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7625950 |
Amino-propanol derivatives as sphingosine-1-phosphate receptor modulator
Compounds of formula (I)
wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , X, Y and n are as defined in the specification, processes for their production, their uses and pharmaceutical...
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7582803 |
Conformationally constrained 3-(4-hydroxy-phenyl)-substituted-propanoic acids useful for treating metabolic disorders
The present invention provides compounds useful, for example, for treating metabolic disorders in a subject. Such compounds have the general formula I:
where the definitions of the variables Q,...
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7524516 |
Corrosion inhibiting mildew remover kit
The corrosion inhibiting mildew remover kit includes a premeasured amount of sodium perborate, a premeasured amount of a liquid inhibitor and a premeasured amount of a liquid blend. The premeasured...
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7494670 |
Composition and process for removing and preventing mildew and fungal growth
This invention comprises a composition and the process of using the composition for removing and preventing mold, mildew, and fungal growth. The composition comprises at least one alkali metal...
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7473711 |
Androgen modulators
The present invention is directed to a class of 4-cyano-phenoxy derivatives of formula I and to their use as androgen receptor modulators. Other aspects of the invention are directed to the use of...
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7432306 |
Method for preparing novel transcription factors and use
The present invention has an object to develop novel compounds which are effective for the therapy of syndrome X, cancer, myxedema, vascular chronic inflammation and the like, and furthermore...
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7420003 |
Compounds and a novel process for their preparation
The present invention is directed to a procedure for making an enantiomerically enriched compound containing a hydronaphthalene ring structure. The process involves reacting oxabenzonorbornadienes...
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7351744 |
Naphthalene derivatives as termite repellents and toxicants
Several derivatives of naphthalene, including 1′-acetonaphthone, 2′-acetpnaphthone, 1-methoxynaphthalene, and 2-methoxynaphthalene, were discovered to be effective toxicants and repellents of...
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7312249 |
Vitamin D analogues
Novel biaromatic vitamin D analogues have the general formula (I):
and are suited for a wide variety of pharmaceutical applications, whether in human or veterinary medicine, and also for...
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7307071 |
RAF-MEK-ERK pathway inhibitors to treat cancer
Materials and methods for treating certain cancers are described, preferably cancers that result from the up-regulation of the RAF-MEK-ERK pathway, and more preferably chronic myelogenous leukemia,...
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7157419 |
Growth factor binding molecules
Growth factor binding molecules having a plurality of peptide loops attached to a non-peptide organic scaffold, preferably having pseudo-six amino acid peptide loops with four amino acid...
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7109164 |
Aniline-derived ligands for the thyroid receptor
New thyroid receptor ligands are provided which have the general formula
in which:
X is —O—, —S—, —CH 2 —, —CO—, or —NH—; Y is —(CH 2 ) n — where n is an integer...
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7109161 |
Preserved pharmaceutical formulations
The present invention is directed to the use of benzethonium chloride, alone or in combination with phenoxyethanol or phenyl ethyl alcohol, to provide anti-microbial activity in pharmaceutical...
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7101915 |
P-terphenyl compounds
The present invention provides a selective suppressor of the IgE production comprising a compound which suppresses the IgE production in a process from a differentiation of a mature B cell into an...
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7091186 |
p-Amidobenzylethers in drug delivery agents
Compounds of the formulae
L A n -Z-X—W w D and B Z-X—W w D
wherein: D is...
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7056862 |
Herbicide potentiators
The invention provides an agricultural chemical enhancer and an agricultural chemical composition which are safely used for crops without any phytotoxicity, have a potency enhancing action on...
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7030162 |
Treatment of migraine headache
The invention is directed to pharmaceutical compositions useful in the treatment of migraine. The compositions contain metoclopramide and one or more NSAIDs in unit dosage form. By selecting NSAIDs...
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7029706 |
Composition for the treatment of cutaneous mycosis
The inventions relates to the use of silica in the formulation of antifungal composition for the treatment of cutaneous mycoses, and method to manufacture an antifungal powder with boric acid and...
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7012071 |
Compounds for the treatment of metabolic disorders
Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and...
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6949586 |
Synergistic composition of trans-tetracos-15-enoic acid and Apocynin and method of treatment for hepatotoxicity
The present invention relates to a synergistic hepatoprotective pharmaceutical composition comprising an effective amount of trans-tetracos-15-enoic acid (TCA) and Apocynin (APO), the present...
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6933322 |
Substituted naphthylenes for the treatment of non-insulin dependent diabetes mellitus
This invention provides compounds of formula I, having the structure
wherein R 1 , R 4 , A, and Z are as defined in the specification, or a pharmaceutically acceptable salt thereof, that are...
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6930131 |
Aryl substituted 3-ethoxy phenyl trifluoromethane sulfonamides for the treatment of non-insulin dependent diabetes mellitus (NIDDM)
This invention provides compounds of formula I, having the structure
wherein R 1 , R 2 , R 3 , R 4 , A, and B are as defined in the specification, or a pharmaceutically acceptable salt...
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6921777 |
Heteroethynylenic compounds and pharmaceutical and cosmetic compositions containing them
The invention relates to novel heteroethynylenic compounds having the general formula (I):
as well as to the use of these compounds in pharmaceutical compositions intended for use in human or...
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6846837 |
Topical administration of basic antifungal compositions to treat fungal infections of the nails
Methods and topical pharmaceutical formulations are provided for the treatment of nail fungus (onychomycosis). The invention involves a pharmacologically active antifungal agent, plus a...
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6800605 |
Aniline-derived ligands for the thyroid receptor
New thyroid receptor ligands are provided which have the general formula in which: X is —O—, —S—, —CH 2 —, —CO—, or —NH—; Y is —(CH 2 ) n — where n is an integer from 1...
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6797694 |
Chemical compounds having ion channel blocking activity for the treatment of immune dysfunction
The present invention relates to chemical compounds having inhibitory activity on an intermediate conductance Ca 2+ activated potassium channel (IK Ca ), and the use of such compounds for the...
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6787573 |
Antiviral therapy
The invention relates to the field of antiviral agents, and more specifically to antiviral therapy. The invention provides use of at least one compound or mixture of compounds of the general...
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6660768 |
Parasiticidal compositions and methods of use
A solvent system for pyrethroids and pyrethrins comprises a terpene or a terpene derivative such as a terpene alcohol, aldehyde or ketone. In a preferred embodiment, the solvent system further...
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6660288 |
Insect repellents
The use of specific perfume ingredients, e.g. tricyclodecenyl allyl ether, to repel insects. The perfume ingredients may be used in a composition comprising from 0.1 to 40 percent by weight of one...
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6646013 |
Nutrient formulations for disease reduction
The instant invention provides a combination of multiple nutrients useful to reduce colon rectal cancer in a mannalian or human subject. Further, the combination provides synergistic ratios of the...
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6645978 |
Lipoxin A4 and its analogs for the treatment of dry eye
Ophthalmic compositions containing Lipoxin A 4 and its analogs and methods of their use for treating dry eve are disclosed.
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6641800 |
Pressurized aerosol compositions comprising powdered medicament dispersed in hydrofluoroalkane
Pressurized aerosol composition for administration by inhalation comprising a liquefied hydrofluoroalkane, a powdered medicament dispersed therein, and a suspending agent comprising a polymer...
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6638969 |
Combinations of ileal bile acid transport inhibitors and fibric acid derivatives for cardiovascular indications
The present invention provides combinations of cardiovascular therapeutic compounds for the prophylaxis or treatment of cardiovascular disease including hypercholesterolemia, atherosclerosis, or...
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6627664 |
Perylenequinones for use as sonosensitizers
The invention is perylenequinones that are both sonosensitizers and photosensitizers, and their therapeutic use.
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6624197 |
Diphenylethylene compounds
Novel diphenylethylene and styrenes are provided which are administered orally to decrease blood glucose levels in rats. The glucose tolerance in insulin resistant rats is also shown, as well as...
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6620854 |
Surface-active preparations
There are described surface-active soap compositions containing (a) from 0.01 to 2% by weight of an antimicrobial active ingredient from the class of diphenyl ethers, (b) from 0.1 to 30% by weight...
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6585989 |
Mixtures of phenolic and inorganic materials with antimicrobial activity
Plastic films, fibers and articles are provided long-term antimicrobial activity with a combination of certain phenolic and inorganic antimicrobial agents. The plastic films, fibers and articles...
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6566397 |
Acyclic isoprenoid ether derivatives as chemotherapeutics
A method of and compositions for suppressing the growth of tumor cells in a patient are disclosed. In one embodiment, the method comprises treating the patient with an effective amount of an...
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6552088 |
Biphenyl derivatives
Biphenyl substituted amides with activity as antagonists of the neurokinin 1 (NK-1, substance P) receptor.
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6506800 |
1,4 diaryl-2,3-difluoro-2-butene insecticidal and acaricidal agents
Pesticidal 1,4-diaryl-2,3-difluoro-2-butene compounds of formula I wherein Ar is phenyl, 1- or 2-naphthyl or a 5- or 6-membered heteroaromatic ring all of which aromatic systems may be...
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6500416 |
Pesticide
There are described a flowable composition for controlling harmful insects and representatives of the order Acarina, comprising at least one pesticidally active compound, one or more signal...
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6465421 |
Modulating body/cranial hair growth
The growth of body and/or head/cranial hair on mammalian organisms, for example humans, is modulated by administering thereto, whether topically and/or systemically, therapeutically effective...
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6444709 |
Heteroethylene compounds and pharmaceutical and cosmetic compositions containing same
The invention relates to novel heteroethynylenic compounds having the general formula (I): as well as to the use of these compounds in pharmaceutical compositions intended for use in human or...
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6444230 |
Synergistic composition of peracetic acid and amine oxide
Composition in the form of an aqueous solution, useful for disinfecting hard surfaces comprises: a) from 0.0005% to 20% by weight of peracetic acid, b) from 0.001% to 45% by weight of acetic acid,...
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6440406 |
Attractant for monitoring and control of adult scarabs
The present invention provides a composition for attracting scarabs. Liquid and solid formulations are provided, along with methods for their use, for controlling or eliminating scarabs, and/or...
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6399072 |
Method of preparing and using isoflavones for the treatment of alcoholism
A composition is prepared by extracting phytochemicals from plant matter for treatment of alcohol dependency. This composition is enriched preferably with two or more fractions of plant matter,...
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6395279 |
Method of preparing and using isoflavones for the treatment of cancer
A composition is prepared by extracting phytochemicals from plant matter and is administered to provide treatment for cancer and especially for breast, prostate, skin, colon, urinary and bladder...
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6391310 |
Method of preparing and using isoflavones for the treatment of neurological symptoms
A composition is prepared by extracting phytochemicals from plant matter and is administered to provide treatment for mental conditions and nerve problems, especially neurological symptoms,...
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6391309 |
Method of preparing and using isoflavones for the treatment of female symptoms
A composition is prepared by extracting phytochemicals from plant matter to form a dietary supplement for treatment of female symptoms. This composition is enriched preferably with two or more...
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6391308 |
Method of preparing and using isoflavones for the treatment of blood related illnesses
A composition is prepared by extracting phytochemicals from plant matter and is administered to provide treatment for cardiovascular medical conditions, such as: excessive bloodstream cholesterol,...
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