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6177094 Bioabsorbable blends and coating composition containing same  
A bioabsorbable blend is provided which comprises the reaction product of 1) a bioabsorbable copolymer obtained by polymerizing a major amount of epsilon-caprolactone and a minor amount of at least...
6177102 Once daily analgesic tablet  
An analgesic controlled release dosage form containing: (a) 40-80 weight percent of an analgesic; (b) 10-30 weight percent of a pharmaceutically acceptable filler; and (c) 10-30 weight percent of a...
6168805 Aqueous process for manufacturing paroxetine solid dispersions  
A process for preparing solid, amorphous paroxetine comprising: (A) mixing paroxetine free base or a pharmaceutically acceptable paroxetine salt with water and pharmaceutically acceptable polymer;...
6165482 Gastrointestinal drug composition  
A composition for treating the gastrointestinal tract comprising a porous insoluble absorbent in which the pores of the insoluble absorbent are clogged by a coating material which causes the...
6156348 Methods and compositions for enhancing the bioadhesive properties of polymers using organic excipients  
Methods and compositions are provided for enhancing the bioadhesive properties of polymers used in drug delivery systems. The bioadhesive properties of a polymer are enhanced by incorporating an...
6149922 Vaccine adjuvant and vaccine  
The present invention includes novel polyoxyethylene/polyoxypropylene block copolymers as well as methods for making the block copolymers. The block copolymers are high molecular weight molecules...
6150410 pH independent extended release pharmaceutical formulation  
Pharmaceutical formulations of acidic pharmacologic agents which demonstrate improved uniformity of release over the wide range of pH values encountered between the stomach and intestinal tract...
6149940 Tablet with controlled release of alfuzosine chlorhydrate  
Pharmaceutical tablet which consists of: a) a first layer having the property of swelling considerably and quickly on contact with aqueous biological fluids, the first layer being produced by...
6143315 Biochemical contact lens for treating injured corneal tissue  
Methods for treating injured corneal tissue are described. The methods include contacting injured corneal tissue with a contact lens which includes an amniotic composition such that scarring of the...
6129931 Controlled-release, drug-delivery tableted composition including a complex between poly(maleic diacid-alkyl vinyl ether) and polyvinylpyrrolidone  
A pH-dependent, controlled-release, drug delivery composition is described herein which includes: (a) a complex between poly(maleic diacid-alkyl vinyl ether) and polyvinylpyrrolidone, or their...
6126970 Cisapride sustained release  
6124037 Articles coated with in vivo polymerizable ophthalmic compositions  
Coatings for surgical instruments which comprise substituted fluoroalkyl or perfluoroalkyl monomers having anionic, cationic, and/or nonionic surface active functionality in the unsaturated...
6120781 Cosmetic or dermopharmaceutical composition in the form of a soft paste and process for preparing the said composition  
The present invention relates to a cosmetic or dermopharmaceutical composition in the form of a soft paste, which can be used for making up or treating the skin or lips, comprising, in a fatty...
6120803 Prolonged release active agent dosage form adapted for gastric retention  
The present invention is directed to an active agent dosage form which is adapted for retention in the stomach and useful for the prolonged delivery of an active agent formulation to a fluid...
6120789 Non-polymeric sustained release delivery system  
The invention relates to a method and composition for forming an implant in-situ within a body using non-polymeric materials, and the use of such implants as medical devices and drug delivery...
6117444 Polyethylene glycol/microfibrillar collagen composite serves as a resorbable hemostatic agent  
A resorbable hemostatic agent comprising a delivery component, that aids in the delivery to the wound site, and a microfibrillar hemostatic component that controls bleeding in solid tissue and does...
6117451 Direct compression metformin hydrochloride tablets  
Metformin Hydrochloride (herein referred to as metformin HCl) that may be 98.5%-100% pure is a high dose drug capable of being directly compressed with specific excipients into tablets having...
6110497 Pharmaceutical formulations  
Tablet formulations having a structure comprising compacted granulates of a mixture of a medicament and an intra-granular disintegrant, the granulates being compacted together into a tablet with an...
6106863 Sustained-release metal valproate tablets  
The present invention provides a sustained-release metal valproate tablet which is comparatively compact and is not influenced by a meal, the sustained-release metal valproate comprising a core...
6107344 Aqueous germicidal film forming composition for applying to teats of dairy cows  
Aqueous film forming compositions are disclosed that are to be applied to the teats of dairy animals to form a protective film on the teats. The protective film may be applied as a dip or spray....
6103271 Microencapsulation and electrostatic processing method  
Methods are provided for forming spherical multilamellar microcapsules having alternating hydrophilic and hydrophobic liquid layers, surrounded by flexible, semi-permeable hydrophobic or...
6103269 Solid bodies containing active substances and a structure consisting of hydrophilic macromolecules, plus a method of producing such bodies  
The invention relates to accurately meterable shaped articles, for example granules or pellets, containing hydrophilic macromolecules, active compounds and optionally further pharmaceutically...
6103264 Process for preparing a controlled release composition  
A process for preparing a controlled release composition with a controlled release matrix and containing a pharmaceutically active ingredient, which comprises granulating the active ingredient with...
6083531 Fast disintegrating oral dosage form  
6080793 Cosmetically/pharmaceutically/hygienically-active supple doughs comprising heat-sensitive compounds  
Cosmetic/pharmaceutical/hygienic compositions (e.g., lipcolors) are formulated as homogeneous and stable, supple dough extrudates, said supple dough extrudates having at least one...
6080426 Process for encapsulation of caplets in a capsule and solid dosage forms obtainable by such process  
A process for encapsulation of caplets in a capsule comprises the following steps: a. providing empty capsule parts; b. filling at least one of said capsule parts with one or more caplets; c....
6071536 Gelatin capsule having adjusted water activity  
6066334 Use of redispersible polymer powders or polymer granules as binders for producing solid pharmaceutical presentations  
Redispersible polymer powders or polymer granules consisting of a) 10-95% by weight of polyvinyl acetate, b) 5-90% by weight of an N-vinylpyrrolidone-containing polymer, c) 0-20% by weight...
6063406 Skin care compositions  
The present invention includes a process and composition for treating skin disorders. The composition of the present invention comprises 94.0 to 99.2 percent by weight of cation-free water, 0.1 to...
6060547 Film forming foundation  
The invention is a water-in-oil emulsion film forming foundation having a synergistic combination of about 0.5% to about 10% by weight of a water soluble or water dispersible film forming polymer,...
6054451 Analgesic composition and method for alleviating pain  
The analgesic effectiveness of an analgesic selected from the group consisting of (R)-5-(2-azetidinylmethoxy)-2-chloropyridine, (S)-5-(2-azetidinylmethoxy)-2-chloropyridine and pharmaceutically...
6051255 Polymer coated tablet comprising amoxycillin and clavulanate  
The present invention is to a tablet formulation, being a medicament for oral administration for the treatment of bacterial infections, the tablet comprising a compacted mixture of 750-950 mg of...
6046243 Compositions for sustained release of a gas  
A composite for retarding microbiological contamination containing a hydrophobic material containing an acid releasing agent, and a hydrophilic material containing anions that are capable of...
6037328 Method and composition for rewetting and preventing deposits on contact lens  
The present invention is directed to an ophthalmic solution for the treatment of contact lenses while worn in the eye. In particular, the composition contains ethoxylated glucose derivative,...
6037387 Blood-compatible material of a supramolecular structure  
A platelet metabolism suppressing blood compatible material has a supramolecular structure containing a plurality of cyclic compounds and a hydrophilic straight-chain polymer threading into...
6036946 Methods for protecting skin from damaging effects of ultraviolet light  
A topical antioxidant composition for the protection of skin from damage caused by ultraviolet radiation. The composition includes a first component (such as beta glucan) that increases cellular...
6034175 Salts of peptides with carboxy-terminated polyesters  
This invention relates to novel salts composed of a cation derived from a peptide containing at least one basic group and an anion derived from a carboxy-terminated polyester, processes for the...
6030644 Sustained-release granular preparations and production process thereof  
This invention relates to sustained-release granular preparations obtained by wet-granulating an aqueous suspension, which comprises a medicinal ingredient, a fine particulate polymer having an...
6027748 Pharmaceutical tablet, completely coated, for controlled release of active principles that present problems of bio-availability linked to gastro-intestinal absorption  
Described herein is a particular type of pharmaceutical tablet, for oral use, which is formed by one or more layers, and is specifically designed for controlled release of active principles that...
6027745 Process for producing controlled drug-release contact lens, and controlled drug-release contact lens thereby produced  
A process for producing a controlled drug-release contact lens, containing a first member which forms a front fact of the lens and a second member which forms a rear face of the lens, the first and...
6024980 Multiphase soft gelatin dosage form  
The present invention relates to a dosage form containing a common enclosure of polymeric material. The enclosure contains multiple phases of semi-solid fill materials containing active ingredients.
6015577 Pharmaceutical compositions containing dipyridamole or mopidamol and acetylsalicylic acid or the physiologically acceptable salts thereof, processes for preparing them and their use in treating clot formation  
The specification describes a pharmaceutical combination consisting of dipyridamole or mopidamol and acetylsalicylic acid or the physiologically acceptable salts thereof, processes for preparing...
6013283 Alkyl or olefinic endcapped polyalkylene oxide solubilizer  
A method for rendering water-insoluble materials water-soluble is provided. The method is useful for solubilizing substantially water-insoluble bioactive materials such as drugs. This is...
6010719 Freeze-dried disintegrating tablets  
Freeze-dried disintegrating tablets, said tablets containing at least a therapeutic agent, a matrix forming agent and a binding agent, in which the tablets contain more than 20% by weight of a...
6007845 Nanoparticles and microparticles of non-linear hydrophilic-hydrophobic multiblock copolymers  
Particles are provided that are not rapidly cleared from the blood stream by the macrophages of the reticuloendothelial system, and that can be modified to achieve variable release rates or to...
6001386 Implantable controlled release device to deliver drugs directly to an internal portion of the body  
A simple and implantable sustained release drug delivery device with an inner core containing an effective amount of a low solubility agent covered by a non-bioerodible polymer coating layer that...
5980927 Method and apparatus for administering analgesics, and method for making same device  
A device and method is disclosed for continuously administering an analgesic to the neuraxis of an organism. The device comprises a polymeric matrix body loaded with the analgesic. The body is...
5976521 Anti-acne cosmetic compositions  
An anti-acne cosmetic composition in the form of a multiple phase water-in-oil emulsion and process for preparing thereof, wherein the composition comprises two or more aqueous phases and a...
5977183 Solid antimicrobial compositions  
Substantially solid (or nonflowable) antimicrobial compositions have advantages over corresponding liquids and powders. Such a composition may be contained within a plastic bottle with a label...
5972381 Solid solution of an antifungal agent with enhanced bioavailability  
A pharmaceutical composition in the form of a substantially amorphous solid solution comprising an antifungal compound of the formula I: ##STR1## wherein: X is F; and R 1 is ##STR2## or an ester...