Patents in Class 514/613

Matches 1 - 50 out of 310

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Match	Document	Document Title
1	7612141	Hair cleansing composition Provided is a hair cleansing composition comprising (A) an amphipathic amide lipid, (B) an anionic surfactant and (C) a silicone. The hair cleansing composition of the present invention has...
2	7592373	Amide compounds with MCH antagonistic activity and medicaments comprising these compounds Compounds of formula (I) wherein A, B, b, W, X, Y, Z, R 1 , R 2 , and R 3 have the meanings given in claim 1 , pharmaceutical compositions these compounds, and methods of preventing or...
3	7592365	Substituted pyrroles, compositions containing same, method for making same and use thereof The disclosure concerns substituted pyrroles of formula (I): wherein A, L, Ar, R1, R2, R5, and Ra are as defined in the disclosure, compositions containing the same, methods for making the same...
4	7582306	Pseudoceramides and cosmetic compositions comprising the same The present invention relates to a pseudoceramide represented by the following formula (I) and a cosmetic composition comprising the same: wherein Z represents —OH and Y represents...
5	7579379	CETP activity inhibitors The present invention provides a CETP activity inhibitor comprising as an active ingredient a compound represented by the formula (I): wherein R represents a straight chain or branched alkyl...
6	7576103	Tetralin and indane derivatives and uses thereof Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, p, q, Ar, R 1 and R 2 are as defined herein. Also provided are methods for preparing, compositions...
7	7550490	Benzamide derivatives as histone deacetylase inhibitors with potent differentiation and anti-proliferation activity The present invention is related to the preparation and pharmaceutical use of novel benzamide derivatives as defined in the specification of formula (I) as histone deacetylase inhibitors (HDACI),...
8	7538141	Compounds for the treatment of diseases The invention relates to compounds of formula (1) and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives....
9	7538081	Method and agent for enhancing diffusivity and long-lasting property of fragrance A fragrance composition having an excellent diffusivity and long-lasting property of fragrance and a cosmetic, toiletry, bath composition, food and drink and pharmaceutical having an excellent...
10	7524885	Compounds that stimulate glucose utilization and methods of use The invention provides novel compounds of the Formula (I) that stimulate rates of glucose oxidation in myocardial cells: wherein W, Cyc, p, Y, X, Z, R, R 1 , R 2 , R 3 , R 4 , I, m and n...
11	7517913	Polyamine conjugates with acidic retinoids and preparation thereof Invented are novel polyamine conjugates which have been readily obtained using as key-step the condensation of linear, conformationally restricted, cyclic and branched polyamines or suitably...
12	7485315	Compositions comprising a compound of low solubility and a lipophilic amino acid derivative, uses thereof and process for dissolving a compound of low solubility The invention relates to a process for dissolving at least one compound of low solubility in water, the said process comprising the essential step of mixing the compound of low solubility with at...
13	7482378	Physiological cooling compositions The present invention provides, in one aspect, a physiological cooling composition comprising at least one cyclohexane carboxamide, at least one acyclic carboxamide, and at least one stereoisomer...
14	7482160	Process of making a compound by forming a polymer from a template drug A method of forming polymers in the presence of nucleic acid using template polymerization. These methods can be used for the delivery of nucleic acids, for condensing the nucleic acid, for forming...
15	7465754	Method of potentiating chemotherapy and treating solid tumors This invention provides a method of treating solid tumors which comprises administering an effective amount of a combination of (1) a bioresponse modifier and (2) a chemotherapeutic agent. This...
16	7449315	Bifunctional energy-reversible acyl-compositions Energy-reversible acyl conjugates, intermediates, and related compositions are disclosed. In preferred aspects, examples of such compositions include:
17	7439394	Cyclohexyl-1,4-diamine compounds Novel cyclohexyl-1,4-diamine compounds corresponding to formula I, processes for the production thereof, pharmaceutical compositions containing these compounds, methods of producing...
18	7435851	Puleganic amides The present invention provides substituted puleganic amides and compositions thereof, which are both useful as a topical treatment for skin, such as a repellant for insects and arthropods.
19	7432307	Modulators of retinol-retinol binding protein (RBP)-transthyretin (TTR) complex formation Described herein are methods and compositions for the detection of transthyretin (TTR), retinol binding protein (RBP) and retinol complex formation. The methods and compositions described herein...
20	7429618	Potassium channel modulators This invention relates to novel compounds useful as potassium channel modulators. More specifically the invention provides chemical compounds useful as modulators of SK Ca and/or IK Ca channels.
21	7425578	Immunoregulatory compounds and derivatives and methods of treating diseases therewith Compounds are disclosed having the structure of Formula I: where R 1 , R 3 , and R 4 are independently hydrogen or C 1 to C 4 alkyl, and R 2 is: where R 5 is selected from the group...
22	7423177	Carboxamide derivatives as therapeutic agents This invention provides certain compounds, methods of their preparation, pharmaceutical compositions comprising the compounds, and their use in treating human or animal disorders. The compounds of...
23	7414152	N-substituted p-menthane carboxamides Cooling compounds are provided having the formula: wherein, m is 0 or 1, Y and Z are selected independently from the group consisting of H, OH, C1-C4 straight or branched alkyl, and a C1-C4...
24	7388029	Compositions and methods for treating hair loss using non-naturally occurring prostaglandins A method for treating hair loss in mammals uses compositions containing prostaglandin F analogs. The compositions can be applied topically to the skin. The compositions can arrest hair loss,...
25	7368478	Methods for inhibiting angiogenesis and tumor growth Angiogenesis, tumor growth, and metalloproteinase 2 (MMP2) interaction with integrin-α v β 3 are inhibited by an inhibitor compound of formula: wherein G 1 and G 2 are each independently...
26	7361688	Substituted aminoalcohols useful in treatment of Alzheimer's disease The invention provides compounds of formula (I): useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful...
27	7348353	Acetylene derivatives having mGluR 5 antagonistic activity The invention provides compounds of formula (I) wherein m, n, A, R, R′, R″, R 0 , X and Y are as defined in the description, and their preparation. The compounds of formula (I) are useful as...
28	7326732	EP2 receptor agonists A compound of formula (I): or a salt, solvate and chemically protected form thereof, wherein: R 5 is an optionally substituted C 5-20 aryl or C 4-20 alkyl group; A is selected from...
29	7294643	UK-1 analogues: methods of preparation and use The present invention includes a number of structural analogues of UK-1. A comparision of the anticancer activity of the UK-1 analogues with their ability to inhibit the growth of...
30	7288262	Composition comprising a cyclohexane-based compound, compound and use of said compound to structure a composition Compositions, in particular cosmetic compositions, comprising a cyclohexane-based compound defined by formula (I): wherein: R, which may be identical or different, are each chosen from...
31	7271196	CETP activity inhibitors The present invention provides a CETP activity inhibitor comprising as an active ingredient a compound represented by the formula (I): wherein R represents a straight chain or branched alkyl...
32	7253210	Methylene-bridged selective androgen receptor modulators and methods of use thereof This invention provides a class of androgen receptor targeting agents (ARTA). The agents define a new subclass of compounds, which are selective androgen receptor modulators (SARM). Several of the...
33	7244751	Histone deacetylase inhibitors of novel benzamide derivatives with potent differentiation and anti-proliferation activity The present invention is related to the preparation and pharmaceutical use of novel benzamide derivatives as defined in the specification of formula (I) as histone deacetylase inhibitors (HDACI),...
34	7241802	Substituted cyclohexylcarboxylic acid amide compounds Substituted cyclohexylcarboxylic acid amide compounds, processes for their production, pharmaceutical compositions containing these compounds and the use of substituted cyclohexylcarboxylic acid...
35	7223746	Omega cycloalkyl 17-heteroaryl prostaglandin E2 analogs as EP2-receptor agonists The invention relates to the use of derivatives of E-type prostaglandins as EP 2 agonists, in general, and, in particular as ocular hypotensives. The PGE derivatives used in accordance with the...
36	7192983	N-protected/N-substituted-beta-amino hydroxy sulfonates N-protected/N-substituted alpha-amino aldehydes, which are useful as pharmaceuticals and pharmaceutical intermediates, can be stored and shipped in a more stable form as...
37	7179455	Pesticide in gel form The invention relates to a bait matrix which includes a gelling agent and a pesticide. The bait matrix is useful for controlling pests by attracting and poisoning them. The gel matrix is...
38	7173063	Topoisomerase poisons for the treatment of proliferative disorders Methods for the treatment of a proliferative disorder are provided in which a subject in need of such treatment is administered an effective amount of a compound selected from: compounds of formula...
39	7160922	Hemihydrate of a selective functional M1 muscarine receptor agonist The present invention provides crystalline biphenyl-4-carboxylic acid (R)-(6-(1-((4-fluorobenzyl)methylamino)ethylideneamino)-2(R) -hydroxyindan-1-yl)amide hemihydrate, compositions thereof,...
40	7151117	Concentrated X-ray contrast media can act as universal antigens and can inhibit or prevent allergic reactions The present application is directed to the use of X-ray contrast media that act as universal antigens that are labeled herein as “pseudoantigens.” X-ray contrast media have the potential to...
41	7151095	Immunoregulatory compounds and derivatives and methods of treating diseases therewith Compounds are disclosed having the structure of Formula I: where R 1 , R 3 , and R 4 are independently hydrogen or C 1 to C 4 alkyl, and R 2 is: where R 5 is selected from the group...
42	7132454	HEXIM1 as a suppressor of HIV replication and cardiac hypertrophy Cellular transcription is modulated by increasing or decreasing the amount of active HEXIM1 in the cell. The methods are applied to the treatment of HIV infection and cardiac hypertrophy. Assays...
43	7119120	Phosphate transport inhibitors Disclosed are compounds which have been identified as inhibitors of phosphate transport. Many of the compounds are represented by Structural Formula (I):
44	7115660	Methods for inhibiting angiogenesis and tumor growth Angiogenesis, tumor growth, and metalloproteinase 2 (MMP2) interaction with integrin-α v β 3 are inhibited by an inhibitor compound of formula (I): wherein G 1 and G 2 are each independently...
45	7108867	Process for preparing particles A process for preparing particles of a substance, such as a protein or polypeptide, comprising: (a) preparing a first liquid comprising water, the substance and a modulator, wherein the modulator...
46	7105539	Derivatives of succinic and glutaric acids and analogs thereof useful as inhibitors of phex The present invention relates to derivatives of succinic and glutaric acids and analogues thereof, having the following general formula: useful as inhibitors of PHEX. These derivatives are...
47	7101895	Cyclohexyl sulphone derivatives as gamma-secretase inhibitors Compounds of formula I: wherein Ar 1 and Ar 2 are optionally substituted aryl or heteroaryl, L is a bond, ═CH— or —(CHR a ) n —, and X is SCN, SR 1 , S(O)R 1 , (CR a R b ) m SO 2 R 1...
48	7074833	Use of the (1S,2R) enantiomer of milnacipran for the preparation of a drug A method for treating or preventing a disorder or a condition by double inhibition of serotonin (5-HT) and noradrenaline (NA) reuptake in a subject in need thereof, while limiting the risks of...
49	7074780	Substituted phenylcyclohexanecarboxamides and their use The present invention relates to substituted phenylcyclohexanecarboxamides of the formula (I) to processes for their preparation and to their use in medicaments, in particular for the...
50	7049317	CCR-3 receptor antagonists The invention provides compounds of Formula (I): wherein R 1 –R 4 have any of the values defined in the specification that are CCR-3 receptor antagonists, pharmaceutical compositions...

Matches 1 - 50 out of 310

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