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7560484 |
Vaccine preparation containing fatty acid as a constituent
The present invention provides an adjuvant that is a hydroxy unsaturated fatty acid or a derivative thereof, as well as a vaccine preparation containing the adjuvant as a constituent. For example,...
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7482479 |
Production of cis-pellitorin and use as a flavouring
The invention describes a process for the production of 2E,4Z-decadienoic acid-N-isobutylamide (cis-pellitorine) and its use as a pungent principle and aromatic substance having a heat-generating...
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7445931 |
Compositions and methods for enrichment of neural stem cells using ceramide analogs
The present invention provides compositions and methods for human neural cell production. More particularly, the present invention provides cellular differentiation methods employing amphiphilic...
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7196119 |
Development of new selective estrogen receptor modulators
The present disclosure concerns a new class of selective estrogen receptor modulators (SERMs). The disclosure also includes the identification of a previously unknown membrane associated estrogen...
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7060307 |
Topical composition for heightened sensitivity
The invention is directed to a topical composition for heightened sensitivity and arousal for humans. The topical composition includes an organic fluid carrier, preferably glycerin, containing an...
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7015251 |
Combinations of ceramide and chemotherapeutic agents for inducing tumor cell death
This invention provides a method for increasing apoptosis in tumor cells and a method of decreasing a size of a tumor, said methods comprising contacting the tumor cells with: a) an effective...
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6956059 |
Anti-inflammatory and immunomodulatory amino acid derivatives, their preparation and use
The present invention ralates to compounds of formula (I): wherein R is hydrogen (H) or C 1-6 alkyl; and X is defined such that —NH—(X)—COOH is the residue of an amino acid, which amino acid...
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6916852 |
Method for regulation of microvascular tone
Methods and kits for regulating arterial microvascular tone in which a COX-2 inhibitor and a cannabinoid receptor agonist are co-administered to a subject.
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6734204 |
Serotonin potentiation by oleamide analogs
Analogs related to oleamide are employed for potentiating the 5-HT 2A and 5-HT 1A responses to serotonin (5-HT). With respect to the potentiation of the 5-HT 2A receptor response, it is...
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6699851 |
Cytotoxic compounds and their use
Novel amides of polyunsaturated fatty acids with cysteamine-S-phosphate have been synthesized. Combinations of the all-trans-retinoic acid and/or amides of the 13-cis-retinoic acid with...
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6689399 |
Transdermal delivery of an anti-inflammatory composition
The present invention provides an anti-inflammatory composition for treatment of joint and muscle pain through transdermnal delivery of a capsacinoid in conjunction with glucosamine. The...
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6685953 |
External preparation compositions
The present invention relates to a dermatologic preparation containing a diamide derivative represented by the following formula (1): (wherein, R 1 represents a linear or branched hydrocarbon...
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6656972 |
Control of pain with endogenous cannabinoids
Novel pharmaceutical therapeutic compositions and methods for using same for the treatment of pain experienced by an individual are provided. The compositions contain at least one member selected...
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6632839 |
Capsicum based disinfectant and sterilizant
A method and formulation for sterilizing and disinfecting surfaces, and for killing bacteria on contact, the sterilizing and disinfecting formulation containing water and between about 0.0001...
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6605641 |
20-HETE antagonists and agonists
20-HETE agonists and antagonists are disclosed along with therapeutic applications. In a preferable form of the invention, the 20-HETE agonists are selected from the group consisting of...
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6599941 |
Insecticide and insect repellant compositions
A non-toxic, environmentally safe and easily employable insecticide and insect repellent is achieved by providing an aqueous composition incorporating ethanolamine based compounds, either...
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6593371 |
Treatment for wart and related disorders
A novel treatment for wart and related disorders such as papillomas derived from extracts of pepper, ginger, and related plant species containing vanillyl (FIG. 3 ), and piperidine (FIG. 7 ) ring...
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6593370 |
Topical capsaicin preparation
A topical capsaicin preparation for the treatment of painful cutaneous disorders and neural dysfunction is disclosed. The preparation contains a nonionic, amphoteric or cationic surfactant in an...
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6589992 |
Inhibiting collagen-induced platelet aggregation
The present invention describes a therapeutic method useful for treating or preventing a condition of platelet aggregation in a subject including administering to the subject a pharmaceutically...
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6573302 |
Cream utilizing capsaicin
A cream comprising: a topical carrier wherein the topical carrier comprises a member selected from the group comprising lavender oil, myristal myristate, and other preservatives including,...
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6436996 |
Modulation of nitric oxide production
A method of treating cells that carry at least one APOE4 allele comprises increasing nitric oxide levels in the cells (e.g., by administering an exogenous source of nitric oxide to the cells) by an...
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6410597 |
Hydroxyalkyl amide analogs of ceramide
The present invention provides methods for treating disease conditions associated with abnormal cellular proliferation, inflammation and viral infection or proliferation by the administration of...
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6399073 |
Capsicum lachrymator
The present invention provides a capsicum containing lachrymator. The lachrymator comprises a nonflammable carrier and capsicum. The nonflammable carrier comprises propylene glycol, ethyl alcohol...
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6391909 |
Anandamide inhibitors as analgesic agents
Disclosed is a method of inhibiting anandamide amidase in an individual or animal and novel inhibitors of anandamide amidase. The disclosed method can be used to reduce pain in an individual or...
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6359010 |
Methods of treating anxiety and mood disorders with oleamide
A method of treating conditions characterized by anxiety and/or depression, by the administration of oleamide or related compounds is disclosed.
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6348502 |
Formulations for the treatment of gastro-oesophageal reflux
Formulations for the treatment of gastro-oesophageal reflux diseases include a carrier vehicle and an active gastro-protective agent. The carrier vehicle is either capable of forming a floating...
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6348501 |
Lotion compositions utilizing capsaicin
A lotion for treating the symptoms of arthritis using capsaicin and an analgesics, and a method for making.
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6284797 |
Topical treatment of pain and to promote healing
A topical therapeutic preparation includes capsaicin which is an extract of peppers or chiles and which is a potent local pain killer. The ointment also includes a norepinephrine inhibitor and...
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6262119 |
Methods of treating immunopathologies using polyunsaturated fatty acids
Method of treating or ameliorating symptoms of T-cell mediated disease wherein a composition comprising a therapeutically effective amount of a polyunsaturated fatty acid and a pharmaceutically...
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6255343 |
2,2-difluoro 15-hydroxyeicosatetraenoic acid analogs and methods of use
2,2-Difluoro HETE derivatives and methods of their use for treating dry eye are disclosed.
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6248788 |
Therapeutic method with capsaicin and capasicin analogs
Application of capsaicin (or a capsaicin analog) in a concentration from about 5% to about 10% by weight has been discovered to be an extremely effective therapy for treating neuropathic pain. In...
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6242012 |
Herbal composition for promoting hormonal balance in women and methods of using same
An herbal composition which can be used to alleviate the symptoms associated with hormonal imbalance in women contains supercritical extracts of ginger, rosemary and evening primrose oil, and...
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6239180 |
Transdermal therapeutic device and method with capsaicin and capsaicin analogs
Transdermal application of capsaicin (or a capsaicin analog) in a concentration from greater than about 5% to about 10% by weight has been discovered to be an extremely effective therapy for...
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6235788 |
Method for treating pre-malignant basal and squamous cell lesions of the epithelium
A new use of the botanical substance Capsaicin entails application of Capsaicin to pre-malignant basal and squamous cell lesions of the epithelium. Advantageous treatment, including atrophication...
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6201014 |
Therapeutically active compositions
A pharmaceutical composition for the treatment of irritable bowel syndrome, diarrhoea, constipation, abdominal pain and/or bloating or abdominal distension, the composition including a carrier...
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6197823 |
Pain reliever and method of use
A composition containing capsaicin together with other ingredients to neutralize the discomfort resulting from the application of capsaicin to the skin enabling treatment of many types of...
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6184252 |
2-amino-1,3-alkanediol compositions for inducing/stimulating hair growth and/or retarding hair loss
Topically applicable hair growth-/hair loss-affecting cosmetic/pharmaceutical compositions for treating mammalian subjects with hair or scalp disorders, comprise an effective amount of at least one...
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6140370 |
Stabilized alkyd based compositions containing halopropynl compounds
This invention pertains to the protection of nonaqueous compositions containing a transition metal from microbial spoilage using a stabilized antimicrobial composition comprising a halopropynyl...
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6103768 |
Fatty acid based compositions and methods for the control of plant infections and pests
The invention described here concerns the unique utility of fatty acids and their derivatives to eradicate existing fungal and bacterial infections in plants. Also, described herein are combination...
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6096784 |
Inhibitors of oleamide hydrolase
Inhibitors of oleamide hydrolase, responsible for the hydrolysis of an endogenous sleep-inducing lipid (1, cis-9-octadecenamide) were designed and synthesized. The most potent inhibitors possess an...
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6090854 |
Aryloxyanilides and related compounds
There is provided novel aryloxyanilides and related compounds of the formula ##STR1## wherein R 1 is --OR, --CO 2 R, or halogen with R being C 1 -4 alkyl; R 2 is R, cyclopropyl, C 2 -4...
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6069173 |
Synergistic insecticidal compositions comprising capsicum and synthetic surfactant and use thereof
Insecticidal compositions comprising a synthetic surfactant and capsaicin or other capsaicinoid exhibit synergistic effects against numerous insects, not only as to activity-enhancement effect but...
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6063381 |
Therapeutic uses of pungent botanicals and their related compounds
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6028112 |
Spirocyclopropyl fluorenes as melatonergic agents
There is provided novel spirocyclopropyl fluorene derivatives having the general Formula I ##STR1## wherein R, R 1 and X are as defined herein which are useful as melatonergic agents.
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6011067 |
Antioxidant composition for the treatment of psoriasis and related diseases
The present invention deals with the combination of several synergistic antioxidants including enzymatic co-factors as adjuncts to therapy of desquamating inflammatory disorders, such as psoriasis....
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6001375 |
Topical application of ceramides
The present invention discloses the topical application of ceramides. The present invention provides specific cosmetic compositions comprising a ceramide and an agent to target said ceramide to the...
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5994407 |
Procedure to prepare a solution with capsaicin
The present invention refers to a procedure to prepare a Capsaicin solution in various steps, preferentially three; the first steps consists in the preparation of the solution "A" by mixing 80...
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5985860 |
System for transdermal delivery of pain relieving substances
Compositions for pain relieving non-steroidal anti-inflammatory drugs and/or medicaments such as ibuprofen, methotrexate, capsaicin, diphenhydramine, aspirin, methyl-nicotinate and other...
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5977180 |
Anandamide analog compositions and method of treating intraocular hypertension using same
Anandamide analogues useful for the treatment of intraocular hypertension, as well as ophthalmic compositions comprising the same and a cyclodextrin, and methods of use of these compounds to treat...
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5968916 |
Fluoroalkenyl compounds and their use as pest control agents
Fluorinated alkene compounds useful for and methods of controlling nematodes, insects, and acarids that prey on agricultural crops. Polar compounds are particularly useful for systemic control of...
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