Matches 51 - 100 out of 120 < 1 2 3 >
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5904923 Methods for preparing pharmaceutical compositions and using same to treat drug addiction  
The invention discloses to methods for preparing and using a lipophilic extract of the roots of Salvia miltiorrhyza Bunge for treating drug addiction. The Tanshinone IIA and Miltirone components of...
5885604 Method for protecting seeds from birds  
A method for deterring birds from damaging planted seeds by applying to the seeds before planting or to the surface of the ground overlying the planted seeds a non-toxic solid coating material...
5837255 Method of reducing blood glucose by administering Harunganin or Vismin  
The use of extracts from Harungana or Vismia spp. or anthracenone compounds harunganin and vismin contained therein or isolated therefrom as hypoglycemic agents, as well as methods for obtaining...
5834521 Substituted dibenz (A F)azulenes and methods of preparation  
Tetracyclic compounds having the following structure are described: ##STR1## wherein R 1 -R 10 are as defined. The tetracyclic compounds are capable of potent effects on steroid sensitive tissues...
5760092 Allocolchinones and uses thereof  
Disclosed are allocolchinones, which are anti-mitotic agents. Allocolchinones bind to tubulin reversibly and are more effective at inhibiting microtubule formation than colchicine....
5716994 Antitumor and antileukaemic substances, their preparation and pharmaceutical compositions containing them  
(3-hydroxy-4-methoxybenzyl)-7-methylene-1-vinyl-2,3,3a,4,7,7 a-hexahydroinde n-4-one of formula (I): ##STR1## and 3-(3-hydroxy-4-methoxybenzyl)-4-hydroxy-7-methyl-1-vinylinda n of formula (II):...
5705169 Ketotricyclo .5.2.1.0! decane derivatives  
The invention relates to ketotricyclo 5.2.1.0!decane derivatives of the formula I ##STR1## wherein Phe is a phenylene group which is unsubstituted or substituted by 1 to 4 hydroxyl, alkyl or alkoxy...
5705533 10-thio-substituted 1,8-dihydroxy-9 (10H) -anthracenone pharmaceuticals  
10-thio-substituted 1,8-dihydroxy-9(10H) anthracenones, therapeutic compositions containing at least one of the 10-thio-substituted 1,8-dihydroxy-9(10H) anthracenones of the invention and methods...
5674900 Terpenoid-type quinones for treatment of diabetes  
Novel terpenoid-type quinones which can be obtained from Pycnanthus spp., processes for obtaining the novel terpenoid-type quinones and methods for their use as hypoglycemic agents, for example, in...
5663180 Substituted cyclopentenes for the treatment of inflammation  
A class of 1,2-diarylcyclopentenyl compounds is described for use in treating inflammation and inflammation-related disorders. Compounds of particular interest are defined by Formula III: ##STR1##...
5578646 Pharmaceutically acceptable anthracene compounds  
The invention concerns the use of bis-anthracene compounds isolated from Karwinskia humboldtiana in therapy. The compounds of the invention are selective with a high margin of safety relative to...
5519027 D-homo-(16-ene)-11β-aryl-4-estrenes, process for their production as well as their use as pharmaceutical agents  
New D-homo-(16-ene)-11β-aryl-4-estrenes of general formula I ##STR1## as well as their pharmaceutically compatible addition salts with acids are described in which X stands for an oxygen atom,...
5514714 Methods and polycyclic aromatic compound containing compositions for treating T-cell-mediated diseases  
T cell-mediated diseases in mammals are treated using compositions comprising a polycyclic aromatic compound, preferably hypericin or pseudohypericin, and related compounds, including isomers,...
5501855 Neem oil as a male contraceptive  
An alternate approach to vasectomy for long term male contraception following a single intra-vas.application of a traditional plant (Azadirachta indica) product having immunomodulatory properties...
5492917 Endothelin antagonists incorporating a cyclobutane  
Novel compounds of the general structural formula I: ##STR1## have endothelin antagonist activity and are therefore useful in treating cardiovascular disorders, such as hypertension, pulmonary...
5492690 Benzoylacetate esters as non-sensitizing chelating photo-protectants  
The subject invention relates to pharmaceutical compositions comprising a safe and effective amount of a compound having the structure: ##STR1## wherein n is 3 or 4; each R is independently alkyl...
5480913 Anti-androgen compounds  
Disclosed are novel classes of anti-androgens including dihydrophenanthrene derivatives, their method of synthesis and their use in treating disorders associated with excessive androgenic activities.
5478862 15,16-seco-19-nor progestins  
The invention is drawn to 17-oxo-15,16-seco-19-nor steroids which are useful as intermediates in the production of various 15,16-seco-19-nor progestins. These progestins display elevated...
5457108 5-oxo-dibenzo[a,d]cyclohepta-1,4-dienes  
The invention relates to substituted 5-oxo-di-benzo[a,d]cyclohepta-1,4-dienes of the formula (I) ##STR1## processes for their preparation and their use as retroviral agents.
5409959 Antithrombotic treatment with calix(n)arene compounds  
A method of inhibiting thrombus formation in a mammalian subject. The method involves administering to the subject a therapeutically effective dose of a calix(n)arene compound derivatized, at its...
5393785 Therapeutic antiestrogens  
Novel antiestrogenic compounds are disclosed for use in therapeutic preparations for treatment of estrogen-dependent diseases. The compounds are specified diphenylethane and diphenylethylene...
5380755 Alkyl and alkylbenzyl ethers of substituted hydroquinones  
The present invention provides alkyl and alkylbenzyl ethers of substituted hydroquinones and pharmaceutical compositions containing them. The present invention further provides methods of using...
5187195 Anthraquinone derivatives and preparation thereof  
Anthraquinone compounds of the formula: ##STR1## wherein: R 1 is hydrogen, hydroxy or acyloxy, R 2 is hydrogen or acyl, R 3 is acyl, R 4 is hydrogen or acyl, R 5 is hydrogen or...
5158775 Aerosols of pyrido [1,2-a]pyrimidine compounds  
A suspension type aerosol inhalations containing (a) 0.015 to 5.00% (w/w) of a pyrido[1,2-a]pyrimidine compound of the formula: ##STR1## where R is a n-propyl or allyl group, A is a tetrazolyl or...
5141957 1,4-bis-(amino-hydroxyalkylamino)-anthraquinones for inhibiting protein kinase C  
The present invention provides novel substituted anthraquinones having the formula ##STR1## wherein R 1 and R 2 are independently H, alkyl, aryl, or arylalkyl; m and n are independently 1, 2,...
5140044 UCN-1028D derivatives  
A UCN-1028D derivative represented by the formula: ##STR1## has protein kinase C inhibitory activity and is expected to be used as an active ingredient in anti-tumor agents, etc.
5100921 Angucyclinones from Streptomycetes, a process for the preparation thereof, and the use thereof  
New angucyclinones with a therapeutic action can be prepared with the aid of a strain of the genus Streptomyces.
5079376 Novel substance UCT-1003 and process for producing the same  
Disclosed is novel compound UCT-1003 represented by the following formula: ##STR1## and having anti-tumor activity. UCT-1003 is produced by culturing a microorganism belonging to the genus...
5075339 Benzylketone phospholipase A.sub.2 inhibitors  
The invention relates to benzylketone phospholipase A 2 inhibitors, pharmaceutical compositions containing them, and methods of treating phospholipase A 2 -mediated conditions in mammals by...
5039707 1,3,6,8 tetrahydroxyanthraquinone  
A method for causing laxation using 1, 3, 6, 8-tetrahydroxyanthraquinone.
5034420 Compositions and method for stabilization of anthralin comprising the addition of an oil soluble antioxidant and an anionic surfactant  
This invention relates to an anthralin composition having improved stability. The invention further relates to a method for increasing the stability of anthralin in dermatological compositions by...
4962125 Novel substance KS-619-1, preparation process and pharmaceutical composition  
A novel physiologically active substance KS-619-1 having a vasodilative activity is produced by culturing Streptomyces californicus ATCC 3312.
4883822 Agent for regulating the motional function of gastrointestinal tract  
An agent for regulating the motional function of the gastrointestinal tract, which contains as an active ingredient a 41-metyl-4,4a,9,10-tetrahydro-2(3H)-phenanthrenone derivative represented by...
4859697 Substituted acenaphthenes and their use as inhibitors of phospholipase A2  
Substituted acenaphthenes and their use as inhibitors of phospholipase A 2 are provided. The acenaphthenes have the formula ##STR1## wherein R 1 is H or alkyl; R 2 is alkyl, cycloalkyl, or...
4843097 10-aryl-1,8-dihydroxy-9-anthrones and their esters, process for preparing same, and use of same in human and veterinary medicine and in cosmetics  
Mono, di and tri-esters of 1,8-dihydroxy-10-phenyl-9-anthrone or -9-anthranol have the formula ##STR1## wherein p is 0 or 1, (a) when p=0, t=1 and R 2 represents hydrogen or --COR 3 , (b)...
4837213 Pharmaceutical vehicle for active substances in the form of an anhydrous gel  
A pharmaceutical vehicle used for administering and protecting active substances, in the form of an anhydrous gel and having a viscosity of at least 540 cps, comprising paraffin oil, at least one...
4826677 Pharmaceutical material for the treatment of psoriasis  
The invention relates to pharmaceutical materials for local and non-irritating therapy for psoriasis, containing antipsoriatic ingredients. The pharmaceutical material is a liquid preparation of...
4820738 1,4-bis(substituted-amino)-5,8-dihydroxy-anthraquinones and leuco bases thereof  
This disclosure describes symmetrical 1,4-bis(substituted-amino)-5,8-dihydroxyanthraquinones useful as chelating agents and for inducing regression and/or palliation of cancer diseases in mammals.
4808625 Phenanthrene derivatives  
The present invention relates to compounds of formula (I) ArCH 2 R 1 (I) or a monoethyl ether thereof (the compound of formula (I) including these ethers...
4699929 Pharmaceutical compositions for the treatment of skin  
Pharmaceutical compositions for the treatment of skin have been prepared in a carrier which contains 40 to 60% of liquid paraffin, 40 to 60% of solid paraffin, and 0.5 to 5% of microcrystalline...
4696941 1,8-diacyloxy-10-acylanthrones  
Compounds of the formula ##STR1## wherein R 1 and R 2 are the same or different and represent a straight-chain or branched alkyl group of 1 to 15 carbon atoms, a cycloalkyl group of 3 to 6 carbon...
4677123 Pharmaceutical and cosmetic compositions containing as an active ingredient 1,8-dihydroxy-10-phenyl-9-anthrone and a process for preparation thereof  
Pharmaceutical or cosmetic composition containing as the active component 1,8-dihydroxy-10-phenyl-9-anthrone, and a process for preparing said active component.
4670265 Aloe emodin and other anthraquinones and anthraquinone-like compounds from plants virucidal against herpes simplex viruses  
A method has been disclosed for treating type 1 or 2 herpes simplex virus comprising the successive steps of: (1) topically applying to the virus-affected areas of a person suffering from said...
4656192 Tropolone derivatives, processes for the preparation thereof and the use thereof as anti-tumor agents  
New tropolone derivatives of the general formula: ##STR1## wherein R 1 represents H or an alkyl group, R 2 represents an alkyl, aryl, aralkyl or heterocyclic group and R 3 represents an alkoxyl,...
4610986 Aminonaphthacene derivatives and their production  
A (7S,9S) isomer or its racemic modification of the aminonaphthacene derivative of the formula: ##STR1## wherein R 1 is a hydrogen atom, a hydroxyl group or a lower alkoxy group, R 2 is a...
4607054 Antiandrogenic compositions containing indene-7-ones  
Novel antiandrogenic compositions comprising an antiandrogenically effective amount of at least one compound of the formula ##STR1## wherein R is alkyl of 1 to 4 carbon atoms, R 1 is alkyl of 1 to...
4602004 Aloin and aloe-emodin containing pesticides  
Invertebrate pests including arthropods, annelids, and vermids are substantially completely killed upon contact with a compound selected from the class consisting of ##STR1## Both members of the...
4581377 Fluorene derivatives  
Compounds of formula I below are useful as anti-inflammatory, analgesic and/or anti-pyretic agents: ##STR1## in which R 1 is hydrogen, nitro, amino, hydroxyl, alkoxy of one to four carbon atoms,...
4576964 Substituted hexahydrobenzo[e]indene and octahydrophenanthrene CNS agents and pharmaceutical compositions thereof  
Tricyclic benzo fused compounds of the formula ##STR1## and pharmaceutically acceptable cationic and acid addition salts thereof, wherein n is zero, 1 or 2, and t is 1 or 2; M is CH or N, R 1 is H...
4569944 Dibenzosuberone as a non-steroidal anti-inflammatory compound and compositions thereof  
A non-steroidal anti-inflammatory composition comprising an active anti-inflammatory agent having the formula: ##STR1## The active agent is formulated with a pharmaceutically acceptable carrier for...
Matches 51 - 100 out of 120 < 1 2 3 >