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8163725 Gel compositions and methods of use  
Improved topical gel compositions for the treatment of skin disorders are described. The gel compositions contain carbomer and methylparaben, and are substantially free of methylparaben crystalline...
8119138 Anti-estrogen and immune modulator combinations for treating breast cancer  
Compositions for treating cancers of mucosal tissues including breast, prostate, ovary, colon are disclosed which include various combinations of new or conventional anti-estrogen compounds,...
8110226 Drug formulations having inert sealed cores  
A drug composition comprising a coated bead is used in the manufacture of immediate release and/or controlled release drug compositions. In a specific embodiment, the bead includes an inert core of...
8106056 Combination preparations comprising bifeprunox and a dopamine agonist  
The present invention relates to a composition containing bifeprunox or its N-oxide, or at least one pharmacologically acceptable salt thereof: and L-DOPA or at least one pharmacologically...
8101666 Methods and compounds for detection of medical disorders  
The invention provides methods for detection of medical disorders, associated with cellular oxidative stress, cell degeneration and/or cell death. The invention further relates to compounds...
8093302 Substituted tetralins as selective estrogen receptor-β agonists  
The present invention relates to novel tetralin ER-β agonist compounds, pharmaceutical compositions thereof, and use of these compounds to treat a ER-β mediated disease such as nocturia, o...
8092831 Antihistamine and decongestant system  
The present invention relates to an oral pharmaceutical formulation that employs: (1) a compressed core containing a decongestant or pharmaceutically acceptable salt thereof; (2) a delayed release...
8093300 Compositions and methods for increasing compliance with therapies using aldehyde dehydrogenase inhibitors and treating alcoholism  
Compositions and methods for treating, preventing, or reducing alcoholism, in particular methods for increasing patient compliance with therapies that require the intake of an ALDH inhibitor...
8084059 Antidepressant dosage form  
The invention pertains to a dosage form 10 and to administering an antidepressant medicament 16 for an extended period of time in a rate-known dose.
8080263 Dispersion for pulmonary delivery of a bioactive agent  
Stabilized dispersions are provided for the delivery of a bioactive agent. The dispersions preferably comprise a plurality of perforated microstructures dispersed in a suspension medium that...
8053427 Brimonidine gel composition  
Improved topical gel compositions, such as those containing brimonidine, for the treatment of skin disorders are described. The gel compositions contain carbomer and methylparaben, and are...
8048882 Pharmaceutical compositions with increased activity  
The invention relates to novel pharmaceutical combinations with improved sodium channel blocking effect. Further, the invention relates to the use of said pharmaceutical combinations in chronic...
8039511 Use of isothiocyanates compounds in treating prostatic diseases and skin cancer  
A method for preventing and treating prostatic diseases and skin cancer using naturally or artificially synthesized isothiocyanates compounds or the derivatives or metabolites thereof.
7993670 Medical pad, and method for making and using  
A germicidal absorptive material for use in surgical packings, wound bandages, sanitary tampons and bed sore prevention and/or treatment uses is provided by a foam-like matrix of hydrophilic...
7973082 Substituted aryloxy alkylamines and their use as monoamine neurotransmitter re-uptake inhibitors  
This invention relates to novel substituted aryloxy alkylamines useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the invention relates to the use of these compounds in a...
7956041 Prophylactic and therapeutic agent of diabetes mellitus  
The invention provides a prophylactic and therapeutic agent of diabetes mellitus, including a combination of an inhibitor of renal glucose reabsorption and a hypoglycemic agent. In accordance with...
7947262 Use of fullerenes for the treatment of mast cell and basophil-mediated disease  
Mast cell (MC) and peripheral blood basophil (PBB)-associated diseases are treated or prevented, or their symptoms are alleviated by the administration of water soluble fullerenes (buckeyballs) to...
7939100 Tulobuterol adhesive patch  
The present invention provides a tulobuterol adhesive patch comprising (a) a support, (b) an acrylic pressure-sensitive adhesive layer containing the percutaneously absorbing drug tulobuterol and...
7927616 Pesticide compositions and methods for their use  
Pesticide compositions and methods for their use are provided. Embodiments of the subject pesticide compositions include a pesticide and an assimilable carbon skeleton energy component. Embodiments...
7915262 Combination preparations comprising SLV308 and a dopamine agonist  
A composition containing SLV308 or its N-oxide, or at least one pharmacologically acceptable salt thereof: and L-DOPA or at least one pharmacologically acceptable salt thereof, for simultaneous,...
7915315 Benzocycloheptyl analogs having sphingosine 1-phosphate receptor activity  
Benzocycloheptyl analogs that have agonist activity at one or more of the S1P receptors are provided. The compounds are sphingosine analogs, which, after phosphorylation, can behave as agonists at...
7906141 Sustained-release, oral pharmaceutical forms of formulation  
A sustained-release, oral pharmaceutical formulation of tramadol comprising a compound formed in situ of tramadol or its salt and a pharmaceutically acceptable acidic substance. The compound formed...
7902177 Treatment of congestion using steroids and adrenergics  
A decongestant composition is provided comprising: (a) a safe and effective amount of an adrenergic compound; (b) a safe and effective amount of a steroid; and (c) a pharmaceutically-acceptable...
7893050 Fasudil in combination therapies for the treatment of pulmonary arterial hypertension  
Preferred embodiments of the present invention are related to novel therapeutic drug combinations and methods for treating and/or preventing pulmonary arterial hypertension and/or stable angina....
7893070 Method of treating parturient placental mammals in order to reduce maternal and/or uterine exhaustion  
The present invention relates to a method of facilitating the birth process of placental mammals, especially to a method of reducing delays in the birth process and, thereby, complications...
7884096 Method of treating mental disorders using of D4 and 5-HT2A antagonists, inverse agonists or partial agonists  
The present invention relates to methods of treating the underlying dysregulation of the emotional functionality of mental disorders (i.e. affect...
7884136 Modified-release formulations of a bupropion salt  
The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of...
7855195 Method of treating mental disorders using D4 and 5-HT2A antagonists, inverse agonists or partial agonists  
The present invention relates to methods of treating of the underlying dysregulation of the emotional functionality of mental disorders (i.e. affect...
7851431 Treatment of actinic keratoses with calcium channel blockers  
The present invention relates to methods and compositions for the treatment and/or prevention of actinic keratoses comprising a calcium channel blocking compound.
7842729 Anti tubercular drug: compositions and methods  
Methods and compositions for treating disease caused by infectious agents, particularly tuberculosis. In particular, methods and compositions comprising substituted ethylene diamines for the...
7838563 Compounds, formulations, and methods for ameliorating telangiectasias  
Methods, compounds, and topical formulations for treatment of telangiectasias are disclosed. The methods comprise topically applying a composition comprising an α-adrenergic receptor agonist to ...
7834062 Aminoalkylphenols, methods of using and making the same  
The present invention relates to Mannich base antimalarial aminoalkylphenol compounds and their use against protozoa of the genus Plasmodium, particularly emerging strains of drug-resistant...
7829595 Rapid dissolution formulation of a calcium receptor-active compound  
The present invention relates to a pharmaceutical composition comprising a therapeutically effective amount of a calcium receptor-active compound and at least one pharmaceutically acceptable...
7825104 Methods and compositions for treating fungal infections  
Phenylboronic acid and water soluble derivatives thereof and related boronic acid compounds are used for treating fungal and bacterial infections.
7825156 Method of treating bipolar depression with a benzamide derivative  
A benzamide derivative, especially amisulpride, is used to prevent or treat bipolar depression of a patient suffering from bipolar disorder I or bipolar disorder II.
7820204 Drug delivery system targeting to estrogen receptor over-expressed cells  
A vector for targeted delivery of drugs into estrogen receptors over-expressed cells is disclosed. The vector of the present invention is mainly about an active targeting delivery carrier which...
7786126 Combination preparations comprising SLV308 and a dopamine agonist  
A composition containing SLV308 or its N-oxide, or at least one pharmacologically acceptable salt thereof: and L-DOPA or at least one pharmacologically acceptable salt thereof, for simultaneous,...
7763660 Inhibitors of Candida albicans  
The invention provides methods for identifying modulators of yeast phenotypic transitions and methods for treating fungal infections with modulators of phenotypic transitions of yeast cells. These...
7754771 Compounds for the treatment of AIDS and other viral diseases  
The present invention provides methods for treating Acquired Immunodeficiency Syndrome (AIDS) and other viral diseases and Human Immunodeficiency Virus (HIV) related infections by administering one...
7737147 Methods and compositions to enhance the efficacy of phosphodiesterase inhibitors  
Methods for treatment of sexual dysfunction in men and women using combinations of phosphodiesterase (PDE) type 5 inhibitors and l-deprenyl or propargylamine compounds are described. Methods of...
7723385 Aniline derivatives as selective androgen receptor modulators  
This invention relates to non-steroidal compounds that are modulators of androgen, glucocorticoid, mineralocorticoid, and progesterone receptors, and also to the methods for the making and use of...
7714023 Treatment or prophylaxis of migraine or headache disorders using citalopram, escitalopram or citalopram metabolites  
Methods for prophylaxis of or treating or preventing migraine or migraine headaches, or other headache disorders include administering to a subject in need of treatment a therapeutically effective...
7709530 Rodenticidal composition in the form of vegetable paste  
The present invention relates to a rodenticidal composition in the form of fresh paste for enticing mice and rats wherein the flour used is mainly of a vegetable origin and the fatty matter...
7705054 Method of preventing and/or treating oxidant injury in neurodegenerative and oxidative diseases  
A method of treating and/or preventing oxidative damage, comprising administering an effective IsoK/NeuroK adduct formation suppressing amount of a phenolic amine compound and/or pyridoxamine or...
7700657 Vitamin D analogs  
Novel vitamin D analogs, markedly active in the fields of cell proliferation and differentiation, are selected from among...
7700626 Compositions containing opioid antagonists  
Compositions containing opioid antagonists, particularly alvimopan and its active metabolite, with improved solubility and bioavailability for oral or parenteral administration, injectable dosage...
7678779 Methods for the administration of amifostine and related compounds  
The present invention provides methods of administering amifostine, WR-1065, or a combination thereof, to patients receiving radiation therapy or chemotherapy in a manner that significantly reduces...
7671087 Amines that inhibit a mammalian anandamide transporter, and methods of use thereof  
One aspect of the present invention relates to amines. A second aspect of the present invention relates to the use of the amines as inhibitors of a mammalian anandamide transporter. The compounds...
7671094 Bupropion hydrobromide and therapeutic applications  
Bupropion hydrobromide formulations as well as their use for the treatment of conditions is described.
RE41148 Oral pulsed dose drug delivery system  
A multiple pulsed dose drug delivery system for pharmaceutically active amphetamine salts, comprising an immediate-release component and an enteric delayed-release component wherein (1) the enteric...