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5972326 |
Controlled release of pharmaceuticals in the anterior chamber of the eye
The present invention relates to compositions which maintain the structural integrity of the anterior chamber of the eye during ophthalmologic surgery, thereby protecting the tissues that form and...
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5968546 |
Keratinocyte culture from precursor cells
The present invention relates to the treatment of skin defect by organotypically cultured autologous keratinocytes isolated from the outer root sheath of hair follicles. Methods for primary as well...
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5965161 |
Extruded multi-particulates
A unit dose sustained-release oral dosage form containing a plurality of melt-extruded particles, each consisting essentially of a therapeutically active agent, one or more retardants, and an...
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5962520 |
Hydrolytically unstable, biocompatible polymer
A hydrolytically unstable, biocompatible polymer capable of carrying and releasing a pharmaceutical compound when introduced into physiological media. In a preferred embodiment, the polymer...
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5958452 |
Extruded orally administrable opioid formulations
Bioavailable sustained release oral opioid analgesic dosage forms, comprising a plurality of multiparticulates produced via melt extrusion techniques are disclosed.
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5955112 |
Non-stinging styptic pencil
A non-stinging styptic composition in the form of a water soluble resin coated cast pencil, for stopping bleeding from cuts and nicks received during shaving. The composition comprises aluminum...
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5942244 |
Local oral herbal slow release tablets
A tablet for the local and slow release of herbal medication into the oral cavity of a subject. Also provided is a method of making the tablet and a method of using the tablet. The tablet includes...
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5942242 |
Medicaments for nasal administration
A medicament for nasal administration to be used for disease prevention or treatment comprising a vaccine or a pharmacologically active peptide compounded with an ion exchange resin or adsorbent...
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5939358 |
Compatibility agent and method
A compatibility agent comprising a block copolymer of ethylene oxide and propylene oxide comprising about 30-80% ethylene oxide and about 20-70% propylene oxide which has been found useful for...
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5932205 |
Biochemical contact lens for treating photoablated corneal tissue
Methods for treating photoablated corneal tissue are described. The methods include contacting photoablated corneal tissue with a contact lens which includes an amniotic composition such that...
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5928655 |
Compact solid gel containing water
A compact solid gel is described containing water, that consists of water in a concentration ranging from 15% to 90%, thermoreversible polysaccharides in a concentration ranging from 0.3% to 4%,...
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5922357 |
Polymer microspheres and a method of production thereof
The invention relates to microspheres which are suitable for biomedical uses which have a diameter in the range of 10 nm to 2 mm and which comprise a substantially spherical core particle of a...
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5922776 |
Sustained release, transparent biocidal compositions
A composition for retarding bacterial, fungal and viral contamination and mold growth containing an acid releasing polymer, a hydrophilic material, and chlorite anions. Each component of the...
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5919484 |
Controlled release, drug-delivery tableted composition including a polymer of a vinyl amide, (meth)acrylic acid, a long chain alkyl (meth)acrylate and a lower alkyl (meth)acrylate
A controlled release, drug-delivery tableted composition comprising, by weight, an uncrosslinked or crosslinked polymer of (a) about 5-40% of a vinyl amide, (b) about 10-70% of (meth)acrylic acid,...
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5919481 |
Fill material for soft gelatin pharmaceutical dosage form
The present invention relates to a substantially translucent, semi-solid fill material for a soft gelatin capsule containing a therapeutically effective amount of a pharmaceutical dissolved or...
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5916584 |
Controlled release container with core and outer shell
A controlled release container includes an outer shell and a separately produced core that comprises at least one bioactive molecule. At least a portion of the outer shell comprises a biodegradable...
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5916590 |
Soft gelatin pharmaceutical dosage form
The present invention relates to a substantially translucent, gel fill material for a soft gelatin capsule containing a therapeutically effective amount of a pharmaceutical dissolved or suspended...
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5910312 |
Acne treatment composition with vasoconstrictor
The acne treatment composition of the present invention includes an effective amount of acne treatment medication selected from the group consisting of benzoyl peroxide and salicylic acid, and...
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5908619 |
Hydroalcoholic compositions thickened using surfactant/polymer complexes
Hydroalcoholic compositions and methods of preparation are provided. The composition includes a lower alcohol and water in a weight ratio of at least about 20:80 and a thickener system comprising a...
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5908636 |
Fill material for soft gelatin pharmaceutical dosage form containing an antiflatulent
The present invention relates to a semi-solid fill material for a soft gelatin capsule containing a therapeutically effective amount of an antiflatulent. The semi-solid is sufficiently viscous so...
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5908633 |
Bioartificial hormone releasing device
A device for the effective release of hormones wherein a matrix containing a hormone producing cellular moiety is encapsulated with a non-immunogenic polymeric material of poly-para-xylyene having...
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5905072 |
Adjuvants for systemic fungicides, fungicidal compositions which contain them and their use
Adjuvants for systemic fungicides in the form of a stable microemulsion comprise water, a mixture of methyl esters of fatty acids obtained by the transesterification of vegetable oils, an anionic...
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5902606 |
Solid and liquid solutions of sparingly water-soluble medicinal substances
Sparingly water-soluble active compounds, for example medicinal substances, are converted into the dissolved (molecularly disperse) state by dissolving them in a hydrophilic peptide having a...
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5902589 |
Method for treating hydratable polymers, compositions obtained therefrom, and methods of using same
Aqueous solutions of hydratable polymers are prepared by hydrating a hydratable polymer in water without agitation sufficient to shear the molecular structure of the polymer thereby maintaining...
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5902603 |
Polyurethane hydrogel drug reservoirs for use in transdermal drug delivery systems, and associated methods of manufacture and use
High capacity drug reservoirs are provided for incorporation into transdermal drug delivery systems. The drug reservoirs are hydrogels formulated from polyurethanes crosslinked with diisocyanate...
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5900233 |
Epichlorohydrin and 1-(3-aminopropyl) imidazole copolymer and its use in treating irritable bowel syndrome
An anion-binding hydrophilic epichlorohydrin and 1-(3-aminopropyl)imidazole copolymeric bile acid sequestrant, pharmaceutical compositions thereof, and use thereof in the treatment of ailments or...
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5897874 |
Expulsion of material from a delivery device
A delivery device for delivering an active substance to a patient at a predetermined time after administration comprises a male hydrogel plug engaged in the neck of a female body. An expandable...
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5891456 |
Glyceryl monosterate based biodegradable implants for site-specific delivery of drugs
A method to administer a drug locally to a subject in which biodegradable dosage forms that contain the drug are implanted at a localized site beneath the skin of the subject whereupon the dosage...
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5891458 |
Bioerodible device for administering active ingredients
The invention relates to a muco-adherent, soluble device for administering active ingredients, a method of using said device, and an improved method of manufacturing said device using a continuous,...
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5888528 |
Sustained release biocidal powders
A powder for sustained release of a gas including a hydrophilic core, a hydrophobic layer on an outer surface of the hydrophilic core, and particles in contact with the hydrophobic layer. The...
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5888534 |
Controlled release of drugs delivered by sublingual or buccal administration
A composition providing a relatively slow release of water-soluble drugs, such as apomorphine, for delivery via the sublingual or buccal routes.
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5885590 |
Oral vaccines comprising multiple emulsions and methods of preparation
The present invention relates to water-in-oil and water-in-oil-in-water multiple emulsions and methods of preparation which overcome many of the limitations of previous emulsions and are superior...
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5882689 |
Control of soilborne fungi in cultivated crops
This invention provides a method for controlling soilborne fungal disease in cultivated field plants such as a peanut crop. Field crop soil is treated with a free-flowing granular fungicide...
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5883045 |
Method for the treatment of plants with agrochemical tablet compositions
Novel method for applying agrochemicals to plants, which method consists in attaching to the surface of the plants tablets comprising at least one agrochemically active compound and at least...
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5879706 |
Valaciclovir tablets containing colloidal silicon dioxide
A tablet comprising at least 50% w/w valaciclovir and 0.05 to 3% w/w colloidal silicon dioxide in which the valaciclovir is present within granules of the tablets and the silicon dioxide, a...
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5879662 |
Oral echo contrast medium for ultrasonic diagnosis
An oral contrast agent for use in ultrasound diagnostic procedures in human medicine to create an image of the gastrointestinal tract. The oral contrast agent contains at least one thickening agent...
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5879688 |
Hydroxy-acid cosmetics
A method for alleviating the symptoms of a cosmetic or dermatologic skin condition is described. An effective amount of a poly(hydroxy acid)/polymer conjugate in a pharmaceutically or cosmetically...
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5869074 |
Pesticidal compositions
The pesticidal composition of the invention comprises dichlorvos and chlorpyrifos. The composition is prepared by combining the components together and then subjecting the mixture to microwave...
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5863555 |
Buccal delivery of glucagon-like insulinotropic peptides
Drug delivery systems and methods for administering a glucagon-like insulinotropic peptide to the buccal mucosa for transmucosal drug delivery are described. The drug delivery systems comprise a...
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5861172 |
Pharmaceutical formulations of compacted granulates of β-lactam antibiotics
The present invention discloses tablet formulations, produced by dry roller compaction comprising compacted granulates of a mixture of a medicament and an intra-granular disintegrant. The...
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5859069 |
Gelatinous external skin treatment composition
A gelatinous external skin treatment composition comprising (1) spherical powder of organopolysiloxane elastomer having an average particle size of 1.0 to 15.0 μm, (2) silicone oil and (3)...
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5858345 |
In vivo polymerizable ophthalmic compositions
Ophthalmic compositions containing biocompatible, bioadhesive polymerizable amphipathic mesophase materials useful for repairing retinal tissue tears or retinal detachments are disclosed. In one...
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5859161 |
Silicone phosphate esters as irritation mitigants
The present invention relates to a series of novel silicone phosphate esters which mitigate eye and skin irritation when used in synergistic combinations with fatty alcohol sulfates and fatty...
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5855900 |
Supramolecular-structured biodegradable polymeric assembly for drug delivery
This invention provides as a novel drug carrier into a living body a highly water-soluble polymer that can carry and release a drug at a desired rate and a supramolecular-structured biodegradable...
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5851277 |
Preparation whose coloring depends on the viewing angle
The invention relates to cosmetic or pharmaceutical preparations comprising pigments whose coloring depends on the viewing angle and comprising additives which are customary for cosmetic or...
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5849266 |
Dental composition for hypersensitive teeth
The invention relates to an oral composition for the treatment and prevention of dental hypersensitivity comprising an anti-hypersensitivity agent embedded in a sustained release carrier such as a...
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5846564 |
Effervescent composition containing iodinated polyvinylpyrrolidone, and use thereof for disinfection
Effervescent composition comprising in synergetic quantities: iodinated polyvinylpyrrolidone (IPVP) at least one effervescent agent, and at least one disintegrating agent. It may be presented in...
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5847023 |
Thermal irreversible gel corneal contact lens formed in situ
Balanced pH, thermo-irreversible gels comprising a polyoxyalkylene compound and an ionic polysaccharide are ideal materials for the formation of a protective contact lens over the cornea of the eye...
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5847046 |
Biodegradable bone cement
A surgical bonding material includes a continuous phase and a discontinuous phase. The continuous phase is formed from a polymerizable liquid. The discontinuous phase includes particles of...
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5840329 |
Pulsatile drug delivery system
A pulsatile drug delivery system comprising of a plurality of particles is able to deliver drug in any desired patterns. A plurality of particles with multi-layer core capable of short-pulse...
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