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7649023 Biodegradable block copolymeric compositions for drug delivery  
An improved drug delivery composition and method of use is disclosed. The composition comprises one or more biodegradable block copolymer drug carriers; and a reconstitution enhancing and enabling...
7649022 Bioabsorbable elastomeric polymer networks, cross-linkers and methods of use  
The invention provides elastomeric polymer networks and semi-interpenetrating networks in which a linear PEA, PEUR or PEU polymer is crosslinked by ester or alpha-amino-acid containing...
7645813 Pressure-sensitive adhesive for the skin and tapes or sheets for the skin made by using the same  
The invention provides a pressure-sensitive adhesive for the skin excellent in pressure-sensitive adhesiveness to the human skin and repeelability therefrom, which does not cause the horny layer to...
7645816 Water-soluble compositions of bioactive lipophilic compounds  
Water-soluble compositions comprising a lipophilic compound and a solubilizing agent of the general formula: {X—OOC—[(CH2)n—COO]m}p—Y (I) wherein: X is a residue of a hydrophobic moiety,Y is a re...
7638558 Polymeric micelles for drug delivery  
The present invention relates to the field of polymer chemistry and more particularly to multiblock copolymers and micelles comprising the same.
7632688 Particle having magnetic material incorporated therein, process for producing the same, particle for immunoassay and method of immunoassay  
It is an object of the present invention to provide magnetic substance-encapsulated particles which have uniform magnetism, high dispersion stability and a narrow particle size distribution, a...
7629388 Synthesis and characterization of biodegradable cationic poly(propylene fumarate-co-ethylene glycol) copolymer hydrogels modified with agmatine for enhanced cell adhesion  
A cross-linkable monomer comprises a fumaric acid functional group having a first end and a second end, a first spacer group affixed to said first end and comprising at least repeating unit, a...
7625898 Posaconazole polymer conjugates and methods of treatment using posaconazole and polymer conjugates thereof  
Improved posaconazole-based compositions and methods of treating and preventing fungal infections, cancer or metastatic diseases are disclosed. In preferred aspects, the conjugates are...
7618944 Encapsulated amyloid-beta peptides  
The present invention relates to the field of polymer chemistry and more particularly to encapsulated peptides and uses thereof.
7619009 Systems and methods for controlling and forming polymer gels  
In preferred embodiments, the present invention provides methods of controllably making a vinyl polymer hydrogel having desired physical properties without chemical cross links or radiation. The...
7615593 Bifunctional-modified hydrogels  
Disclosed are hydrogels wherein a polymer matrix is modified to contain a bifunctional poly(alkylene glycol) molecule covalently bonded to the polymer matrix. The hydrogels can be cross-linked...
7612115 Aqueous pharmaceutical compositions  
The present invention has an object to provide an antibacterial aqueous pharmaceutical composition and an aqueous pharmaceutical composition which have a sufficiently low gelation temperature even...
7597897 Medicinal compositions and method for the preparation thereof  
Methods for the manufacture of medicinal compositions are described. A method for the manufacture of a medicinal composition according to the invention comprises: (a) Providing a biocompatible...
7592341 Peptide-enhanced corneal drug delivery  
Improved methods and preparations are provided for ocular administration of therapeutic drugs. The preparations include respective quantities of a drug and a peptide which enhances transport of the...
7569643 Reverse thermal gellation polymer of chain-extended optional polyester-terminated PEO-PPO-PEO  
The present invention relates to novel polymeric compositions based upon An(BCB)An polyester/polyether multi-blocks. Compositions according to the present invention exhibit unexpectedly exceptional...
7566763 Stable dispersion concentrates  
The invention provides dispersion concentrates comprising at least one polymer obtainable by free-radical copolymerization of A) acryloyldimethyltauric acid and/or acryloyldimethyltaurates,B)...
7563824 Clathrate complexes formed by hyaluronic acid derivatives and use thereof as pharmaceuticals  
A clathrate formed by: a hyaluronic acid derivative (a), a hyaluronic acid derivative (b1) different from (a), and being able to form a clathrate with (a) and/or a component (b2) not containing a...
7560492 Polysulfone block copolymers as drug-eluting coating material  
A polymeric composition comprising a polysulfone polymer and an elastomeric polymer for use as a coating composition for coating an implantable device, such as a DES, and methods of making and...
7560493 Cosmetic and/or dermatological composition containing at least one oxidation-sensitive hydrophilic active principle and at least one N-vinylimidazole polymer or copolymer  
The invention relates to a composition for topical use containing, in a physiologically acceptable medium having an aqueous phase, at least one oxidation-sensitive hydrophilic active principle and...
7550444 Composition and method for preparing biocompatible surfaces  
The invention provides methods and compositions for providing biocompatible surfaces to medical articles. In particular the invention provides biocompatible coatings with heparin activity. In some...
7550512 Medical polymers and uses thereof  
The present invention provides a polyethylene glycol derivative having sugar residue-containing side chains and carboxyl group-containing side chains, and a method of preparing the same. The...
7547752 Scalp treatment  
A composition for topical application to the scalp comprises (i) an anti-dandruff agent; (ii) conjugated linoleic acid; and (iii) a cosmetically acceptable diluent or carrier.
7544348 Liquid formulations for the prevention and treatment of mucosal diseases and disorders  
Stable, viscous, mucoadhesive aqueous compositions which are useful for the prevention and treatment of ulcerative, inflammatory, and/or erosive disorders of mucous membranes, especially mucositis.
7540906 Metal salts of hydrolyzed olefin/maleic anhydride copolymers and their use as wood preservatives  
Complexes of copper and/or zinc with hydrolyzed olefin/maleic anhydride copolymers were solubilized in ammoniacal solution providing preservative solutions that fully penetrate wood. With loss of...
7534819 Compositions and methods for intracellular delivery of biotinylated cargo  
The invention provides compositions for intracellular delivery of biotinylated cargo. The compositions comprise a complex formed between (a) a fusion protein comprising a protein transduction...
7528176 Carbonyl-functionalized thiophene compounds and related device structures  
Carbonyl-functionalized oligo/polythiophene compounds, and related semiconductor components and related device structures.
7517914 Controlled degradation materials for therapeutic agent delivery  
According to an aspect of the present invention, polymeric release regions are provided, which contain one or more partially biodegradable progenitor polymers and which control the release of one...
7514095 Fabrication of drug loaded biodegradable polymer fibers  
The invention provides tissue engineering compositions and methods wherein three-dimensional matrices for growing cells are prepared for in vitro and in vivo use. The matrices comprise...
7507421 Hydroxycitric acid salt composition and method of making  
Disclosed is a hydroxycitric acid salt composition comprising calcium and potassium salts of hydroxycitric acid, preferably in a defined proportion which yields a very pure, stabilized preparation...
7501455 Pharmaceutical compositions containing plasma protein  
The invention is related to water-soluble products and pharmaceutical formulations in solid or liquid form mainly for parenteral use. They consist of or comprise a therapeutically active substance...
7491749 At least one polyamide polymer in a cosmetic composition comprising at least one solid substance having a melting point of 45 degrees C. or greater  
Cosmetic compositions comprising at least one structuring polymer chosen from polymers of following formula (I): in which n denotes a number of amide units, such that the number of ester groups...
7485617 Osteoinductive materials  
The present invention concerns improved osteoinductive materials comprising matrix materials and morphogenetic roteins, wherein depending on the subject matter the proteins may be dimeric or...
7482381 Artificial muscle hydrogel blends reversibly electroactuated near neutral pH, implantable actuating devices, and methods using the same  
A novel artificial muscle material and miniature valves and micropumps made therefrom are provided. The artificial muscle material bends reversibly when electroactuated by applying low voltage, in...
7479490 Pellet for a presurrized pipeline  
A system of equipment allowing addition of solid materials to a pressurized pipeline wherein said solid material is conveyed in such a way as to be readily dissolved by the liquid in said pipeline....
7470657 Cleansing composition containing an amphiphilic polymer  
The present patent application relates to a cleansing composition comprising in an aqueous medium at least one surfactant selected from alkylpolyglycosides, maltose esters, glycerolated fatty...
7465440 Process for preparing water-soluble or water-dispersible polyether-containing polymers and the use thereof as coating agents, binders and/or film-forming excipients in pharmaceutical dosage forms or packaging materials or as additives in cosmetic, dermatological or hygienic preparations  
A process for preparing graft copolymers of polyvinyl esters by polymerization of a) at least one vinyl ester of aliphatic C1-C24-carboxylic acids in the presence ofb) polyethers which are solid at...
7442721 Durable biocompatible controlled drug release polymeric coatings for medical devices  
Disclosed herein are biocompatible durable controlled drug releasing polymeric coatings for medical devices. The drug release rates of the polymers are controlled by adjusting monomer ratios and...
7429619 Polyacrylic film forming compositions  
Water soluble, gelatin-free dip coatings for substrates comprising an acrylic film former; a paraben plasticizer; and a secondary plasticizer such as polyvinylpyrrolidone, polyethylene glycol 300,...
7425581 Temperature sensitive polymers  
The present invention relates to compositions comprising polymers whose solubility characteristics can be changed by incubation and particularly poly (N-(2-hydroxypropyl)methacrylamide...
7423028 Injectable pharmaceutical compositions comprising sodium diclofenac and β-cyclodextrin  
Injectable pharmaceutical compositions are described comprising sodium diclofenac, a β-cyclodextrin and a polysorbate, suitable for subcutaneous and intramuscular administration.
7419687 Delivery vehicle for silver ions  
A delivery vehicle for a silver ion source such as silver nitrate and the like, suitable for use in the treatment of menorrhagia, comprises a plurality of physiologically inert beads bearing a...
7419685 Process for producing solid dosage forms  
Solid dosage forms containing at least one polymer binder, at least one active ingredient and, where appropriate, conventional additives, wherein a physiologically tolerated, water-swellable graft...
7407671 Temperature controlled solute delivery system  
A system for delivering solute to a target location within a mammalian body, the system including a medical device, a thermosensitive cellulose gel structure over the medical device, and a...
7405042 Method of extracting nucleic acid or protein using dendrimers and dendrimer-compositional substances  
The present invention relates to a method of extracting nucleic acid or protein, in which multi-layer dendrimers are formed on the surface of fine particles, amino radicals for capturing nucleic...
7402318 Medical devices having antimicrobial coatings thereon  
The present invention provides a medical device, preferably a contact lens, which comprises an antimicrobial coating including at least one layer of polyquat of formula (I) or (II). The...
7393840 Formulation based on heparin, glycosaminoglycan or heparinoid, use of the formulation and the formulation base  
The present invention relates to formulations based on at least one heparin, glycosaminoglycan or heparinoid and on a formulation base with a lipid component and a polymer component. The use of...
7388032 Sustained release compositions, process for producing the same and utilization thereof  
A sustained-release composition containing a hydroxynaphthoic acid salt of a biologically active substance and a biodegradable polymer, a method of its production, and a pharmaceutical composition...
7384984 Reactive hydrophilic oligomers  
Hydrophilic compositions are described, which are prepared from a first component oligomer containing pendent hydrophilic groups and pendent reactive functional groups capable of reaction at...
7381422 Method for producing sterile polynucleotide based medicaments  
The present invention relates to a novel method for producing formulations comprising a polynucleotide, block copolymer and cationic surfactant. The formulations produced by the current method are...
7381426 Targeted delivery of bioactive factors to the systemic skeleton  
The invention provides methods and compositions for the delivery of bioactive factors to the systemic skeleton. The methods of the invention allow targeted delivery of bioactive factors to bone...