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7445771 |
Use of bis-amines to enhance the antimicrobial activity of aqueous compositions
The use of bis-amines to enhance the antimicrobial activity of pharmaceutical compositions is described. The bis-amines are particularly useful for enhancing the antimicrobial activity of aqueous...
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7414154 |
Polyamine compounds and compositions for use in conjunction with cancer therapy
The invention provides novel polyamine compounds and pharmaceutical compositions for administration in conjunction with cancer chemotherapy or radiation therapy. The compounds are administered...
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7201854 |
Active compound combinations for protecting animal hides and leather
The present application relates to the use of active compound combinations containing phenolic active compounds and fungicidal active compounds for preserving animal hides and leather.
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6908948 |
DNA-cleaving antitumor agents
A chemical composition and method of use of the composition is described. The chemical composition includes an aza-enediynes, aza-enyne allenes, or an aza-diallenes. These compound are preferably...
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6830754 |
Amphipatic lipid dispersion
Described in the present invention are a dispersion which comprises, as a dispersoid, (a) 5 to 40 wt. % of an amphipatic lipid containing, in the molecule thereof, at least one hydroxy and amide...
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6809120 |
Composition containing propargylamine for enhancing cancer therapy
Antineoplastic drug modulators are described. The specific modulators referred to are propargylamines which can enhance the cytotoxic effects of antineoplastic drugs on cancer cells while...
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6727288 |
Method for treating bone fracture
The present invention relates to a method for treating or preventing bone fracture, which comprises administering an effective amount of calcium L-threonate to a subject in need of such prevention...
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6713513 |
Method for treating cartilage related diseases
The present invention relates to a method for preventing or treating of cartilage related diseases, such as osteoarthritis, rheumatoid arthritis, articular cartilage damage, multiple chondritis,...
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6649587 |
Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases
Peptide conjugates in which cytocidal and cytostatic agents, such as polyamine analogs or naphthoquinones, are conjugated to a polypeptide recognized and cleaved by enzymes such as...
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6605641 |
20-HETE antagonists and agonists
20-HETE agonists and antagonists are disclosed along with therapeutic applications. In a preferable form of the invention, the 20-HETE agonists are selected from the group consisting of...
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6599941 |
Insecticide and insect repellant compositions
A non-toxic, environmentally safe and easily employable insecticide and insect repellent is achieved by providing an aqueous composition incorporating ethanolamine based compounds, either...
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6582683 |
Dermal barrier composition
Disclosed is a dermal barrier composition which contains a hydrophilic polymer emulsion and a hydrophobic polymer emulsion. The dermal barrier composition is moisture activated, and remains inert...
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6482833 |
Immunotherapeutic anti-cancer pharmaceutical compositions
There is disclosed a class of pharmaceutical compositions useful for the treatment of cancer, particularly solid tumors, and having a mechanism of action as spermine antagonists. The present...
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6251950 |
Aliphatic propargylamines as cellular rescue agents
The present invention relates to the use of a group of propargylamines of the general formula (I) ##STR1## wherein R 1 is hydrogen or CH 3 and R 2 is (CH 2 ) n CH 3 and n is an integer from 0...
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6153648 |
Iodopropargylamine compounds, and industrial antimicrobial and antifungal agents, algicides, and antifouling agents containing the same
Iodopropargylamine compound of the general formula (1): ##STR1## wherein R 1 and R 2 each independently represent a hydrogen atom or an alkyl group having 1 to 3 carbon atoms, or R 1 and R 2 ...
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6103768 |
Fatty acid based compositions and methods for the control of plant infections and pests
The invention described here concerns the unique utility of fatty acids and their derivatives to eradicate existing fungal and bacterial infections in plants. Also, described herein are combination...
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6077872 |
Use of calcium L-threonate in preventing, inhibiting and curing osteoporosis and rickets
The present invention relates to the use of calcium L-threonate, namely, to a method for preventing, inhibiting and curing osteoporosis and rickets using calcium L-threonate.
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6028114 |
Use of aminothiolester derivatives in pharmaceutics
Use of at least one aminothiol ester derivative for the preparation of a pharmaceutical composition intended to increase the inhibition of a character resistant to the induction of apoptosis of...
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6004958 |
Compounds and methods for therapeutic intervention in preventing diabetic complications and procedures for assessing a diabetic's risk of developing complications and determining the efficacy of therapeutic intervention
The present invention is based on the discovery of a metabolic pathway in which a specific kinase converts fructose-lysine into fructose-lysine-3-phosphate in an ATP dependent reaction....
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5859017 |
Method for inhibiting mast cell and basophil activation
In a method for treating or preventing allergy or allergic disorders an effective amount of a compound that inhibits intracellular generation of phosphatidic acid and diacylglycerol is...
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5824693 |
Method for treatment for pulmonary disease
The present invention provides a method for treating pulmonary disease. More specifically, the present invention provides a method for treating diseases such as adult respiratory distress syndrome...
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5760091 |
Preventive agents against adhesion of marine organisms and methods of preventing such adhesion of marine organisms
A preventive agent against adhesion of a marine organism comprising: at least one amine compound represented by the following formula (I): ##STR1## , wherein R is a C 8 -22 saturated or unsaturated...
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5653973 |
Lepidoptera bait
Baits useful for controlling lepidoptera populations is made with (a) a diet component for lepidoptera; (b) a toxicant; (c) a chemiluminescent, visual attractant and (d) an encapsulating agent that...
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5599847 |
Antifungal compounds
Compounds having the formula (I) below: (R 1 R 2 N)CH 2 --CHCH--CH 2 (NR 3 R 4 )(I) wherein R 1 , R 2 , R 3 and R 4 , which may be the same or different represent hydrogen atoms, an...
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5587366 |
Compositions useful in prophylaxis and therapy of endotoxin related conditions
Treatment and prophylaxis of endotoxin caused toxicity is disclosed. This is accomplished by administering phospholipid containing compositions to the subject. The compositions are protein and...
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5587367 |
Pharmaceutical or cosmetic composition containing a combination of a retinoid and a sterol
A pharmaceutical or cosmetic composition is disclosed comprising in combination a retinoid and a sterol capable of inhibiting the biosynthesis of cholesterol resulting in a synergistic effect in...
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5561163 |
Treating hearing loss with deprenyl
Selegiline and pharmaceutically acceptable analog forms thereof are used as treatments for hearing loss in mammals, especially dogs.
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5508311 |
Aliphatic propargylamines as selective MAO-B inhibitors and as neuroprotective agents
The invention relates to a series of propargylamines, their salts and pharmaceutical compositions containing a compound of formula (III) wherein R 1 , R 3 and R 4 are the same or different and...
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5446027 |
Amide derivative and external skin care preparation containing the same
Amino derivatives represented by the following general formula (1): ##STR1## and external skin care preparations containing such an amide derivative, are useful for preventing or curing skin...
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5436273 |
Psychoactive propargylamine derivatives used in the treatment of anxiety, psychotic states or aggression
Propargylamine derivatives having the general formula: ##STR1## wherein R is a hydrogen atom, an unsubstituted phenyl group or a phenyl group substituted with halogen, trifluoromethyl, loweralkoxy,...
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5434186 |
Carboxylic acid leukotriene B.sub.4 antagonists
Compounds of the formula ##STR1## wherein X is O or CH 2 ; Y is O, --CH 2 --CH 2 --, --CHCH--, --C.tbd.C--, or --OCH 2 C 6 H 4 --; Z is --CH 2 --CH 2 --, --CHCH-- or --C.tbd.C--; ...
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5391548 |
Transdermal flux enhancing compositions to treat hypertension, diabetes and angina pectoris
A transdermal flux enhancing pharmaceutical composition for transdermal administration to a human or lower animal subject comprising a safe and effective amount of a pharmacologically active...
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5389300 |
Agent for protecting sawn timber
The present invention relates to an agent or concentrate for protecting sawn timber against wood-discolouring fungi, containing a fungicide on phenol basis and a fungicide on organo-iodine basis,...
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5322856 |
Fortified glutaraldehyde chemical sterilant/disinfectant
A fortified glutaraldehyde compound with and without dual synergistic phenols is provided for disinfection and sanitization. One formula consists of: glutaraldehyde; dual quaternary ammonium...
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5248494 |
Method of reducing anthralin induced inflammation and staining
A lenitive composition is provided for application to the skin of an anthralin patient for reducing anthralin-induced inflammation and the staining associated with anthralin use. The lenitive...
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5169868 |
Aliphatic propargylamines as specific MAO-B inhibitors
A component having the following formula I: ##STR1## wherein X represents an integer ranging from 1 to 2 or 7 to 13; Y represents an integer ranging from 0 to 5; Z represents an integer...
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5132293 |
Enzymic alteration of hair growth
The rate and character of mammalian hair growth is altered by topical application to the skin of a composition containing a dermatologically acceptable carrier and an inhibitor of...
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4935449 |
N-2,3-butadienyl tri- and tetraaminoalkane derivatives
The importance of polyamines in biological systems is discussed as well as the implications of polyamines in the treatment of various diseases. Novel N-substituted-2,3-butadienyl tri- and...
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4868219 |
Treatment of skin diseases with aliphatic amines
Noninfectious inflammatory skin diseases in which bacteria or yeasts play a significant adjunctive role are treated with topical formulations of aliphatic amines containing 9 to 18 carbon atoms,...
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4851447 |
N-2,3-butadienyl-1,4-butanediamine derivatives
1. A compound of the formula: H 2 CCCHCH 2 NHCH 2 --Z--CH 2 NHR wherein: Z is --CH 2 CH 2 -- or trans--CHCH--, R is H, CH 3 --, CH 3 CH 2 , CH 3 (CH 2 ) 2 --, --(CH 2 ) 3...
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4720489 |
Hair growth modification with ornithine decarboxylase inhibitors
The rate and character of human hair growth including androgen-stimulated beard hair growth in intact, sexually mature males is altered by the topical application out of a dermatologically...
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4707498 |
Fluorinated diaminoalkyne derivatives
Novel fluorinated diaminoalkyne derivatives are inhibitors of ornithine decarboxylase enzyme and have the following general Formula I: ##STR1## wherein R represents C 1 -C 4 alkyl, or preferably,...
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4665069 |
Analgesic composition and method of relieving pain
An analgesia composition comprising an aqueous solution of a neurologically active agent in a concentration of from about 10 -3 to about 10 -13 grams/ml and a method of relieving pain comprising...
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4522827 |
Method of treating acute pancreatitis with isometheptene
A method of relieving the symptoms of acute pancreatitis comprising administering Isometheptene to a person afflicted with that condition.
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4423073 |
Fluorinated diaminopentene derivatives
Novel fluorinated alkenylene diamine derivatives are inhibitors of ornithine decarboxylase enzyme and have the following general Formula I: ##STR1## wherein: R c represents hydrogen or --COR 5 ,...
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4421768 |
Fluorinated diamino-heptene and-heptyne derivatives
Novel fluorinated diamino-heptene and-heptyne derivatives are inhibitors of ornithine decarboxylase enzyme involved in polyamine formation and have the following general Formula I: ##STR1##...
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4410509 |
Synthetic fly attractants
Synthetic organic compounds that have certain functional groups incorporated into a 23-atom chain are useful as fly attractants. Novel compounds have the general formula ##STR1## where X is --S--,...
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4310547 |
Control of parasitic ticks
Certain amines are highly effective in controlling parasitic ticks.
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4265910 |
Isoprenylamines
This invention relates to new isoprenylamines and the acid addition salts thereof. Further, the invention is concerned with antiviral agents for vertebrate animal, said agents containing as their...
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4207315 |
Process for treating proliferative skin diseases using certain diamino compounds
A process and pharmaceutical compositions for alleviating proliferative skin diseases such as psoriasis, atopic dermatitis, etc., comprising administering to humans or domesticated animals,...
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