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6358944 |
Methods and compositions for treating generalized anxiety disorder
The present invention relates to methods and compositions comprising a very low dose of cyclobenzaprine or metabolite thereof for preventing and treating Generalized Anxiety Disorder. The present...
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6355686 |
Cosmetic compositions containing substituted amine derivatives
Cosmetic methods and compositions containing selected substituted secondary amine aromatic compounds. The inventive compositions provide control of sebum secretion from sebocytes, improved oil...
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6355687 |
Cosmetic compositions containing substituted iminodibenzyl or fluorene derivatives
Cosmetic methods and compositions containing selected iminodibenzyl or fluorene derivatives. When used for skin or hair care, the inventive compositions provide control of sebum secretion from...
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6355685 |
Method of treating anxiety disorders
A compound of formula I or a pharmaceutically acceptable salt thereof in which R 1 and R 2 are independently H or methyl (for example...
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6346549 |
Treatment of pharmacology of drug misuse and other addictive disorders
A compound of formula I or a pharmaceutically acceptable salt thereof in which R 1 and R 2 are independently H or methyl (for example N , N...
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6344208 |
Pheromone baits for social insects
An insecticidal system for killing social insects comprises an insecticide together with a synthetic equivalent, such as 3-octanol, to at least one component of the alarm pheromone of the insect....
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6339106 |
Methods and compositions for the treatment and prevention of sexual dysfunction
Methods are disclosed for the treatment and prevention of sexual. The methods comprise the administration of a dopamine reuptake inhibitor and optionally an additional pharmacologically active...
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6335372 |
Treatment of obsessive compulsive disorder
A method for the treatment of OCD in a mammal by administering to the mammal an effective amount of 1,7,7-trimethylbicyclo[2.2.1]heptane derivative of Formula I wherein R is hydrogen or methyl,...
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6335323 |
Compositions for the treatment of peripheral neuropathies containing antidepressants and/or monoamine oxidase inhibitors and/or vitamin B12 and/or precursors or inducers of a neurotransmitter
Methods and compositions for treatment of a patient suffering from a form of peripheral neuropathy are disclosed. The method comprises administering to the patient any one of the following...
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6335371 |
Method for inducing cognition enhancement
A method for inducing cognition enhancement in a mammal by administering to the mammal an effective amount of 1,7,7-trimethylbicyclo[2.2.1]heptane derivative of Formula I wherein R is hydrogen...
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6331571 |
Methods of treating and preventing attention deficit disorders
Methods are disclosed for the treatment and prevention of affective disorders with racemic or optically pure sibutramine metabolites and pharmaceutically acceptable salts, solvates, and clathrates...
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6329403 |
Pharmaceutical composition for the treatment of diabetes
A pharmaceutical composition which comprises an insulin sensitizer in combination with an anorectic, which is useful as an agent for preventing or treating diabetes.
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6329405 |
Cyclobutene derivatives, their preparation and their therapeutic uses
Compounds of formula (I): ##STR1## {wherein: R 1 and R 2 each represents a variety of organic groups; R 3 and R 4 each represents hydrogen or a variety of organic groups; A represents a...
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6326404 |
Use of O-desmethyl-N-mono-desmethyl-tramadol
This invention relates to a method of treating pain, urinary incontinence, diarrhea or pruritus using O-desmethyl-N-mono-desmethyl-tramadol.
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6326027 |
Controlled release formulation
A controlled release preparation for oral administration contains tramadol, or a pharmaceutically acceptable salt thereof, as active ingredient.
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6326402 |
Methods for treating viral infections using a compound capable of inhibiting microtubules
The present invention is directed to a method for inhibiting viral replication and treating viral infections by administering a pharmaceutically effective amount of a compound capable of binding a...
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6313174 |
Aminobenzophenones as inhibitors of interleukin and TNF
The compounds of the present invention are represented by general formula (I) in which formula R 1 and R 2 stand independently for one or more, similar or different substituents selected from the...
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6306437 |
Apomorphine-containing dosage forms for ameliorating male erectile dysfunction
Psychogenic impotence can be ameliorated without substantial undesirable side effects by administration of apomorphine and an antiemetic agent in an amount sufficient to substantially reduce nausea...
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6303569 |
Trialkyl-lock-facilitated polymeric prodrugs of amino-containing bioactive agents
The present invention is directed to double prodrugs containing polymeric-based transport forms. These polymeric compounds comprise the formula: ##STR1## wherein: B is H, OH, OSiR 13 , a...
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6297286 |
Therapeutic use and formulation
Substantially single-enantiomer(-)-tramadol, and its metabolites and structural and/or functional analogues, are useful for the prevention and/or treatment of one or more symptoms selected from...
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6297287 |
Anti-arrhythmic composition and methods of treatment
Pharmaceutical compositions for the treatment of cardiac arrhythmia comprising an effective anti-arrhythmic amount of at least one compound in association with a pharmaceutically acceptable,...
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6291533 |
Dietary supplements for each specific blood type
Dietary supplement compositions designed to be responsive to specific blood types, and thus most beneficial for people with specific antigenic blood types.
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6288125 |
Treatment of hiatial hernia
A compound of formula I ##STR1## or a pharmaceutically acceptable salt thereof in which R 1 and R 2 are independently H or methyl (for example...
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RE37355 |
6-dimethylaminomethyl-1-phenyl-cyclohexane compounds as pharmaceutical active ingredients
6-dimethylaminomethyl-1-phenyl-cyclohexane compounds, methods of preparing them and the use of these compounds in drugs are described.
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6277829 |
Process for preparing of aqueous formulation for opthalmic use
The present invention describes a process for the preparation of aqueous formulations containing azithromycin for ophthalmic use, as well any formulations obtained by this process and their topical...
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6271264 |
Polymers containing spirobicyclic ammonium moieties as bile acid sequestrants
The present invention relates to a method for sequestering bile acids in a patient and to particular polymers for use in the method. The method comprises administering a therapeutically effective...
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6268398 |
Compounds and methods for treating mitochondria-associated diseases
Compounds, compositions and methods are disclosed for treating mitochondria-associated diseases, such as cancer, psoriasis, stroke, Alzheimer's Disease and diabetes. The compounds of this invention...
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6265412 |
Minoxidil compositions for external use
There is provided a composition for external use with a reduced skin irritation comprising minoxidil and 0.01 to 2 parts by weight of at least one antihistaminic agent selected from the group...
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6254887 |
Controlled release tramadol
A controlled release preparation for oral administration contains tramadol, or a pharmaceutically acceptable salt thereof, as active ingredient.
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6255350 |
Stabilized concentrates of water unstable AZA compounds and o/w miniemulsions thereof
This invention relates to a single phase emulsifiable concentrate composition comprising (a) between about 0.05 and about 25 wt. % of a biologically, fungicidally and/or herbicidally active aza...
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6245774 |
Tri-substituted phenyl or pyridine derivatives
Compounds of general formula (1) are described: ##STR1## wherein W-- is (1) C(Y)-- where Y is a halogen atom, or an alkyl or --XR a group where X is --O--, --S(O) m -- [where m is zero...
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6235793 |
Use of agonists of adrenergic β-3 receptors for preparing wound-healing medicines
The invention relates to the use of β 3 -adrenergic receptor agonists for the preparation of healing drugs and to the pharmaceutical compositions for said use.
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6235736 |
3-anilino-2-cycloalkenone derivatives
A 3-anilino-2-cycloalkenone derivative of the formula (I): ##STR1## wherein, R 1 represents a C 1 to C 8 alkyl group, which may have a substituent, except for a methyl group, a C 3 to C 7 ...
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6232347 |
Treatment of osteoarthritis
A compound of formula I ##STR1## or a pharmaceutically acceptable salt thereof in which R 1 and R 2 are independently H or methyl (for example...
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6231651 |
Enhanced wood preservative composition
A wood preservative composition comprising at least one biocide, such as an iodopropargyl compound or a triazole compound, in combination with at least one antioxidant, such as a hindered phenol, a...
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6217914 |
Ascorbic acid composition and method for treatment of aging or damaged skin
An ascorbic acid-based composition and related method for the treatment of aging or photo-damaged skin is disclosed. The composition includes water and ascorbic acid, at least a portion of which...
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6197827 |
Nicotine addiction treatment
The present invention encompasses methods of treating patients for tobacco addiction and nicotine addiction, for palliating the effects of nicotine withdrawal, for providing or facilitating the...
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RE37087 |
Insecticidal triffluormethyl alkane derivatives
There are provided new alkane and alkoxyalkane derivatives of the general formula I ##STR1## in which R 1 , R 2 , R 3 , R 4 and A have the meanings given in the description, processes for their...
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6194399 |
Aryldiamine derivatives useful as antibacterial agents
Disclosed are pharmaceutical compositions and formulations comprising the compound: ##STR1## wherein: (a) R 1 , R 2 , R 3 , and R 4 are independently selected from the group consisting of...
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6187820 |
Medical treatment to improve lipid levels
A compound of formula I ##STR1## or a pharmaceutically acceptable salt thereof in which R 1 and R 2 are independently H or methyl (for example...
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6177472 |
Regulation of alzheimer's disease proteins and uses thereof
A method of regulating the assembly of the protein tau in the brain of a mammal in need of such treatment comprising the step of administering to said mammal a pharmacologically effective amount of...
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6174925 |
Use of sibutramine analogues to prevent the development of diabetes
A compound of formula (I) or a pharmaceutically acceptable salt thereof in which R 1 and R 2 are independently H or methyl (for example N,N-dimethyl-1-[1-(4-chlorophenyl)cyclobutyl]-3-methylbutyl...
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6166013 |
Glucocortiocoid-selective agents
Compounds having Formula I ##STR1## are useful for modulating the glucocorticoid receptor in a mammal. Also disclosed are pharmaceutical compositions comprising compounds of Formula I and methods...
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6162832 |
2-Phenoxyaniline derivatives
A 2-phenoxyaniline derivative represented by the formula: ##STR1## wherein R 1 is a hydrogen atom or a lower alkoxy group, R 2 is a halogen atom or a nitro group, and R 3 is a hydrogen atom or a...
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6162831 |
Medical treatment to lower uric acid levels
A compound of formula I ##STR1## or a pharmaceutically acceptable salt thereof in which R 1 and R 2 are independently H or methyl (for example...
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6150412 |
Catechol derivatives
The invention relates to compounds of formula (I) ##STR1## wherein R 1 is an electronegative substituent, preferably nitro, cyano, formyl or carboxy, R 2 is --A--R 4 , wherein A is a branched or...
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6143776 |
Tosylproline analogs as thymidylate synthase inhibitors
Tosylproline analogs of formula I, methods of making them, pharmaceutical compositions containing them, and methods for their use. The compounds are thymidylate synthase inhibitors; and are useful...
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6139879 |
Fungicidal and bactericidal compositions for plants containing compounds in the form of heavy metal
The present invention relates to heavy metal chelate compositions, which are used as fungicides and bactericides, and methods of using the compositions. In particular, the present invention relates...
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6127422 |
Anti-viral method
A method of inhibiting an envelope virus selected from the group consisting of influenza bovine diarrheal, hepatitis C and tick borne encephalitis virus that udergoes hemagglutinin-mediated fusion...
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6127424 |
Aryl-substituted cyclobutylalkylamines for treating obesity
Use of aryl-substituted cyclobutylalkylamines and their pharmaceutically suitable salts for treating obesity and its accompanying disorders are disclosed.
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