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6649587 |
Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases
Peptide conjugates in which cytocidal and cytostatic agents, such as polyamine analogs or naphthoquinones, are conjugated to a polypeptide recognized and cleaved by enzymes such as...
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6635678 |
Pharmaceutical composition for treating fecal incontinence
Fecal incontinence and anal itch can be treated by administration, more particularly by local application to the anus, of an a adrenergic blocker, nitric oxide synthase inhibitor, prostaglandin F...
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6624200 |
Bioadhesive progressive hydration tablets
A bioadhesive composition wherein the active ingredient may be protected from water or the surrounding environment, thereby protecting it from metabolism or from other degradation caused by...
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6602912 |
Transdermal administration of phenylpropanolamine
Methods and systems are provided for the transdermal administration of racemic phenylpropanolamine, i.e., a mixture of two or more of the four isomers of phenylpropanolamine, (+)-norephedrine,...
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6566396 |
Antitussive/antihistaminic compositions
Tannate compositions consisting essentially of carbetapentane tannate and chlorpheniramine tannate which are effective when administered orally for the symptomatic relief of coryza associated with...
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6559139 |
Combination chemotherapy
This invention relates to combination chemotherapy, particularly involving vitamin D or a derivative thereof. In one aspect, the invention provides a method of killing a cell by first administering...
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6555583 |
Therapies for treating pulmonary diseases
This invention relates to treating pulmonary diseases such as chronic obstructive pulmonary disease or asthma by administering a phosphodiesterase 4 inhibitor in combination with beta adrenergic...
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6552014 |
Methods of inhibiting platelet activation with selective serotonin reuptake inhibitors
The present invention pertains to methods for reducing the platelet activation state in an individual comprising administering a selective serotonin reuptake inhibitor (SSRI). The platelet...
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6552045 |
Methods and compositions using (&plus ) norcisapride in combination with proton pump inhibitors or H2 receptor antagonists
The invention relates to methods and compositions for the prevention, treatment, or management of gastrointestinal disorders or symptoms thereof, employing two or more agents or compounds to...
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6548518 |
Methods of treating gastro-esophogeal reflux disease using (-) norcisapride in combination with proton pump inhibitors or H2 receptor antagonists
The invention relates to methods and compositions for the prevention, treatment, or management of gastrointestinal disorders or symptoms thereof, employing two or more agents or compounds to...
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6548534 |
Nonsteroidal gestagens
This invention describes the new, nonsteroidal gestagens of general formula I in which A, B, Ar 1 , R 1 , R 2 and R 3 have the meanings that are indicated in more detail in the description....
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6545057 |
Tricyclic antidepressants and their analogues as long-acting local anesthetics and analgesics
Methods and compositions of tricyclic antidepressants for inducing local long-lasting anesthesia and analgesia are provided. The methods and compositions are useful for alleviating acute and...
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6503950 |
Triple drug therapy for the treatment of narcotic and alcohol withdrawal symptoms
A triple drug, pharmaceutical kit, composition, and method of treatment containing a combination of effective amounts of at least one anxiolytic agent, at least one centrally acting alpha...
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6500849 |
1-alkyl-, 1-alkenyl-, and 1-alkynylaryl-2-amino 1,3-propanediols and related compounds
Novel 1-alkyl-, 1-alkenyl-, and 1-alkynylaryl-2-amino-1,3-propanediols, intermediates and processes for the preparation thereof, and methods of reducing inflammation and cell proliferation, and...
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6489329 |
Pharmaceutical compositions for the treatment of rhinitis
A pharmaceutical composition comprising a therapeutically effective amount of a mixture consisting essentially of (i) pseudoephedrine, an individual optical isomer or a pharmaceutically acceptable...
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6485758 |
Hangover treatment
A cure for a hangover containing the active ingredient ephedrine in powdered form enclosed in a capsule. In a second embodiment this cure contains ephedrine and charcoal, while in a third...
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6486206 |
Mechanical and pharmacologic therapies to treat cardiac arrest
A method for resuscitating a patient from cardiac arrest, comprising: (a) administering CPR, and (b) administering: i) an amount of one or more vasopressor agents, or one or more vasopressinergic...
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6451289 |
Albuterol formulations
Albuterol formulations packaged in an oxygen-permeable plastic container have a long shelf life at room temperature. The formulations consist essentially of albuterol or a pharmaceutically...
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6444708 |
Treatment using venlafaxine
This invention provides a method of treating obesity, generalized anxiety disorder, post-traumatic stress disorder, late luteal phase disphoric disorder (premenstrual syndrome), attention deficit...
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6417206 |
Antitussive/antihist aminic/decongestant compositions
Tannate compositions are disclosed consisting essentially of carbetapentane tannate, pyrilamine tannate and phenylephrine tannate are effective when administered orally for the symptomatic relief...
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6414033 |
Drug dosage form based on the teorell-meyer gradient
A method for delivery of pharmaceutically effective amounts of drugs and therapeutic ions is disclosed. More particularly, a method of formulating a dosage form that will move drugs, pro-drugs or...
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6403645 |
Antidepressant effect of norepinephrine uptake 2 inhibitors and combined medications including them
Norepinephrine uptake 2 inhibitors (or their precursors) are administered to enhance the effect of norepinephrine reuptake inhibitors and other antidepressants. The uptake 2 inhibitor may be...
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6376531 |
Method of treatment using deuterium compounds
The present invention provides organic deuterium compounds which can be therapeutic compounds to treat manic depression. In particular, the present invention relates to deuterated methionine,...
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6372800 |
Benzene compound and pharmaceutical use thereof
A benzene compound of the formula wherein each symbol is as defined in the specification; an optically active isomer or salt thereof, a medicinal composition containing the same, and an...
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6369051 |
Combinations of SSRI and estrogenic agents
This invention comprises methods of depression, anxiety, generalized anxiety disorder (GAD), hot flush, post partum depression, premenstrual syndrome, obesity, obsessive compulsive disorder,...
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6369114 |
Administration of an α2-adrenergic receptor agonist to enhance cardiopulmonary resuscitation
Methods, formulations and kits are described for resuscitating a patient suffering from cardiac arrest, for enhancing the efficacy of cardiopulmonary resuscitation, for treating post-resuscitation...
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6362202 |
Methods and compositions using (−) norcisapride in combination with proton pump inhibitors or H2 receptor antagonists
The invention relates to methods and compositions for the prevention, treatment, or management of gastrointestinal disorders or symptoms thereof, employing two or more agents or compounds to...
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6358944 |
Methods and compositions for treating generalized anxiety disorder
The present invention relates to methods and compositions comprising a very low dose of cyclobenzaprine or metabolite thereof for preventing and treating Generalized Anxiety Disorder. The present...
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6359012 |
Method for making 24(S)-hydroxyvitamin D2
The invention provides a method for making 24(S)-hydroxyvitamin D 2 which is a stereospecific synthesis.
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6353005 |
Method and compositions using (&plus ) norcisapride in combination with proton pump inhibitors or H2 receptor antagonist
The invention relates to methods and compositions for the prevention, treatment, or management of gastrointestinal disorders or symptoms thereof, employing two or more agents or compounds to...
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6342496 |
Bupropion metabolites and methods of use
Methods are disclosed which utilize metabolites of bupropion for treating disorders ameliorated by inhibition of neuronal monoamine reuptake. Such disorders include, cerebral function disorders,...
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6340482 |
Methods for inducing weight loss in a human with materials derived from Citrus varieties
Materials derived from Citrus plants can be administered orally to humans for the purpose of producing or maintaining weight loss as well as improving the person's physical performance and...
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6340481 |
Regulation of athletic function with materials derived from citrus varieties
Materials derived from Citrus plants can be administered orally to humans for the purpose of producing or maintaining weight loss as well as for improving the person's physical performance and...
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6337328 |
Bupropion metabolites and methods of use
Methods are disclosed which utilize metabolites of bupropion for treating sexual dysfunction.
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6333359 |
Regulation of cellular apoptosis using modulators of β-AR receptors
The invention concerns the use of β2-adrenergic modulators for regulating cellular apoptosis.
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6316499 |
Methods for increasing the muscle mass of a human with materials derived from citrus varieties
Materials derived from Citrus plants can be administered orally to humans for the purpose of producing or maintaining weight loss as well as for improving the person's physical performance and...
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6303145 |
(S,R) formoterol methods and compositions
A method and composition are disclosed utilizing the pure (S,R) isomer of formoterol, which is a bronchodilator with reduced adverse effects. (S,R)-Formoterol may be conveniently and safely...
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6297288 |
Method of preventing the effects of altered Δ-5 pathway steroidogenesis in adrenergically blockaded conditions
The production of sex steroids by the Δ-5 steroidogenic pathway has been found to be under control of the adrenergic nervous system, and sex steroids produced by this pathway are diminished in...
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6287597 |
Antihistaminic/decongestant compositions
Tannate compositions consisting essentially of pyrilamine tannate and phenylephrine tannate which are effective when administered orally for the symptomatic relief of coryza associated with the...
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6287540 |
Formulation for inhalation
A dry powder composition comprising one more potent pharmaceutically active substances and a carrier substance, all of which are in finely divided form, wherein the formulation has a poured bulk...
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6284765 |
(+) naloxone and epinephrine combination therapy
A composition formulated for dose-wise delivery to a breathing passageway of a human, the composition comprising a carrier solution containing (+)naloxone and a pharmacologically effective amount...
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6277888 |
Drug composition
The present invention provides a pharmaceutical composition containing 2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol or a pharmaceutically acceptable acid addition salt thereof and a lecithin,...
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6268383 |
Substituted aromatic compounds for treatment of antibiotic-resistant infections
This invention relates to compounds of the general formula: ##STR1## wherein A is a aromatic hydrocarbon ring system and R 1 is a carbon bound directly to an oxygen and is also bound to a nitrogen...
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6265449 |
Aqueous compositions comprising ranitidine and LCMT sucrose
The invention relates to an aqueous pharmaceutical composition for oral administration comprising ranitidine, or a pharmaceutically acceptable salt thereof, characterized in that the composition...
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6242472 |
Methods for the pulmonary delivery of biological agents
Methods of delivering a therapeutic or diagnostic agent in a perfluorochemical liquid carrier are provided. In preferred embodiments, the disclosed methods use compositions in the form of an...
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6235793 |
Use of agonists of adrenergic β-3 receptors for preparing wound-healing medicines
The invention relates to the use of β 3 -adrenergic receptor agonists for the preparation of healing drugs and to the pharmaceutical compositions for said use.
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6235725 |
Methods and compositions for the prevention of tolerance to medications
The present invention pertains to the identification of moieties and methods of using the same for preventing tolerance to bronchodilators. More specifically, the present invention pertains to the...
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6224873 |
Regulation of appetite, body weight and athletic function with materials derived from citrus varieties
Materials derived from Citrus plants can be administered orally to humans for the purpose of producing or maintaining weight loss as well as for improving the person's physical performance and...
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6214885 |
Use of polymers containing β-hydroxyalkylvinylamine units as biocides
The use of polymers containing β-hydroxyalkylvinylamine units, as obtainable by reacting polymers containing vinylamine units with epoxides of the formula ##STR1## in which R is C 2 -C 28 alkyl,...
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6211171 |
Use of antidepressants for local analgesia
When administered locally, tricyclic, second generation and third generation antidepressants, such as amitriptyline and desipramine, have been shown to produce analgesia in a subject having a site...
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