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RE40246 |
Method for the suppression of viral growth
A method for suppressing undesired viral growth in a host which comprises administering to the host an effective amount of a compound of the formula:
wherein R 1 , R 2 , R 3 and R 4 are...
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7335659 |
Substituted 10-aryl-11H-benzo[b]fluorenes and 7-aryl-5, 6-dihydro-benzo[a]anthracenes for selective effects on estrogen receptors
This invention provides a compound, or its possible salt, having the formula,
wherein: R e and ′R e are OH, optionally independently etherified or esterified; Z is —CH 2 CH 2 — or...
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7307071 |
RAF-MEK-ERK pathway inhibitors to treat cancer
Materials and methods for treating certain cancers are described, preferably cancers that result from the up-regulation of the RAF-MEK-ERK pathway, and more preferably chronic myelogenous leukemia,...
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7220783 |
Para-terphenyl compounds
The present invention provides a selective suppressor of the IgE production comprising a compound which suppresses the IgE production in a process from a differentiation of a mature B cell into an...
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7157419 |
Growth factor binding molecules
Growth factor binding molecules having a plurality of peptide loops attached to a non-peptide organic scaffold, preferably having pseudo-six amino acid peptide loops with four amino acid...
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7109245 |
Vasoconstrictor cannabinoid analogs
Methods and compounds for reversing pathological vasodilation of blood vessels, for example vasodilation caused by activation of CB1-like receptors, by administering to a subject a therapeutically...
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7105577 |
Antimicrobial method using a hydroxydiphenyl ether compound
The present invention relates to the use of hydroxydiphenyl ether compounds as antimicrobially active substances, to certain new compounds of this type and to processes for the preparation of these...
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7101915 |
P-terphenyl compounds
The present invention provides a selective suppressor of the IgE production comprising a compound which suppresses the IgE production in a process from a differentiation of a mature B cell into an...
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7074836 |
Para-terphenyl compounds
The present invention provides a selective suppressor of the IgE production comprising a compound which suppresses the IgE production in a process from a differentiation of a mature B cell into an...
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7056862 |
Herbicide potentiators
The invention provides an agricultural chemical enhancer and an agricultural chemical composition which are safely used for crops without any phytotoxicity, have a potency enhancing action on...
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7041307 |
Biocide-polyester concentrates and biocidal compositions prepared therefrom
Concentrates of various classical biocides in a polyester carrier resin when incorporated into a substrate resin, preferably a polyolefin such as polypropylene or polyethylene, provide the...
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7030162 |
Treatment of migraine headache
The invention is directed to pharmaceutical compositions useful in the treatment of migraine. The compositions contain metoclopramide and one or more NSAIDs in unit dosage form. By selecting NSAIDs...
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7001926 |
Tubulin binding agents and corresponding prodrug constructs
A diverse set of tubulin binding agents have been discovered which are structurally characterized, in a general sense, by a semi-rigid molecular framework capable of maintaining aryl-aryl, pseudo...
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6984665 |
Methods for the inhibition of atrophy or for treatment or prevention of atrophy-related symptoms in women
This invention relates to a method for inhibition of skin atrophy, or epithelial or mucosal atrophy in women, or to a method for treatment or prevention of symptoms related to said atrophy, said...
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6949551 |
Dihalopropene compounds, processes for their preparation, compositions comprising them and their use as pesticides
Dihalopropene compounds, process for their preparation, compositions comprising them and their use as pesticides What is described are dihalopropene compounds of the formula (I)
in which R 1 ...
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6933321 |
Antiandrogenic biphenyls
Biphenyl derivatives are disclosed for use in the treatment of androgen-dependent diseases, such as prostate cancer, benign prostatic hyperplasia, precocious puberty, polycystic ovarian syndrome,...
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6855341 |
Anti-viral compositions and methods of making and using the anti-viral compositions
Disclosed are anti-viral compositions containing at least one zinc compound and at least one phenolic antioxidant (and optionally other ingredients), and a pharmaceutical carrier. Also disclosed...
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6835386 |
Collar containing a novel gel formulation to control arthropod infestation of animals
The present invention provides a device, preferably a collar or ear tag, capable of the controlled, sustained release of an effective amount of an active ingredient that can protect an animal...
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6797728 |
Use of intracellular calcium chelators to increase surfactant secretion in the lungs
Pulmonary surfactant is required in order to reduce surface tension in the lungs so that less effort is needed to reinflate the lungs after exhalation. A number of diseases and conditions exist...
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6790868 |
Non-halogenated phenoxy and/or benzyloxy substituted phenols, antimicrobial compositions containing the same, and methods of using the same
Antimicrobial compounds, compositions containing the same, and methods of using of the same for reducing the presence of microorganisms on a substrate or in a fluid environment comprising an...
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6777444 |
Method for regulation of gene expression in eukaryotic cells using nordihydroguaiaretic acid derivatives
Use of nordihydroguaiaretic derivatives to suppress CDC-2 and survivin, stimulate apoptosis, and treat tumors.
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6773702 |
Use of combretastatin A4 and its prodrugs as an immune enhancing therapy
A method of treating immune suppression in a warm-blooded animal bearing a tumor, by administering to the animal an amount of combretastatin A4 and/or a prodrug thereof effective to enhance immune...
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6767923 |
Benzhydryl derivatives
Benzhydryl derivatives of the formula I, where the index and the variables are as defined below: X is oxygen or sulfur; R 1 , R 3 are halogen, cyano, nitro, hydroxyl, mercapto, amino, alkyl,...
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6686371 |
Non-steroidal, tetracylic compounds for estrogen-related treatments
The invention provides non-steroidal estrogenic compounds with estrogenic and anti-estrogenic compounds effects for treatment of estrogen-deficiency related disorders, which compounds are having...
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6677383 |
Hydroxylation activated prodrugs
The present invention concerns enzymatic aromatic hydroxylation-activated prodrugs, particularly anti-tumor prodrugs and those which are specifically activated by the hydroxylation activity of the...
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6641800 |
Pressurized aerosol compositions comprising powdered medicament dispersed in hydrofluoroalkane
Pressurized aerosol composition for administration by inhalation comprising a liquefied hydrofluoroalkane, a powdered medicament dispersed therein, and a suspending agent comprising a polymer...
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6635663 |
Pesticidal emulsifiable concentrate
The present invention provides a low-irritant pesticidal emulsifiable concentrate comprising (a) 1 to 60% by weight of at least one pesticidal active ingredient compound selected from the group...
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6593374 |
Tubulin binding ligands and corresponding prodrug constructs
A diverse set of tubulin binding ligands have been discovered which are structurally characterized, in a general sense, by a semi-rigid molecular framework capable of maintaining aryl—aryl,...
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6583161 |
Benzenesulfonamides and benzamides as therapeutic agents
The invention provides compounds, compositions and methods relating to novel aromatic derivatives and their use as pharmacologically active agents. The compositions find particular use as...
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6582683 |
Dermal barrier composition
Disclosed is a dermal barrier composition which contains a hydrophilic polymer emulsion and a hydrophobic polymer emulsion. The dermal barrier composition is moisture activated, and remains inert...
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6534088 |
Fibrate-statin combinations with reduced fed-fasted effects
This invention discloses an orally administered pharmaceutical composition for the treatment of elevated levels of cholesterol and related conditions comprising a statin and fenofibrate in the form...
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6515007 |
Methods for managing scalp conditions
This application relates to a pharmaceutical composition for the prevention, treatment, and management of scalp conditions, such as dandruff, seborrheic dermatitis, psoriasis, folliculitis, and...
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6500416 |
Pesticide
There are described a flowable composition for controlling harmful insects and representatives of the order Acarina, comprising at least one pesticidally active compound, one or more signal...
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6498191 |
Mitochondria protecting agents for treating mitochondria associated diseases
The present invention relates generally to mitochondria protecting agents for treating diseases in which mitochondrial dysfunction leads to tissue degeneration and, more specifically, to compounds,...
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6489366 |
Combinations of cholesteryl ester transfer protein inhibitors and nicotinic acid derivatives for cardiovascular indications
The present invention provides combinations of cardiovascular therapeutic compounds for the prophylaxis or treatment of cardiovascular disease including hypercholesterolemia, atherosclerosis, or...
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6479551 |
Treatment of migraine headache
The invention is directed to pharmaceutical compositions useful in the treatment of migraine. The compositions contain metoclopramide and one or more NSAIDs in unit dosage form. By selecting NSAIDs...
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6475505 |
Biocide-polyester concentrates and biocidal compositions prepared therefrom
Concentrates of various classical biocides in a polyester carrier resin when incorporated into a substrate resin, preferably a polyolefin such as polypropylene or polyethylene, provide the...
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6461591 |
Medical aerosol formulations
A pressure-liquefied propellant mixture for aerosols, comprising a fluorinated alkane, in particular 1,1,1,2-tetrafluoroethane and/or 1,1,1,2,3,3,3-heptafluoropropane, and carbon dioxide, makes...
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6423753 |
Use of colchinol derivatives as vascular damaging agents
Colchinol derivatives of formula wherein R 1 , R 2 , R 3 and R 6 are each independently H, optionally substituted alkyl, cycloalkyl, alkenyl, alkynyl, aralkyl, alkanoyl, PO 3 H 2 ; X is...
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6384085 |
Material separated from Ecklonia cava, method for extracting and purifying the same, and use thereof as antioxidants
Disclosed are novel materials separated from Ecklonia cava , a method for extracting and purifying the same, and the use thereof for antioxidants. The method comprises extracting antioxidative...
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6369115 |
Stabilized powder formulations
A dry powder formulation for treatment of pulmonary conditions, via inhalation, includes an effective amount of formoterol or a salt or solvate thereof, in a dry powder form, an effective amount of...
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6350777 |
Description anti-mitotic agents which inhibit tubulin polymerization
Methoxy and ethoxy substituted 3-aroyl-2-arylbenzo[b]thiophenes and benzo[b]thiophene analogues are described for use in inhibiting tubulin polymerization. The compounds' use for treating tumor...
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6291524 |
Method for the suppression of viral growth
A method for suppressing undesired viral growth in a host which comprises administering to the host an effective amount of a compound of the formula: ##STR1## wherein R 1 , R 2 , R 3 and R 4 are...
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6288011 |
1,4-diaryl-2,3-difluoro-2-butene insecticidal and acaricidal agents
Pesticidal 1,4-diaryl-2,3-difluoro-2-butene compounds having the structural formula I ##STR1## and compositions and methods comprising those compounds for the control of insect and acarid pests.
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6277829 |
Process for preparing of aqueous formulation for opthalmic use
The present invention describes a process for the preparation of aqueous formulations containing azithromycin for ophthalmic use, as well any formulations obtained by this process and their topical...
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6274570 |
Pesticidal compositions
A liquid pesticidal composition, which is substantially free of water, comprising a hydrophobic pesticide or mixture of pesticides dissolved in an organic solvent and comprising as surfactants (a)...
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6258835 |
Synergistic pesticidal composition of pyrethroid and N-phenyl-pyrazole
The present invention provides an insecticidal composition comprising, as active ingredients, (a) at least one pyrethroid compound and (b) an N-aryldiazole compound such as...
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6251942 |
Compositions and methods for alleviating impaired mental function, memory loss and reducing recovery time in anaesthetized mammals
Composition and methods of alleviating impaired mental function and memory loss in mammals and reducing the recovery time from anaesthesia in age mammals, comprising treating the mammal with a...
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6245819 |
Method for the treatment of vaginal dryness and sexual dysfunction in women during or after the menopause
This invention concerns a method for the treatment of vaginal dryness or sexual dysfunction in women during or after the menopause, said method comprising administering to the woman an effective...
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6239170 |
Inhibition of hair growth
Mammalian hair growth is reduced by applying to the skin a composition including an inhibitor of 5-lipoxygenase.
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