspect of the present invention, polymeric release regions are provided, which contain one or more partially biodegradable progenitor polymers and which control the release of one...
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7491749 |
At least one polyamide polymer in a cosmetic composition comprising at least one solid substance having a melting point of 45 degrees C. or greater
Cosmetic compositions comprising at least one structuring polymer chosen from polymers of following formula (I):
in which n denotes a number of amide units, such that the number of ester groups...
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7442721 |
Durable biocompatible controlled drug release polymeric coatings for medical devices
Disclosed herein are biocompatible durable controlled drug releasing polymeric coatings for medical devices. The drug release rates of the polymers are controlled by adjusting monomer ratios and...
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7429619 |
Polyacrylic film forming compositions
Water soluble, gelatin-free dip coatings for substrates comprising an acrylic film former; a paraben plasticizer; and a secondary plasticizer such as polyvinylpyrrolidone, polyethylene glycol 300,...
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7419685 |
Process for producing solid dosage forms
Solid dosage forms containing at least one polymer binder, at least one active ingredient and, where appropriate, conventional additives, wherein a physiologically tolerated, water-swellable graft...
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7388032 |
Sustained release compositions, process for producing the same and utilization thereof
A sustained-release composition containing a hydroxynaphthoic acid salt of a biologically active substance and a biodegradable polymer, a method of its production, and a pharmaceutical composition...
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7384984 |
Reactive hydrophilic oligomers
Hydrophilic compositions are described, which are prepared from a first component oligomer containing pendent hydrophilic groups and pendent reactive functional groups capable of reaction at...
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7374778 |
Enhanced transport using membrane disruptive agents
Compositions and methods for transport or release of therapeutic and diagnostic agents or metabolites or other analytes from cells, compartments within cells, or through cell layers or barriers are...
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7342047 |
Crosslinkable hydrophilic materials from reactive oligomers having pendent unsaturated groups
The present invention provides cross linkable compositions useful in the preparation of hydrophilic gels, and are prepared from obligers having pendent hydrophilic ploy(alkenylene oxide) groups,...
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7314636 |
Biodegradable injectable implants containing glycolic acid
This invention is directed to the field of medical implants, and more specifically to biodegradable injectable implants and their methods of manufacture and use. The injectable implants disclosed...
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7265157 |
Sustained release compositions, process for producing the same and use thereof
Sustained release compositions containing a physiologically active substance or its salt, hydroxynaphthoic acid or its salt and a lactic acid-glycolic polymer or its salt, wherein the product of...
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7255870 |
Composition containing a semicrystalline polymer, uses thereof, and method for making
A composition containing an aqueous phase dispersed in an oily phase, at least one emulsifier with an HLB value ranging from 1 to 8, at least one organic powder, and, in the oily phase at least one...
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7189414 |
Controlled release oral drug delivery system
The invention relates to synchronous drug delivery composition comprising a polymeric matrix which comprises hydrogel blended with a hydrophobic polymer, so as to form an erodible matrix, a drug,...
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7125546 |
Polymeric micelle containing cisplatin enclosed therein and use thereof
Provided is a complex comprising cisplatin encapsulated therein in a form in which a chlorine ion thereof is ligand-exchanged with a carboxyl anion of a block copolymer comprising poly(ethylene...
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7118761 |
Method for producing a silver-containing wound care device
Wound care devices having a topically applied silver-based antimicrobial finish are provided. The finish comprises at least one silver ion-containing compound and at least one binder compound. The...
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7101840 |
Polymeric drug formulations
A method of forming a polymeric drug formulation in which a water-soluble drug is blended with a water-insoluble tissue-compatible polymer that is miscible in the solid phase with the drug, and...
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7071212 |
N-(4-carbamimidoyl-phenyl)-glycine derivatives
The invention is concerned with novel N-(4-carbamimidoyl-phenyl)-glycine derivatives of the formula:
wherein R 1 , E, X 1 to X 4 and G 1 and G 2 are as defined in the description and the...
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6998128 |
Controlled release composite
A composite is disclosed having a controlled rate of dissolution. The composite includes (a) a first region that includes a first composition that includes calcium sulfate, the first region...
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6953587 |
Process for making a water-soluble foam component
The present invention relates to a process for preparing a water-soluble foam matrix which is capable of delivering an active ingredient and articles of manufacture comprising said foam matrix,...
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6911209 |
Method of treating sick sinus syndrome with levosimendan
Levosimendan, or (−)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)p
henyl]hydrazono]propanedinitrile, which has been previously suggested for the treatment of congestive heart failure is...
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6890522 |
Cosmetic and personal care compositions
Cosmetic or personal care compositions, such as for styling hair, comprise a thermoplastic elastomer which is a block copolymer comprising a core polymer having a backbone comprising at least a...
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6866860 |
Cationic alkyd polyesters for medical applications
The present invention is directed to medical devices or pharmaceutical composition, each containing a synthetic, biodegradable, biocompatible polymer that is the reaction product of a polybasic...
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6867181 |
Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
A method of spherifying a sustained release ionic conjugate which contains a free carboxyl group-containing polymer and a free amino group-containing drug which are ionically bonded to each other.
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6858673 |
Composition for hydrogel, hydrogel and use thereof
A composition for hydrogels which comprises (A1) a copolymer which comprises 25 to 97 mol % of unit (a) derived from a compound represented by formula (1) and 3 to 75 mol % of unit (b) derived from...
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6824792 |
Bioadhesive composition
This invention relates to a method of producing a bioadhesive composition comprising the steps of preparing a solution of a solvent and a polymer mixture wherein the polymer mixture comprises at...
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6825234 |
Compositions and methods for amelioration of human female sexual dysfunction
The invention provides compositions and methods suitable for ameliorating female sexual dysfunction, and in particular, female sexual arousal disorder. In one embodiment, the invention provides a...
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6818207 |
Artificial nail compositions and related method
The invention comprises a polymerizable monomer composition for application to the nail surface and polymerization thereon to yield an artificial nail structure, comprising at least one...
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6756407 |
Method and compositions for the treatment or amelioration of female sexual dysfunction
The present invention provide a method of treating sexual dysfunction in a female, including the vasculogenic symptoms of delayed vaginal engorgement, diminished vaginal lubrication, pain or...
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6756059 |
Topical composition, topical composition precursor, and methods for manufacturing and using
A tropical composition is provided. The topical composition can be prepared by diluting a topical composition precursor with water and adding additional components, if desired. The topical...
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6726916 |
Thickened film-forming composition
A thickened film-forming composition comprising a film-forming polymer and, as thickener, a polysaccharide alkyl ether formed of units containing at least two different saccharide rings, each unit...
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6706666 |
Enhancer composition for agricultural chemicals and agricultural chemical composition
An enhancer composition for agricultural chemicals which can enhance the effectiveness of an agricultural chemical without causing any phytotoxicity to various crops, which comprises at least one...
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6699493 |
Method for reducing or preventing transplant rejection in the eye and intraocular implants for use therefor
Methods for reducing or preventing transplant rejection in the eye of an individual are described, comprising: a) performing an ocular transplant procedure; and b) implanting in the eye a...
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6646011 |
Insect repellant compositions
The present invention relates to insect repellant compositions containing, based upon the total weight of the composition, from about 6 to about 30 percent by weight of insect repellant active...
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6641800 |
Pressurized aerosol compositions comprising powdered medicament dispersed in hydrofluoroalkane
Pressurized aerosol composition for administration by inhalation comprising a liquefied hydrofluoroalkane, a powdered medicament dispersed therein, and a suspending agent comprising a polymer...
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6641834 |
Compositions containing alpha-2-adrenergic agonist components
Compositions useful for improving effectiveness of alpha-2-adrenergic agonist components include carrier components, alpha-2-adrenergic agonist components, solubility enhancing components which aid...
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6627210 |
Compositions containing α-2-adrenergic agonist components
Compositions useful for improving effectiveness of alpha-2-adrenergic agonist components include carrier components, alpha-2-adrenergic agonist components, solubility enhancing components which aid...
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6613315 |
Cosmetic composition comprising at least one nonionic amphiphilic associative polyurethane and at least one nonionic polymer with fatty chains
The invention concerns cosmetic compositions containing, in a cosmetically acceptable medium, as thickening system: (A) at least a non-ionic associative polyurethane and (B) at least a non-ionic...
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6607752 |
Method for the anhydrous loading of nicotine onto ion exchange resins
An environmentally friendly method of loading nicotine onto cation exchange resins under anhydrous conditions is described. The method eliminates many of the processing problems that are associated...
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6593317 |
Progestin therapy for maintaining amenorrhea
The present invention teaches that daily, cyclical vaginal delivery of progestin may be used to provide regular, predictable withdrawal bleeding during hormone replacement therapy. The present...
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6582683 |
Dermal barrier composition
Disclosed is a dermal barrier composition which contains a hydrophilic polymer emulsion and a hydrophobic polymer emulsion. The dermal barrier composition is moisture activated, and remains inert...
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6562873 |
Compositions containing therapeutically active components having enhanced solubility
Compositions which include therapeutically active components, solubility enhancing components other than cyclodextrins, and oxy-chloro components, wherein the oxy-chloro components are...
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6562331 |
Mating disruption methods for the control of insect pests
A mating disruption method for the control of insect pests comprises releasing a sex pheromone in a field wherein an adsorption of the sex pheromone to a soil in the field is decreased.
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6555096 |
Nail enamel composition containing a urea-modified thixotropic agent in a solvent system
A nail enamel composition which contains, in a cosmetically acceptable solvent system containing diacetone alcohol and at least one additional solvent chosen from C 1 -C 6 alkyl acetates and C 1...
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6538026 |
Compositions useful for remodeling body spaces
A composition comprising of a monomer component comprised of at least one alkyl cyanoacrylate and at least one inhibitor, and a second component comprised of a resultant aggregate structure formed...
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6521251 |
Methods for treating burns on mammalian skin to reduce the risk of infection and to minimize fluid loss
Disclosed are methods for treating burns on mammalian skin to reduce the risk of infection and to minimize fluid loss. Specifically, the methods of this invention involve the in situ formation of a...
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6514517 |
Antimicrobial coatings for medical devices
The present invention is directed to compositions containing an acid precursor in amounts effective to inhibit microbial attachment and growth on a surface of a medical device having the...
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6509031 |
System for polymerizing collagen and collagen composites in situ for a tissue compatible wound sealant, delivery vehicle, binding agent and/or chemically modifiable matrix
This invention relates to materials and methods for crosslinking, in situ, proteins, including collagen, with peroxidase, including horseradish peroxidase, to from biocompatible semi-solid gels...
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6488965 |
Synergistic antimicrobial preparations containing chlorite and hydrogen peroxide
Antimicrobial/pharmaceutical preparations (e.g., solutions, gels, ointments, creams, sustained release preparations, etc.) which comprise chlorite (e.g., a metal salt of a chlorite) in combination...
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