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7615545 |
Oral contraceptives to prevent pregnancy and diminish premenstrual symptomatology
This invention relates to a method of preventing pregnancy and treating PMS including PMDD. More particularly, the invention relates to a method, which involves administering one of several...
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7608616 |
Methods for reducing the risk of an adverse drug interaction in a patient suffering from insomnia
Disclosed herein is a method for treating a patient with Quazepam that reduces the risk of an adverse interaction between the Quazepam and drug that is a substrate of the cytochrome P450 enzyme...
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7601876 |
Compounds, compositions and methods for the treatment of amyloid diseases such as systemic AA amyloidosis
Bis- and tris-dihydroxyaryl compounds and their methylenedioxy analogs and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the...
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7589127 |
Aminoalkylphenols, methods of using and making the same
The present invention relates to Mannich base antimalarial aminoalkylphenol compounds and their use against protozoa of the genus Plasmodium , particularly emerging strains of drug-resistant...
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7585897 |
Modified release formulations of a bupropion salt
The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of...
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7576073 |
Combined therapy for the treatment of parkinson's disease
The present invention concerns a method and a pharmaceutical composition for treating the symptoms associated to Parkinson's disease. The method and the pharmaceutical composition use a combination...
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7563930 |
Crystal forms of Cinacalcet HCI and processes for their preparation
Provided are crystalline forms of Cinacalet HCl and processes for their preparation.
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7553834 |
Method for the targeted treatment of depression
A method for determining the appropriate medication for a patient suffering from depression. A patient will take a questionnaire wherein the patient answers a number of questions with scaled...
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7550466 |
Alpha and/or β-adrenergic antagonists and agonists to treat pain
The present disclosure provides for improved methods for treating pain, including pain associated with chronic inflammatory diseases, neuropathic pain and cancer by using α-adrenergic antagonists...
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7541384 |
Mesalamine suppository
The present invention relates to a mesalamine rectal suppository designed to provide improved comfort of use. One embodiment of the invention is a mesalamine rectal suppository containing...
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7528175 |
Method of treating airway diseases with beta-adrenergic inverse agonists
The use of β-adrenergic inverse agonists provides a new and highly efficient way of treating a number of pulmonary airway diseases, including asthma, emphysema, and chronic obstructive pulmonary...
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7514470 |
Aniline derivatives as selective androgen receptor modulators
This invention relates to non-steroidal compounds that are modulators of androgen, glucocorticoid, mineralocorticoid, and progesterone receptors, and also to the methods for the making and use of...
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7511073 |
Amines that inhibit a mammalian anandamide transporter, and methods of use thereof
One aspect of the present invention relates to amines. A second aspect of the present invention relates to the use of the amines as inhibitors of a mammalian anandamide transporter. The compounds...
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7504422 |
Polyamine compounds
This invention relates to methods for treating retinopathy and repairing tissue damage. The methods include administering to a subject in need thereof an effective amount of one or more compounds...
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7488759 |
Malic acid addition salts of terbinafine
The invention concerns salts of the compound of formula I
with malic acid, their preparation, corresponding pharmaceutical compositions and their use as antimycotics.
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7485320 |
Liposome for incorporating large amounts of hydrophobic substances
A liposome formulation for stably incorporating high content of hydrophobic substance is disclosed. The liposome includes two phospholipids with different phase transition temperatures such as...
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7482491 |
Amino alcohol derivative, addition salt thereof, and immunosuppressant
An amino alcohol derivative represented by the following general formula (1) (for example, (±)-2-amino-5-[4-(3-benzyloxyphenylthio)-2-chlorophenyl]-2-
methylpentane-1-ol) exhibits strong...
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7462618 |
Treatment of inflammatory autoimmune diseases with alpha-adrenergic antagonists and beta-adrenergic agonists
The present invention discloses a novel compound and method for the treatment of inflammatory autoimmune diseases, for example, rheumatoid arthritis, using α-adrenergic antagonists and...
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7456317 |
Substituted phenethylamines with serotoninergic and/or norepinephrinergic activity
Chemical syntheses and medical uses of novel inhibitors of the uptake of monoamine neurotransmitters and pharmaceutically acceptable salts and prodrugs thereof, for the treatment and/or management...
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7456222 |
Anti tubercular drug: compositions and methods
Methods and compositions for treating disease caused by infectious agents, particularly tuberculosis. In particular, methods and compositions comprising substituted ethylene diamines for the...
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7439241 |
Compounds, formulations, and methods for treating or preventing rosacea
In methods, compounds, and topical formulations for treatment of rosacea incorporating compounds represented by the formulas below:
wherein each of R 1 , R 2 , and R 3 is independently...
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7431916 |
Administration of medicinal dry powders
A method of administering a metered dry powder combined dose of finely divided dry medication powders is disclosed, wherein said method comprises providing a relative motion between a nozzle of a...
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7427639 |
β2-adrenergic receptor agonists
Disclosed are multibinding compounds which are β2 adrenergic receptor agonists and are useful in the treatment and prevention of respiratory diseases such as asthma, bronchitis. They are also...
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7427414 |
Modified release oral dosage form using co-polymer of polyvinyl acetate
Once a day modified release oral dosage form comprising of granules or pellets which are either compressed into tablet or filled inside the capsule, wherein the pellet has a core of active...
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7402698 |
Secondary amino-and cycloamino-cycloalkanol derivatives and methods of their use
The present invention is directed to secondary amino- and cycloamino-cycloalkanol derivatives, compositions containing these derivatives, and methods of their use for the prevention and treatment...
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7399776 |
Polyamine compounds for treating chemokine receptor mediated diseases
This invention relates to a method for treating inflammatory diseases or immune diseases, developmental or degenerative diseases, or tissue injuries. The method includes administering to a subject...
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7384983 |
Inhibitor of monoamine uptake
The present invention provides compounds and methods for the inhibition of monoamine uptake in mammals.
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7375111 |
Compositions for affecting weight loss
Disclosed are compositions for affecting weight loss comprising a first compound and a second compound, where the first compound is an opioid antagonist and the second compound causes increased...
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7368440 |
Methods for the administration of amifostine and related compounds
The present invention provides methods of administering amifostine, WR-1065, or a combination thereof, to patients receiving radiation therapy or chemotherapy in a manner that significantly reduces...
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7332525 |
Method of treatment of prostate cancer and composition for treatment thereof
A method and composition for the treatment of prostate cancer comprises an effective amount of a nonsteroidal antiandrogen and an effective amount of a selective estrogen receptor modulator. The...
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7294649 |
Methamphetamine derivatives and conjugates for immunoassay
Compounds of methamphetamine derivatives having a meta-substituted alkyl linker on the benzene ring and a protective group on the nitrogen of the methamphetamine hapten. Such compounds have the...
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7288571 |
Thyroid receptor ligands and method II
New thyroid receptor ligands are provided which have general formula (I) in which: n is an integer from 0 to 4; R 1 is halogen, trifluoromethyl, or alkyl of 1 to 6 carbons or cycloalkyl of 3 to 7...
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7276518 |
Substituted cyclohexane-1,4-diamine compounds
Substituted cyclohexane-1,4-diamine compounds, methods for production thereof, pharmaceutical compositions comprising these compounds and methods of treatment using these compounds.
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7267949 |
Composition comprising methylphenidate and another drug
A process of treating a subject that is undergoing methylphenidate therapy and concomitant therapy with another drug undergoes or interferes with P 450 metabolism, wherein the methylphenidate is...
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7261889 |
Local anesthetic methods and kits
Methods of reversing local anesthesia are disclosed. The methods comprise administering a local anesthetic and alpha adrenergic receptor agonist to induce local anesthesia followed by reversing...
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7230018 |
Substituted propane-1,3-diamine derivatives and the pharmaceutical use thereof
Substituted propane-1,3-diamine derivatives, methods for producing such derivatives, and medicaments and pharmaceutical compositions containing such derivatives useful for the treatment or...
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7220782 |
Methods to reduce the sensitivity of endothelially-compromised vascular smooth muscle
The present invention discloses materials and methods useful to treat sensitivity of endothelially-compromised vascular smooth muscle. In one embodiment, CLC3 blockers, particularly compounds of...
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7176243 |
CaR receptor as a mediator of migratory cell chemotaxis and/or chemokinesis
This invention relates to methods and compositions for modulating movement of eukaryotic cells with migratory capacity. More specifically, the invention relates to methods and compositions for...
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7169750 |
Methods to mobilize progenitor/stem cells
Methods to elevate progenitor and stem cell counts in animal subjects using compounds which bind to the chemokine receptor CXCR4 are disclosed. Preferred embodiments of such compounds are of the...
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7160857 |
Methods for increasing schwann cell survival
Methods for increasing Schwann cell survival are disclosed. The methods of the invention are useful for the treatment of conditions such as peripheral neuropathies, including diabetic neuropathies.
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7144920 |
Polyamine analogs that activate antizyme frameshifting
Novel polyamines, their synthesis and use in pharmacological, cosmetic or agricultural applications are provided. The polyamines induce antizyme production which in turn down regulates both the...
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7138405 |
Pharmaceutical combinations
Pharmaceutical combinations suitable for treating the lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH) in men are described herein. The combinations contain an...
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7135497 |
Treating neural conditions resulting from spinal cord contusions and other causes
β 2 -agonists, such as clenbuterol and salbutamol can enhance the recovery of locomotive function and/or neuromuscular strength following spinal cord injuries or as a result of degenerative neural...
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7122308 |
Detection of antidepressant induced mania
Methods and kits for assessing the susceptibility of a patient to antidepressant-induced mania are described. The method involves testing a sample from a patient for the presence of the s variant...
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7109198 |
Method for treating obesity
The present invention relates, in general, to obesity, and, in particular, to a method of treating obesity and minimizing metabolic risk factors associated therewith using, for example, zonisamide...
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7105575 |
Methods for the treatment of neuro- disorders using aminothiol compounds
The present invention relates to new uses of S-2-(3-aminopropylamino)ethyl dihydrogen phosphorothioate, (amifostine) and other aminothiol compounds to treat and reverse toxicities caused by...
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7101572 |
Taste masked aqueous liquid pharmaceutical composition
A substantially taste masked liquid pharmaceutical composition containing a pharmaceutically effective amount of an unpleasant tasting drug dissolved or dispersed in an aqueous excipient base, said...
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7094431 |
Method of healing skin wounds in mammals and a composition therefor
This invention pertains to therapeutic antibacterial/antifungal-wound healing compositions comprising a therapeutically effective amount of antibacterial agents and/or antifungal agents and/or...
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RE39221 |
Composition comprising a tramadol material and acetaminophen and its use
This invention relates to a composition comprising a tramadol material and acetaminophen, and its use. As used herein tramadol refers to various forms of tramadol. The compositions are...
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7071194 |
Method for improving respiratory function and inhibiting muscular degeneration
The present invention provides a method for improving respiratory function and inhibiting muscular degeneration (e.g., dystrophy and atrophy). Alternative embodiments of the invention provide a...
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