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6608041 |
Analgesics combined with naturally-occurring chondroprotective agents
Provided herein are medicinal compositions of matter that comprise a chondroprotective component and an analgesic component, wherein the chondroprotective component is naturally occurring in a...
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6605300 |
Oral pulsed dose drug delivery system
A multiple pulsed dose drug delivery system for pharmaceutically active amphetamine salts, comprising an immediate-release component and an enteric delayed-release component wherein (1) the enteric...
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6586476 |
Methods for the treatment of nephro-disorders using aminothiol compounds
The present invention relates to new uses of S-2-(3-aminopropylamino)ethyl dihydrogen phosphorothioate, (amifostine) and other aminothiol compounds to treat and reverse toxicities caused by...
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6582683 |
Dermal barrier composition
Disclosed is a dermal barrier composition which contains a hydrophilic polymer emulsion and a hydrophobic polymer emulsion. The dermal barrier composition is moisture activated, and remains inert...
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6579899 |
Composition for treatment of stress
A method of treating stress in a patient showing stress related symptoms is disclosed, where the method comprises administering to the patient an effective amount of a serotoninergic drug or...
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6569903 |
Ophthalmic compositions
Ophthalmic compositions having negligible side effects on the heart can be obtained by using as the active ingredient an adrenergic β receptor agonist having a high selectivity toward adrenergic...
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RE38115 |
Dextromethorphan and an oxidase inhibitor for treating intractable conditions
Methods are disclosed for increasing the effectiveness of dextromethorphan in treating chronic or intractable pain, for treating tinnitus and for treating sexual dysfunction comprising...
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6548522 |
Method for treating conditions related to the glutamate receptor using carboxylic acid amide derivatives
The present invention is concerned with the use of carbonylamino derivatives of the formula wherein R signifies lower alkyl, lower alkenyl, lower alkinyl, cycloalkyl, lower alkoxy or CF 3 ; R 1 ...
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6545057 |
Tricyclic antidepressants and their analogues as long-acting local anesthetics and analgesics
Methods and compositions of tricyclic antidepressants for inducing local long-lasting anesthesia and analgesia are provided. The methods and compositions are useful for alleviating acute and...
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6541523 |
Methods for treating or preventing fibromyalgia using very low doses of cyclobenzaprine
The present invention relates to methods and compositions comprising a very low dose of cyclobenzaprine or metabolite thereof for preventing and treating sleep disturbances and illnesses manifested...
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6538035 |
Use of tolterodine to treat asthma
The present invention is a method of treating an mammal selected from the group consisting of humans and horses who has asthma, COPD or allergic rhinitis and is in need of such treatment by...
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6518314 |
Pharmaceutical agents that impede the initiation and progression of primary and secondary DMS disruptions
Compositions comprising a pharmaceutically effective amount of a compound that impedes disruption of intact dense microspheres (DMS) by acting on DMS either to prevent disruption, or if disrupted,...
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6514934 |
Imidazoline α-adrenergic receptor antagonist compounds in combination with nitric oxide donors, compositions and methods of use
The present invention is directed to nitrosated or nitrosylated α-adrenergic receptor antagonists, compositions comprising α-adrenergic receptor antagonists that are optionally substituted with...
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6512011 |
Bupropion to treat herpes viral diseases
Methods are disclosed for the treatment of a herpes viral infection in a human or animal subject by administering bupropion or a physiologically acceptable salt, solvate or enantiomer thereof. Most...
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6479063 |
Therapeutic uses of hormonal manipulation using combinations of various agents to treat atherosclerosis
A method of decreasing atherosclerosis and its complications involving administering to a human or animal various combinations of medications with Finasteride, Bicalutamide, Flutamide and Nilutamide.
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6468973 |
Method in the treatment of schizophrenia
The invention relates to the use of a composition comprising at least one substance within the group GnRH-analogues for producing a drug for treatment of schizophrenia. The invention makes it...
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6465522 |
Anthraquinone anticancer drugs
A molecule of formula (I); wherein: X is a halogen, or a substituted sulfonate group; m=1-5; n=1-5; R 1 , R 2 =H, C1-4 lower alkyl or C1-4 lower alkyl chain having additional functionality; and...
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6462094 |
Decongestant/expectorant compositions
Compositions consisting essentially of phenylephrine tannate and guaifenesin which are effective when administered orally for the symptomatic relief of cough associated with respiratory tract...
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6455590 |
Deprenyl compounds for treatment of glaucoma
Methods and kits for treament of glaucoma are disclosed. In general, the methods of the invention include administering a therapeutically effective amount of a deprenyl compound to a subject such...
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6451860 |
Methods for treating depression and other disorders using optically pure (−)-bupropion
Methods are disclosed utilizing the optically pure (−)-isomer of bupropion, which is a potent drug for treating depression, Parkinson's disease, obesity, weight gain and other disorders.
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6444708 |
Treatment using venlafaxine
This invention provides a method of treating obesity, generalized anxiety disorder, post-traumatic stress disorder, late luteal phase disphoric disorder (premenstrual syndrome), attention deficit...
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6441047 |
Combination therapy for treating glaucoma
Methods for treating persons with glaucoma or ocular hypertension with glutamate antagonists and IOP-lowering compounds are disclosed.
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6441038 |
Treatment of fatigue, head injury and stroke
A method of treatment of disorders of neurological origin and drug formulations for use in the method are disclosed. These conditions comprise fatigue and associated syndromes of pain, weakness and...
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6441048 |
Methods of treating affective disorders using derivatives of (-)-venlafaxine
Methods of preparing, and compositions comprising, derivatives of (−)-venlafaxine are disclosed. Also disclosed are methods of treating and preventing diseases and disorders including, but not...
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6436437 |
Covalent polar lipid conjugates with neurologically active compounds for targeting
This invention herein describes a method of facilitating the entry of drugs into cells and tissues at physiologically protected sites at pharmicokinetically useful levels and also a method of...
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6436938 |
Combination treatment for depression
The present invention relates to a method of treating depression, especially refractory depression, in a mammal, including a human, by administering to the mammal a sigma receptor ligand in...
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6426096 |
Anorexigenic composition
A method of treating carbohydrate craving in a human patient comprises administering to the patient an anorexigenic composition comprising a compound which elevates serotonin levels in the brain of...
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6395762 |
Phenyl amino squarate and thiadiazole dioxide beta-3 adrenergic receptor agonists
This invention provides compounds of Formula I having the structure wherein, R 1 , R 2 , and X are as defined hereinbefore, or a pharmaceutically acceptable salt thereof, which are useful in...
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6387907 |
Use of serotonin agonists to alleviate disordered breathing episodes in a mammal
The invention includes compositions for alleviating or preventing a disordered breathing episode. The composition of the invention comprises a serotonin re-uptake inhibitor, a TRH agonist and an...
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6369113 |
Method for treating depression using optically pure (−)-bupropion
Methods and compositions are disclosed utilizing the optically pure (−)-isomer of bupropion, which is a potent drug for treating depression.
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6369051 |
Combinations of SSRI and estrogenic agents
This invention comprises methods of depression, anxiety, generalized anxiety disorder (GAD), hot flush, post partum depression, premenstrual syndrome, obesity, obsessive compulsive disorder,...
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6362371 |
β2- adrenergic receptor agonists
The present invention is directed to multibinding compounds which are β2 adrenergic receptor agonists and are therefore useful in the treatment and prevention of respiratory diseases such asthma,...
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6358944 |
Methods and compositions for treating generalized anxiety disorder
The present invention relates to methods and compositions comprising a very low dose of cyclobenzaprine or metabolite thereof for preventing and treating Generalized Anxiety Disorder. The present...
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6355685 |
Method of treating anxiety disorders
A compound of formula I or a pharmaceutically acceptable salt thereof in which R 1 and R 2 are independently H or methyl (for example...
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6342496 |
Bupropion metabolites and methods of use
Methods are disclosed which utilize metabolites of bupropion for treating disorders ameliorated by inhibition of neuronal monoamine reuptake. Such disorders include, cerebral function disorders,...
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6342533 |
Derivatives of (−)-venlafaxine and methods of preparing and using the same
Methods of preparing, and compositions comprising, derivatives of (−)-venlafaxine are disclosed. Also disclosed are methods of treating and preventing diseases and disorders including, but not...
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6337328 |
Bupropion metabolites and methods of use
Methods are disclosed which utilize metabolites of bupropion for treating sexual dysfunction.
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6335368 |
Use of alverine for reducing wrinkles
The present invention relates to the use of at least an effective amount of Alverine or a salt thereof in a composition or for the preparation of a composition, the Alverine or a salt thereof or...
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6333332 |
Stabilized pharmaceutical compositions containing bupropion hydrochloride
This invention is directed to stabilized pharmaceutical preparations containing bupropion hydrochloride. The preferred stabilizers comprise salts of organic bases including those selected from the...
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6331555 |
Treatment of platelet derived growth factor related disorders such as cancers
The present invention concerns compounds which can inhibit platelet derived growth factor receptor (PDGF-R) activity, preferably such compounds also inhibit the activity other members of the PDGF-R...
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6329399 |
Antifungal amine derivatives and processing for producing the same
Novel amine derivatives having an excellent antimycotic effect represented by general formula (1) below and salts thereof are provided. ##STR1## [in the formula (1, R 1 represents a C 1 -5 alkyl...
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6319953 |
Treatment of depression and anxiety with fluoxetine and an NK-1 receptor antagonist
The present invention relates to the treatment or prevention of depression and/or anxiety by the administration of a combination of a specific class of NK-1 receptor antagonists and fluoxetine.
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6316469 |
Use of selective serotonin reuptake inhibitors for treatment of chest pain of non-cardiac origin and gastro-esophageal reflux disease
Selective serotonin reuptake inhibitors useful in the treatment of non-cardiac chest pain or the treatment of symptoms of gastro-esophageal reflux disease.
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6312716 |
Patch and method for transdermal delivery of bupropion base
The invention includes a patch and method for transdermal delivery of bupropion base. In the method of this invention, a patient is administered a bupropion base in an amount effective to alleviate...
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6297290 |
Composition containing a nerve fiber reactivity modulating compound
The present invention relates to a novel aqueous composition based on a compound modulating the reactivity of nerve fibers. It relates more particularly to a pharmaceutical composition for topical...
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6294580 |
Substituted 4-hydroxy-phenylalcanoic acid derivatives with agonist activity to PPAR-gamma
A compound having formula (I), wherein A is selected from the group consisting of: (i) phenyl, wherein said phenyl is optionally substituted by one or more halogen atoms, C 1 -6 alkyl, C 1 -3...
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6291532 |
Use of N-aryl-2-hydroxyalkylamides for stimulating or inducing hair growth and/or arresting hair loss
Methods and compositions for induction or stimulation of hair growth and retardation of hair loss are provided. Preferably, these compounds will include a perhalogenated alkyl radical having 1 to 4...
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6280763 |
Apparatus and method for transdermal delivery of bupropion
The invention includes an apparatus and method for transdermal delivery of bupropion base. In the method of this invention, patient is administered parenterally a bupropion base in an amount...
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6277887 |
Methods for treating Parkinson's disease using optically pure (-)-bupropion
Methods and compositions are disclosed utilizing the optically pure (-)-isomer of bupropion, which is a potent drug for treating, Parkinson's disease.
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6221887 |
Treatment of inflammatory disorders with NMDA antagonists and sodium channel antagonists
The invention relates to the use of certain pharmaceutical compounds as anti-inflammatory agents.
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