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7399821 |
Alkylated poly(allylamine) polymers and methods of use
The invention relates to a method for removing bile salts from a patient in need thereof and compositions useful in the method. The method comprises administering to the patient a therapeutically...
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7393825 |
Microdose therapy
Methods for treating vascular conditions associated with localized imbalance in vascular tone, which are hypothesized to be largely due to elevated endothelin (ET) are provided. The methods involve...
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7189761 |
Nitric oxide donor composition and method for treatment of anal disorders
A pharmaceutical composition contains a nitric oxide donor and advantageously an optional corticosteroid and/or topical anesthetic. The composition is useful in a method for treating anal disorders...
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7157500 |
Nitrosylation of protein SH groups and amino acid residues as a therapeutic modality
Nitrosylation of proteins and amino acid groups enables selective regulation of protein function, and also endows the proteins and amino acids with additional smooth muscle relaxant and platelet...
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7148259 |
Antibacterial agents
Hydroxyamidines and related compounds are provided which are suitable as antibacterial agents.
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6903100 |
USE OF REGULARLY SCHEDULED HIGH DOSE INTRAVENOUS METHOTREXATE THERAPY, WITH INTERIM ADMINISTRATION OF IMMUNOMODULATORY AGENTS, TO TREAT MULTIPLE SCLEROSIS AND OTHER DISEASES OF THE CENTRAL NERVOUS SYSTEM
The present invention is directed to the treatment of multiple sclerosis by periodically administering a high dose of methotrexate at a level sufficiently high to cross the blood brain barrier. The...
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6844320 |
Treatment of preeclampsia, toxemia and preterm labor with combination of progestational agent and a nitric oxide synthase substrate and/or donor
Preeclampsia and preterm labor in a pregnant female mammal are treated by administering thereto a combination of a progestin and a nitric oxide synthase substrate, a nitric oxide donor or both,...
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6784254 |
Process for removing bile salts from a patient and alkylated compositions therefor
The invention relates to a method for removing bile salts from a patient in need thereof and compositions useful in the method. The method comprises administering to the patient a therapeutically...
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6664297 |
Methods for inhibition and dissolution of amyloidoses by administration of compositions comprising 2,4-dinitrophenol
The inhibition of the formation and development of amyloidoses, as well as the dissolution of amyloidoses in organisms is claimed. Methods for the diagnosis of amyloidoses using aromatic and...
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6562329 |
Method of treating high plasma cholesterol levels
A method prevents or treats diseases associated with high plasma cholesterol levels. In addition, this method reduces plasma cholesterol levels. The method comprises administering a lipase...
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6472425 |
Methods for treating female sexual dysfunctions
The present invention provides methods for treating female sexual dysfunctions by administering to a female individual a therapeutically effective amount of at least one compound that donates,...
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6472390 |
Use of therapeutic dosages for nitric oxide donors which do not significantly lower blood pressure or pulmonary artery pressure
Patients with pathologic conditions involving constriction or proliferation of smooth muscle or disease associated with cysteine containing proteins, or who are at risk for such, are administered a...
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6436996 |
Modulation of nitric oxide production
A method of treating cells that carry at least one APOE4 allele comprises increasing nitric oxide levels in the cells (e.g., by administering an exogenous source of nitric oxide to the cells) by an...
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6432413 |
Functional improvements in Fahr disease
The invention provides methods of treating diseases of the central and peripheral nervous systems that are associated with abnormal calcifications within the nervous system, such as Fahr disease....
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6342499 |
Parasitic and saprophagous mite control in beneficial insects
The present invention provides a method to control parasitic and saprophagous mites on beneficial insects such as honeybees via the application of a parasiticidally or saprophagouscidally effective...
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6294583 |
Methods of treating tardive dyskinesia and other movement disorders
The present invention describes a novel treatment for movement disorders, including tardive dyskinesia, tic disorders, Tourette's syndrome, and blepharospasm, and other focal dystonias. The...
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6287601 |
Topical nitric oxide donor compositions
Compositions and methods of the topical treatment of equine laminitis are disclosed. In particular, combinations of a fast acting nitric oxide (NO) donor, a sustained acting NO donor and an NSAID...
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6277891 |
Nitric oxide inhibits rhinovirus infection
Nitric oxide generating compounds or compounds which induce in situ synthesis of nitric oxide can be used to inhibit rhinovirus infection. Nitric oxide has the ability to inhibit both viral...
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6133320 |
Treatment of osteoporosis and metabolic bone disorders with nitric oxide substrate and/or donors
Primary and secondary osteoporosis in a female or a male mammal is treated by administering thereto a nitric oxide synthase substrate, a nitric oxide donor or both, optionally; in further...
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6075044 |
Heterocyclic derivatives as inhibitors of purine salvage phosphoribosyltransferases
The use of certain heterocyclic derivatives for treating parasitic protozoa infections in mammals, in particular bovine trichomoniasis and giardiasis, is disclosed.
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6071876 |
Method of preventing NMDA receptor complex-mediated neuronal damage
Disclosed is a method for decreasing NMDA receptor-mediated neuronal damage in a mammal by administering to the mammal a nitroso-compound that generates nitric-oxide or related redox species, in a...
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6066649 |
Drug for cardiovascular diseases
The invention relates to a drug, which contains one or more inhibitors for the cGMP-stimulated phosphodiesterase (PDE II) together with conventional substrates and/or diluents. Preferably the drug...
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6045827 |
Treatment of equine laminitis
Compositions and methods of the topical treatment of equine laminitis are disclosed. In particular, combinations of a fast acting nitric oxide (NO) donor, a sustained acting NO donor and an NSAID...
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5997874 |
Dihydrophenanthrene
The present invention relates to a class of dihydrophenanthrene which are isolated from Calanthe discolor Lindl. and derivatives thereof.
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5973011 |
Pharmaceutical preparations and medicaments for the prevention and treatment of endothelial dysfunction
The present invention describes the use of nitric-oxide-liberating or transferring compounds, stimulators of endogenous NO formation, as well as stimulators of guanylate cyclase, for prevention,...
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5965529 |
Treatment of preeclampsia and preterm labor with combination of progestational agent and a nitric oxide synthase substrate and/or donor
Preeclampsia and preterm labor in a pregnant female mammal are treated by administering thereto a combination of a progestin and a nitric oxide synthase substrate, a nitric oxide donor or both,...
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5962413 |
Treatment of uterine contractility disorders with a nitric oxide synthase substrate and/or donor, or a nitric oxide inhibitor
Dysmenorrhea, disfunctional uterine bleeding, preterm labor and postpartum labor in female mammals are treated by inhibiting uterine contractility by administering thereto a nitric oxide synthase...
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5942512 |
Method and composition for treating erectile dysfunction
Lipophilic active substance composition and its use in a new method of treating erectile dysfunction by administration thereof, optionally together with a hydrophilic vehicle and optionally an...
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5849803 |
Method of treating erectile dysfunction with nitroglycerine
Lipophilic active substance composition and its use in a new method of treating erectile dysfunction by administration of nitroglycerine together with a hydrophilic vehicle and optionally an...
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5801203 |
Nitroglycerine patch
Disclosed is a method and patch for decreasing NMDA receptor-mediated neuronal damage in a mammal by administering to the mammal a nitroso-compound that generates nitric-oxide or related redox...
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5739022 |
Copper(II) nuclease compounds, compositions, and kits
A method is provided for nonoxidatively cleaving the phosphorus-oxygen linkage of nucleic acids and certain anticholinesterases such as insecticides using a macrocyclic copper(II) complex. A...
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5693675 |
Alkylated amine polymers
The invention relates to alkylated amine polymers and a method for removing bile salts from a patient that includes administering to the patient a therapeutically effective amount of product...
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5679717 |
Method for removing bile salts from a patient with alkylated amine polymers
A method for removing bile salts from a patient that includes administering to the patient a therapeutically effective amount of product produced by a process comprising alkylating one or more...
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5504117 |
Pharmacologic preparation for the treatment of anal disorders
A medical preparation for treating anal disorders comprises an effective amount of a nitric oxide donor, preferably an organic nitrate. The preparation may be in the form of an ointment that is...
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5470848 |
Penetration enhancers for transdermal delivery of systemic agents
This invention relates to a method for administering systemically active agents through the skin or mucosal membranes of humans and animals and into the bloodstream in a transdermal device or...
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5455279 |
Regimen method of mediating neuronal damage using nitroglycerine
Disclosed is a method for decreasing NMDA receptor-mediated neuronal damage in a mammal by administering to the mammal a nitroso-compound that generates nitric-oxide or related redox species, in a...
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5214041 |
Hair revitalizing tonic composition
A hair revitalizing tonic composition comprising (i) an amine oxide and (ii) a compound having a calmodulin inhibitory activity and/or a compound having an activity as a calcium antagonist.
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5059603 |
Method and composition for treating impotence
A composition for treating impotence contains a vasodilator, a vasoconstrictor, and a penetration enhancing ingredient in a pharmaceutically acceptable carrier for topical application. The...
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5026546 |
Stabilized adjuvant suspension comprising dimethyl dioctadecyl ammonium bromide
A stabilized aqueous adjuvant suspension of dimethyl dioctadecyl ammonium bromide stabilized with at least 0.1 part by weight of a polymer of acrylic acid crosslinked with polyallyl sucrose per...
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4952401 |
Rodenticide for toxic wick
A composition and a method of using the same wherein said composition comprises a rodenticide and an additive selected from the group consisting of 1. polyoxyalkylated alkyl phenols; 2....
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4654209 |
Preparation for percutaneous administration
A preparation for percutaneous administration of nitroglycerine, said preparation comprising nitroglycerine incorporated in a cream base in an amount not less than about 0.05% by weight based on...
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4482534 |
Nitroglycerin preparations
A mixture of nitroglycerin and a water-insoluble vinylpyrrolidone polymer provides a polymeric matrix which gradually releases nitroglycerin upon application to the skin of a patient in the form of...
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4381194 |
Alkali lignin based pesticide phytotoxicity reducing composition
A method for protecting crops from injury caused by the application of herbicides and fungicides has been discovered, the method comprising applying to the crops in combination with the pesticide a...
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3342671 |
1, 4-dihalo-1, 4-dinitro-1, 3-butadiene foliage fungicides and bactericides
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3238093 |
Nematocidal 1, 1-dihaloethylenes
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3139377 |
1, 1-dihalo-butadiene-1, 3 nematocides
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3055801 |
1-substituted pyrenes as fungicides
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2924527 |
Duck feeds
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2924524 |
Swine feed supplement
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2872367 |
Insecticidal compositions containing 9,9'-bifluorylidene
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