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8163716 |
Method of administering hyaluronan formulation for the amelioration of osteophytes
Disclosed is a method for the amelioration of osteophyte formation including administering to a subject a therapeutically effective amount of an exogenous hyaluronan formulation.
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8153614 |
Treatment of osteoarthritis
There is provided a therapeutic agent for treating osteoarthritis, which is a drug comprising hyaluronan as an active ingredient. The hyaluronan is preferably a tetrasaccharide including two units,...
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8101196 |
Polysaccharide biomaterials and methods of use thereof
The invention includes a medical hydrogel made from polymerized polysaccharide macromers. The macromers are preferably polysaccharides decorated with polymerizable groups, for example,...
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8093227 |
Monosaccharide compounds and methods therefor
A monosaccharide compound of formula I as shown in the specification. Processes for the preparation of the compound of formula I and methods of screening for antibacterial or antibiotic compounds...
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8048865 |
Method and pharmaceutical to treat spinal discs
Methods for reducing chronic pain caused by a disrupted spinal disc are described. In one method, a physiologically acceptable amount of an injectable is injected into the disc. The injectable is...
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8034796 |
Glucosamine and glucosamine/anti-inflammatory mutual prodrugs, compositions, and methods
Mutual prodrugs of glucosamine, and derivatives and analogs of glucosamine and an anti-inflammatory agent, compositions thereof, and methods for, e.g., treating disorders and conditions by...
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8017162 |
Anti-inflammatory agent
This invention provides an anti-inflammatory agent or the like which is safer and less adverse and has the great effectiveness to prevent and treat arthritis, or the like. An anti-inflammatory...
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8003134 |
Ascorbic acid composition and method for treatment of aging or damaged skin
An ascorbic acid-based composition and related method for the treatment of aging or photo-damaged skin is disclosed. The composition includes water and ascorbic acid, at least a portion of which...
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7985741 |
Pharmaceutical composition comprising chito-oligomers
Compositions are provided comprising chito-oligomers obtainable from chitin, comprising oligomers of N-acetyl glucosamine (NAG) and glucosamine, wherein at least 50% of the oligomers have a chain...
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7947662 |
Folates, compositions and uses thereof
The present invention relates to folates, compositions and uses thereof; In particular, this invention describes a crystalline or amorphous compound which is a substituted or unsubstituted folate...
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7943598 |
Use of organic glucosamine salts
The present invention relates to the use of an organic glucosamine salt selected from glucosamine glucuronate, glucosamine ascorbate, glucosamine malate, glucosamine hydrogen malate, glucosamine...
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7943596 |
Medicinal composition for ophthal use containing acetylated hyaluronic acid
The present invention provides an ophthalmic pharmaceutical composition containing acetylated hyaluronic acid and a pharmacologically acceptable carrier. Preferably, the average molecular weight of...
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7928090 |
External preparation composition
An external preparation composition used for preventing or treating symptoms or diseases related to dermatopathy caused by dryness, UV rays and aging such as wrinkles and sags of the skin,...
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7923437 |
Water soluble β-glucan, glucosamine, and N-acetylglucosamine compositions and methods for making the same
Glucosamine, N-acetylglucosamine and β-glucan compositions suitable for human or animal consumption or use are disclosed. The glucosamine, N-acetylglucosamine and β-glucan compositions are d...
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7906493 |
Core 2 GlcNAc-T inhibitors
Method of treating conditions associated with raised activity of core 2 GlcNAc-T by administering an inhibitor of UDP-GlcNAc:Galβ1,3GalNAc-R (GlcNAc to GalNAc) β1,6-N-acetylglucosaminyl t...
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7902172 |
Method of promoting bone growth with hyaluronic acid and growth factors
A bone growth-promoting composition is provided comprising hyaluronic acid and a growth factor. The composition has a viscosity and biodegradability sufficient to persist at an intra-articular site...
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7893041 |
Oligosaccharide compositions and use thereof in the treatment of infection
Oligosaccharides and oligosaccharides linked to backbones such as proteins, methods for making such oligosaccharides and methods for using them to treat and/or prevent various disorders are described.
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7879335 |
Glycoconjugates, glycoamino acids, intermediates thereto, and uses thereof
The present invention provides novel n-alkenyl glycosides and glycoconjugates, n-alkyl glycoamino acids, and methods for the synthesis thereof. In another aspect, the present invention provides...
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7879824 |
Methods of preventing or treating diseases and conditions using complex carbohydrates
The invention relates to a method of preventing and treating diseases and conditions associated with allergies, autoimmunity, the adhesion cascade, the metastatic cascade or the coronary cascade...
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7862804 |
Admistration of C-glycoside compounds for depigmenting/whitening the skin
C-glycoside compounds having the formula (I): are useful for depigmenting/whitening the skin and/or for the anti-browning thereof.
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7858595 |
Anti-infectious carbohydrates
Neutral straight-chain or branched oligosaccharides for preventing the invasion and infection of mammal cells by pathogens and for fighting diseases caused by such pathogens are disclosed. Food,...
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7854934 |
Glycoconjugates, glycoamino acids, intermediates thereto, and uses thereof
The present invention provides novel glycosides and glycoconjugates, glycoamino acids, and methods for the synthesis thereof. In another aspect, the present invention provides novel clustered...
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7855188 |
Quarternized amino glucosamine compound for exerting anticancer effect
The present invention relates to the quaternized amino glucosamine, it can exert an anticancer effect via induction of apoptosis in a dose and time dependant manner through which an anticancer...
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7851458 |
Cartilage enhancing food supplements and methods of preparing the same
A food supplement, either in the form of a snack bar or a beverage, which contains one or more cartilage enhancing supplements is provided. The cartilage supplements include chondroitin,...
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7846914 |
Composition for the treatment and prevention of endothelial dysfunction
A composition and method for pain relief and the treatment and prevention of endothelial dysfunction the cause of atherosclerosis, cardiovascular disease, hypertension, and stroke in mammals...
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7834055 |
Compositions and methods for the treatment of skin
An ascorbic acid-based composition and related method for the treatment of aging, photo-damaged or inflamed skin is disclosed. The composition includes water and ascorbic acid, at least a portion...
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7824687 |
Clustered multi-antigenic carbohydrate constructs, methods for their preparation, and uses thereof
The present invention provides novel clustered multi-antigenic constructs having the structure: and methods for the synthesis thereof. In still another aspect, the present invention provides...
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7820639 |
Ophthalmic compositions including lubricant, deturgescent agent, and glycosaminoglycan and methods of using the same
Ophthalmic compositions are provided that include a lubricant, a deturgescent agent, a glycosaminoglycan, and water. Methods of using the ophthalmic compositions are also provided.
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7816402 |
Compositions and methods for the treatment of skin
An ascorbic acid-based composition and related method for the treatment of aging, photo-damaged or inflamed skin is disclosed. The composition includes water and ascorbic acid, at least a portion...
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7811999 |
Use of lipid conjugates in the treatment of diseases
This invention provides a method of treating a subject suffering from an obstructive respiratory disease, including the step of administering to a subject a compound comprising a lipid or...
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7803787 |
Composition and method for treating connective tissue damage by transmucosal administration
The present invention provides a composition, and a method of use thereof for treating connective tissue damage in man and in animals, which comprises a therapeutically effective amount of...
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7790102 |
Method for preparing a medical solution for the manufacture of a medicament for peritoneal dialysis
Method for preparing a medical solution, comprising the steps of a) providing a solution comprising one or more acetylated or deacetylated amino sugar/sugars in at least one compartment of a...
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7776366 |
Method and nutraceutical composition for mammals
A method is provided improving fertility in a mammal using glucosamine based composition. The composition is effective to improve fertility in mammals, including humans and stallions.
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7776842 |
Amino sugar chelates
The present invention includes amino sugar chelates and methods for preparing amino sugar chelates of the formula given below, where M is a metal; R2 and R3 are independently selected from H, OH...
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7776843 |
Therapeutic uses of glucan
The present invention is directed to methods of using glucan compositions, comprising water insoluble microparticulate glucans, in the treatment of bone injuries. The water insoluble...
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7772196 |
Use of lipid conjugates in the treatment of diseases
This invention provides a method of treating a subject suffering from a dermatologic condition, including, inter alia, psoriasis, contact dermatitis, and seboreic dermatitis, the method includes...
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7763595 |
Method of treatment of skin with external preparation composition
An external preparation composition used for preventing or treating symptoms or diseases related to dermatopathy caused by dryness, UV rays and aging such as wrinkles and sags of the skin,...
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7754256 |
Nutritional composition
A dietary supplement for dogs is disclosed. The composition is a blend of methyl sulfonyl methane, glucosamine sulfate, chondroitin sulfate, ascorbic acid, phylloquinone, yucca powder and...
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7732414 |
C-glycoside compounds for stimulating the synthesis of glycosaminoglycans
C-glycoside compounds are suited for stimulating the synthesis of glycosaminoglycans containing a D-glucosamine and/or N-acetyl-D-glucosamine residue, advantageously hyaluronic acid, and/or...
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7727973 |
Lipid A-type compound and composition containing it
Compounds of the formula: and compositions containing one or more such compounds, the compositions preferably being suitable for topical application to the skin.
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7704976 |
Use of N-acetyl-D-glucosamine for preparing medicines for urogenital tract infection's treatment and prevention
The present invention discloses a use of N-acetyl-D-glucosamine in the manufacture of a medicament for treatment of urogenital tract infection. N-acetyl-D-glucosamine exhibits a function of...
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7687249 |
Polysaccharide derivatives with high antithrombotic activity in plasma
The present invention relates to a process for the preparation of sulphated glycosaminoglycans derived from N— acetylheparosan which comprises: a) N-deacetylation and N-sulphation of the N...
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7683042 |
Stabilized halide-free glucosamine base and method of preparation
A stabilized glucosamine base composition comprising a glucosamine base having a purity level of at least 99.0 wt. % and a maximum halide content of about 0.01 wt. % coated with at least one...
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7683038 |
Percarboxylated polysaccharides, and a process for their preparation
The present invention relates to percarboxylated polysaccharide selected from the group consisting of gellan, carboxymethylcellulose, pectic acid, pectin and hyaluronic acid derivatives; the...
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7671041 |
Hydrolysate of avian cartilage, process of preparation and uses thereof
This invention relates to a hydrolysate of avian cartilage comprising 45% to 70% by weight of hydrolysed type II collagen, 9% to 15% by weight of chondroitin sulphate, 0.5% to 2% in weight of...
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7662802 |
Halide-free glucosamine-acidic drug complexes
A complex of glucosamine having a purity of at least about 99 wt. % and a maximum halide content of about 0.01 wt. %, and a therapeutic drug having a pKa of less than 7. Preferably, the complex is...
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7662803 |
Method for treating warm-blooded vertebrates with halide-free glucosamine-acidic drug complexes
A method of treating a warm-blood vertebrate. The vertebrate may be a human being or a lower animal. The treatment method involves administering to the vertebrate in need of such treatment a...
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7659260 |
Tamponade compositions and methods for retinal repair
Described herein are methods of repairing retinal tissue using resorbable tamponade compositions that are heavier than aqueous humor and contain one or more glysosaminoglycans.
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7658952 |
Dialysis solutions containing pyrophosphates
Dialysis solutions comprising pyrophosphates and methods of making and using the dialysis solutions are provided. In an embodiment, the present disclosure provides a dialysis solution comprising a...
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7655445 |
Methods for synthesis of sulfated saccharides
The present invention provides methods, processes and reaction mixtures, which produce sulfated heparosan polysaccharides. This invention also provides methods and reaction mixtures for the...
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