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5290775 |
Euthanasia compositions
An euthanasia solution based upon gamma-hydroxybutramide, a cardiotoxic amount of a compound selected from a chloroquine and quinacrine compound and lidocaine as a base or as a water soluble salt...
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5260340 |
Prevention and amelioration of acetaminophen toxicity with beta-carotene
A method for preventing acetaminophen toxicity in a mammal is provided. An acetaminophen toxicity inhibiting amount of beta-carotene is administered before, simultaneously with, after, or any...
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5231087 |
Treatment of skin diseases and tumors with esters and amides of monocarboxylic acids
Noninfectious inflammatory and hyperpigmentation skin diseases, thermal injuries and premalignant skin tumors induced by radiation or virus, in both humans and animals, are treated with topical...
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5217987 |
Dopamine uptake inhibitors in reducing substance abuse and/or craving
Mazindol and other nonreinforcing dopamine uptake inhibitors are effective to lessen craving for abused substances.
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5212193 |
Antimicrobial compositions comprising 3,4-dichloroanilides and isothiazolones and methods of controlling microbes
A synergistic antimicrobial composition comprising a 2-alkyl-3-isothiazolone and a 3,4-dichloroanilide of the formula ##STR1## where n is an integer from 1 to 2, in a ratio to each other which...
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5189065 |
Use of derivatives of 9,10-dihydrophenanthrene for the preparation of an anti-tumor medicament
The use of products of formula (I) is described, wherein X and Y represent hydrogen, hydroxy or alkoxy; and R 1 and R 2 represent H, alkyl, alkenyl or alkynyl, arylalkyl, acyl or R 1 and R 2 ...
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5182306 |
Use of colchicine for the control of retroviruses
This invention relates to treating vetrovirus of the leutivirous group with colchicine.
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5182305 |
N-aryl and N-cycloakyl neoalkanamide insect repellents
N-monosubstituted neoalkanamides of 11 to 14 carbon atoms wherein the substituent on the amide nitrogen is cyclic (aromatic or cycloaliphatic, such as aryl or cycloalkyl) and of at least five...
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5182304 |
N-lower alkyl neodecanamide insect repellents
N-lower alkyl neoalkanamides (N-lower alkyl trialkylacetamides of certain types) of 1 to 4 carbon atoms in the lower alkyl thereof and of 5 to 14 carbon atoms in the neoalkanoyl (or trialkylacetyl)...
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5164413 |
Acne treatment
Acne can be treated by applying to the skin of a subject a composition containing one of a certain group of acids, acid halides or amides.
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5153227 |
Phenylsulfonyl nitromethanes as aldose reductase inhibitors
The invention concerns novel pharmaceutical compositions for use in the treatment of certain complications of diabetes and galactosemia and which contain a nitromethane derivative (or its non-toxic...
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5151446 |
Substituted 2-amidotetralins as melatonin agonists and antagonists
The present invention relates generally to compounds having melatonin receptor activities and in particular to substituted 2-amidotetralin derivatives; to pharmaceutical preparations comprising...
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5141961 |
Process for solubilizing difficulty soluble pharmaceutical actives
The present invention relates to a process for solubilizing at least one difficultly soluble pharmaceutical active in a mixture of polyethylene glycol and polyvinylpyrrolidone. The process does not...
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5132107 |
Two-phase cleansing, conditioning and medicinal treatment shampoo
Two phase shampoo allowing sequential application of substances/conditions, especially for controlling dandruff, wherein the first phase consists of a detergent composition, together with possible...
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5114975 |
Anilinophenyl carbodiimides compositions containing them, and the use thereof in pest control
The invention relates to novel substituted aryloxyphenylthioureas, aryloxyphenylisothioureas and aryloxyphenylcarobodiimides of formula I ##STR1## wherein R 1 is C 1 -C 12 alkyl, unsubstituted...
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5079264 |
Chemical process
A process to prepare compounds of formula I ##STR1## in which n=0, 1 or 2 comprising the cyclization of compounds of formula II ##STR2## in which n=0, 1 or 2. The cyclization may be effected in the...
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5077314 |
Agricultural gel-forming compositions
A method is disclosed for the containment and controlled release of and the substantial reduction of the leaching from the site of application of agricultural chemicals. In the disclosed method,...
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5071843 |
Combination of 2-substituted carbapenems with dipeptidase inhibitors
A combination of a carbapenem of the formula: ##STR1## where R is H or CH 3 and R 1 is ##STR2## with a renal dipeptidase inhibitor is disclosed.
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5071875 |
Substituted 2-amidotetralins as melatonin agonists and antagonists
The present invention relates generally to compounds having melatonin receptor activities and in particular to substituted 2-amidotetralin derivatives; to pharmaceutical preparations comprising...
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5066678 |
Phenethandamine derivatives and pharmaceutical use thereof
The invention relates to compounds of the general formula (I) ##STR1## and physiologically acceptable salts and solvates thereof; wherein; R 1 and R 2 each independently represent a hydrogen...
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5059620 |
Aryl substituted aminomethyl benzene derivatives
The present invention relates to new compounds of the formula ##STR1## wherein X is ##STR2## wherein R 1 is hydrogen, lower alkyl, phenyl, benzyl, cinnamoyl, thiophene, furan, pyrrole, imidazole,...
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5057500 |
Treatment of pruritis with esters and amides
This invention relates to a new topical pharmaceutical composition for the treatment of pruritis, especially psychogenic and senile types, that contains esters and amides of 5 to 19 carbon atom...
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5053430 |
Use of 2,7-diamino-1,2,3,4-tetrahydronaphthalenes as medicaments, new 2,7-diamino-1,2,3,4-tetrahydronaphthalenes and processes for their preparation
Novel compounds having the general formula ##STR1## wherein R 1 , R 2 , R 3 and R 4 are as defined herein. These compounds are useful in the treatment of schizophrenia.
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5051450 |
Diiodomethylsulfone insecticides
A composition comprising a compound of the formula: ##STR1## wherein R is R 1 CH 2 ) n , wherein n is 0 to 4 and R 1 is loweralkyl, phenyl, monoloweralkylphenyl, monohalophenyl, nitrophenyl,...
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5026731 |
Pharmaceutical composition and method of treating psychoses
A method of treating psychoses in a mammal which comprising administering to a mammal in need of such treating an antipsychotic effective amount of a compound represented by ##STR1## wherein R is a...
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5026730 |
Anilinophenylthioureas, compositions containing them, and the use thereof in pest control
The invention relates to novel substituted anilinophenylthioureas, anilinophenylisothioureas and anilinophenylcarbodiimides of formula I ##STR1## wherein R 1 is C 1 -C 12 alkyl, unsubstituted or...
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5025038 |
Process for the preparation of antimicrobial formulations of 2-(alkylthio)ethanamine hydrohalides
A method for preparing antimicrobial formulations of 2-(alkylthio)ethanamines hydrohalides is disclosed. The formulations are prepared directly from the hydrolysis product of 2-(alkylthio)ethyl...
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5021414 |
Phenol derivatives
A phenol derivative of the formula NU--A--X--R 1 wherein NU is a defined bis-phenolic nucleus including a hydroxyphenyl-hydroxynaphthyl; hydroxyphenyl-hydroxyindanyl,...
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5015665 |
N-alkyl neotridecanamide insect repellent compositions
N-lower alkyl neoalkanamides of 1 to 4 carbon atoms in the lower alkyl thereof, and of 12 to 14 carbon atoms in the neoalkanoyl group, e.g., N-methyl- and N-ethyl neotridecanamides, are new...
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5011854 |
Hydroxamic acid derivatives and use thereof in combatting lipoxygenase-mediated diseases
A hydroxamic acid compound represented by the general formula (I) or a salt thereof; ##STR1## wherein R 1 represents a hydrogen atom, or a substituted or unsubstituted alkanoyl group, R 2 ...
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4980366 |
Amide, sulfonamide, urea, carbamate, thiocarbamate, and thiourea derivatives of 4'hydroxybenzylamine having anti-inflammatory and analgesic activity
Novel 4'-hydroxybenzylamine derivatives of the formula ##STR1## pharmaceutical compositions and methods of use thereof are the present invention. Utility is for the treatment of arthritis, asthma,...
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4975461 |
P-aminophenols, derivatives thereof and method of use
p-Aminophenols are provided having the structure ##STR1## wherein m is 0, 1 or 2; n is 0, 1, 2 or 3; R 1 and R 2 may be the same or different and are H, hydroxy or alkoxy; R 3 is H, lower alkyl,...
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4959390 |
Polyhydroxybenzyloxypropanolamines
Compounds of the present invention, are represented by the general formula ##STR1## wherein R 1 group which may be alkyl of from 1 to about 6 carbon atoms, alkenyl of from 2 to about 6 carbon...
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4943565 |
Analgesic tablet of aspirin and caffeine containing low-substituted hydroxypropyl cellulose
An analogesic tablet containing aspirin, acetaminophen and caffeine of improved dissolution rate containing low-substituted hydroxypropylcellulose.
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4937266 |
Inhibitory agent of hepatic fibrosis
An inhibitory agent of hepatic fibrosis containing pantethine as an active ingredient.
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4937267 |
Method of treatment of obesity
A method of treatment of obesity or diabetes mellitus in a warm-blooded animal requiring such treatment which comprises administering to said animal an effective amount of the compound...
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4908386 |
Ethanolamine derivatives
The present invention provides compounds of general formula (I) ##STR1## wherein Ar represents an unsubstituted or substituted phenyl gorup; R 1 and R 2 each represents a hydrogen atom or a C...
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4904697 |
Controlling the growth of certain tumor tissue with chalcone derivatives
Certain chalcone derivatives are reported to inhibit the polymerization of tubulin to form microtubules and are therefore antimitotic agents which can be used to control the growth of tumor tissue...
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4904662 |
Raising of pigs
The fat content of sows' milk is increased, thereby increasing the energy supplied to the sow's piglets, by administering one of a small group of phenethanolamines.
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4902676 |
Compositions comprising N,N-dialkylalkanamides
This invention provides compositions comprising a physiologically-active agent and a compound represented by the general formula ##STR1## wherein R 1 and R 2 are independently selected from the...
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4898729 |
Treatment of hypertension, compounds and compositions for antihypertension and diuresis
Antihypertension action is achieved without diuresis by administration of a thiazide diuretic in an amount which while being sufficient to achieve antihypertension is insufficient to achieve...
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4882339 |
4-Amino-substituted 1,2-dihydroxynaphthalene derivatives useful in inhibiting 5-lipoxygenase activity in mammals
Disclosed are compounds of the formula ##STR1## wherein R 1 represents unsubstituted or lower alkyl-substituted C 3 -C 7 -cycloalkyl, unsubstituted or lower alkyl substituted C 7 -or C 8 ...
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4880834 |
Method for administering ethanolamine derivatives to livestock
A method for treating livestock to decrease birth mortality rate and to increase post-natal survival rate by administering ethanolamine derivatives is disclosed.
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4863968 |
Methods of treating gout with chalcone derivatives
Certain chalcone derivatives are reported to inhibit the polymerization of tubulin to form microtubules and are therefore antimitotic agents which can be used as antigout agents. The chalcone...
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4859706 |
Pesticidal composition and process for combating pests employing carboxamides
Carboxamides of the general formula I ##STR1## where R 1 is C 1 -C 6 -alkyl, C 2 -C 6 -alkenyl, C 2 -C 6 -alkynyl, C 3 -C 10 -cycloalkyl, C 3 -C 10 -cycloalkyenyl or C 4 -C 10 ...
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4855294 |
Method for reducing skin irritation associated with drug/penetration enhancer compositions
A composition and method for reducing the skin irritation properties of a transdermal drug/enhancer composition which comprises incorporating into said composition, either prior to or at the time...
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4853381 |
Ethanolamine compounds
The invention provides compounds of the general formula (I) ##STR1## wherein Ar represents a phenyl group optionally substituted by one or more substituents selected from halogen atoms, or the...
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4853382 |
Aminophenol derivatives
The invention provides compounds of the general formula (I) ##STR1## wherein Ar represents a phenyl group optionally substituted by one or more substituents selected from halogen atoms, or the...
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4851441 |
Antiviral guanidine derivatives compositions and their methods of use
This invention relates to antiviral organic guanidine derivatives compositions; a process of producing the antiviral compositions; and a method for inhibiting viruses utilizing the compositions....
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4851447 |
N-2,3-butadienyl-1,4-butanediamine derivatives
1. A compound of the formula: H 2 CCCHCH 2 NHCH 2 --Z--CH 2 NHR wherein: Z is --CH 2 CH 2 -- or trans--CHCH--, R is H, CH 3 --, CH 3 CH 2 , CH 3 (CH 2 ) 2 --, --(CH 2 ) 3...
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