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8163705 |
Glycolipid and use thereof
The present invention provide a compound represented by the following formula (1) wherein each symbol is as defined in the specification, or a salt thereof. The compound of the present invention...
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8163299 |
Stabilized pharmaceutical product
Use of an adsorbent and a sealed package (e.g. an overwrap) to protect a pharmaceutical product in a solid state in the presence of a reducing sugar.
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8153614 |
Treatment of osteoarthritis
There is provided a therapeutic agent for treating osteoarthritis, which is a drug comprising hyaluronan as an active ingredient. The hyaluronan is preferably a tetrasaccharide including two units,...
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8148350 |
Carbohydrate composition for flat glucose response
A low-glycemic available carbohydrate composition of the invention contains the following components: (i) 5-60 wt. % of one or more monosaccharides selected from monosaccharides other than glucose...
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8143235 |
Use of dietary fibres against muscle wasting
A composition nutritional containing dietary fibres is useful for the treatment of muscle wasting, if the dietary fibre comprise at least 30 wt. % of galacto-oligosaccharides or other...
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8097591 |
Polysialic acid derivatives, methods of production, and uses in enhancing cancer antigen production and targeting
The present invention relates to compositions and methods of their production and use, including use in increasing de-N-acetyl sialic acid antigen of a mammalian cell and methods that exploit the...
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8063026 |
Method of palliating lower urinary tract infections by treatment with mannan oligosaccharides
Provided herein are methods of using mannan oligosaccharides, to treat, palliate, relieve, prevent and/or eliminate urinary tract infections of humans. A mixture of oligosaccharides derived from...
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8026221 |
Method, composition and kit for antigenic binding of norwalk-like viruses
A method for detecting a Norwalk-Like Virus (NLV) in a biological sample, comprising the steps of: obtaining a biological sample suspected of containing a NLV; contacting the biological sample with...
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8008275 |
Fucose containing proteoglycan or acidic glycan and their pharmaceutical use
A class of proteoglycans containing fucosylated acidic glycans, e.g., as produced by marine sponges and sea urchin embryos, have been found to stimulate selective proliferation of mammalian natural...
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7998943 |
Core 2 GlcNAc-T inhibitors III
A method of treating a subject in need of therapy for a condition involving detrimental activity of the enzyme core 2 GlcNAc-T is provided, comprising administration of a therapeutically effective...
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7994155 |
Accelerator for mineral absorption and use thereof
The present invention has an object to provide an accelerator for mineral absorption and a composition containing the accelerator. The object is solved by providing an accelerator for mineral...
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7956045 |
Compositions and methods for animal treatment
A method of improving the health and production of ruminant animals, the method including the step of orally administering to the animal an effective amount of an indigestible oligosaccharide...
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7932236 |
Glycolipids
Novel synthetic gangliosides and pharmaceutical compositions containing such synthetic gangliosides are described. Methods of making the novel synthetic ganglioside compounds and compositions as...
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7919479 |
Antiadhesive carbohydrates
Provided is a pharmaceutical or dietetic product, which serves for reducing and/or blocking the adhesion of pathogenic substances and organisms to eucaryontic cells, in particular mammal cells....
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7915235 |
High affinity ligands bind to clostridium difficile toxin A
Glycans are identified which have high affinity for C. difficile toxin A. They share one of two saccharide backbones and may have additional side chains. The backbones are galactose-β1-3 ...
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7906493 |
Core 2 GlcNAc-T inhibitors
Method of treating conditions associated with raised activity of core 2 GlcNAc-T by administering an inhibitor of UDP-GlcNAc:Galβ1,3GalNAc-R (GlcNAc to GalNAc) β1,6-N-acetylglucosaminyl t...
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7893041 |
Oligosaccharide compositions and use thereof in the treatment of infection
Oligosaccharides and oligosaccharides linked to backbones such as proteins, methods for making such oligosaccharides and methods for using them to treat and/or prevent various disorders are described.
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7851438 |
Erythropoietin compositions
Methods and materials are provided for the production of compositions of erythropoietin protein, wherein said compositions comprise a pre-selected N-linked glycosylation pattern as the predominant...
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7842678 |
Compositions comprising oligosaccharides
The present invention concerns compositions comprising a saccharide for the inhibition of pathogen adhesion to mammalian cells.
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7842677 |
Synthetic ganglioside derivatives and compositions thereof
Novel synthetic gangliosides and pharmaceutical compositions containing such synthetic gangliosides are described. Methods of making the novel synthetic ganglioside compounds and compositions as...
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7833753 |
Methods of producing erythropoietin isoforms comprising Lewis-X structures and high sialic acid content and compositions of the same
Disclosed are immortalized human embryonic retina cells, having a nucleic acid sequence encoding an adenoviral E1A protein integrated into the genome of the cells, and further comprising a nucleic...
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7820628 |
Tumor lesion regression and conversion in situ into autologous tumor vaccines by compositions that result in anti-Gal antibody binding
The present invention discloses that an intratumoral injection of: i) glycolipids with α-gal epitope; ii) gene vectors comprising an α1,3galactosyltransferase gene; or iii) a mixture of α...
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7820629 |
Galactose derivative, drug carrier and medicinal composition
The object of the present invention is to provide a novel and useful galactose derivative, which is a component of a drug carrier by which a medicine can be efficiently transferred into the liver,...
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7811999 |
Use of lipid conjugates in the treatment of diseases
This invention provides a method of treating a subject suffering from an obstructive respiratory disease, including the step of administering to a subject a compound comprising a lipid or...
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7776842 |
Amino sugar chelates
The present invention includes amino sugar chelates and methods for preparing amino sugar chelates of the formula given below, where M is a metal; R2 and R3 are independently selected from H, OH...
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7772212 |
Isomaltooligosaccharides to inhibit avian pathogenic intestinal bacteria
Isomaltooligosaccharides (IMOs) produced by Leuconostoc mesenteroides ATCC 13146 fermentation with a sucrose:maltose ratio of 2:1 have been discovered to be effective prebiotics in mixed cultures...
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7772196 |
Use of lipid conjugates in the treatment of diseases
This invention provides a method of treating a subject suffering from a dermatologic condition, including, inter alia, psoriasis, contact dermatitis, and seboreic dermatitis, the method includes...
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7759324 |
Antiadhesive carbohydrates
Provided is a pharmaceutical or dietetic product, which serves for reducing and/or blocking the adhesion of pathogenic substances and organisms to eucaryontic cells, in particular mammal cells....
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7736673 |
Stabilized pharmaceutical product
The invention relates to the use of an adsorbent and a sealed package, for example an overwrap, to protect a pharmaceutical product in a solid state in the presence of a reducing sugar.
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7727962 |
Powder comprising new compositions of oligosaccharides and methods for their preparation
The present invention concerns powders containing a pharmaceutical active substance and a combination of excipients comprising at least one 1,4 O-linked saccharose derivative selected from the...
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7723306 |
Spray-dried powder comprising at least one 1,4 O-linked saccharose-derivative and methods for their preparation
The present invention relates to a spray-dried powder and method for its manufacture. A spray dried powder containing a pharmaceutical active substance and one or more 1,4 O-linked saccharose...
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7687458 |
Pharmaceutical compositions of hydrophobic compounds
This invention concerns novel methods of enhancing the solubility of a compound. Compositions prepared using such methods are also disclosed. Compositions prepared using the methods have various...
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7659259 |
Method of treating inflammation of the eye
The present invention includes a method of treating inflammation of the eye comprising administering to an eye of a patient suffering from inflammation of the eye, a composition comprising an...
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7638488 |
Use of alpha-glucosidase inhibitors to treat alphavirus infections
The present invention provides methods for treating a flavivirus infection, including hepatitis C virus (HCV) infection, in an individual suffering from a flavivirus infection. In some embodiments,...
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7638503 |
Small molecule stimulators of neuronal growth
Provided herein are small molecule stimulators of neuronal growth, their preparation, and their use for treatment of neurological disorders. In one embodiment, provided herein are methods of...
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7618951 |
Use of prebiotics, preferably glucooligosaccharide, for the prevention of the onset of type II diabetes
The invention relates to the use of prebiotics for the preparation of food or pharmaceutical compositions which are intended for the treatment and/or prevention of hyperglycaemic syndromes and, in...
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7608436 |
Process for producing saccharide oligomers
A process for preparing saccharide oligomers uses an aqueous feed composition that comprises at least one monosaccharide or linear saccharide oligomer, and has a solids concentration of at least...
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7528113 |
Method and composition for the treatment of adenoviral ocular infections
Adenoviral infections and in particular ocular adenoviral infections, e.g. keratoconjunctivitis, can be treated or alleviated by the administration of a substance, interfering with the interaction...
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7476660 |
Composition and method for organ preservation
The present invention relates to a composition for organ preservation, comprising an inulin type fructan as an active ingredient. The composition for organ preservation can suppress the...
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7417031 |
Use of algae-derived physiologically active substances for treating a carcinomatous disease
Medicinal compositions for treating, ameliorating or preventing diseases with sensitivity to 3,6-anhydrogalactopyranose represented by formula (1): foods, drinks, cosmetics, etc. containing as the...
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7402575 |
Methods of treating inflammation
Methods and compositions for treating myocardial dysfunction or inflammation are described. The methods of the invention involve administering an agent that can inhibit lysozyme to an animal in...
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7375095 |
Sugar derivative
For extending the uses of a compound represented by Chemical formula 1, the object of the present invention is to provide a derivative of cyclic tetrasaccharide whose physicochemical properties are...
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7326182 |
Method of using device for bio-affinity material for treatment of blood or plasma
Bio-affinity material containing at least one biologically active saccharide which is covalently bound via at least one spacer to a cross-linked matrix and that the material is autoclaved....
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7309697 |
Cyclic maltosylmatose
An object of the present invention is to provide an option of non-reducing saccharide by providing a novel non-reducing saccharide composed of glucose as constituents and to provide a novel enzyme...
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7297680 |
Compositions of erythropoietin isoforms comprising Lewis-X structures and high sialic acid content
Disclosed are immortalized human embryonic retina cells, having a nucleic acid sequence encoding an adenoviral E1A protein integrated into the genome of the cells, and further comprising a nucleic...
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7291607 |
Isomaltooligosaccharides from Leuconostoc as neutraceuticals
Isomaltooligosaccharides (IMOs) produced by Leuconostoc mesenteroides ATCC 13146 fermentation with a sucrose:maltose ratio of 2:1 have been discovered to be effective prebiotics in mixed cultures...
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7271158 |
Treatment of rumen acidosis with α-amylase inhibitors
The invention described herein relates to: the use of an effective inhibitor of a bacterial α-amylase and/or α-glucosidase in the manufacture of a composition for the treatment of acidosis; a m...
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7202219 |
Use of D-tagatose as a prebiotic food component
Oral intake of D-tagatose in a prebiotic food induces production of butyrate and stimulates the growth of beneficial bacteria in the human colon. Therefore it is believed to be useful in food or...
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7192937 |
Oligosaccharide-containing compositions and uses thereof
The use of compositions containing one or more oligosaccharides in an amount effective to disinfect and/or preserve medical devices, pharmaceutical preparations, and the like is described. Buffered...
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7182954 |
Prebiotic oligosaccharides via alternansucrase acceptor reactions
Oligosaccharides produced by an alternansucrase enzyme catalyzed reaction of sucrose with an acceptor oligosaccharide are effective as prebiotics for controlling enteric bacterial pathogens....
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