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7449495 |
Retinoid derivatives with antiangiogenic, antitumoral and proapoptotic activities
Described and claimed are compounds of Formula (I) in which R, R′, R″, A, and D have the meanings described in the text, as useful agents in the cure of pathologies characterized by altered...
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7358236 |
Control of acute hypertension and cardiotoxicity in patients treated with vascular targeting agents
The present invention provides a method of using anti-hypertensive agents (“AHAs”) to attenuate the transient increase in blood pressure observed in patients where Vascular Targeting Agents...
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7291650 |
Cancer treatment composition and method using natural plant essential oils
Pharmaceutical compositions containing plant essential oils, natural or synthetic, or mixtures or derivatives thereof, for the prevention and treatment of soft tissue cancer in mammals.
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7109245 |
Vasoconstrictor cannabinoid analogs
Methods and compounds for reversing pathological vasodilation of blood vessels, for example vasodilation caused by activation of CB1-like receptors, by administering to a subject a therapeutically...
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7056862 |
Herbicide potentiators
The invention provides an agricultural chemical enhancer and an agricultural chemical composition which are safely used for crops without any phytotoxicity, have a potency enhancing action on...
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6933320 |
Combination comprising combretastatin and anticancer agents
An antitumor combination comprising a stilbene derivative and an anticancer compound selected from the group consisting of taxanes, alkylating agents, antimetabolites, vinca alkaloids, platinum...
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6875775 |
Triphenylalkene derivatives and their use as selective estrogen receptor modulators
The invention provides novel selective estrogen receptor modulator compounds of the general formula:
wherein R1 and R2, which are the same or different are
a) H, halogen, OCH 3 , OH; or...
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6841577 |
Pesticidal activity of plant essential oils and their constituents
A pesticide for cockroaches and larvae which is based on purified naturally occurring plant substances. Phenethyl propionate; methyl salicylate; pulegone; carvacrol; thymol; thyme oil; citronellal;...
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6835754 |
Use of aryl nitrone compounds in methods for treating neuropathic pain
3,4,5-trisubstituted aryl nitrone compounds having the formula: where R 1 -R 4 are as defined in the specification are useful as therapeutics for neuropathic pain conditions in mammals.
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6790868 |
Non-halogenated phenoxy and/or benzyloxy substituted phenols, antimicrobial compositions containing the same, and methods of using the same
Antimicrobial compounds, compositions containing the same, and methods of using of the same for reducing the presence of microorganisms on a substrate or in a fluid environment comprising an...
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6774123 |
Methods and compositions for inactivating viruses
Methods and compositions for selectively inactivating viruses in biological compositions, including contacting the composition with an organic solvent and an ethyleneimine oligomer inactivating...
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6773702 |
Use of combretastatin A4 and its prodrugs as an immune enhancing therapy
A method of treating immune suppression in a warm-blooded animal bearing a tumor, by administering to the animal an amount of combretastatin A4 and/or a prodrug thereof effective to enhance immune...
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6740338 |
Reduced form of Cenzyme Q in high bioavailability stable oral dosage form
The present invention relates to a reduced form of Coenzyme Q also known as ubiquinol in oral dosage form such as a gelatin capsule, preferably a soft gelatin capsule. Compositions according to the...
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6696484 |
Method and compositions for regulation of 5-alpha reductase activity
Pharmaceutical compositions and methods for treating androgen related disorders. The pharmaceutical compositions may include a 5α-reductase inhibitor, such as natural and synthetic flavanoids,...
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6677383 |
Hydroxylation activated prodrugs
The present invention concerns enzymatic aromatic hydroxylation-activated prodrugs, particularly anti-tumor prodrugs and those which are specifically activated by the hydroxylation activity of the...
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6653327 |
Cross-regulin composition of tumeric-derived tetrahydrocurcuminoids for skin lightening and protection against UVB rays
The present invention is directed to a mixture of tetrahydrocurcuminoids which can be used for regulating random, intracellular protein cross-linking an optimizing cell electric potential in a...
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6624197 |
Diphenylethylene compounds
Novel diphenylethylene and styrenes are provided which are administered orally to decrease blood glucose levels in rats. The glucose tolerance in insulin resistant rats is also shown, as well as...
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6576660 |
Methods and compositions for regulation of 5-α-reductase activity
Compounds that inhibit 5-alpha-reductase are provided. The compounds are used to treat prostate cancer, breast cancer, obesity, skin disorders and baldness.
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6576645 |
Triphenylalkene derivatives and their use as selective estrogen receptor modulators
The invention provides novel selective estrogen receptor modulator compounds of the general formula: wherein R1 and R2, which are the same or different are a) H, halogen, OCH 3 , OH; or where...
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6518261 |
Use of eugenol in combination with other chemopreventative agents as prophylaxis for cancers
The use of eugenol, alone and in combination with 2-methoxyestradiol (2-ME) in the context of prostate cancer prophylaxes and treatment.
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6444709 |
Heteroethylene compounds and pharmaceutical and cosmetic compositions containing same
The invention relates to novel heteroethynylenic compounds having the general formula (I): as well as to the use of these compounds in pharmaceutical compositions intended for use in human or...
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6444230 |
Synergistic composition of peracetic acid and amine oxide
Composition in the form of an aqueous solution, useful for disinfecting hard surfaces comprises: a) from 0.0005% to 20% by weight of peracetic acid, b) from 0.001% to 45% by weight of acetic acid,...
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6288011 |
1,4-diaryl-2,3-difluoro-2-butene insecticidal and acaricidal agents
Pesticidal 1,4-diaryl-2,3-difluoro-2-butene compounds having the structural formula I ##STR1## and compositions and methods comprising those compounds for the control of insect and acarid pests.
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6274635 |
Alkylated resorcinol derivatives for the treatment of immune diseases
The present invention provides a method, compounds, and compositions for treating a disease associated with immune dysfunction. In accordance with the method, a pharmacologically-acceptable...
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RE37087 |
Insecticidal triffluormethyl alkane derivatives
There are provided new alkane and alkoxyalkane derivatives of the general formula I ##STR1## in which R 1 , R 2 , R 3 , R 4 and A have the meanings given in the description, processes for their...
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6184255 |
Pharmaceutical composition comprising coenzyme Q10
The present invention has for its object to provide a medicinal composition comprising coenzyme Q 10 as an active ingredient, which composition features an enhanced absorption after oral...
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6183733 |
Compositions and methods of attracting overwintering boll weevils
Compositions and methods for attracting, killing, and/or neutering populations of boll weevils and other insects which spend the winter in areas with thick vegetation are disclosed. With respect to...
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6168808 |
Synergistic composition of peracetic acid and amine oxide
Composition in the form of an aqueous solution, useful for disinfecting hard surfaces comprises: a) from 0.0005% to 20% by weight of peracetic acid, b) from 0.001% to 45% by weight of acetic...
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6156802 |
Cholesterol-lowering composition
The present invention has its object to provide an antihypercholesterolemic or antihyperlipidemic agent, hence a therapeutic and prophylactic drug for arteriosclerosis, which is safer and more...
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6143311 |
Iodopropargyl derivatives and antimicrobial agents comprising them as an active ingredient
The present invention provides novel iodopropargyl derivatives represented by the following formula (1): ##STR1## wherein R 1 is a methoxy group or a cyano group, which have a reduced unpleasant...
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6136865 |
Method for reduction of the infectiousness of potentially infectious material
A method for reduction of the viral infectiousness of potentially infectious material, such as human or animal body fluids or fractions derived therefrom from which biologically active substances...
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6130253 |
Terpene based pesticide treatments for killing terrestrial arthropods including, amongst others, lice, lice eggs, mites and ants
Pesticides for the extermination of terrestrial arthropods are disclosed which comprise formulations of a combination of terpenes in aqueous solutions which may be used together with citral. No...
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6127417 |
Stable derivatives of ubiquinole, processes for their production and pharmaceutical use thereof
New stable derivatives of ubiquinole are described, having general formula (I), along with processes for their production and their pharmaceutical use, in particular in the treatment of...
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6074634 |
Feeding attractant and stimulant for adult control of noctuid and/or other lepidopteran species
The present invention provides an composition for attracting noctuid and/or other lepidopteran species. Liquid and solid formulations are provided, along with methods for their use, for controlling...
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5989559 |
Banana peel extract composition and method for extraction
An extract composition derived from the peel of a banana and the method for producing the extract composition. An aqueous solvent is combined with the peel of a banana. If the banana is unripe, a...
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5912273 |
Triphenylethylenes compositions
A pharmaceutical composition is provided for use in the prevention or treatment of osteoporosis comprising a therapeutically effective amount of a compound of formula (I) ##STR1## wherein R 1 and...
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5880162 |
Pesticidal fluoroolefins
A pesticidal compound of formula I: ##STR1## in which formula: either R 1 is hydrogen and R 2 represents a cyclopropyl group or R 1 and R 2 each represent an alkyl group, which alkyl groups may...
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5869506 |
Fluoropropene compound, an insecticide containing the same and an intermediate for production thereof
The present invention provides a fluoropropene compound represented by Formula I: ##STR1## wherein R 1 represents a C 1 -C 10 alkyl group or other groups, Z represents an oxygen atom or other...
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5861415 |
Bioprotectant composition, method of use and extraction process of curcuminoids
Curcuminoids have been found to have anti-oxidant, anti-inflammatory, antibacterial, antifungal, antiparasitic, anti-mutagen, anticancer and detox properties. The present invention is directed to...
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5859017 |
Method for inhibiting mast cell and basophil activation
In a method for treating or preventing allergy or allergic disorders an effective amount of a compound that inhibits intracellular generation of phosphatidic acid and diacylglycerol is...
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5750576 |
Triphenylethylenes for the prevention and treatment of osteoporosis
Compounds having formula (I) wherein R 1 and R 2 are independently H or OH, are useful in the treatment and prevention of osteoporosis. The compounds of formula (I) are devoid of significant...
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5629340 |
Angiogenesis inhibitor and novel compound
An angiogenesis inhibitor comprising, as an active agent, Compound (I) represented by the formula below: ##STR1## where R 1 is a lower alkyl group, an alkoxycarbonyl group or a carboxyl group; and...
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5571794 |
Non-invasive novel method fo cosmetic lip augmentation
A cosmetic treatment for inducing upper and lower lip augmentation in humans, wherein an active ingredient encouraging vasodilatation, preferably an ultra highly diluted homeopathic, ultra highly...
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5565191 |
Cosmetic and dermatological compositions for the protection against UV radiation containing stilbene derivatives
Stilbene derivatives of formula (I) ##STR1## wherein A, R 1 and R 2 are as defined in the following, are useful for the protection against UV radiation.
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5563134 |
Pharmaceutical compositions comprising clozapine and a radical scavenger
The invention concerns pharmaceutical compositions comprising clozapine and a radical scavenger.
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5530015 |
Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound
There is disclosed a dihalopropene compound of the formula I: ##STR1## wherein l is an integer of 1 to 5; m is an integer of 1 to 4; R 1 's and R 2 's are the same or different and are...
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5492687 |
Compositions of iodophenoxy alkylene ethers and pharmaceutically acceptable clays for visualization of the gastrointestinal tract
Disclosed are x-ray contrast compositions for oral or retrograde examination of the gastrointestinal tract comprising iodophenoxy alkylene ethers and pharmaceutically acceptable clays in a...
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5466435 |
Compositions of iodophenoxy alkylene ethers and cellulose derivatives for visualization of the gastrointestinal tract
Disclosed are contrast agents of the formula ##STR1## wherein Z is H, halo, C 1 -C 20 alkyl, cycloalkyl, lower alkoxy, alkoxycarbonyl, cyano, where the alkyl and cycloalkyl groups can be...
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5430062 |
Stilbene derivatives as anticancer agents
The present invention relates to stilbene derivatives which possess utility as anti-cancer agents. The compounds can be used to treat cancers which are susceptible to treatment therewith, and can...
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5393776 |
Tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia
This invention relates to structurally novel acyclic tocotrienol analogs, which are useful for cholesterol/lipid lowering in cases of hypercholesterolemia and hyperlipidemia, and for...
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