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7182956 |
Stable topical drug delivery compositions
A stable composition of a drug comprising a carrier having a phosphatidylcholine component which entraps the drug is applied to the skin for transdermal delivery of the drug.
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7176209 |
Fungicidal formulation
Adjuvants selectes from mon/ionic water/soluble mixed polyalkoxy-lated aliphatic alcohol surfactants, non ionic water soluble ethoxylated aliphatic alcohol surfactants, amine ethoxylates, and...
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7172755 |
Methods for making functionalized polymers
Polymers containing amino acid and/or polypeptide moieties in their backbones or pendant to their backbones are made by metathesis. A method of making an amino acid or polypeptide containing...
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7169819 |
Pharmaceutical compositions of fenretinide having increased bioavailability and methods of using the same
A pharmaceutical composition for parenteral delivery, comprising a retinide such as fenretinide in combination with a solvent capable of dispersing or solubilizing the retinide. The solvent...
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7163694 |
Bioerodible poly(ortho esters) from dioxane-based di(ketene acetals), and block copolymers containing them
Bioerodible poly(ortho esters) useful as orthopedic implants or vehicles for the sustained delivery of pharmaceutical, cosmetic and agricultural agents from dioxane-based di(ketene acetals). Block...
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7153520 |
Composition for sustained delivery of hydrophobic drugs and process for the preparation thereof
A composition for the sustained delivery of a drug comprising an amphiphilic diblock copolymer; a poorly water-soluble drug; a biodegradable polymer; and liquid poly(ethylene glycol) or functional...
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7153526 |
Treatment of gastrointestinal infections
A method for combating bacterial infections affecting the gastrointestinal system of humans and animals is provided. The method is achieved by diagnosing a bacterial infection affecting the...
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7147845 |
Antimicrobial silver ion complex resinates
The present invention relates to novel antimicrobial silver ion complex resinates. More particularly, the present invention contemplates silver ion complex resinate compositions comprising a...
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7144922 |
Method and compound for the prophylaxis or treatment of an immunodeficiency condition, such as AIDS
A method and compound for the prophylaxis or treatment of an immunodeficiency condition, such as acquired immunodeficiency syndrome (AIDS) includes a glycol derivative. More specifically, the...
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7138121 |
Biosensors utilizing dendrimer-immobilized ligands and there use thereof
The present invention is directed to methods and compositions useful as biosensors that specifically interact with various pathogens and other target analytes. The biosensor itself, comprises...
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7132448 |
High concentration topical insecticide containing insect growth regulator
A topical insecticide is provided which can be safe to use and avoids many common deleterious side effects of conventional topical insecticides. The insecticide contains an insecticide and an...
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7129276 |
Composition comprising at least one liquid fatty phase structured by at least one semi-crystalline polymer
A composition comprising, in a physiologically acceptable medium, at least one liquid fatty phase structured by at least one semi-crystalline polymer having an organic structure, wherein said...
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7125562 |
Rapidly disintegrating methylcellulose tablets
The present invention relates to a rapidly disintegrating tablet for oral administration. The tablet has a first phase and a second phase blended with the first phase. The first phase has a...
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7125546 |
Polymeric micelle containing cisplatin enclosed therein and use thereof
Provided is a complex comprising cisplatin encapsulated therein in a form in which a chlorine ion thereof is ligand-exchanged with a carboxyl anion of a block copolymer comprising poly(ethylene...
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7119124 |
Pharmaceutical compositions containing plasma protein
The invention is related to water-soluble products and pharmaceutical formulations in solid or liquid form mainly for parenteral use. They consist of or comprise a therapeutically active substance...
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7118761 |
Method for producing a silver-containing wound care device
Wound care devices having a topically applied silver-based antimicrobial finish are provided. The finish comprises at least one silver ion-containing compound and at least one binder compound. The...
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7115586 |
Non-inclusion cyclodextrin complexes
The invention provides a number of methods for enhancing the aqueous solubility of an active ingredient which is insoluble or sparingly soluble in water. In one preferred embodiment, solubilization...
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7115641 |
Antimicrobial oxazolidine/iodopropynyl-butyl carbamate composition containing less than 0.1wt% free formaldehyde
This invention relates to a broad spectrum antimicrobial composition, effective against gram negative and gram positive bacteria and fungi, which comprises a synergistic composition comprising...
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7112417 |
Foam composite for the repair or regeneration of tissue
The present patent describes a biocompatible composite made of a first fibrous layer attached to a three-dimensional inter-connected open cell porous foams that have a gradient in composition...
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7109166 |
Sustained release formulation of a peptide
This invention is directed to a sustained release composition comprised of Compound (A) having the formula
or a pharmaceutically acceptable salt thereof, and a copolymer comprised of...
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7109255 |
Bioresorbable hydrogel compositions for implantable prostheses
Crosslinked compositions formed from water-insoluble copolymers are disclosed. These compositions are copolymers having a bioresorbable region, a hydrophilic region and at least two cross-linkable...
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7105180 |
Stable galenic preparations comprising a benzimidazole and method for the production thereof
The invention relates to a novel benzimidazole formulation and to a process for its production. The benzimidazole formulation comprises a layer comprising the benzimidazole compound together with...
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7101840 |
Polymeric drug formulations
A method of forming a polymeric drug formulation in which a water-soluble drug is blended with a water-insoluble tissue-compatible polymer that is miscible in the solid phase with the drug, and...
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7101928 |
Polymeric thickeners for oil-containing compositions
Novel thickeners for oil-containing compositions are crystalline polymers, preferably side chain crystalline polymers, which (a) have a crystalline melting point, T p , and an onset of melting...
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7101568 |
Methods and compositions for treating solid tumors
A biodegradable polymer composition comprising:
(a) a poly(phosphoester) biodegradable polymer and (b) at least one antineoplastic agent in an amount effective to inhibit the growth of a...
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7101564 |
Plastically deformable implant
The invention relates to a plastically deformable implant for inserting into bodily orifices of the human or animal body. Implants of this type are used, for example, in ophthalmology, in...
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7097856 |
Dendrimeric support or carrier macromolecule
The present invention provides a family of dendrimers that are useful as supports, vectors, carriers or delivery vehicles for a variety of compounds in biomedical and technological applications. In...
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7094810 |
pH-sensitive block copolymers for pharmaceutical compositions
The present invention relates to a pharmaceutical composition of a biologically active agent and a block copolymer composed of a poly(ethylene oxide) forming hydrophilic segment and a poly(butyl...
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7087263 |
Rare limiting barriers for implantable medical devices
A coating for a medical device, particularly for a drug eluting stent, is described. The coating comprises a polymer having a weight-average molecular weight between about 200,000 and about 250,000...
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7084132 |
Artemisinins with improved stability and bioavailability for therapeutic drug development and application
A stable form of artemisinin wherein an artelinic acid or artesunic acid is complexed with cyclodextrin analogs, preferably, β-cyclodextrin. The complexed cyclodextrin artemisinin formulation...
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7081246 |
Stable hydroalcoholic compositions
A hydroalcoholic lotion is disclosed which comprises (a) a lower alcohol and water in a weight ratio of about 35:65 to 100:0, and (b) between at least 0.5% and 8% by weight thickener system...
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7078060 |
Solutions and aerosols of metal-containing compounds
Solutions and aerosols of metal-containing compounds are disclosed. Methods of preparing and using the solutions and aerosols, particularly in the treatment of a subject having a condition, are...
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7074830 |
System for trapping flying insects with attractant lures
The present application discloses a system for trapping flying insects, utilizing carbon dioxide in conjunction with one or more biochemical lures, visual lures or both. Preferably, a biochemical...
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7074424 |
Polyalkylene glycol viscosity-enhancing polymeric formulations
Hyaluronic acid and polyalkylene glycol (PAG) based materials have been found to exhibit a synergistic interaction, in which the viscosity of the mixture is more than twice as high as the viscosity...
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7074412 |
Pharmaceutical composition
The present invention relates to pharmaceutical compositions containing a synergistic amount of at least one bone morphogenetic protein (BMP) and a synergistic amount of at least one pyrrolidone...
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7071212 |
N-(4-carbamimidoyl-phenyl)-glycine derivatives
The invention is concerned with novel N-(4-carbamimidoyl-phenyl)-glycine derivatives of the formula:
wherein R 1 , E, X 1 to X 4 and G 1 and G 2 are as defined in the description and the...
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7070809 |
Hydrogel biomedical articles
Hydrogel biomedical articles formed from macromers having a polymeric backbone comprising 1,2-diol and/or 1,3-diol units, such as polyvinyl alcohol, and pendant chains bearing crosslinkable groups...
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7070797 |
Method of treating hematologic tumors and cancers
Multiple myeloma and other hematologic tumors and/or malignancies can be treated by administration of a G1 and/or S phase drug, which is preferably β-lapachone, or a derivative or analog thereof,...
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7063980 |
Pretreatment kit for saliva and pretreatment method for saliva
A pretreatment kit and a pretreatment kit for saliva in identification and quantitative determination of mutans streptococci by immunochromatography utilizing an antigen-antibody reaction, which...
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7060734 |
Pharmaceutical coating composition and method of use
A composition is disclosed comprising a polymer and a surfactant in a solvent exhibiting a common solubility for the polymer and the surfactant. The composition provides a dosage form for...
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7056533 |
Medicament incorporation matrix
A coating composition, in both its uncrosslinked and crosslinked forms, for use in delivering a medicament from the surface of a medical device positioned in vivo. Once crosslinked, the coating...
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7053125 |
Controlled dispersion of colloidal suspension by comb polymers
Comb polymers are used as dispersants to increase the stability of colloidal suspensions containing multivalent or high concentrations of monovalent ions. Stabilized colloidal suspensions and...
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7045542 |
Low-temperature-stable preservatives
A liquid, cold-temperature-stabilized preservative is based on carbendazim or a salt thereof, which includes, as low-temperature stabilizer, at least one aromatic alcohol and/or at least one...
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7045552 |
Pharmaceutical composition for improved administration of HIV gp41-derived peptides, and its use in therapy
Provided is a pharmaceutical composition comprising a solution comprised of synthetic peptide in a final concentration of not less than 70 mg/ml in admixture with a polyol; wherein the synthetic...
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7033603 |
Drug releasing biodegradable fiber for delivery of therapeutics
The present invention relates to fiber compositions comprising gels or hydrogels. The invention further relates to the composition of a gel or hydrogel loaded biodegradable fiber and methods of...
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7033604 |
Composition for topical administration
The present invention provides a composition for topical administration comprising an interleukin 2 inhibitor and an antimicrobial agent as active ingredients thereof, wherein said interleukin 2...
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7034061 |
Non-thrombogenic and anti-thrombogenic polymers
Polymers having non-thrombogenic properties can be prepared by copolymerizing monomers of at least three classes selected from (a) monomers having sulphate groups, (b) monomers having sulphonate...
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7029688 |
Methods and compositions to prevent formation of adhesions in biological tissues
The invention discloses materials that adsorb readily to the surfaces of body tissues in situ and provide a steric barrier between such tissues, so that tissue adhesions, which typically form...
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7022740 |
Lubricious ophthalmic solutions
There are provided lubricious ophthalmic solutions having a pH of between about 7.0 and about 8.0, consisting essentially of an aqueous solution of from about 0.5–4% by weight of a monographed...
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7022791 |
Cosmetic, pharmaceutical and dermatological products containing an electrolyte
The invention relates to cosmetic, dermatological, and pharmaceutical products containing an electrolyte. The products are obtained by free-radical copolymerization of
A)...
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