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7605179 |
Napthoquinone derivatives as inhibitors of tau aggregation for the treatment of alzheimer's and related neurodegenerative disorders
Provided are napthoquinone-type compounds which can be used to modulate the aggregation of protein (e.g. tau) associated with neurodegenerative disease (e.g. Alzheimer's disease)....
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7586008 |
Propofol analogs, process for their preparation, and methods of use
The invention provides para substituted dialkylphenol derivatives of propofol. The invention further provides pharmaceutical compositions comprising such analogs, methods for preparing such...
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7531188 |
Pest-combating compositions comprising soy methyl ester
A pest-combating composition including soy methyl ester, and methods of combating pests utilizing same. Such composition in a preferred formulation may also include 2-undecanone. The composition...
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7485666 |
Vaginal health products
The invention provides compositions and methods for increasing cell growth, stimulating cell turnover and promoting the secretion of mucus within the reproductive tract of a female mammal.
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7485743 |
Oligomeric ketone compounds
A novel keto8enic compound is provided having general: Formula R(OCH(CH 3 )CH 2 C(O)) n —O-A wherein n is an integer of 3 to 10, A is the residue of a 3-keto alkan-1-ol and R is selected from the...
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7432284 |
Estrogen receptor modulators
The present invention relates to compounds and derivatives thereof, their synthesis, and their use as estrogen receptor modulators. The compounds of the instant invention are ligands for estrogen...
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7423068 |
Control of parasitic mites of honey bees
The present invention is directed to methods and compositions for use to control parasitic mites of honey bees, particularly Varroa mites. In one aspect, the invention is directed to control of...
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7410656 |
Anti-cancer compounds
This invention relates to a compound or group of compounds present in an active principle derived from plants of species Euphorbia peplus, Euphorbia hirta and Euphorbia drummondii , and to...
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7345096 |
Use of norepinephrine reuptake modulators for preventing and treating vasomotor symptoms
The present invention relates to the use of compounds and composition of compounds that modulate norepinephrine levels for the prevention and treatment of vasomotor symptoms, such as hot flush,...
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7304093 |
Ketone compounds and compositions for cholesterol management and related uses
The present invention relates to novel ketone compounds, compositions comprising ketone compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias,...
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7282491 |
Prokaryotic proteasomal proteases of Mycobacterium tuberculosis (MTB) as targets for antibiotic therapy
The present invention relates to methods of treating Mycobacterium pathogen infection in a subject that involve: inhibiting proteasomal activity in a pathogen under conditions effective to make...
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7259187 |
Tropolone derivatives
Tropolone derivatives represented by the formula (I), which have retinoid actions and are useful as active ingredients of medicaments [R 1 to R 4 represent hydrogen atom, an alkyl group, or an...
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7202279 |
Cyclic dipeptides and azetidinone compounds and their use in treating CNS injury and neurodegenerative disorders
The present invention provides 4-substituted-2-azetidinone compounds, bicyclic 2-5-diketopiperazine compounds, and pharmaceutical compositions thereof that are potent, safe and effective...
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7196065 |
Enteral formulation
A formulation for enteral administration to a patient is disclosed.
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7192601 |
Antimicrobial and sporicidal composition
Germicidal compositions with enhanced activity towards killing microbiological spores and vetgetative cells comprising certain quaternary ammonium compounds (QACs), phenolic compounds, monohydric...
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7186756 |
Steroid derivatives and use thereof as medicaments
Steroids of the formula
wherein R is defined as in the application capable of increasing the synthesis of collagen.
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7179480 |
Sustained release microcapsules
A sustained release microcapsule comprises (a) an interfacially-polymerized polymer shell comprising at least one shell stabilizer; and (b) a fill composition comprising (1) at least one...
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7132458 |
Oxidized carotenoid fractions and ketoaldehyde useful as cell-differentiation inducers, cytostatic agents, and anti-tumor agents
This invention features fractionated oxidized carotenoid or retinoid mixtures, and individual components thereof, which are useful as cell-differentiation-inducing, anti-proliferative,...
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7053119 |
Methods for identifying and using IKK inhibitors
The present invention provides methods and compositions for inhibiting IKK, as well as methods and compositions for identifying compounds with activity as inhibitors of IKK, and methods and...
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7012071 |
Compounds for the treatment of metabolic disorders
Compounds useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and...
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6984389 |
Using heat shock proteins to improve the therapeutic benefit of a non-vaccine treatment modality
The present invention relates to methods of improving a treatment outcome comprising administering a heat shock protein (HSP) preparation or an α-2-macroglobulin (α2M) preparation with a...
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6958360 |
Attractant pheromone for the Colorado potato beetle
A method has been discovered for attracting Colorado potato beetles to an area of object or area, which method involves treating the object or area with a Colorado potato beetle attracting...
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6946492 |
Use of C2-substituted indan-1-one systems for preparing medicaments for the treatment of obesity
Embodiments of the invention relate to methods of reducing weight in mammals and for the prophylaxis or treatment of obesity comprising administration of C2-substituted indan-1-one systems and...
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6919299 |
Synergistic herbicidal compositions
Herbicidal compositions comprising
A) 2-[2-chloro-3-(2,2,2-trifluoroethoxymethyl)-4-methylsulfonyl
-benzoyl]cyclohexane-1,3-dione and B) at least one compound from the group consisting of...
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6906106 |
Compositions for the skin comprising fibers and ubiquinones and methods of using the same
The present invention relates to a composition for topical application on the skin, comprising fibers and at least one or two or more compounds selected from the group of the ubiquinones and...
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6849276 |
Liquid composition with fungicide, bactericidal and bacteriostatic activity
The invention concerns a phytosanitary fungicide, bactericidal or bacteriostatic composition comprising at least a mineral salt, a copper oxide or hydroxide suspended in an aqueous emulsion of at...
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6846845 |
Heat shock protein inducer
A heat shock protein inducer is provided for purposes of preventing or treating ischemic disease or ischemia/reperfusion injury. This heat shock protein inducer has geranylgeranylacetone as an...
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6844013 |
Methods of stimulating the immune system
This invention relates to a compound or group of compounds present in an active principle derived from plants of species Euphorbia peplus, Euphorbia hirta and Euphorbia drummondii , and to...
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6827941 |
Use of carotenoid aggregates as colorants
Carotenoid aggregates are useful as colorants for foods and for cosmetic and pharmaceutical preparations.
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6825183 |
Substituted benzoylcyclohexanediones for use as herbicides
The invention relates to novel substituted benzoylcyclohexanediones of the general formula (I) in which A 1 represents a single bond or represents alkanediyl (alkylene) having 1 to 3 carbon...
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6811789 |
Fragrant composition having mosquito-repelling effect
A mosquito-repelling agent which is gentle to human and environment and safe, and has an excellent mosquito-repelling effect almost equal to the effect of DEET and also an excellent persistency of...
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6811791 |
Method and concentrated composition for insect and animal control
Insect and animal control water based concentrate and and dilute compositions and method in which a polymer and solubilizer are selected to provide a cross-linked film with matrices of sufficient...
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6803385 |
Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders
Hydroxyeicosatetraenoic acid esters and methods of their use in treating dry eye disorders are disclosed.
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6803367 |
Substance for inducing apoptosis
A substance for inducing apoptosis represented by specific formulae. A pharmaceutical composition which can be used for an anticancer agent containing said substance.
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6800662 |
Method of repelling insects
A method of repelling an insect pest such as a tick, mosquito or cockroach comprises applying to a subject or substrate, in an amount effect to repel the insect pest, a compound of Formula I: ...
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6800279 |
Chemical composition that attract arthropods
Compositions and methods employing the compositions for attracting arthropods. The compositions comprise at least one compound of formula I and at least one compound from group II.
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6790463 |
Uses of targeted oxidative therapeutic formulation in arteriosclerosis
The use of a pharmaceutical formulation in treating coronary arteriosclerosis and a two-component pharmaceutical formulation. The pharmaceutical formulation contains peroxidic species or reaction...
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6756045 |
Topically applied idebenone-containing agent with protective and regenerative effect
A regenerative or protective topical skin preparation includes idebenone (6-(10-hydroxydecyl)-2,3-dimethoxy-5-methyl-1,4-benzochinol)
or a derivative of idebenone.
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6749862 |
Method and composition of disrupting feeding patterns of woodpeckers
A method and composition for deterring wood damage, such as caused by woodpeckers. The method includes blending Isophorone with an epoxy resin and acrylic based sealant to form a resin composition...
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6737041 |
Non-ozone depleting vapocoolants
Chemical compositions are provided, for use as topical anesthetics or skin refrigerants. These compositions do not cause the depletion of the stratospheric ozone layer and are non-toxic,...
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6676955 |
Method and composition for insect and animal control
Insect and animal control compositions and method in which a polymer and solvent are selected to provide a cross-linked film with matrices of sufficient capacity for trapping and being plated by an...
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6660288 |
Insect repellents
The use of specific perfume ingredients, e.g. tricyclodecenyl allyl ether, to repel insects. The perfume ingredients may be used in a composition comprising from 0.1 to 40 percent by weight of one...
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6649654 |
Methods for identifying and using IKK inhibitors
The present invention provides methods and compositions for inhibiting IKK, as well as methods and compositions for identifying compounds with activity as inhibitors of IKK, and methods and...
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6630130 |
Sunless tanning cream
A sunless tanning formulation is provided to impart a cosmetic coloring effect to skin. The formulation is particularly useful to camouflage the effects of vitiligo. The formulation has both makeup...
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6610748 |
Preventives/remedies for skin aging
A composition for prophylaxis and therapy of dermal aging which comprises a substance having human leukocyte elastase inhibitory activity as an active ingredient.
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6605641 |
20-HETE antagonists and agonists
20-HETE agonists and antagonists are disclosed along with therapeutic applications. In a preferable form of the invention, the 20-HETE agonists are selected from the group consisting of...
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6596755 |
Oral formulation of methylglyoxal and its imino acid conjugates for human use
The invention relates to an oral formulation of methylglyoxal and/or its imino acid conjugates for human use and methods for preparing the compositions. Particularly, the invention relates to...
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6576673 |
Method of deterring woodpeckers
A method of making a coating for deterring woodpeckers from damaging wood using Isophorone and the composition made therefrom. The Isophorone is combined with heated wax and combined with a...
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6552084 |
Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders
Hydroxyeicosatetraenoic acid analogs and methods of their use in treating dry eye disorders are disclosed.
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6540988 |
Method of reducing or preventing malodour
A method of reducing or preventing body malodour by topically applying to human skin perfume components capable of inhibiting the producation of odoriferous steroids by microorganisms on the skin....
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