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6221917 |
Pharmaceutical composition containing bupropion hydrochloride and a stabilizer
Novel, stable formulations of bupropion hydrochloride are provided which will maintain at least 80% of initial bupropion hydrochloride potency after one year. Methods of inhibiting degradation of...
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6211244 |
Calcium receptor-active compounds
The present invention features compounds able to modulate one or more activities of an inorganic ion receptor and methods for treating diseases or disorders by modulating inorganic ion receptor...
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6211171 |
Use of antidepressants for local analgesia
When administered locally, tricyclic, second generation and third generation antidepressants, such as amitriptyline and desipramine, have been shown to produce analgesia in a subject having a site...
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6207674 |
Dextromethorphan and oxidase inhibitor for weaning patients from narcotics and anti-depressants
Patients can be helped to break free of addictive or habit-forming narcotics and anti-depressants, by treatment using two drugs. One drug is dextromethorphan (DM), which has been used for decades...
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6204245 |
Treatment of narcolepsy with immunosuppressants
The invention provides compositions and methods for treatment of narcolepsy or isolated cataplexy. Such methods entail administering a therapeutically effective regime of at least one...
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6197827 |
Nicotine addiction treatment
The present invention encompasses methods of treating patients for tobacco addiction and nicotine addiction, for palliating the effects of nicotine withdrawal, for providing or facilitating the...
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6194399 |
Aryldiamine derivatives useful as antibacterial agents
Disclosed are pharmaceutical compositions and formulations comprising the compound: ##STR1## wherein: (a) R 1 , R 2 , R 3 , and R 4 are independently selected from the group consisting of...
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6191171 |
Para-aminomethylaryl carboxamide derivatives
para-Aminomethylaryl carboxamides of Formula I are antagonists of VLA-4 and/or α 4 β 7 , and as such are useful in the inhibition or prevention of cell adhesion and cell-adhesion mediated...
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6191133 |
Treatment of depression and pharmaceutical preparations therefor
It has been found that the treatment of depression using known serotonin reuptake inhibitors (SRIs) and noradrenaline reuptake inhibitors (NRIs) may be improved by the administration therewith of...
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6184222 |
Treatment of conduct disorder
Norepinephrine reuptake inhibitors are used to treat conduct disorder.
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6172091 |
1,2-Disubstituted cyclopropanes
Compounds of Formula I ##STR1## wherein the substituents are as described in the specification or pharmaceutically acceptable salts or stereochemically isomeric forms thereof, useful for treating...
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6166081 |
Methods and apparatus for treatment of Parkinson's disease
A pharmaceutical composition for treatment of Parkinson's disease comprising a compound of levodopa dissolved in a non-degradative solvent which allows transdermal administrtion of levodopa. The...
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6159971 |
Combination of a 5-HT reuptake inhibitor and a H5-HT1B anatagonist or partial agonist
The invention relates to a combination of a first component (a) which is a 5-HT reuptake inhibitor and a second component (b) which is selective h5-HT 1B antagonist or partial agonist having the...
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6150420 |
Method for enhanced brain delivery of bupropion
This invention provides to a method for enhancement of delivery of bupropion by administration via the nasal route, and methods of treatment comprising intranasal administration of bupropion. The...
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6147072 |
Combination therapy for treatment of psychoses
The invention relates to a method of treating psychosis, acute mania, mild anxiety states or depression in combination with psychotic episodes by administering to a patient a combination of an...
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6139879 |
Fungicidal and bactericidal compositions for plants containing compounds in the form of heavy metal
The present invention relates to heavy metal chelate compositions, which are used as fungicides and bactericides, and methods of using the compositions. In particular, the present invention relates...
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6114382 |
Methods for treating inflammatory bowel disease
The present invention provides novel compositions and methods relating to the treatment of Inflammatory Bowel Disease ("IBD"), most notably, Ulcerative Colitis, Crohn's Disease, Colitis and...
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6110973 |
Methods for treating obesity and weight gain using optically pure (-)-bupropion
Methods are disclosed utilizing the optically pure (-)-isomer of bupropion, which is a potent drug for treating obesity and weight gain.
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6096738 |
Method for treatment of headache
A method for preventing and treating headache pain comprising administering a tricyclic antidepressant compound locally to the nasal mucosa to a patient suffering from headaches.
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6087346 |
Sigma receptor ligands and the use thereof
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6083993 |
Method for treating bronchospasm using optically pure R(-) albuterol
The optically pure R(-) isomer of albuterol, which is substantially free of the S(+) isomer, is a potent bronchodilator for relieving the symptoms associated with asthma in individuals. A method is...
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6075056 |
Antifungal/steroid topical compositions
Stable topical formulations comprising an antifungal agent and an antiinflammatory steroid are disclosed, useful for treating fungal diseases and their related inflammation.
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6075023 |
Method for combatting fish mycoses and one-celled ectoparasites
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6071918 |
Combination of an opioid antagonist and a selective serotonin reuptake inhibitor for treatment of alcoholism and alcohol dependence
The invention relates to a method of treating alcoholism and alcohol dependence in a mammal comprising administering to the mammal a therapeutically effective amount of a synergistic combination...
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6066672 |
Amino compounds and angiotensin IV receptor agonists
The present invention provides an amino compound represented by Formula: ##STR1## wherein X is CH 2 NH or CONH, Y is CH 2 NH or CONH with the proviso that X and Y are not CONH at the same time; Z...
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6066675 |
Method for treatment of retinal diseases
Methods for the stimulation of growth factor expression and for treatment of retinal diseases with alpha- and beta-adrenergic agonists are disclosed.
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6063400 |
Targeted liposomal constructs for diagnostic and therapeutic uses
This invention provides a liposomal construct for delivering a diagnostic or therapeutic agent to a mammal comprising a liposomal carrier, a diagnostic or therapeutic agent entrapped within or...
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6051605 |
Method of treating psychosis and schizophrenia
This invention relates to compounds that are antagonists of dopamine D4 receptors, and to methods of treating psychosis and schizophrenia using a compound that is an antagonist of dopamine D4...
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6048882 |
Prophylactic and therapeutic agent for hepatic diseases
Hepatic diseases can be prevented or treated by administering an isoprenylamine derivative represented by the general formula (II) ##STR1## [wherein n represents an integer of 4-12, m represents an...
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6043285 |
Use of p-aminophenol derivatives for the preparation of pharmaceutical compositions useful in the treatment of neurodegenerative diseases
A therapeutic method comprising treating a patient suffering from a neurodegenerative disease with a therapeutically effective quantity of a p-aminophenol derivative.
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6034091 |
Method for treating emotional or mental illness and emotional or mental illness concomitant with seizures
Disclosed herein is a method for treating depression associated with alcoholism in a patient comprising administering to the patient a pharmacologically effective dose of an opioid antagonist, and...
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6031003 |
Calcium receptor-active molecules
The present invention relates to the different roles inorganic ion receptors have in cellular and body processes. The present invention features: (1) molecules which can modulate one or more...
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6028070 |
Treatment of oppositional defiant disorder
Norepinephrine reuptake inhibitors are used to treat oppositional defiant disorder.
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6015837 |
Method for treating scoliosis with β2-adrenoceptor agonists
A method of treating scoliosis by adminstering β 2 adrenergic agonists in amounts sufficient to correct the condition.
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6011066 |
Method for treating septic shock
A method for the treating septic shock in a patient comprises administering to the patient a therapeutically-effective amount of a composition comprising a compound having the formula (I): ##STR1##...
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6011069 |
Multidrug resistance inhibitors
There is disclosed a multidrug resistance inhibitor for overcoming a multidrug resistance of cancer, or an agent for enhancing the activity of anti-cancer agents, which comprises as an active...
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6011054 |
Method for treating depression, obsessive compulsive disorder, and anxiety with N--acetyl serotonin
The present invention relates to a method of treatment of depression in a human being identified as having depression. This method comprises the administration of a therapeutically effective...
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5994409 |
Methods for treatment of neuro--and nephro--disorders and therapeutic toxicities using aminothiol compounds
The present invention relates to new uses of S-2-(3-aminopropylamino)ethyl dihydrogen phosphorothioate, (amifostine) and other aminothiol compounds to treat and reverse toxicities caused by...
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5990151 |
Optically active substituted phenylalkylamine derivatives
The present invention relates to an optically active, substituted phenylalkylamine derivative represented by Formula [1]: ##STR1## wherein A is a substituted or non-substituted phenyl or thienyl; X...
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5990175 |
Prevention of migraine
A method of preventing migraine headaches in humans by the administration of the compound of the formula I ##STR1## or a pharmaceutically acceptable acid addition salt thereof in a non-toxic,...
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5968553 |
Pharmaceutical composition containing bupropion hydrochloride and an inorganic acid stabilizer
Novel, stable formulations of bupropion hydrochloride are provided which will maintain at least 80% of initial bupropion hydrochloride potency after one year. Methods of inhibiting degradation of...
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5962463 |
Methods of stimulating non-amyloidogenic processing of the amyloid precursor protein
Stimulating non-amyloidogenic processing by the activation of cell surface serotonin receptors linked to phospholipase and protein kinase C is described. Activation of the cell surface serotonin...
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5955508 |
Method for the enhancement of lymphocyte activity against opportunistic microbial pathogens
The invention relates to the treatment of an immunocompromised human, e.g., an AIDS or HIV positive patient, for the enhancement of lymphocyte activity against opportunistic microbial pathogens or...
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5942544 |
α-branched anilines, toluenes, and analogs thereof as factor Xa inhibitors
The present application describes m-amidino phenyl analogs of formula I: ##STR1## wherein D can be amidino and E can be phenyl, which are useful as inhibitors of factor Xa.
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5939076 |
Composition and method for treating or alleviating migraine headaches
A method of preventing or alleviating a migraine headache in a patient subject to migraine headaches comprises administering to the patient daily, for an effective period of time, a daily effective...
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5925370 |
Biorepellent matrix coating
A biorepellent matrix structure comprises a resin and first and second micapsules suspended in the resin. The first and second microcapsules each includes a first shell and a second shell,...
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5925332 |
Radioimaging and radiochemotherapy phenolic thioether amines and acyl derivatives thereof for use in diagnosing and treating pigmentation disorders
Compounds useful in radioimaging and radiochemotherapy as it particularly relates to the treatment and location of malignant melanomas and other pigmenting disorders, as well as novel acyl...
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5922744 |
Ethane-1-2-diamine derivatives and tachykinin antagonists
The present invention provides a compound of formula: ##STR1## wherein R, R 1 , R 2 , R 3 , R 4 , R 5 , R 6a and R 6b are defined herein or a pharmaceutically acceptable salt thereof, a process...
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5919827 |
Method for treating asthma using optically pure R(-) salmeterol
The optically pure R(-) isomer of salmeterol, which is substantially free of the S(+) isomer, is a potent bronchodilator for relieving the symptoms associated with asthma in individuals. A method...
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5916923 |
Venlafaxine for the treatment of generalized anxiety disorder
This invention provides a method of treating obesity, generalized anxiety disorder, post-traumatic stress disorder, late luteal phase disphoric disorder (premenstrual syndrome), attention deficit...
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