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7601876 |
Compounds, compositions and methods for the treatment of amyloid diseases such as systemic AA amyloidosis
Bis- and tris-dihydroxyaryl compounds and their methylenedioxy analogs and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the...
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7598294 |
3,4-methylenedioxy-substituted chalcones as therapeutic agents
The present invention pertains to the use of a compounds for the manufacture of a medicament for use in the treatment of a proliferative condition, wherein the compounds have the following formula:...
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7402706 |
Polyisoprenylated benzophenones and their isomers as inhibitors of histone acetyltransferases and uses thereof
In this patent we describe the purification of prenylated benzophenones from the fruit rinds of Garcinia species and its evaluation as an inhibitor for Histone acetyltransferases p300 and PCAF....
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7326734 |
Treatment of bladder and urinary tract cancers
Compositions of matter and methods wherein chalcone and flavone derivatives are administered to human or veterinary patients for the treatment of bladder or urinary tract cancer. Compounds of the...
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7256219 |
Multifluoro-substituted chalcones and analogs as activators of caspases and inducers of apoptosis and the use thereof
The present invention is directed to multifluoro-substituted Chalcones and analogs thereof, represented by the general Formula I:
wherein Ar and R 6 -R 10 are defined herein. The present...
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7101910 |
Compounds for the treatment of metabolic disorders
Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and...
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7056952 |
Isoflavone metabolites
There are disclosed compounds of formulae (I) or (II) in which A is selected from the group consisting of (1), (2), (3) and (4); OH, and one of R 1 and R 2 is selected from H, OH and OCH 3 , and...
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7030162 |
Treatment of migraine headache
The invention is directed to pharmaceutical compositions useful in the treatment of migraine. The compositions contain metoclopramide and one or more NSAIDs in unit dosage form. By selecting NSAIDs...
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6984389 |
Using heat shock proteins to improve the therapeutic benefit of a non-vaccine treatment modality
The present invention relates to methods of improving a treatment outcome comprising administering a heat shock protein (HSP) preparation or an α-2-macroglobulin (α2M) preparation with a...
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6906059 |
Pharmaceutical composition with protective action against oxidative/toxic substances, especially cardiotoxic substances
The use of benzazepin-N-acetic acid derivatives which contain an oxo group in the a position to the nitrogen atom and are substituted in the 3 position by a...
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6828347 |
Anti-viral multi-quinone compounds and regiospecific synthesis thereof
This invention provides various biquinone and trimeric quinone derivatives. The invention also provides a method for synthesis of a multi-quinone compound including reacting a hydroxyquinone anion...
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6790463 |
Uses of targeted oxidative therapeutic formulation in arteriosclerosis
The use of a pharmaceutical formulation in treating coronary arteriosclerosis and a two-component pharmaceutical formulation. The pharmaceutical formulation contains peroxidic species or reaction...
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6774111 |
Carbohydrate system and a method for providing nutrition to a diabetic
The two carbohydrate mixture of this invention utilizes a source of fructose in combination with at least one readily digestible glucose polymer source. The addition of the fructose significantly...
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6462075 |
Chalcone and its analogs as agents for the inhibition of angiogensis and related disease states
The present invention relates to chalcone and chalcone derivatives and analogs which are useful as angiogenesis inhibitors. The present compounds, which are inexpensive to synthesize, exhibit...
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6455032 |
Composition and method for protecting skin from UV induced immunosuppression and skin damage
Compositions and a method of protecting skin from either UV-induced immunosuppression or from UV-induced skin damage using a composition containing an extract of soy or clover, and/or the...
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6416773 |
Cosmetic or dermatological light protection agent preparations
The invention relates to cosmetic or dermatological preparations comprising a) 0.1 to 10% by weight of one or more 3,3-diphenylacrylates of the formula I, and b) 0.1 to 10% by weight of one or...
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6413998 |
Compositions and methods for treating bone deficit conditions
Compounds containing two aromatic systems covalently linked through a linker containing one or more atoms, or “linker” defined as including a covalent bond per se so as to space the aromatic...
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6391921 |
Treatment of inflammation with 2,4,6-trihydroxy-α-para-methoxyphenylacetophenone, or its pharmaceutically acceptable derivatives
2,4,6-trihydroxy-α-p-methoxyphenylacetophenone (also identified herein as “D-58”), or its pharmaceutically acceptable derivatives such as salt and ester forms, is administered for inhibiting...
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6248790 |
Treatment of inflammation with 2,4,6-trihydroxy-alpha-rho-methoxyphenylacetophenone, or its pharmaceutically acceptable derivatives
2,4,6-trihydroxy-α-p-methoxyphenylacetophenone (also identified herein as "D-58"), or its pharmaceutically acceptable derivatives such as salt and ester forms, is administered for inhibiting...
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6235773 |
Compositions for regulating skin appearance
The present invention relates to methods for preventing or treating skin disorders using flavonoid compounds. The present invention also relates to methods for regulating skin condition.
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6218435 |
Reduction of hair growth
A method of reducing hair growth in a mammal includes applying, to an area of skin from which reduced hair growth is desired, a dermatologically acceptable composition containing a suppressor of...
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RE37087 |
Insecticidal triffluormethyl alkane derivatives
There are provided new alkane and alkoxyalkane derivatives of the general formula I ##STR1## in which R 1 , R 2 , R 3 , R 4 and A have the meanings given in the description, processes for their...
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6187822 |
Wound treatment through inhibition of adenosine diphosphate ribosyl transferase
The present invention pertains to a method for healing a wound in a mammal which comprises the steps of (A) providing a therapeutic wound healing composition comprising a therapeutically effective...
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6127422 |
Anti-viral method
A method of inhibiting an envelope virus selected from the group consisting of influenza bovine diarrheal, hepatitis C and tick borne encephalitis virus that udergoes hemagglutinin-mediated fusion...
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6093408 |
Skin care compositions
The present invention provides compositions and methods for treatment of human skin. Such methods include those for regulating sebum on facial skin of a human subject, comprising applying to said...
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6086857 |
Cinnamylidene camphor derivatives and their use as UV-A protecting agents
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6057372 |
Antibacterial agents and cosmetics and clothing containing the same
Safe antibacterial agents containing macrocyclic lactones and/or macrocyclic ketones usable for suppressing the growth of indigenous dermal bacteria. Cosmetics containing these antibacterial agents...
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6051602 |
Methods for regulating skin appearance
The present invention relates to methods for prevention or treating skin disorders using flavonoid compounds. The present invention also relates to methods for regulating skin condition.
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5977184 |
Quercetin chalcone and methods related thereto
Quercetin chalcone, an effective, soluble and bioavailable bioflavonoid, is disclosed. Also disclosed are compositions containing quercetin chalcone in combination with an acceptable carrier and/or...
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5968482 |
α-hydroxyketoalkyl derivatives as light protection filters
The invention relates to the use of α-hydroxyketoalkyl derivatives as light protection filters for cosmetic or pharmaceutical products, the α-hydroxyketoalkyl group being linked, if appropriate...
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5955081 |
Antipsoriatic compositions, method of making, and method of using
A psoriasis treatment composition derived from the plant Asphodelus Microcarpus includes 3-methylanthralin, chrysophanol, aloe-emodin, aloe-emodin monoacetate, and/or derivatives thereof. The...
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5952391 |
Use of flavones and flavonoids against the UV-induced decomposition of dibenzoylmethane and its derivatives
Use of flavone derivatives and flavanone derivatives, in particular flavonoids for stabilizing cosmetic or dermatologically acceptable substances, the chemical formula of which includes the...
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5922775 |
Method of treating malignant tumors with ketone thyroxine analogues having no significant hormonal activity
The present invention provides methods for treating cancer, particularly malignant tumors, with ketone thyroxine analogues having no significant hormonal activity. A ketone thyroxine analogue is...
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5902831 |
Prevention of atherosclerosis using NADPH oxidase inhibitors
A method for the prevention and treatment of atherosclerosis and its related diseases in mammals, in which an NADPH oxidase inhibitor is administered, is provided. The NADPH oxidase inhibitor...
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5807898 |
Antimalarial agents
The invention describes a method of killing or inhibiting the growth of the malaria causing pathogen Plasmodium falciparum by exposing the pathogen to a preparation containing...
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5776439 |
Sun protecting cosmetic compositions comprising derivatives of dibenzoylmethane and of benzophenone
Cosmetic compositions containing sunscreens against sun radiation ranging from 280 to 380 nm, and their use for the protection of the skin from UV radiation. The sunscreens comprise, with respect...
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5760092 |
Allocolchinones and uses thereof
Disclosed are allocolchinones, which are anti-mitotic agents. Allocolchinones bind to tubulin reversibly and are more effective at inhibiting microtubule formation than colchicine....
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5679716 |
Pharmaceutical composition for treating osteoporosis
A therapeutic agent for osteoporosis comprising as an active ingredient xanthohumol. Xanthohumol obtained from hop extracts has a bone resorption inhibiting activity and is useful as a therapeutic...
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5624663 |
Photostable cosmetic filter composition cotaining a UV-A filter and a substituted dialkylbenzalmalonate, the use of substituted dialkylbenzalmalonates in cosmetics as broad-band solar filters and novel substituted dialkyl malonates
A photostable cosmetic filter composition for protecting human skin against UV radiation at wavelengths between 280 and 380 nm comprises, in a cosmetically acceptable support medium containing at...
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5605680 |
Photostable cosmetic composition containing a UV-A screen and a UV-B screen and a process for stabilizing the UV-A screen with the UV-B screen
The invention relates to a photostable screening cosmetic composition for protecting human skin against UV rays, comprising, in a cosmetically acceptable substrate containing at least one fatty...
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5587150 |
Photostable cosmetic screening composition containing a UV-A screening agent and an alkyl β, β-diphenylacrylate or α-cyano-β , β-diphenylacrylate
A photostable cosmetic screening composition and process for protection of the human epidermis against UV rays of wavelengths between 280 and 380 nm, the composition having, in a cosmetically...
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5545399 |
Cosmetic composition
A composition for topical application to the skin in order to promote the repair of photo-damaged or aged skin and/or to reduce or prevent damaging effects of ultra-violet light on skin and/or to...
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5446068 |
1-phenyl-3-phenyl-2-propyne-1-ones as calcium uptake inhibitors
This invention relates to 1-phenyl-3-phenyl-2-propyne-1-ones, the use of these compounds as calcium uptake inhibitors in leukocytes and thrombocytes, and pharmaceutical compositions containing...
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5430062 |
Stilbene derivatives as anticancer agents
The present invention relates to stilbene derivatives which possess utility as anti-cancer agents. The compounds can be used to treat cancers which are susceptible to treatment therewith, and can...
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5276058 |
3,4-dihydroxychalcone derivatives
Novel 3,4-dihydroxychalcone derivatives useful as a pharmaceutical material, and novel anti-inflammatory preparations. The 3,4-dihydroxychalcone derivatives are compounds of the formula [I],...
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5234951 |
Anti-ulcer agent comprising chalcone derivative
The present invention relates to an anti-ulcer agent comprising a compound represented by the following general formula I as the effective ingredient, and a novel chalcone derivative included in...
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5093372 |
Novel pharmaceutical composition comprising exifone and water-soluble polymer
A pharmaceutical composition which is a physical mixture of exifone and certain water soluble cellulose derivatives. The mixture exhibits surprisingly improved solubility and bio availability.
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5059627 |
Nerve growth factor secretion inducing composition
A compound of the formula: ##STR1## wherein R 1 is a lower alkyl group; R 2 is a hydrogen atom or an alkyl or alkenyl group which may be substituted; R 3 and R 4 each independently means a...
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5032580 |
Compositions for activirus medicines
Compositions for anti-AIDS virus and other antivirus medicines are disclosed. Included are one having the ingredients other than glycyrrhizin contained in licorice, specifically flavonoids...
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4952401 |
Rodenticide for toxic wick
A composition and a method of using the same wherein said composition comprises a rodenticide and an additive selected from the group consisting of 1. polyoxyalkylated alkyl phenols; 2....
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