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7612238 |
Amino-propanol derivatives
Compounds of formula I
wherein R 1 , R 2 , R 3 , R 4 and R 5 are as defined in the specification, processes for their production, their uses and pharmaceutical compositions containing them.
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7582765 |
Aryl aniline β2 adrenergic receptor agonists
The invention provides novel β 2 adrenergic receptor agonist compounds of formula (I):
wherein R 1 -R 13 and w have any of the values described in the specification. The invention also...
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7566705 |
Combination of formoterol and mometasone furoate for asthma
A medicament containing, separately or together, (A) formoterol or a pharmaceutically acceptable salt thereof or a solvate of formoterol or a solvate of the salt and (B) mometasone furoate, for...
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7550466 |
Alpha and/or β-adrenergic antagonists and agonists to treat pain
The present disclosure provides for improved methods for treating pain, including pain associated with chronic inflammatory diseases, neuropathic pain and cancer by using α-adrenergic antagonists...
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7541385 |
Bronchodilating β-agonist compositions and methods
Bronchodilating compositions and methods are provided. The compositions are intended for administration as a nebulized aerosol. In certain embodiments, the compositions contain formoterol, or a...
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7524887 |
2-amino-1,3-propanediol compounds for the treatment of acute pain
The present invention relates to a method for the prophylaxis or treatment of pain using compounds of formula I,
in which R, R2, R3, R4 and R5 have the meanings indicated in the specification.
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7491712 |
Process for preparation of paricalcitol and intermediates thereof
The invention relates to a novel process for the preparation of Paricalcitol and intermediates thereof.
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7482491 |
Amino alcohol derivative, addition salt thereof, and immunosuppressant
An amino alcohol derivative represented by the following general formula (1) (for example, (±)-2-amino-5-[4-(3-benzyloxyphenylthio)-2-chlorophenyl]-2-
methylpentane-1-ol) exhibits strong...
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7462645 |
Bronchodilating beta-agonist compositions and methods
Bronchodilating compositions and methods are provided. The compositions are intended for administration as a nebulized aerosol. In certain embodiments, the compositions contain formoterol, or a...
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7456222 |
Anti tubercular drug: compositions and methods
Methods and compositions for treating disease caused by infectious agents, particularly tuberculosis. In particular, methods and compositions comprising substituted ethylene diamines for the...
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7442839 |
Phenethanolamine derivative for the treatment of respiratory diseases
The present invention relates to novel compounds of formula (I),
to a process for their manufacture, to pharmaceutical compositions containing them, and to their use in therapy, in particular...
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7432247 |
Methods of cardioprotection using dichloroacetate in combination with an inotrope
The present invention provides compositions and methods for maintaining cardiac function by administering dichloroacetate (DCA) in combination with an inotrope.
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7431916 |
Administration of medicinal dry powders
A method of administering a metered dry powder combined dose of finely divided dry medication powders is disclosed, wherein said method comprises providing a relative motion between a nozzle of a...
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7429390 |
Stable pharmaceutical compositions, processes for making the same and methods of their use
The present invention is generally related to alcohol free, liquid ranitidine formulations for oral administration. In particular, the present invention is related to stable, syrup formulations...
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7427639 |
β2-adrenergic receptor agonists
Disclosed are multibinding compounds which are β2 adrenergic receptor agonists and are useful in the treatment and prevention of respiratory diseases such as asthma, bronchitis. They are also...
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7402673 |
Diamine β2 adrenergic receptor agonists
The invention provides novel β 2 adrenergic receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat...
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7354913 |
High storage stability inhalable compositions
Inhalable pharmaceutical compositions are provided, for use in the treatment of respiratory disorders such as asthma, rhinitis and chronic obstructive pulmonary disease (COPD). These compositions...
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7268149 |
Cyclothiocarbamate derivatives as progesterone receptor modulators and methods of treating skin disorders
The present invention provides methods of treating skin disorders includes delivering to a mammal a composition containing a compound of formula I, or tautomers thereof, in a regimen, wherein...
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7253211 |
(R)-chiral halogenated substituted fused heterocyclic amino compounds useful for inhibiting cholesterol ester transfer protein activity
The invention relates to substituted aryl and heteroaryl (R)-Chiral Halogenated 1-Substitutedamino-(n+1)-Alkanol compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma...
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RE39593 |
1-phenyl-3-dimethylaminopropane compounds with a pharmacological effects
1-phenyl-3-dimethylaminopropane compounds corresponding to the formula I
a method of preparing them, and the use of these substances as analgesic active ingredients in pharmaceutical...
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7135500 |
Dihydroxymethylphenyl derivatives, processes for preparing them, and their use as pharmaceuticals
A compound of formula 1
wherein the groups R 1 , R 2 , R 3 , and R 4 may have the meanings given in the claims and in the specification, processes for preparing them, and their use as...
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7135497 |
Treating neural conditions resulting from spinal cord contusions and other causes
β 2 -agonists, such as clenbuterol and salbutamol can enhance the recovery of locomotive function and/or neuromuscular strength following spinal cord injuries or as a result of degenerative neural...
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7125892 |
Aryl aniline β2 adrenergic receptor agonists
The invention provides novel β 2 adrenergic receptor agonist compounds of formula (I):
wherein R 1–R 13 and w have any of the values described in the specification. The invention also...
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7107985 |
Pharmaceutical combination
The present invention relates to a combination comprising (a) an adenosine A 2a receptor agonist as define herein and (b) an adrenergic β2 receptor agonist, for simultaneous, sequential or...
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7094429 |
Process for preparing tannate liquid and semi-solid dosage forms
An active ingredient from the group of an antihistamine, a decongestant, an antitussive or anticholinergic is dissolved in a suitable solvent and added to a dispersion of tannic acid in water to...
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7067502 |
Combinations of formoterol and mometasone furoate for asthma
A medicament containing, separately or together, (A) formoterol or a pharmaceutically acceptable salt thereof or a solvate of formoterol or a solvate of the salt and (B) mometasone furoate, for...
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7060730 |
Rapidly absorbed liquid compositions
The present invention provides a method which provides for a faster absorption of pharmaceutically acceptable amines. The method provides a pharmaceutically acceptable amine in combination with a...
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7056936 |
Synergistic combination
The invention relates to the combined administration of PDE inhibitors and β 2 adrenoceptor agonists for the treatment of respiratory tract disorders.
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RE39072 |
2-aminopropane-1,3-diol compounds, medicinal use thereof, and intermediates in synthesizing the same
The present invention relates to a compound of the general formula
wherein R 1 , R 2 , R 3 and R 4 are each a hydrogen or an acyl, a pharmaceutically acceptable acid addition salt thereof or...
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6979689 |
Compositions and methods for treating upper respiratory congestion
A composition of an antitussive, a decongestant, and diphenhydramine as an antihistamine to treat upper respiratory and oral pharyngeal congestion and related symptoms in a patient. In addition to...
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6974803 |
Pharmaceutical combination
The present invention relates to a combination comprising (a) an adenosine A 2a receptor agonist as defined herein and (b) an adrenergic β2 receptor agonist, for simultaneous, sequential or...
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6964976 |
Amino alcohol derivatives
Compounds of formula (I) which exhibit excellent immune suppression activity, pharmacologically acceptable salts thereof, esters thereof or other derivatives:
wherein R 1 and R 2 are a...
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6949548 |
Combination therapy for the treatment of heart failure
A combination therapy for the treatment of heart failure comprises administering a combination of levosimendan or a pharmaceutically acceptable salt thereof and a beta-adrenergic receptor...
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6926906 |
Orally administrable pharmaceutical formulation
The present invention relates to a pharmaceutical formulation for oral administration through a soft gelatin capsule drug delivery device, wherein the pharmaceutical formulation has Pseudoephedrine...
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6900203 |
Optically active fluorinated vasoconstrictors, methods for making them, and anesthetic formulations comprising them
(R)-6F-phenylephrine, essentially free of (S)-6F-phenylephrine, and an anesthetic formulation comprising (R)-6F-epinephrin or (R)-6F-phenylephrine and having improved stability compared to...
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6869618 |
Process for preparing tannate liquid and semi-solid dosage forms
An active ingredient from the group of an antihistamine, a decongestant, an antitussive or anticholinergic is dissolved in a suitable solvent and added to a dispersion of tannic acid in water to...
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6849662 |
Therapeutic uses for nitric oxide inhibitors
The present invention is based on the discovery that nitric oxide (NO) is an important growth regulator in an intact developing organism. In particular, the present invention relates to a method of...
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6846492 |
Use of phenylethylamine derivatives for the antimicrobial treatment of surfaces
The use of compounds of formula (1) is described, in which compounds R 1 , R 2 and R 3 are each independently of the others hydrogen; C 1 -C 20 alkyl; C 3 -C 7 cycloalkyl; C 2 -C 20 alkenyl; C 4...
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6841575 |
Use of 1-phenyl-3-dimethylaminopropane compounds for treatment of urinary incontinence
The invention relates to the use of 1-phenyl-3-dimethylaminopropane compounds for treating increased urinary urgency or urinary incontinence, as well as to the production of corresponding medicaments.
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6818672 |
Treating endometriosis or infertility, or improving fertility
The present invention concerns compositions and methods for using a β-adrenergic agonist for treating endometriosis, for treating infertility, and for improving fertility. The present invention...
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6814953 |
Bronchodilating compositions and methods
Bronchodilating compositions and methods are provided. The compositions are intended for administration as a nebulized aerosol. In certain embodiments, the compositions contain formoterol, or a...
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6787553 |
Methods for remodeling neuronal and cardiovascular pathways
The present invention provides a method of administration of an agent which acts to remodel neuronal or vascular pathways for the long term management of sexual dysfunction in both males and...
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6784175 |
Use of substituted 1-amino-5-phenylpentane-3-ol and/or 1-amino-6-phenylhexane-3-ol compounds as medicaments
The use of at least one substituted 1-amino-5-phenylpentane-3-ol and/or 1-amino-6-phenylhexane-3-ol compound and/or one of the enantiomers thereof and/or one of the diastereomers thereof and/or one...
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6765022 |
Cyclohexylamine derivatives as subtype selective nmda receptor antagonists
Described are cyclobexylamine derivatives of Formula I, Formula II, or Formula III and their pharmaceutically acceptable salts thereof: The compounds are antagonists of NMDA receptor channel...
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6730706 |
Treatments using venlafaxine
This invention provides a method of treating obesity, generalized anxiety disorder, post-traumatic stress disorder, late luteal phase dysphoric disorder (premenstrual syndrome), attention deficit...
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6706743 |
β3 adrenergic receptor agonists and uses thereof
The instant invention provides β 3 adrenergic receptor agonists of structural Formula (I), the stereoisomers and prodrugs thereof, and the pharmaceutically acceptable salts of the compounds,...
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6703044 |
Venlafaxine formulations
The invention provides a method for treating a subject with venlafaxine, comprising administering to the subject a formulation having a therapeutically effective amount of venlafaxine or a...
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6696472 |
Substituted N-phenoxy-N-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity
The invention relates to substituted polycyclic aryl and heteroaryl tertiary-heteroalkylamine compounds useful as inhibitors of cholesteryl ester transfer protein (CETP; plasma lipid transfer...
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6686388 |
Regulators of the hedgehog pathway, compositions and uses related thereto
The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function, ptc loss-of-function or smoothened gain-of-function...
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6677381 |
Guaifenesin tannate
The invention pertains to a novel composition comprising guaifenesin tannate and to a method for preparing guaifenesin tannate by reacting guaifenesin with tannic acid at a temperature above the...
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