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7411093 Aminocycloalkanes as DPP-IV inhibitors  
The present invention relates to compounds of formula (I) wherein R 1 is as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for...
7396860 Use of rasagiline with or without riluzole to treat amyotrophic lateral sclerosis  
The subject invention provides a method for treating amyotrophic lateral sclerosis (ALS) in a subject in need of such treatment comprising administering to the subject R(+)-N-propargyl-1-aminoindan...
7326733 Methods for increasing bone density  
Methods and compounds for remodeling bone and treating osteopenic conditions are described. Methods and compounds for increasing bone mineral density by decreasing serotonin levels in osteoblasts...
7307071 RAF-MEK-ERK pathway inhibitors to treat cancer  
Materials and methods for treating certain cancers are described, preferably cancers that result from the up-regulation of the RAF-MEK-ERK pathway, and more preferably chronic myelogenous leukemia,...
7306811 Fungicide composition based on halosulphone in particular for packaging  
A packaging sheet comprising a mixture of compound A where R 1 may be an alkyl, alkoxy or alkylene radical having 1 to 6 carbon atoms; X 1 and X 2 , identical or...
7201854 Active compound combinations for protecting animal hides and leather  
The present application relates to the use of active compound combinations containing phenolic active compounds and fungicidal active compounds for preserving animal hides and leather.
7105502 Nitric oxide-releasing imidate and thioimidate diazeniumdiolates  
The invention provides NO- or NO − -releasing imidate; and thioimidate, diazeniumdiolates, in which the N 2 O 2 − functional group is bonded to a carbon atom. The imidate and thioimidate...
7071194 Method for improving respiratory function and inhibiting muscular degeneration  
The present invention provides a method for improving respiratory function and inhibiting muscular degeneration (e.g., dystrophy and atrophy). Alternative embodiments of the invention provide a...
6992106 Anti-tumor composition  
The present invention provides composition having as active ingredients a stilbene derivative and a platinum coordination compound which is highly efficacious and highly safe for treating tumors,...
6974839 Method of delaying ejaculation  
The invention provides a method of delaying ejaculation. The method comprises administering an effective amount of a tramadol material to a human male prior to sexual intercourse. The method is...
6956060 Use of R-enantiomer of N-propargyl-1-aminoindan, salts, and compositions thereof  
The subject invention provides R(+)-N-propargyl-1-aminoindan and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions containing same. The subject invention also...
6949530 Nitric oxide-releasing amidine diazeniumdiolates, compositions and uses thereof and method of making same  
The present invention relates to nitric oxide-releasing amidine diazeniumdiolates, compositions comprising same, methods of using same, and a method for preparing same from imidate...
6943195 Cycloalkenone derivative  
(−)-3-[3-[(1R,2R,4S)-bicyclo[2.2.1]hept-2-yloxy]-4-methoxy anilino]-2-methyl-2-cyclopenten-1-one, or its hydrate or solvate, or a pharmaceutical composition containing the same.
6927223 Use of serotonin agents for adjunct therapy in the treatment of cancer  
The invention provides a method for the treatment of cancer comprising administering a serotonin agent. Also provided is a method for the treatment of cachexia comprising administering a serotonin...
6919310 Method of treating the syndrome of coronary heart disease risk factors in humans  
The invention provides an improved method of treating a human suffering from one or more conditions included within the Coronary Heart Disease Risk Factor (CHDRF) syndrome. The method includes...
6908944 Use of 6-dimethylaminomethyl-1-phenyl-cyclohexane compounds for treatment of urinary incontinence  
A pharmaceutical composition comprising a pharmaceutically acceptable excipient and a compound of formula I: It has been surprisingly discovered that the pharmaceutical composition of the...
6897241 Preparation of topical regional compositions for the relief of pain  
A method is presented for the preparation of topically applied compositions used for the treatment of regional pain, especially sympathetically mediated pain. NMDA receptor antagonists, such as...
6887905 Treatment of depression or generalized anxiety disorder  
A pharmaceutical composition for treating a disorder that is treated by modulation of serotonergic neurotransmission comprising administering...
6858652 Sertraline hydrochloride polymorphs, processes for preparing them, compositions containing them and methods of using them  
The present invention is directed to novel polymorphic Forms XI, XII, XIII, XIV, XV and XVI of sertraline hydrochloride, to processes for preparing them, methods of using them to treat disease,...
6855735 Ketamine treatment of restless legs syndrome  
The present invention is directed to a method for treating symptoms associated with Restless Legs Syndrome (RLS). The method includes administering to a warm-blooded animal in need of such...
6683115 β2-adrenergic receptor agonists  
Disclosed are multibinding compounds which are β2 adrenergic receptor agonists and are useful in the treatment and prevention of respiratory diseases such as asthma, bronchitis. They are also...
6667343 Siloxane dyes, compositions containing them and uses thereof  
Linear or cyclic diorganosiloxane compounds that include at least one nitroaniline function are disclosed; the compounds may be used as organic dyes in cosmetic compositions suitable for dyeing...
6667329 Agents with antidepressant action, containing pramipexol and second antidepressant  
The present invention relates to the use of 2-amino-4,5,6,7-tetrahydro-6-propylamino-benzothiazole (pramipexole), the (+)- or (−)-enantiomer thereof or one of the pharmacologically acceptable...
6630514 Use of R-enantiomer of N-propargyl-1-aminoindan, salts, and compositions thereof  
The subject invention provides R(+)-N-propargyl-1-aminoindan and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions containing same. The subject invention also...
6552088 Biphenyl derivatives  
Biphenyl substituted amides with activity as antagonists of the neurokinin 1 (NK-1, substance P) receptor.
6548084 Controlled release compositions  
A controlled release or delayed release formulation contains a selective serotonin reuptake inhibitor (SSRI) such as paroxetine.
6531512 Method of treating cancer in patients having a deficiency in p53 tumor suppressor gene  
A method of treating cancer in a patient deficient in p53 tumor suppression gene is described herein by administering to a patient a therapeutically effective amount if a polyamine such as DENSPM...
6492427 Methods for treating multiple sclerosis  
Methods for increasing oligodendrocyte survival are disclosed. The methods of the invention are useful for the treatment of Multiple Sclerosis.
6437000 Controlled release oral dosage for suitable for oral administration  
The present invention is directed to a pharmaceutical composition, preferably in the form of a tablet comprising a therapeutically effective amount of a medicament in a carrier comprising a water...
6423698 Combination therapy for the prophylaxis and/or treatment of benign prostatic hyperplasia  
A combination therapy for the prophylaxis and/or treatment of benign prostatic hyperplasia in susceptible warm-blooded animals which comprises administering a combination of two or more compounds...
6399608 Combination of a GABA-A α 2/3 agonist and a selective serotonin reuptake inhibitor  
A pharmaceutical product comprising an SSRI and a non-sedating anxiolytic compound, which is a modulator of the benzodiazepine binding site of the human GABA A receptor, having a binding affinity...
6387957 Preparation of topical regional compositions for the relief of pain  
Methods are presented whereby regional pain relief is achieved through the periodic topical administration of compositions comprising NMDA receptor antagonists, by applying said compositions to the...
6387956 Methods of treating obsessive-compulsive spectrum disorders  
A method of treating an obsessive-compulsive spectrum disorder comprises the step of administering an effective amount of tramadol to an individual.
6380200 Combination of aldose reductase inhibitors and selective serotonin reuptake inhibitors for the treatment of diabetic complications  
This invention is directed to methods, pharmaceutical compositions and kits comprising an aldose reductase inhibitor (ARI), a prodrug thereof or a pharmaceutically acceptable salt of said ARI or...
6358944 Methods and compositions for treating generalized anxiety disorder  
The present invention relates to methods and compositions comprising a very low dose of cyclobenzaprine or metabolite thereof for preventing and treating Generalized Anxiety Disorder. The present...
6329399 Antifungal amine derivatives and processing for producing the same  
Novel amine derivatives having an excellent antimycotic effect represented by general formula (1) below and salts thereof are provided. ##STR1## [in the formula (1, R 1 represents a C 1 -5 alkyl...
6329362 Cinnamic acid derivatives  
Compounds of formula (1) are described: ##STR1## wherein L 1 is a covalent bond or a linker atom or group; R is a carboxylic acid (--CO 2 H) or a derivative threof; R 6 and R 7 which...
6326402 Methods for treating viral infections using a compound capable of inhibiting microtubules  
The present invention is directed to a method for inhibiting viral replication and treating viral infections by administering a pharmaceutically effective amount of a compound capable of binding a...
6316504 Use of R-enantiomer of N-propargyl-1-aminoindan, salts, and compositions thereof  
The subject invention provides R(+)-N-propargyl-1-aminoindan and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions containing the same. The subject invention also...
6277886 Pharmaceutical compositions comprising S-(-)-N-propargyl-1-aminoindan  
Pharmaceutical compositions for the treatment of a neurological disorder of neurotrauma or for improving memory in a patient comprising a therapeutically effective amount of...
6274570 Pesticidal compositions  
A liquid pesticidal composition, which is substantially free of water, comprising a hydrophobic pesticide or mixture of pesticides dissolved in an organic solvent and comprising as surfactants (a)...
6255329 Combined use of pramipexole and sertraline for the treatment of depression  
The present invention relates to the use of 2-amino-4,5,6,7-tetrahydro-6-n-propylamino-benzothiazole (pramipexole), the (+)- or (-)- enantiomer thereof, or one of the pharmacologically acceptable...
6248789 Administration of ketamine to manage pain and to reduce drug dependency  
6232348 Hydroxymethyl derivatives of 2-amino-1,2,3,4-tetrahydronaphthalene as cardiovascular agent  
Compounds of formula (I) ##STR1## wherein R, R', R", R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , X, Y, m, n, and p have the meanings reported in the description; and their pharmaceutically acceptable salts...
6197830 Method for achieving relief from sympathetically mediated pain  
A method is presented whereby sympathetically mediated pain relief is achieved through the periodic topical administration of compositions comprising tricyclic antipressants mixed with one or more...
6194399 Aryldiamine derivatives useful as antibacterial agents  
Disclosed are pharmaceutical compositions and formulations comprising the compound: ##STR1## wherein: (a) R 1 , R 2 , R 3 , and R 4 are independently selected from the group consisting of...
6184236 Method of treating a neurodegenerative disease by administering an aryl-cyclohexylamine derivative  
The present invention provides a method of treatment of a disease associated with neurodegeneration by administering a therapeutically effective amount of a compound of the general formula ##STR1##...
6177473 Benzamidine derivatives substituted by cyclic amino acid and cyclic hydroxy acid derivatives and their use as anti-coagulants  
This invention is directed to benzamidine derivatives substituted by cyclic amino acid and cyclic hydroxy acid derivatives which are useful as anti-coagulants. This invention is also directed to...
6136863 Antifungal agents  
This invention relates to compounds represented by the following formula (1): ##STR1## wherein R 1 represents a substituted or unsubstituted phenyl group, R 2 represents a substituted or...
6133281 NMDA receptor blockers in the therapy of urogenital disease  
Methods are presented for the treatment of benign prostatic hyperplasia. The methods provide for administration to a person at least one compound identified generically as antagonists of...
Matches 1 - 50 out of 179 1 2 3 4 >