|
Match
|
Document |
Document Title |
|
|
6114344 |
Long-acting local anesthetics
The subject invention concerns novel compounds that are useful as long-acting local anesthetics. The compounds are N-acyl derivatives of the compound known as tetracaine.
|
|
|
6114382 |
Methods for treating inflammatory bowel disease
The present invention provides novel compositions and methods relating to the treatment of Inflammatory Bowel Disease ("IBD"), most notably, Ulcerative Colitis, Crohn's Disease, Colitis and...
|
|
|
6114394 |
Polyamine derivatives as radioprotective agents
The present invention relates to polyamine derivatives of the formula RHN-(CH 2 ) m -NH-(CH 2 ) n -NHR wherein m is an integer from 2 to 4, n is an integer from 3 to 10 and R is C 2 -C 6 alkyl...
|
|
|
6103768 |
Fatty acid based compositions and methods for the control of plant infections and pests
The invention described here concerns the unique utility of fatty acids and their derivatives to eradicate existing fungal and bacterial infections in plants. Also, described herein are combination...
|
|
|
6090856 |
Remedies for frequent urination and urinary incontinence
The object of this invention is to provide a novel medicinal use for tramadol the safety, among other properties, of which has already been established. This invention is directed to a therapeutic...
|
|
|
6075031 |
Use of creatine analogues and creatine kinase modulators for the prevention and treatment of glucose metabolic disorders
The present invention relates to the use of creatine compounds including cyclocreatine and creatine phosphate for treating or preventing a metabolic disorder consisting of hyperglycemia, insulin...
|
|
|
6075044 |
Heterocyclic derivatives as inhibitors of purine salvage phosphoribosyltransferases
The use of certain heterocyclic derivatives for treating parasitic protozoa infections in mammals, in particular bovine trichomoniasis and giardiasis, is disclosed.
|
|
|
6069176 |
Phenylethanolamine compounds useful as β 3 agonists, process for producing the same, and intermediates in the production of the same
The present invention relates to phenylethanolamine compounds represented by general formula [I]: ##STR1## (where R 1 represents hydrogen or halogen; R 2 represents hydrogen, hydroxy, lower...
|
|
|
6054488 |
Medicinal aerosol formulations of formoterol
A pharmaceutical suspension formulation suitable for aerosol administration having from 0.0025 to 0.1% w/w of micronized Formoterol, or an acid addition salt thereof, from 0.1 to 5.0% w/w ethanol,...
|
|
|
6051605 |
Method of treating psychosis and schizophrenia
This invention relates to compounds that are antagonists of dopamine D4 receptors, and to methods of treating psychosis and schizophrenia using a compound that is an antagonist of dopamine D4...
|
|
|
6051236 |
Composition for optimizing muscle performance during exercise
A nutritional composition in a dry powder form for optimizing muscle performance during exercise and for enhancing muscle cell repair and recovery following the cessation of exercise. The dry...
|
|
|
6046242 |
Use of aryl-substituted cyclobutylalkylamines for treating urinary incontinence
This invention discloses Ary-substituted cyclobutylalkylamine compounds of formula I ##STR1## in which R 1 and R 2 are as defined in the specification, and their use in treating incontinence in...
|
|
|
6043281 |
Nitromethyl ketones, process for preparing them and compositions containing them
The present invention relates to the compounds of formula: ##STR1## in which R 1 , R 2 , R 3 , E, A, X, Z, p and n are as defined herein. These compounds are aldose reductase inhibitors.
|
|
|
6034109 |
Method for protection of heart by limiting metabolic and ionic abnormalities developed during ischemia following ischemia or resulting from ischemia
A therapeutic and prophylactic method for protection of heart or heart tissue by limiting metabolic and ionic abnormalities developed during, following or associated with ischemia by administering...
|
|
|
6031003 |
Calcium receptor-active molecules
The present invention relates to the different roles inorganic ion receptors have in cellular and body processes. The present invention features: (1) molecules which can modulate one or more...
|
|
|
6022875 |
Use of substituted 2,4-imidazolidinedione compounds as analgesics
Disclosed in this invention is a method of analgesic treatment comprising administering an effective analgesic amount of a substituted 2,4-imidazolidinedione compound.
|
|
|
6020369 |
Method compositions and apparatus for treating and preventing respiratory viral infections
Respiratory viral infections may be effectively prevented or treated by administering an aerosol spray comprising a polyoxometalate to the lungs.
|
|
|
6017963 |
Formulation for intranasal administration
A dosage form for intranasal and/or inhalation administration of an analgesic having low opioid receptor binding activity to a warm blooded animal, that includes a pharmaceutically effective amount...
|
|
|
6015837 |
Method for treating scoliosis with β2-adrenoceptor agonists
A method of treating scoliosis by adminstering β 2 adrenergic agonists in amounts sufficient to correct the condition.
|
|
|
6013278 |
Liposomal antineoplaston therapies with markedly improved antineoplastic activity
A second generation of antineoplaston therapies with markedly improved antineoplastic activity is disclosed. Among others, members of the antineoplaston family include phenylacetate (PN),...
|
|
|
5990137 |
Method of inhibiting NADPH oxidase
The instant methods employs pharmaceutical compositions comprising aromatic azines; and imines, of the Formula 1 to selectively inhibit inflammation by preventing the oxidating burst from...
|
|
|
5990116 |
Trisubstituted phenyl derivatives
The invention concerns compounds of formula I ##STR1## wherein the substituents have various meanings, and their use in the prevention or treatment of inflammatory and proliferative skin diseases...
|
|
|
5985322 |
Method for the treatment of CNS disorders
An improved method for the treatment of central nervous system disorders comprises treating patients with an enteric fluoxetine formulation.
|
|
|
5972892 |
Topical composition containing a substance P antagonist
The invention relates to a therapeutic composition for topical application containing at least one product with an irritant side effect and a substance P antagonist for reducing or even eliminating...
|
|
|
5942549 |
Improving glucose tolerance
A compound of formula I ##STR1## or a pharmaceutically acceptable salt thereof in which R 1 and R 2 are independently H or methyl (for example N,N-dimethyl-1-...
|
|
|
5932246 |
Therapeutic uses of verapamil enantiomers
Substantially single enantiomer (R or S) verapamil, or a pharmaceutically-acceptable salt thereof provides an improved treatment for patients having a condition susceptible to treatment with...
|
|
|
5932196 |
Buffered emulsion compositions containing actives subject to acid or base hydrolysis
The present invention are for emulsion compositions and the process for making such compositions containing biological and cosmetic actives subject to hydrolysis of actives during processing and...
|
|
|
5932195 |
Arylaminomethylenecamphor derivatives
Arylaminomethylenecamphor derivatives of the formula (1) ##STR1## where the CC double bond is in the Z or E configuration, and the variables have the following meanings: R 1 H, CH 3 , R 2...
|
|
|
5929122 |
Combination preparation containing tramadol and a calcium channel antagonist
A pharmaceutical combination preparation, particularly for the treatment of pain, which contains a combination of the pain killer tramadol with at least one calcium channel antagonist, and a method...
|
|
|
5929101 |
Use of insulin sensitizing agents to treat hypertension
The present invention provides a method for treatin hypertension in insulin resistant patients comprising the administration of an insulin sensitizing agent, particularly ciglitazone or pioglitazone.
|
|
|
5925634 |
Use of ibogaine for treating neuropathic pain
This invention discloses that ibogaine, a plant derivative, can be used safely to treat neuropathic pain (i.e, pain which does not respond conventionally to opiate drugs such as morphine). Ibogaine...
|
|
|
5919826 |
Method of alleviating pain
The analgesic effectiveness of an tramadol is significantly enhanced by administering tramadol with the administration of an analgesia-enhancer which is a nontoxic NMDA receptor blocker and/or a...
|
|
|
5914343 |
Compounds and methods for inhibiting hyper-proliferative cell growth
The present invention features compounds and methods for inhibiting hyper-proliferative cell growth. The compounds and method are preferably used to treat patients having a hyperproliferative cell...
|
|
|
5902815 |
Use of 5HT-2A serotonin agonists to prevent adverse effects of NMDA receptor hypofunction
This invention relates to a new method for treating or preventing brain damage caused by NMDA receptor hypofunction (NR/hypo), using drugs such as lisuride which stimulate (agonize) activity at the...
|
|
|
5882731 |
Method of applying a mildewcide laden film and composition for the use therewith
A method is disclosed for applying a mildewcide compound laden film to surfaces by applying an aqueous, film-depositing composition onto said surfaces, allowing to stand momentarily, and rinsing...
|
|
|
5880120 |
Treating depression by administering an antidepressant
The present invention provides novel compounds such as certain aryloxy indanamines which are useful as anti-depressants and as inhibitors of synaptic norepinephrine and serotonin uptake. The...
|
|
|
5861435 |
Method for preventing settlement of aquatic fouling organisms
A method for preventing settlement of aquatic fouling organisms on surface of an aquatic structure without environmental hazard is provided. The method is based upon absolutely novel concept to...
|
|
|
5853463 |
Marine antifouling agent
Disclosed is a method of inhibiting the growth of marine organisms on a marine structure, by applying diphenyldiones. These compounds may be directly incorporated into the marine structure during...
|
|
|
5854254 |
Male contraceptives
Methods for achieving human male contraception are described in which compounds that substantially inhibit the movement of mannose lectins on the surface of human male sperm cells are administered...
|
|
|
5840719 |
Apoptosis inhibitors for treating neurodegenerative diseases
Apoptotic cell death in a fully differentiated, non-dividing cell such as a neuron is caused by an abortive attempt of the cell to re-enter or pass through the mitotic cycle. Therefore, agents...
|
|
|
5840764 |
Substituted hydroxy-anilino derivatives of cyclobutene-3,4-diones
The compound of the formula: ##STR1## wherein R 1 is straight chain alkyl, branched chain alkyl, cycloalkyl, hydroxyalkyl, fluoroalkyl, or polyfluoroalkyl; and one of R 2 , R 3 and R 4 is...
|
|
|
5833742 |
Phenylamides as marine antifouling agents
Disclosed is a method of inhibiting the growth of marine organisms on a marine structure, by applying onto or into the marine structure a phenylamide compound. These compounds may be directly...
|
|
|
5824650 |
Topical composition containing a substance P antagoinst
The invention relates to a therapeutic composition for topical application containing at least one product with an irritant side effect and a substance P antagonist for reducing or even eliminating...
|
|
|
5817698 |
Substituted cycloalkylamine derivatives and their use as calcium channel antagonists
A method of treatment of a condition or disease related to the accumulation of calcium in the brain cells of a mammal which comprises administering to a subject in need thereof an effective amount...
|
|
|
5804595 |
Kappa opioid receptor agonists
The invention provides certain amino acid conjugates of substituted 2-phenyl-N- 1-(phenyl)-2-(1-heterocycloalkyl- or heterocycloaryl-)ethyl!acetamides useful for selectively agonizing kappa opioid...
|
|
|
5801201 |
1-phenyl-2-dimenthylaminomethyl-cyclohexan-1-ol compounds as pharmaceutical active ingredients
1-phenyl-2-dimethylaminomethyl-cyclohexan-1-ol compounds, methods of preparing them and the use of these compounds in drugs are described.
|
|
|
5776952 |
Method and composition for topical therapy of back pain and muscle tension
A composition for topical therapy for symptoms of back pain, muscle tension or myofascial pain or a combination thereof, which comprises a topical carrier system for intact skin of the back or...
|
|
|
5767091 |
Analgesic effect enhancing preparations
The present invention provides an analgesic effect enhancing preparation capable of enhancement of the effect of analgesics, the preparation comprising as an active ingredient the following amino...
|
|
|
5767130 |
Use of kainic acid antagonists to prevent toxic side effects of NMDA antagonists
This invention discloses that kainic acid receptor antagonists (KA antagonists) can act as "safener" agents to reduce or prevent adverse side effects caused by NMDA antagonists. NMDA antagonists...
|
|
|
5747462 |
Pharmaceutically active compounds and their use
The present invention relates to the area of pharmacology; its objective is to solve the technical problem of inflammation, pain, pruritus and local hyperthermia in human beings and animal species....
|