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9023417 Use of a polyamine-poor composition for the production of a medical human food  
The disclosure relates to a novel use of a food composition for human use, having fewer than 1600 picomoles of polyamines, for the production of a medical food which is intended to combat a...
8741807 Plant activator  
A compound useful as a plant activator for activating an endogenous defense system of a plant to control disease damage is provided. A compound represented by the formula:...
8729033 Therapeutic, dietary or cosmetic use of compounds with specific anti-apoptotic activity toward caspase-3, and compositions containing these compounds  
This invention regards the use of zeaxanthin and/or rutin, as such or further combined with spermidine, as the active principle in a pharmaceutical, dietary, or cosmetic composition, acting to...
8603499 Cancer cell targeting using nanoparticles  
The present invention generally relates to polymers and macromolecules, in particular, to polymers useful in particles such as nanoparticles. One aspect of the invention is directed to a method of...
8603500 Cancer cell targeting using nanoparticles  
The present invention generally relates to polymers and macromolecules, in particular, to polymers useful in particles such as nanoparticles. One aspect of the invention is directed to a method of...
8603501 Cancer cell targeting using nanoparticles  
The present invention generally relates to polymers and macromolecules, in particular, to polymers useful in particles such as nanoparticles. One aspect of the invention is directed to a method of...
8273363 Cancer cell targeting using nanoparticles  
The present invention generally relates to polymers and macromolecules, in particular, to polymers useful in particles such as nanoparticles. One aspect of the invention is directed to a method of...
8246968 Cancer cell targeting using nanoparticles  
The present invention generally relates to polymers and macromolecules, in particular, to polymers useful in particles such as nanoparticles. One aspect of the invention is directed to a method of...
8236330 Cancer cell targeting using nanoparticles  
The present invention generally relates to polymers and macromolecules, in particular, to polymers useful in particles such as nanoparticles. One aspect of the invention is directed to a method of...
8198334 Methods for modulating macrophage proliferation in ocular disease using polyamine analogs  
Methods for modulating macrophage proliferation in an individual afflicted with or at risk for an ocular disease such as ARMD are provided. The methods employ a polyamine analog, or salt or...
8106080 Compositions and methods for enhancing nitric oxide delivery  
The present invention is directed to compounds, combinations, compositions and methods for enhancing nitric oxide (NO) delivery to target sites, and in particular to muscle, both normal and...
7928094 Treatment of diabetes with copper binding compounds  
Novel methods of treating a patient for diseases, disorders, and conditions including diabetes mellitus, comprising administering, for example, copper binding compounds.
7879914 Methods for treating viral infections using polyamine analogs  
Methods for treating viral infections using polyamine analogs, including mitoguazone (MGBG), are provided. In these methods, polyamine analogs destroy macrophages that act as viral reservoirs,...
7754765 Copper chelators for treating ocular inflammation  
In various aspects, the invention provides methods for treating ocular inflammation using copper chelating compounds, such as compounds other than D-penicillamine. In some embodiments, such...
7459446 Treatment of diabetes with copper binding compounds  
Novel methods of treating a patient for diseases, disorders, and conditions including diabetes mellitus, comprising administering, for example, copper binding compounds.
7279502 Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases  
Peptide conjugates in which cytocidal and cytostatic agents, such as polyamine analogs or naphthoquinones, are conjugated to a polypeptide recognized and cleaved by enzymes such as...
7273888 Use of difluoromethylornithine (DFMO) for the treatment of amyotrophic lateral sclerosis  
The present invention provides methods and compositions for modulating polyamine pathway activity as a means for ameliorating neurodegenarative disorders. In particular, for ameliorating the...
7232846 Amines as anti-alcoholism agents  
The oral administration to genetically alcoholic rats (from the strain UChB of the University of Chile) of a compound selected from endogenic polyamines (putrescine, spermidine, spermine),...
7202280 Methods for the treatment and prevention of pancreatitis and for induction of liver regeneration  
Novel methods for treating and preventing acute and/or chronic pancreatitis are described. Additionally, novel methods for inducing liver regeneration are described. The methods may comprise...
7094808 Analogs of biologically active, naturally occurring polyamines, pharmaceutical compositions and methods of treatment  
Polyamines having the formula: or a salt thereof with a pharmaceutically acceptable acid wherein: R1-R6 may be the same or different and are alkyl, aryl, aryl alkyl, cycloalkyl, optionally having...
7087648 Methods for modulating macrophage proliferation using polyamine analogs  
Methods for modulating macrophage proliferation in an individual afflicted with or at risk for a macrophage-associated disease are provided. The methods employ a polyamine analog, or salt or...
7045550 Polyamines and analogs for protecting cells during cancer chemotherapy and radiotherapy  
Polyamine effectors are administered locally to provide protection against the adverse side-effects of chemotherapy or radiation therapy, such as alopecia, mucositis and dermatitis. Pharmaceutical...
7008531 Treatment of circulating water systems  
The present invention relates to a method of inhibiting the growth of killing algae, bacteria, yeast and/or fungi in a recirculating water system which comprises adding to the water a polymeric...
6897243 Fructosamine oxidase: antagonists and inhibitors  
The present invention relates to methods of treating an individual with diabetes mellitus by administering to said individual an effective amount of copper chelators, hydrazine compounds, and/or...
6867237 DNA encoding apoptosis-induced eucaryotic initiation factor-5A and deoxyhypusine synthase and a method for controlling apoptosis in animals and humans  
Genes encoding an apoptosis-induced eukaryotic initiation Factor-5A (eIF-5A) and an apoptosis-induced deoxyhypusine synthase (DHS), whose expressions are induced by the onset of apoptosis, are...
6849648 Phenylene alkyne matrix metalloproteinase inhibitors  
A compound of Formula I or a pharmaceutically acceptable salt thereof, or a tautomer thereof, wherein G1, G2, and B are as defined in the application, are selective inhibitors of MMP-13. The...
6649587 Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases  
Peptide conjugates in which cytocidal and cytostatic agents, such as polyamine analogs or naphthoquinones, are conjugated to a polypeptide recognized and cleaved by enzymes such as...
6586478 Methods and compositions for improving sleep  
Methods and compositions for improving sleep in individuals with sleep disorders or other conditions which interfere with normal sleep via administration of a NO-mimetic are provided.
6576672 Polyamine treatment of neurological disorders  
2,3,2 Tetramine (3,7-diazanonane-1,9-diamine) is propounded for treatment of Parkingson's Disease and dementias characterized by mitochondrial damage in view of this compound's ability to...
6531512 Method of treating cancer in patients having a deficiency in p53 tumor suppressor gene  
A method of treating cancer in a patient deficient in p53 tumor suppression gene is described herein by administering to a patient a therapeutically effective amount if a polyamine such as DENSPM...
6482833 Immunotherapeutic anti-cancer pharmaceutical compositions  
There is disclosed a class of pharmaceutical compositions useful for the treatment of cancer, particularly solid tumors, and having a mechanism of action as spermine antagonists. The present...
6464764 Protective agents for wood  
Solvent-free coating materials and treating agents used as water-based wood or material protective agents containing emulsifiable binding agents, quaternary ammonium compounds and optional...
6444230 Synergistic composition of peracetic acid and amine oxide  
Composition in the form of an aqueous solution, useful for disinfecting hard surfaces comprises: a) from 0.0005% to 20% by weight of peracetic acid,b) from 0.001% to 45% by weight of acetic...
6399662 Method and composition for the treatment of diarrhea and gastrointestinal spasms  
Anti-diarrheal and/or gastrointestinal anti-spasmodic pharmaceutical compositions containing [A] a polyamine of the formula: R1—N1(R2)—(CH2)x—N2H—Q—N3H—(CH2)y—N4(R3)—R4 (I)wherein: R1, R2, R3 and...
6362232 Anti-neoplastic, anti-viral or anti-retroviral spermine derivatives  
The present invention relates to anti-neoplastic and anti-psoriasis pharmaceutical compositions and methods of treatment and to insecticidal compositions and methods of controlling the growth of...
6274630 Method of inhibiting biosynthesis of EIf5A  
A method and pharmaceutical composition for inhibiting or preventing the intracellular biosynthesis of EIf5A by the administration to a human or non-human mammal in need thereof an amount of a...
6235794 Biologically active spermidine analogues, pharmaceutical compositions and methods of treatment  
Polyamines having the formula: ##STR1##or a salt thereof with a pharmaceutically acceptable acid wherein: R1 -R5 may be the same or different and are alkyl, aryl, aryl alkyl, cycloalkyl or...
6217914 Ascorbic acid composition and method for treatment of aging or damaged skin  
An ascorbic acid-based composition and related method for the treatment of aging or photo-damaged skin is disclosed. The composition includes water and ascorbic acid, at least a portion of which...
6184254 Methods of identifying modulators of perivascular sensory nerve Ca2+ receptors  
Methods of identifying compounds that relax or stimulate arterial tension through their action on perivascular sensory nerve calcium receptors are described. Compounds identified through such...
6168808 Synergistic composition of peracetic acid and amine oxide  
Composition in the form of an aqueous solution, useful for disinfecting hard surfaces comprises: a) from 0.0005% to 20% by weight of peracetic acid, b) from 0.001% to 45% by weight of acetic acid,...
6160022 Chemical resection of pancreas  
A method of chemically resecting the exocrine portion of the pancreas of a patient in need thereof comprising administering to the patient an amount of a hydroxy polyamine or a salt thereof with a...
6015828 Chemical modification of chloride channels as a treatment for cystic fibrosis and other diseases  
This invention relates generally to medical treatment methods. Specifically, the invention relates to methodology for the correction of defective chloride transport by activation of chloride...
6011066 Method for treating septic shock  
A method for the treating septic shock in a patient comprises administering to the patient a therapeutically-effective amount of a composition comprising a compound having the formula (I):...
5962533 Hydroxy polyamines  
Disclosed are polyamines having the formula: ##STR1## or salts or stereoisomers thereof wherein R1 -R4 and ALK1 -ALK3 are as defined in the specification. Pharmaceutical compositions and...
5935518 Swimming pool treatment  
This invention relates to the treatment of pool surfaces and equipment with antimicrobial solutions which contain straight chain alkylamine compounds alone or in combination with additional...
5929039 Method for treating cardiac dysfunction and pharmaceutical compositions useful therefor  
The present invention relates generally to a method for, and pharmaceutical compositions useful in, the prophylaxis and/or treatment of cardiac dysfunction in a mammal by the administration of an...
5906996 Tetramine treatment of neurological disorders  
2,3,2 Tetramine (3,7-diazanonane-1,9-diamine) is propounded for the treatment of Parkinson's Disease and dementias characterized by mitochondrial damage in view of this compound's ability to...
5886051 Methods and compositions for the treatment of neurodegeneration  
Methods and pharmaceutical compositions in unit dosage form for treating neurodegeneration in a human or non-human animal afflicted therewith wherein the active agent is a therapeutically...
5880161 Therapeutic polyamines  
Therapeutic polyamines useful as a cancer chemotherapeutic agents, including molecules having a formula R1 --NH--(CH2)x --NH-- (CH2)x --NH-- (CH2)y --NH--(CH2)z --NH--R, wherein R1 and R2 are...
5776352 Process for treatment of water and of surfaces in contact with the said water in order to prevent the attachment of and/or to remove and/or to control macroorganisms, composition and paint for the said treatment  
The invention relates to a process for the treatment of water and of surfaces in contact with the said water in order to prevent the attachment and/or to, remove and/or to control macroorganisms,...

Matches 1 - 50 out of 85 1 2 >