|
Match
|
Document |
Document Title |
|
|
5728392 |
Cosmetic and/or dermatological composition for the treatment of aging, containing ceramides, and the use thereof
Cosmetic or dermatological compositions containing at least one anti-aging active agent having an irritant effect, a cosmetically or dermatologically acceptable medium, and in addition, as an agent...
|
|
|
5679667 |
Aminoalcohols-N-Acyl derivatives as therapeutical agents against the neurogenic endoneural edema of the peripheral nerve
Aminoalcohols N-acyl derivatives useful in the prevention and in the treatment of mammalian pathologies induced by mast cell degranulation in consequence of peripheral nerve noxae.
|
|
|
5643899 |
Lipids for epidermal moisturization and repair of barrier function
Disorders of the skin and mucous membrane that have a disrupted or dysfunctional epidermal barrier are treated or prevented by topical application of a formulation comprising certain of the three...
|
|
|
5631297 |
Anandamides useful for the treatment of intraocular hypertension, ophthalmic compositions containing the same and methods of use of the same
Anandamides useful for the treatment of intraocular hypertension, as well as ophthalmic compositions comprising the same and a cyclodextrin, and methods of use of these compounds to treat...
|
|
|
5622927 |
Pharmaceutical composition and method for treating vulvitis or vulvovaginitis
The invention relates to a pharmaceutical composition for treating the symptoms of vulvitis and vulvovaginitis which comprises folic acid, panthenol and/or allantoin, protein hydrolysate or casein...
|
|
|
5621008 |
N-acyl-ethylene-triacetic acids
Disclosed is the novel use of N-acyl-N,N',N'-ethylenediaminetriacetic acids and N-acyl-N,N',N'-(ethylenedioxy) diethylenedinitrilotriacetic acids as active ingredients in preventative as well as...
|
|
|
5612380 |
Method for sleep induction
Sleep may be induced by administration of fatty acid primary amides, including cis-9,10-octadecenoamide. Furthermore, sleep deprivation may be assayed by analyzing cerebrospinal fluid with respect...
|
|
|
5612382 |
Composition for percutaneous absorption of pharmaceutically active ingredients
A pharmaceutical composition for transdermally delivering pharmaceutically active ingredients through skin or mucosal tissues. The composition comprises pharmaceutically active ingredients in...
|
|
|
5612061 |
Composition and method for the treatment of premenstrual syndrome
A composition for the treatment of premenstrual syndrome comprising an effective amount of calcium, magnesium, an analgesic and a diuretic sufficient to reduce the symptoms of premenstrual syndrome.
|
|
|
5610194 |
Insect repelling compositions comprising mixtures of an N-alkyl neoalkanamide and DEET
Insect repellent compositions are provided comprising mixtures of: (a) from about 5 to about 95%, by weight, of an N-alkyl neoalkanamide having the formula: ##STR1## wherein R 1 R 2 , and R 3 ...
|
|
|
5597840 |
Microemulsion formulation for injection into trees
An agrochemical microemulsion composition for injection into trees, and the use of said composition for preventing and treating damage to trees from disease and pests or regulating tree growth. The...
|
|
|
5596019 |
N-acyl-cycloalkylamine derivatives as melatonergics
Certain N-acyl-cycloalkylamine derivatives are useful as melatonergic agents.
|
|
|
5567735 |
Therapeutic amides
Amides having formula I: ##STR1## wherein E, X, R 2 and R 3 have the meanings given in the specification, and pharmaceutically acceptable salts and pharmaceutically acceptable in vivo...
|
|
|
5547984 |
N-Acetonyl-substituted-amides
Certain N-acetonyl-substituted-amides of the formula: ##STR1## wherein A is a heterocycle, a phenylalkyl, a phenylalkoxy, naphthyl, cycloalkyl, alkoxyalkyl, alkyl, haloalkyl or alkenyl group; X, Y...
|
|
|
5482965 |
Compositions and method comprising aminoalcohol derivatives as membrane penetration enhancers for physiological active agents
A method and compositions for enhancing absorption of topically administered physiologically active agents through the skin and mucous membranes of humans and animals in a transdermal device or...
|
|
|
5474757 |
Prevention of acetaminophen overdose toxicity with organosulfur compounds
A method of preventing acetaminophen (APAP)-induced hepatotoxicity utilizing diallyl sulfide (DAS) and diallyl sulfone (DASO 2 ) is disclosed. DAS and DASO 2 are prepared as an oral dosage form or...
|
|
|
5466712 |
Substituted n-aryl-1,2-diaminocyclobutene-3,4-diones
The compound of the formula (I) or a pharmaceutically acceptable salt thereof, are smooth muscle relaxants ##STR1##
|
|
|
5446027 |
Amide derivative and external skin care preparation containing the same
Amino derivatives represented by the following general formula (1): ##STR1## and external skin care preparations containing such an amide derivative, are useful for preventing or curing skin...
|
|
|
5436273 |
Psychoactive propargylamine derivatives used in the treatment of anxiety, psychotic states or aggression
Propargylamine derivatives having the general formula: ##STR1## wherein R is a hydrogen atom, an unsubstituted phenyl group or a phenyl group substituted with halogen, trifluoromethyl, loweralkoxy,...
|
|
|
5434190 |
N-aryl and N-cycloalkyl neoalkanamide insect repellents
N-monosubstituted neoalkanamides of 11 to 14 carbon atoms wherein the substituent on the amide nitrogen is cyclic (aromatic or cycloaliphatic, such as aryl or cycloalkyl) and of at least five...
|
|
|
5434189 |
N-alkyl neotridecanamide insect repellents
N-lower alkyl neoalkanamides of 1 to 2 carbon atoms in the lower alkyl thereof, and of 12 to 14 carbon atoms in the noalkanoyl group, e.g., N-methyl- and N-ethyl neotridecanamides, are new...
|
|
|
5416118 |
Bicyclic amides as inhibitors of acyl-coenzyme A: cholesterol acyl transferase
Novel bicyclic amides of the formula ##STR1## wherein Ar 1 and Ar 2 are phenyl, R 2 -substituted phenyl, heteroaryl or R 2 -substituted heteroaryl, wherein R 2 is 1 to 3 substituents...
|
|
|
5414017 |
Trifluoromethyl mercaptan and mercaptoacyl derivatives and method of using same
Compounds of the formula ##STR1## wherein m is zero or 1; n is zero, 1 or 2; p is zero or 1 to 6 provided that m and p are not both zero; R 3 is hydrogen, acyl, or benzyl; and R 1 is hydrogen,...
|
|
|
5411989 |
Nitric acid esters of cyclohexanol derivatives
The invention concerns nitric acid esters of cyclohexanol of formula I ##STR1## in which A signifies a valency bond or a C 1 -C 6 -alkylene chain and B the group --NR 1 --CO--Z, --NR 1 --SO 2 ...
|
|
|
5391578 |
N-lower alkyl neoalkanamide insect repellents
N-lower alkyl neoalkanamides are liquid state isomeric mixtures. Such new compounds are mixtures of isomeric secondary amides which have insect repellent properties, being especially effective...
|
|
|
5369030 |
Method of inducing cellular differentiations and altering cell phenotype using ceramide analogs
The present invention provides methods and pharmaceutical preparations of N-acyl-phenylaminoalcohol analogs for inducing differentiation of cells. Compositions having the formula ##STR1## wherein R...
|
|
|
5346887 |
Glaucoma treatment
A method and a composition for treating or reducing and/or controlling intraocular pressure comprising administering an effective amount of a renin inhibiting compound of the formula: ##STR1##...
|
|
|
5336271 |
Method for increasing the proportion of a crystalline organic compound which remains uncrystallized in a composite particulate product and suppressing recrystallization
A method for increasing the proportion of a crystalline organic compound which remains amorphous and suppressing recrystallization in which a crystalline organic compound and a hydrophilic polymer...
|
|
|
5318994 |
N-[2-(7-lower-alkoxynaphth-1-yl)ethyl]benzamides
Compounds of the formula: ##STR1## in which: A represents ##STR2## R represents linear or branched lower alkyl, R 1 represents hydrogen or linear or branched lower alkyl, and R 2 represents...
|
|
|
5302609 |
Treatment of diabetic nephropathy
The present invention is a novel method for the treatment of renal hypertrophy and hyperplasia associated with diabetic nephropathy. The method of the present invention generally comprises the...
|
|
|
5284876 |
Method of treating tardive dyskinesia using dopaminergic agents of prodrugs of therapeutic agents
This invention pertains to a method for treating a subject for Tardive Dyskinesia by administering a dopaminergic agent to the subject such that the dopaminergic agent enters the brain or by...
|
|
|
5284872 |
Nitrato alkanoic acid derivatives, methods for their production, pharmaceutical compositions containing the derivatives and medicinal uses thereof
New organic nitrate compounds, formed by condensing a nitrato alkanoic acid with a sulfur-containing amino acid or peptide followed by the reaction of the resulting product with an amino acid,...
|
|
|
5270310 |
N-aminoalkyl amide inhibitors of protein kinase C
The present invention provides methods for inhibiting protein kinase C which comprise contacting protein kinase C with an inhibitory amount of a compound having the formula ##STR1## wherein R 1 is...
|
|
|
5262436 |
Acylamino acid antihypertensives in the treatment of congestive heart failure
Mercapto-acylamino acids useful in the treatment of hypertension and combinations of mercapto-acylamino acids and atrial natriuretic factors or angiotensin converting enzyme inhibitors useful for...
|
|
|
5258408 |
Process of repelling insects from an area by application of N-alkyl neoalkanamide insect repellent thereto
N-lower alkyl neoalkanamides (N-lower alkyl trialkylacetamides of certain types) of 1 to 4 carbon atoms in the lower alkyl thereof and of 5 to 14 carbon atoms in the neoalkanoyl (or trialkylacetyl)...
|
|
|
5256697 |
Method of administering pyruvate and methods of synthesizing pyruvate precursors
A method for administering pyruvate is disclosed which comprises administering a therapeutically effective amount of a pyruvate precursor to a mammal in the form of pyruvamide or a pyruvyl-amino...
|
|
|
5254590 |
Acylaminophenol compounds
The invention relates to the compounds of formula (I): ##STR1## in which R represents higher alkyl, 1-(higher alkyl)lower cycloalkyl-1-yl or higher alkenyl comprising one or more double bonds, and...
|
|
|
5231087 |
Treatment of skin diseases and tumors with esters and amides of monocarboxylic acids
Noninfectious inflammatory and hyperpigmentation skin diseases, thermal injuries and premalignant skin tumors induced by radiation or virus, in both humans and animals, are treated with topical...
|
|
|
5221692 |
Ether linked and relatively nonpungent analogues of N-nonanoyl vanillylamide
The present invention provides a series of ether linked analogues of N-nonanoyl vanillylamide. They are found pharmaceutically effective in antinociceptive treatment and relatively nonpungent.
|
|
|
5208034 |
Tetraamides and method for improving feed utilization
Disclosed are novel tetraamide compounds and intermediates therefor which are useful in methods for improving feed conversion and/or weight gain in animals such as chickens.
|
|
|
5206225 |
Alkylcarboxylic acid dimethylamides as crystallization inhibitors
Crystallization of active material in spraying an aqueous solution of one of ##STR1## and is prevented by incorporation therein of an alkylcarboxylic acid dimethylamide of the formula ##STR2## in...
|
|
|
5182304 |
N-lower alkyl neodecanamide insect repellents
N-lower alkyl neoalkanamides (N-lower alkyl trialkylacetamides of certain types) of 1 to 4 carbon atoms in the lower alkyl thereof and of 5 to 14 carbon atoms in the neoalkanoyl (or trialkylacetyl)...
|
|
|
5151446 |
Substituted 2-amidotetralins as melatonin agonists and antagonists
The present invention relates generally to compounds having melatonin receptor activities and in particular to substituted 2-amidotetralin derivatives; to pharmaceutical preparations comprising...
|
|
|
5139784 |
Alkyl diamides and cosmetic treating compositions therewith
Comsetic compositions containing alkyl diamides for use in providing moisturizing and/or softening properties to treat dry human skin and for use in other cosmetic applications and including also...
|
|
|
5114978 |
Anhydrous blends of p-chloro-m-xylenol in surfactant mixtures
A composition, or an aqueous mixture containing a composition of a substantially anhydrous blends of parachlorometaxylenol, fatty acid diethanolamides, and anionic surfactants of the class...
|
|
|
5098934 |
Method of relieving pain with mercaptoalkanamides
Novel ω-mercaptopropanamides and their homologs of the formula ##STR1## wherein R 1 is selected from the group consisting of hydrogen and ##STR2## R 1 ' is selected from the group consisting of...
|
|
|
5084270 |
Cosmetic compositions containing N-alkoxyalkylamides
Cosmetic compositions containing N-alkoxyalkylamides for use in providing moisturizing and/or softening properties to treat dry human skin and for use in other cosmetic applications and including...
|
|
|
5079245 |
2-trifluoromethyl-7-substitute-6,7,8,9-tetrahydro-[5H]-benzocycloheptenes
The compounds 2-trifluoromethyl-7-substituted-6,7,8,9-tetrahydro-[5H]-benz
ocycloheptenes are disclosed and disclosed to be useful in the treatment of metabolic illnesses such as diabetes, obesity,...
|
|
|
5071875 |
Substituted 2-amidotetralins as melatonin agonists and antagonists
The present invention relates generally to compounds having melatonin receptor activities and in particular to substituted 2-amidotetralin derivatives; to pharmaceutical preparations comprising...
|
|
|
5068064 |
N-substituted lauramides, their preparation and compositions in which they are present
The invention relates to N-substituted lauramides. These compounds have the formula ##STR1## in which R 1 is a benzyl group and R 2 is an alkyl having from 1 to 4 carbon atoms, or R 1 and R 2 ...
|