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7595347 |
Method for protecting normal cells from cytotoxicity of chemotherapeutic agents
Pre-treatment with α,β unsaturated aryl sulfones protects normal cells from the cytotoxic side effects of two classes of anticancer chemotherapeutics. Administration of a cytoprotective sulfone...
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7589056 |
Agent for the prevention and treatment of sexually transmitted diseases-I
Use of a polylysine, polyamidoamine or polypropylenimine dendrimer having naphthyl disulphonate terminal groups as a topically applied agent in prophylaxis or treatment of sexually transmitted...
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7585887 |
Active agent combinations with insecticidal and acaricidal properties
The invention relates to novel active compound combinations having very good insecticidal and acaricidal properties and containing
(a) cyclic ketoenols having the formula
in which the groups...
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7517901 |
p38 MAP kinase inhibitors and methods for using the same
Compounds of formula Ia or Ib:
wherein X and Y are nitrogen or CR e , and R 1 , R 2 , R 3 , R 4 and R 5 are as defined herein. Also disclosed are methods of making the subject compounds and...
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RE40640 |
Injectable microfoam containing a sclerosing agent
Injectable microfoam for scleroteraphy. The sclerotherapy of varices is based on the injection of liquid substances capable of suppressing them. The present invention relates to the preparation of...
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7476767 |
Alpha-hydroxy sulfonate aldehydes, germicidal compositions containing the alpha-hydroxy sulfonate aldehydes, or mixtures of alpha-hydroxy sulfonate aldehydes and phthalaldehydes, and methods of using the compounds or compositions for disinfection or sterilization
Disclosed herein are α-Hydroxy sulfonate aldehydes and synthesis methods therefor. Germicidal compositions including the α-hydroxy sulfonate aldehydes, are also disclosed. In one aspect, a...
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7411004 |
Sulphones which modulate the action of gamma secretase
Disclosed are sulphones which modulate the action of gamma-secretase. The compounds are useful in the treatment or prevention of Alzheimer's disease.
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7306811 |
Fungicide composition based on halosulphone in particular for packaging
A packaging sheet comprising a mixture
of compound A
where R 1 may be an alkyl, alkoxy or alkylene radical having 1 to 6 carbon atoms; X 1 and X 2 , identical or...
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7300673 |
Deposition products, composite materials and processes for the production thereof
Methods for the production of deposition products including an oxidized metal species under both acidic and alkaline conditions, methods for the production of composite materials including a...
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7276539 |
3-Phenyl-2-arylalkylthiopropionic acid derivatives as selective agonists of ppar-alpha
A compound of formula I
wherein R 1 represents chloro, fluoro or hydroxy as well as optical isomers and racemates thereof as well as pharmaceutically acceptable salts, prodrugs, solvates and...
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7235590 |
Use of treosulfan and derivatives thereof for treating multiple sclerosis
The invention relates to the use of treosulfan and/or derivatives thereof for producing a pharmaceutical composition used in the treatment of multiple sclerosis.
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7115632 |
Sulfonyl aryl or heteroaryl hydroxamic acid compounds
A sulfonyl aromatic or heteroaromatic ring hydroxamic acid compound that inter alia inhibits matrix metalloprotease activity is disclosed as are a treatment process that comprises administering a...
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7081469 |
Benzimidazole vascular damaging agents
Vascular damaging agents composed of substituted 5(6)-substituted benzimidazole-2-carbamates are provided. These agents are useful in the preparation of medicaments for the treatment of diseases...
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7074829 |
Antiestrogens, process for their production and their pharmaceutical use
This invention relates to new antiestrogens of the general formula
in which the substituents have the meanings that are explained in more detail in the description.
The new compounds are a)...
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7067538 |
MCP-1 receptor antagonists and methods of use thereof
The present invention relates to sulfones that are useful in the treatment of chemokine-mediated disorders. In certain embodiments, the present invention concerns the compounds that are MCP-1...
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7045152 |
Treating pulmonary disorders with gaseous agent causing repletion of GSNO
Pulmonary disorders in which the GSNO pool or glutathione pool in the lung is depleted and where reactive oxygen species in lung are increased, are treated by delivering into the lung as a gas,...
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7034015 |
Aminobenzoephenones
The invention relates to a novel class of aminobenzophenones derivatives, to pharmaceutical preparations comprising said compounds, to dosage units of such preparations, to methods of treating...
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6969533 |
Beverage and additive for inflamed tissue
The invention is a beverage involving an ingestible fluid and a dosage amount of an ingestible composition for treating an inflammatory tissue in a mammal, involving the inflammatory tissue...
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6881424 |
Highly acidic metalated organic acid
A highly acidic metalated organic acid composition and its preparation. The acidic composition can be prepared by mixing a monovalent or polyvalent cation and an organic acid in the presence of a...
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6833359 |
Method for treating soil for the control of soil borne plant pathogens
A method for reducing bacterial and fungal soil pathogens which comprises applying to a soil a chemically effective amount of a lignosulfonate, the amount preferably being between 0.05% and about...
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6803057 |
Hydrogen peroxide disinfectant with increased activity
An acidic aqueous hydrogen peroxide solution is provided with improved disinfectant activity. Concentrated solutions preferably contain up to about 8 wt./wt. % H2O2 and as-used concentrations...
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6790463 |
Uses of targeted oxidative therapeutic formulation in arteriosclerosis
The use of a pharmaceutical formulation in treating coronary arteriosclerosis and a two-component pharmaceutical formulation. The pharmaceutical formulation contains peroxidic species or reaction...
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6787573 |
Antiviral therapy
The invention relates to the field of antiviral agents, and more specifically to antiviral therapy. The invention provides use of at least one compound or mixture of compounds of the general...
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6770677 |
Synergistic mixtures of Bis (Trichloromethyl) Sulfone and 1,2-dibromo-2,4-dicyanobutane
Combinations of Bis (Trichloromethyl) Sulfone and 1,2-dibromo-2, 4-dicyanobutane are shown to have synergistic antimicrobial properties. Preferred compositions use the two components in ratios of...
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6767926 |
Method for protecting normal cells from cytotoxicity of chemotherapeutic agents
Pre-treatment with α,β unsaturated aryl sulfones protects normal cells from the cytotoxic side effects of two classes of anticancer chemotherapeutics. Administration of a cytoprotective sulfone...
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6749869 |
Acidic aqueous chlorite teat dip providing shelf life, sanitizing capacity and tissue protection
The mastitis control teat dip composition of the invention provides rapid initial kill, a useful highly pseudoplastic rheology, a barrier/film-forming capacity, a unique antimicrobial composition...
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6719988 |
Antiseptic compositions for inactivating prions
An antiseptic composition useful in destroying the infectivity of infectious proteins such as prions is disclosed. The antiseptic composition is preferably maintained at a pH of 4.0 or less which...
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6706290 |
Methods for eradication of nanobacteria
Nanobacteria contribute to pathological calcification in the human and animal body, including diseases such as kidney stones, salivary gland stones, dental pulp stones and atherosclerosis. The...
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6699884 |
Fluoro-substituted benzenesulfonyl compounds for the treatment of inflammation
Methods of treating cyclooxygenase-2 mediated disorders comprising administering to a subject a therapeutically effective amount of one or more fluoro-substituted benzenesulfonyl compounds...
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6699510 |
Acidic aqueous chlorite teat dip with improved visual indicator stability, extended shelf life, sanitizing capacity and tissue protection
The mastitis control teat dip composition having a visible indicator aspect of the invention provides a softening, soothing, smoothing, relaxing property, a rapid initial kill, a useful highly...
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6692757 |
Multi-component, safe biocidal complex
A novel composition has been discovered for decontaminating biofilm-contaminated surfaces (the “Biocidal Complex”). The novel composition both kills bacteria and destroys at least a part of the...
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6670401 |
Polysubstituted indan-1-ol compounds, and methods for their preparation and use
Polysubstituted indan-1-ol compounds, methods for their preparation; and methods for their use are disclosed herein. In particular, the invention relates to polysubstituted indan-1-ol compounds of...
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6667346 |
Method for protecting cells and tissues from ionizing radiation toxicity with α, β unsaturated aryl sulfones
Pre-treatment with α,β unsaturated aryl sulfones protects normal cells from the toxic side effects of ionizing radiation. Administration of a radioprotective α,β unsaturated aryl sulfone...
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6663874 |
Composition to alleviate pain and topical method of applying same
A composition for use by animals, including humans, to alleviate pain and/or inflammation around a painful joint, joint replacement surgery site, muscle, tendon, and/or ligament. A method to...
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6660308 |
Beverage and additive for the ill
The invention is a beverage made of a fluid and a one time daily dosage amount in an ingestible amount for treating an inflammatory tissue or arthritic condition in a mammal involving tissue that...
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6617356 |
Gel system for oral and topical administration of water insoluble and/or water intolerant drugs and supplements
Suspensions, emulsions or dispersions of therapeutically active agents which are water insoluble or water intolerant such as nutritional supplements, herbal products, drugs, bacteria, yeast,...
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6608061 |
Bisaryl compound and medicament for cancer treatment comprising the same
A medicament for treatment of cancer comprising a compound represented by the following general formula (I) or a physiologically acceptable salt thereof: Ar 1 —S—R 1 —S—Ar 2 wherein R 1 ...
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6593347 |
Nitrosated and nitrosylated nonsteroidal antiinflammatory compounds, compositions and methods of use
The present invention describes novel nitrosated and/or nitrosylated nonsteroidal antiinflammatory compounds, and novel compositions comprising at least one nitrosated and/or nitrosylated...
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6586014 |
Liquid dish cleaning compositions containing hydrogen peroxide
An antibacterial liquid dish cleaning composition with desirable cleansing and de-staining properties comprising a C 8-18 ethoxylated alkyl ether sulfate, two anionic surfactant, a betaine...
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6583178 |
Antibacterial liquid dish cleaning compositions having improved viscosity
An antibacterial liquid dish cleaning composition with desirable cleansing properties comprising a C 8-18 ethoxylated alkyl ether sulfate, two anionic surfactant, a betaine surfactant, a hydroxy...
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6559181 |
Antiestrogens, process for their protection and their pharmaceutical use
This invention relates to new antiestrogens of the general formula in which the substituents have the meanings that are explained in more detail in the description. The new compounds are a) pure...
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6548085 |
Insecticidal compositions and method of controlling insect pests using same
A synergistic insecticide is provided by the addition of sodium lauryl sulfate or lecithin to an essential oil, preferably an essential oil which has been deregulated by the Environmental...
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6469040 |
Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of neoplasia
This invention relates to the use of cyclooxygenase-2 inhibitors or derivatives thereof in preventing and treating neoplasia. In particular, the invention describes the method of preventing and...
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6444709 |
Heteroethylene compounds and pharmaceutical and cosmetic compositions containing same
The invention relates to novel heteroethynylenic compounds having the general formula (I): as well as to the use of these compounds in pharmaceutical compositions intended for use in human or...
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6440391 |
Management of snoring by oral administration of dimethyl sulfone
A method of managing snoring is provided by the instillation orally of a solution containing 1-20% methylsulfonylmethane by weight dissolved in water so as to cover the mucous membranes of the...
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6403630 |
Treating cancers associated with overexpression of HER-2/neu
Cancers associated with overexpression of HER-2/neu are treated with a selective inhibitor of cyclooxygenase-2 as the sole treating agent or said inhibitor in combination regimen with HERCEPTIN®...
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6399106 |
Method for maintaining freshness of cut flower
A method for maintaining the freshness of a cut flower is disclosed. The method comprises the step of causing a flowering plant to imbibe an aqueous solution of a composition for maintaining the...
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6397102 |
Device and method for photoactivated drug therapy
A device and method are presented wherein a common drug for a particular treatment is given to the patient in an inactive form. The drug can be administered systemically or topically. The activity...
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6355633 |
Aryl sulfonic acids and derivatives as FSH antagonists
This invention provides compounds of formula I having the structure wherein R 1 , Ar, Ar′, and Q are as defined in the specification, or a pharmaceutically acceptable salt thereof, which are...
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6346279 |
Hydrogen peroxide disinfectant with increased activity
An acidic aqueous hydrogen peroxid solution is provided, with improved disinfectant activity. Concentrated solutions preferably contain up to about 8% and as-used concentrations contain about 0.5%...
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