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7354954 |
Use of GABA agonists for treatment of spastic disorders, convulsions, and epilepsy
According to the subject invention, there is disclosed a method for treating a patient/subject having a spastic disorder, a convulsive disorder, pain or epilepsy which includes administering to the...
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6914078 |
Triarylmethane derivatives and their use as photochemotherapeutic agents
Disclosed are compounds having one of the following structures:
wherein R and R′ are hydrogen or substituted or unsubstituted C 1 to C 6 linear or branched alkyl, and at least one X is a...
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6878749 |
Method of treating metabolic disorders, especially diabetes, or a disease or condition associated with diabetes
The invention relates to a combination, such as a combined preparation or pharmaceutical composition, respectively, which comprises nateglinide (1) stet
or repaglinide and at least one other...
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6656967 |
Fungicidal phenylimidate derivatives
The invention provides fungicidal compounds of formula I and salts thereof: wherein the various radicals and substituents are as defined in the description, fungicidal compositions containing...
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6559185 |
Nitromethyl ketone compounds having aldose reduction inhibiting properties and methods for their use
The present invention relates to the compounds of formula: in which R 1 , R 2 , R 3 , E, A, X, Z, p and n are as defined herein. These compounds are aldose reductase inhibitors.
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6541520 |
Treatment of addiction and addiction-related behavior
The present invention provides a highly efficient method for treating substance addiction and for changing addiction-related behavior of a mammal suffering from substance addiction. The method...
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6534546 |
Aniline derivatives possessing an inhibitory effect of nitric oxide synthase
Compounds represented by the general formula (1): (where R 1 is SR 6 or NR 7 R 8 , where R 6 is typically an alkyl group having 1-6 carbon atoms, R 7 is a hydrogen atom, an alkyl group...
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6399542 |
Alkoxyimino-substituted bicyclic compounds compositions containing the same and method of making such compounds
Alkoxyimino-substituted bicyclic derivatives or salts thereof having an excellent effect of controlling diseases and insect pests are disclosed. These derivatives are represented by the following...
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6258852 |
Aryl nitrone therapeutics for the treatment of inflammatory bowel disease
Disclosed are methods for treating or preventing inflammatory bowel disease (IBD) using aryl nitrone compounds. Pharmaceutical compositions containing aryl nitrone compounds which are useful for...
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6187808 |
Hexahydro-naphthalenone oximes and hydrazones
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RE37020 |
Method for providing nutrition to elderly patients
The present invention provides a method for providing nutrition to elderly patients. Pursuant to the present invention, the enteral composition includes a protein source, a lipid source, and a...
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6166032 |
Method for controlling tobacco use and alleviating withdrawal symptoms due to cessation of tobacco use
A method for controlling tobacco use and alleviating withdrawal symptoms due to the cessation of tobacco use comprising administering to a human desiring to control tobacco use and/or suffering...
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6075044 |
Heterocyclic derivatives as inhibitors of purine salvage phosphoribosyltransferases
The use of certain heterocyclic derivatives for treating parasitic protozoa infections in mammals, in particular bovine trichomoniasis and giardiasis, is disclosed.
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6043281 |
Nitromethyl ketones, process for preparing them and compositions containing them
The present invention relates to the compounds of formula: ##STR1## in which R 1 , R 2 , R 3 , E, A, X, Z, p and n are as defined herein. These compounds are aldose reductase inhibitors.
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6020374 |
Biologically active synthetic dye compounds
A pharmaceutical composition comprising, in admixture with a pharmaceutically acceptable carrier, a therapeutically effective amount of a polyaromatic ring-containing compound, capable of mimicking...
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6020369 |
Method compositions and apparatus for treating and preventing respiratory viral infections
Respiratory viral infections may be effectively prevented or treated by administering an aerosol spray comprising a polyoxometalate to the lungs.
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5990151 |
Optically active substituted phenylalkylamine derivatives
The present invention relates to an optically active, substituted phenylalkylamine derivative represented by Formula [1]: ##STR1## wherein A is a substituted or non-substituted phenyl or thienyl; X...
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5962463 |
Methods of stimulating non-amyloidogenic processing of the amyloid precursor protein
Stimulating non-amyloidogenic processing by the activation of cell surface serotonin receptors linked to phospholipase and protein kinase C is described. Activation of the cell surface serotonin...
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5869067 |
Bi-aromatic compounds and pharmaceutical and cosmetic compositions
The present invention relates to new aromatic compounds, to their preparation and to their use in human and veterinary medicine and in cosmetic compositions.
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5861435 |
Method for preventing settlement of aquatic fouling organisms
A method for preventing settlement of aquatic fouling organisms on surface of an aquatic structure without environmental hazard is provided. The method is based upon absolutely novel concept to...
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5824684 |
Method for treating drug and alcohol addiction
A method for treating treating drug and alcohol addiction comprising administering to a human suffering from such addiction an effective amount of an acetylcholine esterase reactivator.
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5763479 |
Naphthoquinone derivatives for the treatment of chronic inflammation
A redox, hydrogen-acceptor compound, having utility in treating inflammation, is a 1,4-dioxonaphthalene or 1,4-dilminon aphthalene having either a 2,3-double bond, in which cast there are 2 and...
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5760052 |
Composition for use as a fungistat and for the treatment of fungal infections
A composition for use as a fungistat for the treatment and prevention of infections such as sporotrichosis, onychomycosis infections, white line disease, hoof rot, jungle rot, pseudallecheria...
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5705531 |
1,5-disubstituted 7A-methylperhydroinden-3A-ol derivatives, useful in treating cardiovascular disorders, processes for their preparation and pharmaceutical compositions containing the same
1,5-Disubstituted 5a-methylperhydroinden-3a-ol derivatives of formula (I): ##STR1## where either the symbol - - - - represents a single bond, the group A is in cis configuration with respect...
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5519018 |
Substituted phenols and their use for the treatment of disorders caused by cell proliferation
Substituted phenols of the formula I ##STR1## processes for their preparation and compositions containing substituted phenols of the formulae I and II ##STR2## for the treatment of disorders caused...
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5461078 |
Anti-cancer compounds
Compounds of formula (I) ##STR1## in which R 1 is CHCHR, CHNNHR, CHN--A--N(O)R'R" or CH 2 --NH--A--N(O)R'R" and R 2 is separately selected from hydrogen, CHCHR, CHNNHR,...
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5438073 |
Dermatological and/or cosmetological composition containing retinoids
Dermatological and/or cosmetological compositions containing at least one retinoid of general formula (I), ##STR1## and the use of such compounds for preparing dermatological and/or cosmetological...
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5276046 |
Hydrazine derivatives
A hydrazine derivative of formula (I), ##STR1## wherein A represents an optionally substituted phenyl, naphthyl or heteroaromatic group containing one or two nitrogen atoms, and R 1 represents...
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5134167 |
1-Azabutadienes and fungicides containing these compounds
1-Azabutadienes of the formula ##STR1## where R 1 and R 2 are each phenyl, biphenyl, naphthyl or pyridyl, and these radicals may be substituted, or are each alkyl which is unsubstituted or...
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5112869 |
Substituted 1-phenylnaphthalenes
This invention concerns compounds having the structure: ##STR1## wherein each of R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 2 ', R 3 ', R 4 ', and R 5 ', is independently hydrogen (--H), or a hydroxyl...
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5079245 |
2-trifluoromethyl-7-substitute-6,7,8,9-tetrahydro-[5H]-benzocycloheptenes
The compounds 2-trifluoromethyl-7-substituted-6,7,8,9-tetrahydro-[5H]-benz
ocycloheptenes are disclosed and disclosed to be useful in the treatment of metabolic illnesses such as diabetes, obesity,...
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4992453 |
Certain thioimidate and amidine insecticides
Insecticidal compounds having the formula ##STR1## in which R is an optionally substituted aryl moiety; R 2 is an optionally substituted alkyl, cycloalkyl or alkenyl moiety, X is sulfur, amino or...
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4946865 |
Dipropargyloxybenzene compounds and their production
A compound of the formula: ##STR1## wherein X is a hydrogen atom, a halogen atom, a C 1 -C 3 alkyl group or a C 1 -C 3 alkoxy group and Y is a hydrogen atom, a halogen atom, a cyano group, a...
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4921872 |
Acaricidal agents based on azomethines of 2,3-diaminomaleic acid nitrile
A method of combating acarids which comprises applying to such acarids or to an acarid habitat an acaricidally effective amount of an azomethine of 2,3-diaminomaleic acid nitrile of the formula...
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4588748 |
Therapeutically useful benzylidene derivatives
Benzylidene derivatives of the formula: ##STR1## wherein n is 3, R represents an amino or hydroxy radical, or a group --OM in which M is an alkali metal, X 1 and X 2 are both Cl, and X 3 is...
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4564636 |
Diphenylazomethines and pharmaceutical compositions containing them
Diphenylazomethines of the formula (I) ##STR1## in which R represents --(CH 2 ) 4 OH, --(CH 2 ) 2 --CHOH--CH 3 , --CH 2 --CHOH--C 2 H 5 , --CH 2 --CHOH--CH 2 --COOH, --CH 2 --CHOH--CH 2 ...
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4333930 |
Orthoarylideneaminophenethylamines and pharmaceutical compositions
Compounds, exhibiting central nervous system activity, of the formula ##STR1## wherein R 1 is phenyl which is unsubstituted or substituted by at least one member selected from the group consisting...
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4230727 |
Compositions and method of treatment
Compositions for inhibiting cellular proliferation in mammals containing as the active ingredient N-benzylideneaniline and its derivatives, and the method therefor.
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4220663 |
Combating pests with benzyl phenyl ethers
Benzyl phenyl ethers, many of which are new, of the formula ##STR1## in which X is ##STR2## R 1 is H or alkyl, R 2 is alkyl, alkenyl, alkynyl, alkylidene, alkenylidene or alkynylidene optionally...
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4126701 |
Process of sparing poultry from the effect of toxins
A process of feeding animals and poultry a complete feed consisting only of (i) between 0.00077 and 0.005 percent by weight, based on the weight of the feed, of gentian violet and (ii) the...
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4044152 |
Methods of preparing methylrosaniline chloride anti-microbial compositions
An animal or poultry feed additive which is effective for inhibiting or preventing microbial activity, fungi and mold growth in feeds to which it is added provided by dispersing methylrosaniline...
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3929999 |
Oral hypoglycemic method
An oral hypoglycemic compound for use in the treatment of diabetes mellitus having the general formula ##SPC1## And which is one of the group consisting of: A. the compound wherein R 1 is an...
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3916027 |
Method of treating candida albicans infections in poultry
A premix concentrate for addition to animal and poultry feed which consists essentially of gentian violet, which is a selective fungicidal mold inhibitor of Candida albicans and the remainder inert...
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3721741 |
COMBATTING PHYTOPATHOGENIC FUNGI ON PLANTS WITH SUB-PHYTOLOXIC FUNGICIDALLY EFFECTIVE AMOUNTS OF HERBICIDAL N-PHENYL DERIVATIVES OF 3,5-DIHALO-SALICYLALDEHYDE
A preparation for combating harmful insects, acarides, nematodes phytopathogenic fungi and bacteria, which comprises, as active substance, a compound of general formula wherein X 1 and X 2 ...
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3507963 |
COMPOSITIONS AND METHODS FOR CONTROLLING FUNGI WITH N-BENZYLIDENE ALKYLAMINES
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3487156 |
COMBATING INSECTS,THEIR EGGS,OR ACARIDS ON PLANTS
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3378437 |
Acaricidal agents
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3357883 |
Fungicidal nu-substituted derivatives of halogenated salicylideneimines
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3328251 |
Pharmaceutical compositions and methods utilizing 2-aminoadamantane and its derivatives
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3287222 |
Method for preparation of synthetic fiber medical dressing impregnated with therapeutic
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