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6224907 |
Anti-asthma therapy
A dosage form is disclosed for administering a leukatriene-receptor antagonist to a patient over time.
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6221393 |
Pharmaceutical compositions in the form of sustained-release tablets based on high molecular weight polysaccharide granules
The present invention relates to a delayed-release pharmaceutical composition which is in the form of tablets prepared by direct tableting and consisting of at least one active principle and a...
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6218438 |
Copolymer compositions for treating viral infections
Compositions for delivery having a biological agent or derivative thereof, and a poly(oxyethylene)-poly(oxypropylene) block copolymer. The compositions are useful in immunodeficiency infection...
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6217903 |
Sustained release polymer blend for pharmaceutical applications
A pharmaceutical composition has a blend of at least first and second components and a medicament in a sufficient amount to be therapeutic where the first component is ethylcellulose (EC) and the...
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6217914 |
Ascorbic acid composition and method for treatment of aging or damaged skin
An ascorbic acid-based composition and related method for the treatment of aging or photo-damaged skin is disclosed. The composition includes water and ascorbic acid, at least a portion of which...
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6214366 |
Clearance and inhibition of conformationally altered proteins
The present invention provides a method of arresting, preventing and/or reversing the impairment of central and peripheral nervous system function comprising reducing insoluble protein deposit...
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6214381 |
Methazolamide composition and method of use
A pharmaceutical composition useful for treating ocular conditions, such as glaucoma. In particular, the pharmaceutical composition is a sustained release oral dosage composition for relieving...
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6214771 |
Aqueous spray compositions
An aqueous spray composition comprising about 0.0001 to 1 wt/wt % of a water-soluble poly(ethylene oxide) having a molecular weight greater than about 5×10 5 Daltons and at least about 0.05 wt/wt...
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6214331 |
Process for the preparation of aqueous dispersions of particles of water-soluble polymers and the particles obtained
The invention is a process for the preparation of crosslinked water-swellable polymer particles. First, an aqueous polymer solution containing a water-soluble polymer having at least one functional...
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6214370 |
Method and device for administering analgesics
A device and method is disclosed for continuously administering an analgesic to the neuraxis of an organism. The device comprises a polymeric matrix body loaded with the analgesic. The body is...
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6210709 |
Flexible gelatin free encapsulation material useful for pharmaceuticals, paint balls and other formulations
A flexible capsule formed from a modified starch free of animal based gelatin. The invention provides a novel capsule defining a closed interior chamber, the capsule being formulated from a...
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6210699 |
Oral transmucosal delivery of drugs or any other ingredients via the inner buccal cavity
A device and method for the oral transmucosal delivery of active substances to the oral cavity utilizing an unplasticized polyvinyl pyrrolidone polymer (PVP) as the primary mucoadhesive. The device...
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6210698 |
Suppository composition
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6211250 |
Percutaneous delivery system
The invention relates to a substantially homogenous liquid composition capable of percutaneous delivery of one or more physiologically active agents, the composition including a rate modulating...
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6211249 |
Polyester polyether block copolymers
The present invention relates to novel bioabsorbable polymeric compositions based upon AB polyester polyether or related diblocks and triblocks. Compositions according to the present invention may...
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6207180 |
Intravesical drug delivery
Bioerodible, sustained release preparations are provided for placement into the bladder through the urethra which provide sustained release of drugs. Configurations are provided which are...
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6207718 |
Pharmaceutical compositions containing hedgehog protein
A composition of a hedgehog protein which includes as an additive cyclodextrin, a non-ionic detergent, an anionic saccharide and/or ionic salt containing zinc ions, magnesium ions, calcium ions...
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6207717 |
Entrapment of vitamins with an elastomeric silicone polyether
Oil-soluble vitamins such as vitamin A and vitamin E can be entrapped in the oil phase of an elastomeric silicone polyether. The vitamin entrapped oil phase can then be emulsified and stabilized...
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6204296 |
Patient oxygenation using stabilized fluorocarbon emulsions
Storage stable fluorocarbon emulsions having a continuous aqueous phase and a discontinuous fluorocarbon phase, in which the fluorocarbon phase comprises a major amount of a first fluorocarbon or...
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6200593 |
Contraceptive method employing buccal delivery of steroidal active agents
A buccal dosage unit is provided for administering a combination of steroidal active agents to a female individual. The novel buccal drug delivery systems may be used in female hormone replacement...
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6201017 |
Ectoparasite controlling agent for animals
An ectoparasite-controlling agent for animals comprising 0.1 to 20% by weight of the neonocotinoid compounds defined in the specification and 10 to 95% by weight of a glycol or glycol monoalkyl...
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6197349 |
Particles with modified physicochemical properties, their preparation and uses
Particles comprising (a) a supercooled melt of a poorly water-soluble substance and (b) a stabilizing agent, which have a mean particle size of between 30 and 500 nm, and disperse compositions...
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6197316 |
Nail polish kits
The present invention relates to kits and films formed from the kits which are useful as cosmetic or therapeutic agents, as well as methods of their use. The films and kits herein are particularly...
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6197334 |
Lozenge and method of making
A device for delivering a liquid, semiliquid or solid beneficial agent into the mouth of a human or animal is disclosed. The device has a size and shape adapting it to be comfortably retained in...
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6194000 |
Analgesic immediate and controlled release pharmaceutical composition
Disclosed is a method for the therapeutic treatment of pain related to wind up in a human or animal. The method of the invention is practiced by administering to the subject an effective amount of...
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6194001 |
Tablet dosage form of clavulanic acid and amoxycillin comprising a trehalose excipient
Provided are tablet formulations in one embodiment comprising clavulanic acid or salt thereof, amoxycillin, and trehalose. The trehalose is, for example, amorphous anhydrous trehalose. The...
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6193985 |
Tocopherol compositions for delivery of biologically active agents
The present invention provides the use of a tocopherol or a derivative thereof as a solvent and/or emulsifier for substantially insoluble and sparingly soluble biologically active agents,...
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6191071 |
Plant-treatment agents
The invention concerns novel plant-treatment agents comprising: at least one thermoplastically processable biodegradable polyester amide, optionally in a mixture with one or a plurality of further...
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6191143 |
Topical administration of antimicrobial agents for the treatment of systemic bacterial diseases
The present invention provides a method of topically administering antimicrobial agents such as premafloxacin, premafloxacin-like compound, premafloxacin ester, ciprofloxacin, enrofloxacin,...
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6187330 |
Controlled release delivery of peptide or protein
Compositions and devices for the controlled release delivery of a peptide or protein drug are produced by dispersing a glassy matrix phase comprising the peptide or protein drug and a...
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6184257 |
Composition of ferric chloride and a dialkyl diallyl ammonium polymer and process of preparing the same
The present invention provides a novel formulation in a composition comprising FeCl 3 and a dialkyl diallyl ammonium polymer where the FeCl 3 has been diluted with water prior to being mixed with...
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6180562 |
Compositions for protecting plants from frost and/or freeze and methods of application thereof
Compositions and methods of applying the compositions to plants are disclosed. The compositions include a polymer component that releases heat over a range of dropping ambient temperatures...
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6180133 |
Antioxidant composition for topical/transdermal prevention and treatment of wrinkles
An anti-wrinkle skin treating composition comprises a pressure sensitive matrix patch having dissolved in the adhesive a mixture of antioxidants in the form of a Vitamins C ester and Vitamin E....
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6180138 |
Process for preparing solid formulations of lipid-regulating agents with enhanced dissolution and absorption
A process for the preparation of solid formulations of a lipid-regulating agent having enhanced dissolution and absorption characteristics, in which a micronized mixture of the said...
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6180687 |
In vivo polymerizable ophthalmic compositions and methods of using
In vivo polymerizable intraocular lens compositions which comprise substituted fluoroalkyl or perfluoroalkyl monomers having anionic, cationic, and/or nonionic surface active functionality in the...
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6177094 |
Bioabsorbable blends and coating composition containing same
A bioabsorbable blend is provided which comprises the reaction product of 1) a bioabsorbable copolymer obtained by polymerizing a major amount of epsilon-caprolactone and a minor amount of at least...
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6177102 |
Once daily analgesic tablet
An analgesic controlled release dosage form containing: (a) 40-80 weight percent of an analgesic; (b) 10-30 weight percent of a pharmaceutically acceptable filler; and (c) 10-30 weight percent of a...
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6168805 |
Aqueous process for manufacturing paroxetine solid dispersions
A process for preparing solid, amorphous paroxetine comprising: (A) mixing paroxetine free base or a pharmaceutically acceptable paroxetine salt with water and pharmaceutically acceptable polymer;...
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6168808 |
Synergistic composition of peracetic acid and amine oxide
Composition in the form of an aqueous solution, useful for disinfecting hard surfaces comprises: a) from 0.0005% to 20% by weight of peracetic acid, b) from 0.001% to 45% by weight of acetic...
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6166092 |
Fluorocarbon compositions for pulmonary therapy
Biocompatible fluorocarbon compositions are provided which may be used for the delivery of bioactive agents to the pulmonary air passages of a patient. Preferred compositions comprise a...
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6165456 |
Shaving compositions
An improved self-foaming shaving gel is provided which includes water, a water-soluble soap component, and a self-foaming agent, plus a hydrogenated polyisobutene in combination with a...
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6165482 |
Gastrointestinal drug composition
A composition for treating the gastrointestinal tract comprising a porous insoluble absorbent in which the pores of the insoluble absorbent are clogged by a coating material which causes the...
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6159459 |
Oral lubricating composition
An oral lubricant having particular usefulness for alleviating the symptoms of xerostomia based on a beta-glucan polymer in an orally acceptable carrier or vehicle.
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6160025 |
Liquid embolic agents
This relates to a composition of matter comprising partially hydrolyzed polyvinyl acetate solutions suitable for use as embolic agent precursors. In addition, a procedure for introducing the...
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6156803 |
Aqueous, flowable suspension concentrate of an agriculturally active chemical, and sprayable use formulation thereof
What is described is an aqueous, flowable suspension concentrate of an agriculturally active chemical having excellent dilution and storage stability, and sprayable aqueous use formulation thereof,...
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6156348 |
Methods and compositions for enhancing the bioadhesive properties of polymers using organic excipients
Methods and compositions are provided for enhancing the bioadhesive properties of polymers used in drug delivery systems. The bioadhesive properties of a polymer are enhanced by incorporating an...
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6156334 |
Wound coverings for removal of interfering factors from wound fluid
The invention relates to novel wound coverings with which interfering factors of the wound healing process can be removed from the wound fluid of chronic wounds in a controlled manner and the...
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6153193 |
Compositions for targeting biological agents
Improved pharmaceutical compositions useful in targeting biological agents to particular tissue and compositions useful for administering biological agents to the brain.
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6153644 |
Stabilized injectable pharmaceutical compositions containing taxoid anti-neoplastic agents
A stabilized, injectable pharmaceutical composition for human administration comprises (a) an antineoplastic compound,(b) a solubilizing/dispersing agent, and (c) a stabilizing amount of an...
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6149922 |
Vaccine adjuvant and vaccine
The present invention includes novel polyoxyethylene/polyoxypropylene block copolymers as well as methods for making the block copolymers. The block copolymers are high molecular weight molecules...
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