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7432305 |
Tail variants of redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers
Methods of treating or suppressing mitochondrial diseases, such as Friedreich's ataxia (FRDA), Leber's Hereditary Optic Neuropathy (LHON), mitochondrial myopathy, encephalopathy, lactacidosis,...
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7410656 |
Anti-cancer compounds
This invention relates to a compound or group of compounds present in an active principle derived from plants of species Euphorbia peplus, Euphorbia hirta and Euphorbia drummondii , and to...
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7230033 |
Pest control compositions and methods for their use
Compositions and methods for controlling an arthropod pest population that include an eremophilane sesquiterpene pest control agent (such as, nootkatone or 13-hydroxy-valencene) and a...
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7202279 |
Cyclic dipeptides and azetidinone compounds and their use in treating CNS injury and neurodegenerative disorders
The present invention provides 4-substituted-2-azetidinone compounds, bicyclic 2-5-diketopiperazine compounds, and pharmaceutical compositions thereof that are potent, safe and effective...
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7060686 |
Anti-inflammatory compounds derived from Pseudopterogorgia elisabethae
Methods for treating, preventing, or inhibiting diseases and disorders associated with inflammation, cell-proliferation, and pain comprising the administration of a compound having the structural...
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7001611 |
Compositions normalizing circadian rhythm
The present invention provides a circadian rhythm normalizing composition containing astaxanthin and/or its ester as an active ingredient, and a composition having the action of enhancing the...
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6979688 |
Treatment method against side-effects of chemotherapy
A method and composition is provided for organ rescue wherein a specific counter-measure is applied locally to a tissue at risk for or exhibiting an adverse side effect of a cancer treatment. More...
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6908918 |
Antitumor agents
The present invention provides compounds of general formula I or II:
wherein R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , and R 7 have any of the values defined in the specification, and...
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6906108 |
Extracts of vetiver oil as repellent and toxicant to ants, ticks, and cockroaches
Extracts of vetiver oil were found to be significant repellents and toxicants of ants, ticks, and cockroaches. Nootkatone was shown to significantly decrease ant invasion and increase mortality in...
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6897244 |
Dihydronootkatone and tetrahydronootkatone as repellents to arthropods
Two derivatives of nootkatone, tetrahydronootkatone and 1,10-dihydronootkatone, are surprisingly effective as repellents of termites and mosquitos. Tetrahydronootkatone and 1,10-dihydronootkatone...
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6890960 |
Vetiver oil extracts as termite repellent and toxicant
Extracts of vetiver oil were found to significantly repel termites. In one extract, nootkatone was isolated and found to be a significant repellent and toxicant of termites. Nootkatone...
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6844013 |
Methods of stimulating the immune system
This invention relates to a compound or group of compounds present in an active principle derived from plants of species Euphorbia peplus, Euphorbia hirta and Euphorbia drummondii , and to...
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6706760 |
Wasp controlling agent
A wasp controlling liquid formulation, which comprises a pesticidal compound as an active ingredient and at least 30% by weight of a saturated hydrocarbon that has a boiling point from 90° C. to...
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6635672 |
Agent for lowering prolactin
The present invention relates to a prolactin lowering drug containing at least one bicyclic diterpene of the labdane or clerodane type: wherein R1=H, C 1 to C 3 alkyl or C 1 to C 3 acyl.
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6630515 |
Urinary incontinence therapy
The invention includes a method of treating neurogenic urinary dysfunction that comprises contacting urinary bladder mucosa of a patient afflicted with neurogenic urinary dysfunction with an...
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6562782 |
Oligocycloalkanoid compounds and methods of use
The present invention related to an oligocycloalkanoid compound comprising formula (I) wherein m, n, and o are independently an integer from 0 to 2; A 1 through A 10 are independently a direct...
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6559184 |
Methods and compositions for treating male erectile dysfunction
Administration of a pharmaceutical composition in the form of a suppository comprising: (a) a prostaglandin vasodilator; (b) 15-hydroxyprostaglandindehydrogenase inhibitor: and (c) a base material...
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6451844 |
Use of menthyl-2 pyrrolidone-5-carboxylate as an insect repellent
The use of menthyl 2-pyrrolidone-5-carboxylate as an insect repellent, usually by application to a substrate or into an air space. The menthyl 2-pyrrolidone-5-arboxylate can be used as a...
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6444662 |
Stable hyperforin salts, method for producing same and their use in the treatment of alzheimer's disease
Described are salts of hyperforin and adhyperforin of formula I [A − ] m [B] p+ (I) wherein m is an integer from 1 to 3, p is equal to m and gives the total number of positive charges of the...
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6433025 |
Method for retarding and preventing sunburn by UV light
Astaxanthin is a potent antioxidant, over 500 times more powerful than Vitamin E and 10 times stronger than other carotenoids such as zeaxanthin, lutein, canthaxanthin and beta-carotene....
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6352703 |
Compositions and methods for detecting and killing termites
Significant concentrations of naphthalene were detected in carton nests of Formosan subterranean termites, Coptotermes formosanus Shiraki, collected from Florida, Hawaii, and Louisiana. This is...
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6335015 |
Method of the prophylactic treatment of mastitis
A method of prophylactic treatment of mastitis in mammalian, including human, mothers, is described. The method comprises administration of a prophylactically effective dosage of a human or...
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6329414 |
Histidine containing nutriceutical
Nutriceutical compositions useful as a dietary supplement which have antioxidant/free radical scavengers and also having a cytoprotective effect are disclosed. The compositions contain a...
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6328986 |
Method of deterring birds from plant and structural surfaces
A method for deterring birds from perching, roosting or loafing on plant and structural surfaces by applying to the surfaces a non-toxic composition. The non-toxic composition is one that triggers...
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6300376 |
Indane dimer compounds and their pharmaceutical use
Indane dimer compounds and their pharmaceutical use particularly to achieve smooth muscle relaxing activity and/or mast cell stabilizing activity and/or anti-inflammatory activity are described.
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6277417 |
Method of inhibiting 5α-reductase with astaxanthin
A method for inhibiting the activity of the enzyme 5α-reductase in a human subject is provided which comprises administering to the subject a composition comprising the carotenoid astaxanthin....
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6274570 |
Pesticidal compositions
A liquid pesticidal composition, which is substantially free of water, comprising a hydrophobic pesticide or mixture of pesticides dissolved in an organic solvent and comprising as surfactants (a)...
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6265450 |
Anti-stress composition
An anti-stress composition having for its active ingredient astaxanthin and/or its ester. This composition can be in the form of a pharmaceutical, functional food, food or beverage and so forth.
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6258855 |
Method of retarding and ameliorating carpal tunnel syndrome
Astaxanthin is a potent antioxidant, over 500 times more powerful than Vitamin E and 10 times stronger than other carotenoids such as zeaxanthin, lutein, canthaxanthin and beta-carotene....
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6245818 |
Medicament for improvement of duration of muscle function or treatment of muscle disorders or diseases
Medicament for the prophylactic and/or therpeutic improvement of the duration of mammalian muscle function and/or treatment of mammalian muscle disorders or diseases, e.g. equine Exertional...
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6218434 |
Use of the naturally-occurring quinones thymoquinone and dithymoquinone as antineoplastic and cytotoxic agents
Nigella sativa derivatives, thymoquinone (TM) and dithymoquinone (DIM) are used in treatment of parental and multi-drug resistant human cancers.
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6174545 |
Drug delivery devices and process of manufacture
An improved process for manufacturing transdermal drug delivery devices and devices made therefrom. The invention provides a heat equilibration process for the manufacture of drug delivery devices...
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6153216 |
Transdermal estradiol/progestogen agent patch and its production
The invention concerns a transdermal patch for the release through the skin of estradiol and a progestogen agent and a process for its production.
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6103765 |
Methods for treating male erectile dysfunction
Administration of a pharmaceutical composition comprising: (a) a vasodilator; and (b) a 15-hydroxyprostaglandindehydrogenase inhibitor is effective for the treatment of male erectile...
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6001874 |
Arthropod control composition for plant protection
A non-toxic arthropod control composition is disclosed for application to foliage for plant protection. The composition includes behavior interfering compounds, agricultural oil and/or surface...
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5929124 |
Antimicrobial diterpenes
Antimicrobial diterpenes and methods of using them.
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5889049 |
Use of terpene compounds for reduced release of arachidonic acid and of inflammation mediators
Disclosed is a method of treatment of steroid requiring inflammatory diseases using certain saturated monocyclic and bicyclic terpene compounds. These compounds may be administered in the form of...
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5863953 |
Liquid, oil-miscible carotenoid preparations
Liquid, oil-miscible carotenoid preparations which, as double dispersion systems, comprise an aqueous-disperse phase which has a particle diameter of less than 100 μm and in which particles,...
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5730960 |
Benzylidenenorcamphor derivatives
The use of a benzylidenenorcamphor compound of the formula I ##STR1## wherein Phe is a phenyl group which is unsubstituted or substituted by 1 to 5 hydroxyl, alkyl or alkoxy groups having 1 to 10 C...
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5691386 |
Triterpenoid compound for the treatment of diabetes
A novel hypoglycemically active triterpenoid compound isolated in purified, preferably substantially purified, form from Salacia spp., processes for obtaining the novel triterpenoid compound,...
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5674902 |
Method of inhibiting hyperplasia to a mammal in need thereof
The present invention relates to a method of inhibiting a protein kinase C-mediated biological response, such as, hyperplasia. The method comprises administering to a mammal a non-tumor promoting...
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5629045 |
Biodegradable nosiogenic agents for control of non-vertebrate pests
Fouling of marine structures such as boats by shell bearing sea animals which attach themselves to such structures, such as barnacles, is inhibited by coatings containing lipid soluble, non-toxic,...
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5580857 |
Use of gibberellins for the treatment of prostatitis
The use of active gibberellins for the preparation of a pharmaceutical composition for the treatment of prostatitis. The method results in a decrease in prostate mass.
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5576355 |
Diamondoid derivatives for pharmaceutical use
A method of inhibiting viruses in which a virus is contacted with diamondoid alcohol, ketone, ketone derivative, adamantyl amino acid, quaternary salt or combinations thereof which have antiviral...
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5563176 |
Illudin analogs useful as antitumor agents
Antineoplastic illudin analogs are provided of the formula: wherein R 4 , R 5 and R 6 are (C 1 -C 4 )alkyl, Y is H, (C 1 -C 3 )alkyl, (R 4 )R 5 )(R 6 )Si or alkanoyl ((C 1 -C 4 )alkylC(O))...
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5538983 |
Method of treating amyloidosis by modulation of calcium
Various first messengers linked to phospholipase C, including acetylcholine and interleukin-1, regulate the production both of the secreted form of the amyloid protein precursor and of amyloid...
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5482970 |
Transdermal antiandrogenic compositions and modulated process
Novel compositions comprising an antiandrogenic compound of the formula ##STR1## wherein R is COR 1 wherein R 1 is loweralkyl and a vehicle comprising a metabolism modulator and a polar organic...
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5468770 |
Green leaf volatiles as inhibitors of bark beetle aggregation pheromones
A composition for preventing or limiting the attack and infestation of trees by pine bark beetles, by inhibiting the response of the beetles to their aggregation pheromones. The composition...
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5441987 |
Antifungal agent
A compound having the formula ##STR1## which is useful as an antifungal agent and for the treatment and control of several agricultural phytopathogens, including Phytophthora infestans, is disclosed.
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5439942 |
Method of treating certain tumors using illudin analogs
A method of inhibiting certain tumor cell growth in a subject is provided comprising contacting the tumor with a therapeutic amount of an illudin S or illudin M analog having the structure ##STR1##...
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