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7576135 |
Diamine derivatives
A compound represented by formula (1):
Q 1 -Q 2 -T 0 -N(R 1 )-Q 3 -N(R 2 )-T 1 -Q 4 (1)
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7445771 |
Use of bis-amines to enhance the antimicrobial activity of aqueous compositions
The use of bis-amines to enhance the antimicrobial activity of pharmaceutical compositions is described. The bis-amines are particularly useful for enhancing the antimicrobial activity of aqueous...
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7374770 |
Topical composition for follicular delivery of an ornithine decarboxylase inhibitor
Polyethylene glycol ethers of alkyl alcohols having the general formula CH 3 (CH 2 ) x CH 2 (OCH 2 CH 2 ) n OH wherein x is 8 to 20 (of which ceteareth-20, steareth-20 and steareth-100 are...
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7307071 |
RAF-MEK-ERK pathway inhibitors to treat cancer
Materials and methods for treating certain cancers are described, preferably cancers that result from the up-regulation of the RAF-MEK-ERK pathway, and more preferably chronic myelogenous leukemia,...
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7276538 |
Composition and a method for treating hair loss
The use of the polyamine known as spermidine, i.e., N-(3-aminopropyl) tetraminethylenediamine, as an active principle in the preparation of a composition for pharmaceutical or dietetic use in man...
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7232846 |
Amines as anti-alcoholism agents
The oral administration to genetically alcoholic rats (from the strain UChB of the University of Chile) of a compound selected from endogenic polyamines (putrescine, spermidine, spermine),...
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7202280 |
Methods for the treatment and prevention of pancreatitis and for induction of liver regeneration
Novel methods for treating and preventing acute and/or chronic pancreatitis are described. Additionally, novel methods for inducing liver regeneration are described. The methods may comprise...
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7094808 |
Analogs of biologically active, naturally occurring polyamines, pharmaceutical compositions and methods of treatment
Polyamines having the formula:
or a salt thereof with a pharmaceutically acceptable acid wherein: R 1 -R 6 may be the same or different and are alkyl, aryl, aryl alkyl, cycloalkyl, optionally...
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7087648 |
Methods for modulating macrophage proliferation using polyamine analogs
Methods for modulating macrophage proliferation in an individual afflicted with or at risk for a macrophage-associated disease are provided. The methods employ a polyamine analog, or salt or...
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7045550 |
Polyamines and analogs for protecting cells during cancer chemotherapy and radiotherapy
Polyamine effectors are administered locally to provide protection against the adverse side-effects of chemotherapy or radiation therapy, such as alopecia, mucositis and dermatitis. Pharmaceutical...
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6951890 |
Preventing and/or treating cardiovascular disease and/or associated heart failure
Methods are provided for reducing copper values for, by way of example, treating, preventing or ameliorating tissue damage such as, for example, tissue damage that may be caused by (i) disorders of...
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6869944 |
Method for treating a patient with neoplasia by treatment with a platinum coordination complex
This invention provides a method for treating a patient with neoplasia by an adjuvant therapy that includes treatment with an antineoplastic platinum coordination complex.
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6844012 |
Use of selenium for treating patients suffering from systemic inflammatory response syndrome (SIRS), and composition for implementing said treatment
The invention concerns the use of at least a molecule containing selenium, in an amount corresponding to a daily dose of about 2 to 40 mg, even 80 mg of atomic selenium equivalent, on its own or...
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6685953 |
External preparation compositions
The present invention relates to a dermatologic preparation containing a diamide derivative represented by the following formula (1): (wherein, R 1 represents a linear or branched hydrocarbon...
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6656912 |
Methods to treat α1-antitrypsin deficiency
Inhibitors of glucosidase, especially those related to castanospermine, are effective in preventing or ameliorating conditions such as liver damage and emphysema that are present in individuals who...
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6605645 |
Linear polyamine compounds and polyamine-based anti-tumor agents
Nobel polyamine compounds and polyamine compounds having carcinostatic action are provided. There are also provided anticancer agents containing as active ingredient at least one of polyamine...
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6541038 |
Method for treating wood with a metal-containing treating agent and wood treated thereby
A method for treating wood, characterized by impregnating wood with a metal-containing treating agent containing lignin and/or lignin derivatives and a metal, a metal compound, and/or a metal ion...
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6482833 |
Immunotherapeutic anti-cancer pharmaceutical compositions
There is disclosed a class of pharmaceutical compositions useful for the treatment of cancer, particularly solid tumors, and having a mechanism of action as spermine antagonists. The present...
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6464764 |
Protective agents for wood
Solvent-free coating materials and treating agents used as water-based wood or material protective agents containing emulsifiable binding agents, quaternary ammonium compounds and optional...
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6444230 |
Synergistic composition of peracetic acid and amine oxide
Composition in the form of an aqueous solution, useful for disinfecting hard surfaces comprises: a) from 0.0005% to 20% by weight of peracetic acid, b) from 0.001% to 45% by weight of acetic acid,...
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6399106 |
Method for maintaining freshness of cut flower
A method for maintaining the freshness of a cut flower is disclosed. The method comprises the step of causing a flowering plant to imbibe an aqueous solution of a composition for maintaining the...
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6342534 |
Analogs of biologically active, naturally occurring polyamines, pharmaceutical compositions and methods of treatment
Polyamines having the formula: or a salt thereof with a pharmaceutically acceptable acid wherein: R 1 -R 6 may be the same or different and are alkyl, aryl, aryl alkyl, cycloalkyl, optionally...
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6217914 |
Ascorbic acid composition and method for treatment of aging or damaged skin
An ascorbic acid-based composition and related method for the treatment of aging or photo-damaged skin is disclosed. The composition includes water and ascorbic acid, at least a portion of which...
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6197822 |
Neuropeptide antagonists
The compound ##STR1## is a neuropeptide Y antagonist and is effective in treating feeding disorders, cardiovascular diseases and other physiological disorders.
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6184254 |
Methods of identifying modulators of perivascular sensory nerve Ca2+ receptors
Methods of identifying compounds that relax or stimulate arterial tension through their action on perivascular sensory nerve calcium receptors are described. Compounds identified through such...
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6168808 |
Synergistic composition of peracetic acid and amine oxide
Composition in the form of an aqueous solution, useful for disinfecting hard surfaces comprises: a) from 0.0005% to 20% by weight of peracetic acid, b) from 0.001% to 45% by weight of acetic...
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6139879 |
Fungicidal and bactericidal compositions for plants containing compounds in the form of heavy metal
The present invention relates to heavy metal chelate compositions, which are used as fungicides and bactericides, and methods of using the compositions. In particular, the present invention relates...
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6015828 |
Chemical modification of chloride channels as a treatment for cystic fibrosis and other diseases
This invention relates generally to medical treatment methods. Specifically, the invention relates to methodology for the correction of defective chloride transport by activation of chloride...
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6011066 |
Method for treating septic shock
A method for the treating septic shock in a patient comprises administering to the patient a therapeutically-effective amount of a composition comprising a compound having the formula (I): ##STR1##...
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6008188 |
Cytokine potentiator and pharmaceutical formulation for cytokine administration
A cytokine activity enhancer comprising an ethanolamine derivative of the following general formula (I) or a salt thereof, or comprising it along with cytokine or a cytokine production promoter;...
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5945432 |
Thrombolytic agents and thienopyridine derivatives in acute stroke
Methods and products are provided for treating thromboembolic stroke. A method involves the administration of a thienopyridine derivative in combination with a thrombolytic agent to a patient...
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5760091 |
Preventive agents against adhesion of marine organisms and methods of preventing such adhesion of marine organisms
A preventive agent against adhesion of a marine organism comprising: at least one amine compound represented by the following formula (I): ##STR1## , wherein R is a C 8 -22 saturated or unsaturated...
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5719193 |
Method of potentiating cell-mediated immunity utilizing polyamine derivatives
This invention relates to a method of potentiating cell-mediated immunity which comprises administering to a patient a cell-mediated immunity potentiating amount of a compound of the formula: ...
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5648355 |
Method of treatment of endogenous, painful gastrointestinal conditions of non-inflammatory, non-ulcerative origin
A method for treating endogenous, painful gastrointestinal conditions of non-inflammatory, non-ulcerative origin, such as abdominal migraine and irritable bowel syndrome, entails administering a...
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5554656 |
Disinfectant concentrates and disinfectants on amine and alcohol base and their use
The invention relates to a disinfectant concentrate which contains amine and alcohol wherein the alcohol component includes at least one glycol ether of limited miscibility with water and the amine...
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5516807 |
Method for treating vascular proliferative disorders following balloon angioplasty
Polyamines inhibit vascular smooth muscle proliferation and thus are useful in treating and preventing vascular proliferative disorders such as restenosis following balloon angioplasty.
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5494935 |
Methods for oral decorporation of metals
Several new powerful chelating agents, suitable for the removal of a variety of certain heavy metal ions from the body of a mammal by oral application, have been synthesized and tested....
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5405599 |
Method and composition for deterring criminals
A sprayable composition for deterring criminals, e.g., muggers, robbers, rapists, etc., consists essentially of a sprayable lachrymatory agent, such as MACE (chloroacetophenone) or...
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5403862 |
Method for oral decorporation of metals
Several new powerful chelating agents, suitable for the removal of a variety of certain heavy metal ions from the body by oral application, have been synthesized and tested. Structurally, these...
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5393545 |
Composition active against botulism
This invention relates to a composition of food having animal and/or vegetable origin which contains lysozyme and a chelating agent in amounts that are effective at preventing contamination of the...
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5380762 |
Method for controlling macroinvertebrates
A method is disclosed for controlling macroinvertebrates in aqueous systems, such as lakes, comprising adding to the aqueous system in recognized need of such control an effective controlling...
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5374624 |
Fluorocarbon blood substitute
The present invention relates to fluorochemical blood substitutes used for preserving mammalian tissue having lysophosphatidyl compounds in non-toxic concentrations. More specifically, the...
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5276029 |
Wood preservative compositions having activity against termites and fungi
Wood preservatives contain a copper salt, a polyamine and a fatty amine and are used for preserving wood from fungi and termites.
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5180743 |
Anti-inflammatory and analgesic compounds, related compositions and methods for preparation and use thereof
This application relates to an anti-inflammatory, immunosuppressive and analgesic composition, a method for its preparation, a pharmaceutical composition including it and a method of treating...
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5124358 |
Effect of transglutaminase inhibition on microfilariae development and macrofilariae viability
A method is described for blocking maturation and production of microfilariae in adult filarial nematodes utilizing a transglutaminase inhibitor, such as monodansyl cadaverine (MDC). Experiments...
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5087452 |
Therapeutic product based on an organic compound of silicon and polycarboxylated polyamine, particularly useful in the treatment of atheroma
Therapeutic product based on an organic derivative of silicon, particularly useful in the treatment of vascular diseases. The organic silicon compound is associated with a polyamine carrying...
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5063249 |
Nonirritating teat dip and method
A nonirritating germicidal animal test dip comprising certain dodecylaminolkylamine derivatives, an emollient and a film-forming ingredient. A method for controlling mastitis in dairy cows is also...
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5019564 |
Non-clay agricultural granule
An agricultural granule capable of carrying and releasing incorporated biocidal or nutritional agricultural chemicals. The granule is formed by the agitative agglomeration of a plant fiber slurry...
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4935449 |
N-2,3-butadienyl tri- and tetraaminoalkane derivatives
The importance of polyamines in biological systems is discussed as well as the implications of polyamines in the treatment of various diseases. Novel N-substituted-2,3-butadienyl tri- and...
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4507321 |
Epithelial cell growth regulating composition containing polyamines and a method of using same
Disclosed herein are compositions containing aliphatic di- and polyamine, or agmatine which are useful to regulate, i.e., stimulate or inhibit, epithelial cell growth. The compositions containing...
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