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7488493 |
Performance aid for pesticide or repellent compositions
A performance aid for increasing the effectiveness of a bioactive agent, and a composition including both the performance and the bioactive agent. The performance aid increases the effectiveness of...
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7435757 |
2-substituted D-homo-estra-1,3,5(10)-trienes as inhibitors of 17β-hydroxy steroid dehydrogenase type 1
The invention relates to new 2-substituted D-homo-estra-1,3,5(10)-trienes of general formula I
in which
R 2 means a C 1 -C 8 -alkyl group, a C 1 -C 8 -alkyloxy group or a halogen atom,...
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7432303 |
Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states
The present invention relates to chalcone and chalcone derivatives and analogs which are useful as angiogenesis inhibitors. The present compounds, which are inexpensive to synthesize, exhibit...
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7432284 |
Estrogen receptor modulators
The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen...
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7157477 |
Aliphatic amino-substituted demethoxylated hypocrellins and their synthesis
The invention involves a methods and compositions for use in photodynamic therapy. Novel perylenequinone derivatives, conjugates comprising perylenequinone derivatives and a binding agent, and...
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7122518 |
Method for preventing or reducing collateral phototoxic damage to neighboring tissues during photodynamic therapy of a target tissue
A method is provided for preventing or reducing the adverse effects of photodynamic therapy such as collateral damage by regulating the localized phototoxicity of an effector photosensitizer...
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7101917 |
Mitochrondrial permeability transition pore affinity labels and modulators
Methods of utilizing compounds of general formulas I and II as modulators and affinity labels of the MPTP complex are elucidated. Furthermore, methods for modulating the activity of the MPTP...
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7087599 |
Estrogen receptor modulators
The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen...
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RE39199 |
Antipsoriatic compositions, method of making, and method of using
A psoriasis treatment composition derived from the plant Asphodelus Microcarpus includes 3-methylanthralin, chrysophanol, aloe-emodin, aloe-emodin monoacetate, and/or derivatives thereof. The...
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7060686 |
Anti-inflammatory compounds derived from Pseudopterogorgia elisabethae
Methods for treating, preventing, or inhibiting diseases and disorders associated with inflammation, cell-proliferation, and pain comprising the administration of a compound having the structural...
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6949557 |
Hydroanthracene based compounds as anticancer agents
The invention relates to the use of novel anthracene based compounds for the inhibition or prevention of the growth or multiplication of cancer cells, and to therapeutic compositions containing...
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6949250 |
Selective algaecides for control of cyanochloronta
We have now discovered that certain 9,10-anthraquinone derivatives we developed possess potent activity against O. perornata while possessing a sufficiently high level of solubility in water to...
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6936571 |
Fungicidal composition containing PQDs
The present invention provides an agricultural fungicidal composition containing active compounds selected from perylenequinonoid derivatives or salts thereof. The invention also relates the...
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6906059 |
Pharmaceutical composition with protective action against oxidative/toxic substances, especially cardiotoxic substances
The use of benzazepin-N-acetic acid derivatives which contain an oxo group in the a position to the nitrogen atom and are substituted in the 3 position by a...
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6894073 |
Use of diterpene compound as a therapeutic agent of inflammation, immune disease or cancer
The disclosure concerns novel use of diterpene compound as a therapeutic agent of inlfammation, immune disease or cancer. More particularly, the present invention relates to novel use of diterpene...
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6867235 |
Helianthrone derivatives as anti-cancer agents
Hypericin, helianthrone and derivatives thereof of general formula (I)
wherein the dotted line between positions 11 and 12 represent an optional C11-C12 bond; R is independently selected from...
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6812255 |
Use of aloe-emodin in the treatment of neuroectodermal tumors
The invention relates to the use of anti-cancer drug of a natural compound of vegetal origin, known as aloe-emodin (AE). Indeed, said compound has proved to have a specific biological activity of...
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6790463 |
Uses of targeted oxidative therapeutic formulation in arteriosclerosis
The use of a pharmaceutical formulation in treating coronary arteriosclerosis and a two-component pharmaceutical formulation. The pharmaceutical formulation contains peroxidic species or reaction...
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6777447 |
Derivatives of benzylidene cyclohexanone, benzylidene cyclopentanone, and benzylidene acetone, and therapeutic uses thereof
Benzylidene cyclohexanone, cyclopentanone and acteone derivatives and therapeutic methods of using same are disclosed. The compounds are non-toxic and exhibit potent anti-inflammatory,...
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6773727 |
Use of gossypol and related terpenes for control of urban and agricultural pests
Low concentrations of gossypol and related phyllophage toxins from cotton improve the effectiveness of insecticidal agents against social insects, including cockroaches, and particularly termites...
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6706767 |
Therapeutics for chemokine mediated diseases
The invention provides therapeutic and biological uses of chemokine-receptor-binding compounds including uses in the treatment of disease states mediated by chemokines. The relevant chemokines may...
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6706713 |
Conjugate for treating inflammatory infectious and/or skin diseases
This invention relates to the use of a conjugate comprising an active substance and a native protein which is not recognized as foreign protein for the production of a pharmaceutical preparation...
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6696484 |
Method and compositions for regulation of 5-alpha reductase activity
Pharmaceutical compositions and methods for treating androgen related disorders. The pharmaceutical compositions may include a 5α-reductase inhibitor, such as natural and synthetic flavanoids,...
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6686393 |
Pharmaceutical compositions having antiviral activity against human cytomegalovirus
The present invention is directed to the use of antiviral compounds having the following generalized structure: wherein R is 2H or ═O; R′ is OH, H, or COOH (single substitution); and R″ is...
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6627664 |
Perylenequinones for use as sonosensitizers
The invention is perylenequinones that are both sonosensitizers and photosensitizers, and their therapeutic use.
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6596774 |
Synthesis, lipid peroxidation and cytotoxic evaluation of 10-substituted 1,5-dichloro-9(10H)-anthracenone derivatives
The present invention is the synthesis of a series of 1,5-dichloro-9(10H)-anthracenones bearing O-linked and N-linked substituents in the 10-position. These compounds were evaluated for their...
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6586419 |
Phototherapeutic inactivation of ocular viruses
A method for inactivating ocular viral pathogens and for treating associated lesions on tissue by means of selectively activating a tissue-associated photosensitizing agent with light. The...
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6576660 |
Methods and compositions for regulation of 5-α-reductase activity
Compounds that inhibit 5-alpha-reductase are provided. The compounds are used to treat prostate cancer, breast cancer, obesity, skin disorders and baldness.
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6528489 |
Mycotoxin derivatives as antimitotic agents
The present invention provides a treatment for mammalian diseases characterized by aberrant cell proliferation. The treatment consists of administering therapeutically active dosages of antibiotic...
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6518316 |
Cytokine production and tyrosine kinase inhibitors
A compound of formula (I), wherein αX is ═O, ═N—OR 6 , βNHR or βOH wherein R 6 is H or C 1 -C 6 alkyl, bond a is oriented γ or δ and R is H, C 1 -C 6 alkyl which is unsubstituted or...
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6492332 |
Irrigation solution and methods for inhibition of tumor cell adhesion, pain and inflammation
This invention relates to a method of inhibiting tumor cell adhesion, pain, and inflammation at a wound during a surgical procedure by delivering an irrigation solution containing a tumor cell...
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6436423 |
Product and method for improving avian health
A product and method for reducing and preventing the ingestion of substrates by avians wherein the substrates are disposed within an avian house. The product is a bird repellent in combination with...
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6423323 |
Foam skin cream, uses of the foam skin protection cream and a process for its preparation
A foam skin cream can be obtained by preparing a phase I by melting at 75° C. a mixture containing fatty acids, especially C 12 -C 22 fatty acids, optionally unsaturated and/or polyunsaturated...
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6346282 |
Neuroprotective composition for the prevention and/or treatment of nervous and behavioural alterations due to anxiety states or depression, comprising acetyl-L-carnitine and hypericin
This invention relates to a composition of acetyl-L-carnitine in combination with hypericin and/or Hypericum extract ( Hypericum perforatum L . (St. John's Wort)) in synergistically effective...
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6328986 |
Method of deterring birds from plant and structural surfaces
A method for deterring birds from perching, roosting or loafing on plant and structural surfaces by applying to the surfaces a non-toxic composition. The non-toxic composition is one that triggers...
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6300376 |
Indane dimer compounds and their pharmaceutical use
Indane dimer compounds and their pharmaceutical use particularly to achieve smooth muscle relaxing activity and/or mast cell stabilizing activity and/or anti-inflammatory activity are described.
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6258856 |
Method for preventing or controlling cataract
A method for preventing or treating pathological changes which occur in association with cataract formation in the mammalian eye by protecting lens cells against the cataractogenic effects of...
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RE37087 |
Insecticidal triffluormethyl alkane derivatives
There are provided new alkane and alkoxyalkane derivatives of the general formula I ##STR1## in which R 1 , R 2 , R 3 , R 4 and A have the meanings given in the description, processes for their...
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6150414 |
Compositions and methods for treating viral infections
Disclosed herein are antiviral agents, pharmaceutical formulations comprising effective amounts of these agents and methods for treating mammals suffering from infections caused by viruses. The...
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6127426 |
10-substituted 1,8-dihydroxy-9 (10H) anthracenone pharmaceuticals
Therapeutic compositions comprising 1,8-dihyroxy-9(10H) anthracenones substituted at position 10 thereof with phenylalkylidene or arylacyl blacking moieties, said compounds having substantial...
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6107346 |
Methods for treating hyperlipidemia
The present application relates to a series of compounds, and pharmaceutical formulations thereof, of the formula ##STR1## which provide a method of inhibiting hyperlipidemia, especially...
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6090369 |
Sunscreen formulation with avobenzone and method for stabilizing sunscreen formulation which contains avobenzone
The invention relates to a photostable screening cosmetic composition for protecting human skin against UV rays, comprising, comprising avobenzone, octyl-methoxycinnamate, and an additional...
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6086857 |
Cinnamylidene camphor derivatives and their use as UV-A protecting agents
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6080791 |
Method of treating a viral condition by inhibiting membrane fusion
A method of preventing and treating a viral condition caused by an enveloped virus is described, comprising using a therapeutically effective amount of a compound selected from the group consisting...
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6080739 |
Colchicine-skeleton compounds, their use as medicaments and compositions containing them
The present invention relates to colchicine and thiocolchicine derivatives which can be obtained from these molecules by functionalization of the C-7 to ketone or functionalization of the amino...
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6057372 |
Antibacterial agents and cosmetics and clothing containing the same
Safe antibacterial agents containing macrocyclic lactones and/or macrocyclic ketones usable for suppressing the growth of indigenous dermal bacteria. Cosmetics containing these antibacterial agents...
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6001882 |
Photoactivated hypericin and the use thereof
The invention provides methods of using photoactivated hypericin compounds which, when photoactivated using visible or UV-A light, are useful for treating numerous diseases and disorders in...
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5972987 |
Method for removing nits from hair
A method for removing lice eggs from the hair of an infested human or animal using a nit-visualizing composition. The composition involves the use of certain dyes which have an affinity to the...
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5945449 |
Sterile bicarbonate concentrate
A sterile bicarbonate concentrate for use in the present invention relates to a sterile calcium-free bicarbonate concentrate for use in peritoneal dialysis, hemofiltration, cardiac bypass surgery...
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5922774 |
Method for controlling plant damage by insect herbivores
Method for repelling insect herbivores from plant surfaces and deterring them from feeding on plant surfaces by applying an aqueous dispersion of polycyclic quinone or precursor thereof to the...
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